{"title":"Tratamiento de sobrecrecimiento bacteriano en el intestino delgado en pacientes chilenos con síndrome de intestino irritable: un estudio prospectivo y comparativo","authors":"C. von Muhlenbrock , G. Landskron , A.M. Madrid","doi":"10.1016/j.rgmx.2024.08.004","DOIUrl":"10.1016/j.rgmx.2024.08.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Patients with disorders of the gut-brain axis, such as irritable bowel syndrome (IBS), often exhibit small intestinal bacterial overgrowth (SIBO). Its treatment includes rifaximin (RF), ciprofloxacin (CF), neomycin, sulfamethoxazole-trimethoprim, and metronidazole (MZ). RF is a non-absorbable antibiotic, postulated to have fewer adverse effects. Our aim was to assess symptomatic response and SIBO eradication in patients with IBS, using three antibiotic regimens.</div></div><div><h3>Methods</h3><div>A prospective, randomized, double-blind study was conducted on IBS patients over 18 years of age, utilizing the Rome IV questionnaire and lactulose breath test. Those diagnosed with SIBO were randomly assigned to receive antibiotic treatment. Group A was treated with RF, group B with CF, and group C with MZ, each for 10 days. Treatment response was evaluated based on the SIBO eradication rate 15 days after completing therapy, utilizing hydrogen and methane breath tests with lactulose. Self-reported symptoms were recorded on a 10-point Likert scale before, during, and after treatment.</div></div><div><h3>Results</h3><div>Ninety-seven patients with IBS and SIBO were included, 81% of whom completed treatment. Fifty-nine percent of the patients treated with RF achieved SIBO eradication, compared with 53% and 79% of those treated with CR and MZ, respectively. Metronidazole reduced more methane levels, compared with the other groups. However, the greatest reduction in abdominal pain and bloating was observed in the RF group, with a lower percentage of adverse events.</div></div><div><h3>Conclusions</h3><div>Patients with IBS and SIBO benefit from antibiotic therapy. MZ exhibited the best SIBO eradication rate, but RF demonstrated greater symptomatic improvement and a lower rate of adverse effects.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"90 1","pages":"Pages 54-62"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L.R. Valdovinos-García , A.S. Villar-Chávez , F.M. Huerta-Iga , M. Amieva-Balmori , J.S. Arenas-Martínez , R. Bernal-Reyes , E. Coss-Adame , O. Gómez-Escudero , P.C. Gómez-Castaños , M. González-Martínez , E.C. Morel-Cerda , J.M. Remes-Troche , M.C. Rodríguez-Leal , D. Ruiz-Romero , M.A. Valdovinos-Diaz , G. Vázquez-Elizondo , J.A. Velarde-Ruiz Velasco , M.R. Zavala-Solares
{"title":"Recomendaciones de buena práctica clínica en la prescripción y deprescripción de inhibidores de la bomba de protones. Revisión por expertos de la AMG","authors":"L.R. Valdovinos-García , A.S. Villar-Chávez , F.M. Huerta-Iga , M. Amieva-Balmori , J.S. Arenas-Martínez , R. Bernal-Reyes , E. Coss-Adame , O. Gómez-Escudero , P.C. Gómez-Castaños , M. González-Martínez , E.C. Morel-Cerda , J.M. Remes-Troche , M.C. Rodríguez-Leal , D. Ruiz-Romero , M.A. Valdovinos-Diaz , G. Vázquez-Elizondo , J.A. Velarde-Ruiz Velasco , M.R. Zavala-Solares","doi":"10.1016/j.rgmx.2024.11.004","DOIUrl":"10.1016/j.rgmx.2024.11.004","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Proton pump inhibitors (PPIs) are widely known drugs that are used quite frequently and indicated in both the short and long terms, in numerous acid-related diseases. Our aim was to produce an expert review that establishes recommendations for the adequate prescription and deprescription of PPIs.</div></div><div><h3>Methods</h3><div>A group of experts in PPI use that are members of the <em>Asociación Mexicana de Gastroenterología</em> (AMG), after extensively reviewing the published literature and discussing each recommendation at a face-to-face meeting, prepared the present document of good clinical practice recommendations. This document is not intended to be a clinical practice guideline or utilize the methodology said format requires.</div></div><div><h3>Results</h3><div>Eighteen experts on PPI use developed 22 good clinical practice recommendations for prescribing short-term, long-term, and on-demand PPIs, recognizing adverse events, and lastly, deprescribing PPIs, in acid-related diseases.</div></div><div><h3>Conclusions</h3><div>At present, there is scientific evidence on PPI use in numerous diseases, some in the short term (4-8 weeks), others on-demand (for short periods until symptoms improve), or in the long term (without suspending). Numerous adverse effects have been attributed to PPIs, but the majority have no well-established causal association. Nevertheless, PPIs should be suspended when there is no clear indication for their use. These recommendations aim to aid general physicians and specialists, with respect to PPI prescription and deprescription.</div><div>.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"90 1","pages":"Pages 111-130"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. García-Villarreal , L.M. Torres-Treviño , C. Herrera-Figueroa , J.O. Jáquez-Quintana , A.A. Garza-Galindo , C.A. Cortez-Hernández , D. García-Compeán , R.A. Jiménez-Castillo , H.J. Maldonado-Garza , J.A. González-González
{"title":"Un modelo tipo App que utiliza un algoritmo de regresión logística para predecir coledocolitiasis. Un ensayo clínico prospectivo","authors":"F. García-Villarreal , L.M. Torres-Treviño , C. Herrera-Figueroa , J.O. Jáquez-Quintana , A.A. Garza-Galindo , C.A. Cortez-Hernández , D. García-Compeán , R.A. Jiménez-Castillo , H.J. Maldonado-Garza , J.A. González-González","doi":"10.1016/j.rgmx.2024.05.010","DOIUrl":"10.1016/j.rgmx.2024.05.010","url":null,"abstract":"<div><h3>Introduction and objective</h3><div>The diagnostic yield of the current criteria for assigning the risk of choledocholithiasis (CL) is inaccurate. The aim of our work was to develop a logistic regression model for predicting CL diagnosis in patients catalogued as either intermediate or high risk for CL, according to the criteria of the American Society for Gastrointestinal Endoscopy (ASGE).</div></div><div><h3>Material and methods</h3><div>We conducted an analytic, observational, cross-sectional study for evaluating the diagnostic yield of a logistic regression model in adults with intermediate or high risk for CL. A receiver operating characteristic (ROC) curve analysis was done to determine the best cutoff point for predicting the diagnosis of CL. Endoscopic retrograde cholangiopancreatography (ERCP) was utilized as the gold standard for diagnosing CL.</div></div><div><h3>Results</h3><div>A total of 148 patients suspected of presenting with CL were studied. In our cohort, 71 had immediate risk and 77 had high risk. CL diagnosis was confirmed in 102 patients (69%). Our model showed an area under the curve (AUC) of 0.68. In patients with an intermediate risk for CL, the AUC value was 0.72 and the positive predictive value (PPV) was 70%. In patients with a high risk for CL, the AUC value was 0.78 and the PPV was 89%.</div></div><div><h3>Conclusion</h3><div>Our model appears to better predict the diagnosis of CL than the ASGE criteria for patients with an intermediate or high risk for the disease. Our model can guide clinical decisions in patients with suspected CL.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"90 1","pages":"Pages 22-28"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hígado II. Sesión de trabajos libres orales","authors":"","doi":"10.1016/S0375-0906(24)00181-2","DOIUrl":"10.1016/S0375-0906(24)00181-2","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"89 ","pages":"Pages 102-105"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hepatitis virales. Exposición de trabajos libres en cartel","authors":"","doi":"10.1016/S0375-0906(24)00197-6","DOIUrl":"10.1016/S0375-0906(24)00197-6","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"89 ","pages":"Pages 209-211"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neurogastroenterología IV. Sesión de trabajos libres orales","authors":"","doi":"10.1016/S0375-0906(24)00190-3","DOIUrl":"10.1016/S0375-0906(24)00190-3","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"89 ","pages":"Pages 179-182"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopia II. Sesión de trabajos libres orales","authors":"","doi":"10.1016/S0375-0906(24)00180-0","DOIUrl":"10.1016/S0375-0906(24)00180-0","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"89 ","pages":"Pages 98-101"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143168384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enfermedad inflamatoria intestinal. Sesión de trabajos libres orales","authors":"","doi":"10.1016/S0375-0906(24)00174-5","DOIUrl":"10.1016/S0375-0906(24)00174-5","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"89 ","pages":"Pages 21-25"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143169088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comités científicos","authors":"","doi":"10.1016/S0375-0906(24)00166-6","DOIUrl":"10.1016/S0375-0906(24)00166-6","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"89 ","pages":"Pages i-iii"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143130561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatría. Exposición de trabajos libres en cartel","authors":"","doi":"10.1016/S0375-0906(24)00178-2","DOIUrl":"10.1016/S0375-0906(24)00178-2","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"89 ","pages":"Pages 57-92"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143167962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}