Radiomic Phenotype of Periatrial Adipose Tissue in the Prognosis of Late Postablation Recurrence of Idiopathic Atrial Fibrillation.

IF 1.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Sovremennye Tehnologii v Medicine Pub Date : 2023-01-01 Epub Date: 2023-03-29 DOI:10.17691/stm2023.15.2.05
J N Ilyushenkova, S I Sazonova, E V Popov, R E Batalov, S M Minin, A B Romanov
{"title":"Radiomic Phenotype of Periatrial Adipose Tissue in the Prognosis of Late Postablation Recurrence of Idiopathic Atrial Fibrillation.","authors":"J N Ilyushenkova, S I Sazonova, E V Popov, R E Batalov, S M Minin, A B Romanov","doi":"10.17691/stm2023.15.2.05","DOIUrl":null,"url":null,"abstract":"<p><p><b>The aim of the study</b> is to find new predictors of postablation atrial fibrillation (AF) recurrence in patients with lone AF using a texture analysis of the periatrial adipose tissue (PAAT) of the left atrium.</p><p><strong>Materials and methods: </strong>Forty-three patients admitted for lone AF catheter ablation, who had undergone multispiral coronary angiography, were enrolled in the study. PAAT segmentation was performed using 3D Slicer application followed by extraction of 93 radiomic features. At the end of the follow-up period, patients were divided into 2 groups depending on the presence or absence of AF recurrence.</p><p><strong>Results: </strong>12 months of follow-up after catheter ablation, postablation AF recurrence was reported in 19 out of 43 patients. Of 93 extracted radiomic features of PAAT, statistically significant differences were observed for 3 features of the Gray Level Size Zone matrix. At the same time, only one radiomic feature of PAAT, Size Zone Non Uniformity Normalized, was an independent predictor of postablative recurrence of AF after catheter ablation and 12 months of follow-up (McFadden's R<sup>2</sup>=0.451, OR - 0.506, 95% CI: 0.331‒0.776, p<0.001).</p><p><strong>Conclusion: </strong>The radiomic analysis of periatrial adipose tissue may be considered as a promising non-invasive method for predicting adverse outcomes of the catheter treatment, which opens the possibilities for planning and correction of patient management tactics after intervention.</p>","PeriodicalId":51886,"journal":{"name":"Sovremennye Tehnologii v Medicine","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306967/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sovremennye Tehnologii v Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17691/stm2023.15.2.05","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/3/29 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0

Abstract

The aim of the study is to find new predictors of postablation atrial fibrillation (AF) recurrence in patients with lone AF using a texture analysis of the periatrial adipose tissue (PAAT) of the left atrium.

Materials and methods: Forty-three patients admitted for lone AF catheter ablation, who had undergone multispiral coronary angiography, were enrolled in the study. PAAT segmentation was performed using 3D Slicer application followed by extraction of 93 radiomic features. At the end of the follow-up period, patients were divided into 2 groups depending on the presence or absence of AF recurrence.

Results: 12 months of follow-up after catheter ablation, postablation AF recurrence was reported in 19 out of 43 patients. Of 93 extracted radiomic features of PAAT, statistically significant differences were observed for 3 features of the Gray Level Size Zone matrix. At the same time, only one radiomic feature of PAAT, Size Zone Non Uniformity Normalized, was an independent predictor of postablative recurrence of AF after catheter ablation and 12 months of follow-up (McFadden's R2=0.451, OR - 0.506, 95% CI: 0.331‒0.776, p<0.001).

Conclusion: The radiomic analysis of periatrial adipose tissue may be considered as a promising non-invasive method for predicting adverse outcomes of the catheter treatment, which opens the possibilities for planning and correction of patient management tactics after intervention.

Abstract Image

Abstract Image

Abstract Image

心房周围脂肪组织在特发性心房颤动消融术后晚期复发预后中的放射学表型
本研究的目的是通过对左心房周围脂肪组织(PAAT)的纹理分析,找到预测单发房颤患者消融术后房颤复发的新指标:43名接受过多螺旋冠状动脉造影术的孤发房颤导管消融患者被纳入研究。使用 3D Slicer 应用程序对 PAAT 进行分割,然后提取 93 个放射学特征。随访结束时,根据房颤复发与否将患者分为两组:结果:导管消融术后随访 12 个月,43 例患者中有 19 例出现消融术后房颤复发。在提取的 93 个 PAAT 放射学特征中,灰度级大小区矩阵的 3 个特征在统计学上存在显著差异。同时,只有 PAAT 的一个放射学特征--尺寸区不均匀度归一化--是导管消融术后和 12 个月随访后房颤术后复发的独立预测因子(麦克法登 R2=0.451,OR - 0.506,95% CI:0.331-0.776,p):心房周围脂肪组织的放射学分析可被视为预测导管治疗不良后果的一种很有前途的非侵入性方法,它为规划和纠正干预后的患者管理策略提供了可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Sovremennye Tehnologii v Medicine
Sovremennye Tehnologii v Medicine MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
1.80
自引率
0.00%
发文量
38
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信