J. Cordova-Gallardo, A.M. Vargas-Beltrán, L.A. Bastida-Castro, A. Gamboa-Domínguez, A. Gabutti-Thomas, D. Valla
{"title":"Correlación de las características clínicas y patológicas en pacientes mexicanos con enfermedad vascular portosinusoidal","authors":"J. Cordova-Gallardo, A.M. Vargas-Beltrán, L.A. Bastida-Castro, A. Gamboa-Domínguez, A. Gabutti-Thomas, D. Valla","doi":"10.1016/j.rgmx.2025.12.010","DOIUrl":"10.1016/j.rgmx.2025.12.010","url":null,"abstract":"<div><div>Porto-sinusoidal vascular disease (PSVD) is an uncommon disorder characterized by hepatic microvascular alterations and noncirrhotic portal hypertension. Its recent redefinition includes patients with and without portal hypertension, even in the presence of concomitant liver disease. The present study aimed to correlate the clinical, radiologic, and histopathologic findings in Mexican patients with PSVD and identify key diagnostic challenges.</div><div>A retrospective study was conducted on 10<!--> <!-->patients diagnosed with PSVD according to updated criteria, in whom liver biopsy showed no cirrhosis. Clinical, laboratory, imaging, and histopathologic data were collected. Upper gastrointestinal bleeding was the most frequent initial presentation, followed by mild thrombocytopenia. Biopsies revealed obliterative portal venopathy, nodular regenerative hyperplasia, and incomplete septal fibrosis. Magnetic resonance imaging identified periportal hyperintensity, which aided in differentiating PSVD from cirrhosis.</div><div>The findings confirm PSVD heterogeneity, underscoring the importance of integrating different diagnostic tools for its timely detection.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 276-281"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148572069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S.A. Chávez-Sánchez, A. Bellido-Caparó, C.A. García-Encinas, P.M. Padilla-Machaca
{"title":"Compromiso hepático como forma de presentación inicial de leucemia linfoblástica aguda de células B en adultos: serie de casos","authors":"S.A. Chávez-Sánchez, A. Bellido-Caparó, C.A. García-Encinas, P.M. Padilla-Machaca","doi":"10.1016/j.rgmx.2026.01.005","DOIUrl":"10.1016/j.rgmx.2026.01.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Hepatic involvement as an initial presentation of acute lymphoblastic leukemia (ALL) in adults is rare and may delay the diagnosis.</div></div><div><h3>Material and methods</h3><div>A case series of adult patients with confirmed B-cell ALL (B-ALL) and altered liver function tests at disease onset was conducted. Clinical, biochemical, imaging, and flow cytometry data were collected, ruling out infectious, autoimmune, and toxic etiologies.</div></div><div><h3>Results</h3><div>Three men, 68, 36, and 38 years of age, presented with cholestasis and hepatosplenomegaly with no biliary tract dilation. Flow cytometry showed high percentages of B lymphoblasts. One patient died shortly after starting chemotherapy and the other two remain on active treatment.</div></div><div><h3>Conclusion</h3><div>Hepatic infiltration due to ALL should be considered in the differential diagnosis of intrahepatic cholestasis in adults.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 282-285"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148572070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.L. Herrera-Elizondo , R.A. Jiménez-Castillo , D. García-Compeán , J.O. Jaquez-Quintana , C.A. Cortez-Hernández , C.E. González-Martínez , H.J. Maldonado-Garza , A. Garza-Galindo , J. Campos-Galván , J.A. González-González
{"title":"Metoclopramida en dosis altas versus placebo para la visualización gástrica y duodenal durante endoscopia en pacientes con sangrado agudo de tubo digestivo alto. Un ensayo clínico aleatorizado triple ciego","authors":"J.L. Herrera-Elizondo , R.A. Jiménez-Castillo , D. García-Compeán , J.O. Jaquez-Quintana , C.A. Cortez-Hernández , C.E. González-Martínez , H.J. Maldonado-Garza , A. Garza-Galindo , J. Campos-Galván , J.A. González-González","doi":"10.1016/j.rgmx.2025.10.008","DOIUrl":"10.1016/j.rgmx.2025.10.008","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>The usefulness of metoclopramide for improving endoscopic visualization in upper gastrointestinal bleeding (UGIB) is controversial. Our primary aim was to evaluate the utility of metoclopramide 20<!--> <!-->mg/IV for endoscopic visualization in UGIB of ≤ 24<!--> <!-->h. The need for a repeat endoscopy and length of hospital stay were also analyzed.</div></div><div><h3>Materials and methods</h3><div>Patients were randomized 1:1 to receive placebo (group A) or metoclopramide 20<!--> <!-->mg/IV (group B) and undergo endoscopy 30-120<!--> <!-->minutes later. Demographics, etiology, and hospital stay were evaluated. The percentage of gastroduodenal visualization was assessed through the modified Avgerinos score. A blinded, experienced endoscopist reviewed the endoscopic recordings.</div></div><div><h3>Results</h3><div>Fifty patients, 27 men and 23 women, were included. Mean patient age was 60 years, and each group was made up of 25 patients. The time from admission to endoscopy in group A was 14:21<!--> <!-->hours (SD<!--> <!-->±<!--> <!-->5.35) and 14:54<!--> <!-->hours (SD<!--> <!-->±<!--> <!-->5.83) in group B (p<!--> <!-->=<!--> <!-->0.83). The modified Avgerinos score was 7.00 (5.00-8.00) in group A and 7.00 (6.50-8.00) in group B (p<!--> <!-->=<!--> <!-->0.282). The difference in the modified Avgerinos score was not statistically significant in the patients with variceal and ulcerous etiologies (p<!--> <!-->=<!--> <!-->0.705 and p<!--> <!-->=<!--> <!-->0.721, respectively). A repeat endoscopy was required in 3 group A patients and 4 group B patients (p<!--> <!-->=<!--> <!-->0.684). Hospital stay for group A was 7.0 days (SD<!--> <!-->±<!--> <!-->3.08) and 7.32 days (SD<!--> <!-->±<!--> <!-->4.31) for group B (p<!--> <!-->=<!--> <!-->0.764).</div></div><div><h3>Conclusions</h3><div>Metoclopramide 20<!--> <!-->mg/IV before endoscopy did not improve endoscopic visualization, the need for a repeat endoscopy, or length of hospital stay in patients with UGIB.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 212-220"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factores de riesgo asociados a complicaciones tempranas en pacientes pediátricos con diagnóstico de pancreatitis aguda","authors":"C.A. González-Heredia , A.Y. Martínez-Vázquez , F.E. Hernández-Lara-González , Y. Martínez Tovilla","doi":"10.1016/j.rgmx.2025.08.001","DOIUrl":"10.1016/j.rgmx.2025.08.001","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Acute pancreatitis is a rare condition in pediatric patients, but there has been a considerable increase in cases and complications in recent years that, according to the literature, may reach up to 30% of cases. The present study aimed to determine whether the variables of sex, age group, etiology, nutritional status, lipase level, albumin level, and leukocyte count were associated with the development of early complications in pediatric patients diagnosed with acute pancreatitis.</div></div><div><h3>Materials and methods</h3><div>A retrospective study was carried out at the <em>Hospital para el Niño Poblano</em>, within the time frame of July 2014 and July 2024. The medical records of patients from 0 to 17 years 11 months of age, who met the diagnostic criteria for acute pancreatitis, were analyzed. JASP software was utilized for the statistical analysis, applying Odds Ratio (OR) to identify possible risk factors.</div></div><div><h3>Results</h3><div>A total of 143 patients were included, with a slight predominance of females (51%, n<!--> <!-->=<!--> <!-->73). Of the local complications, pancreatic necrosis was documented in 16% (n<!--> <!-->=<!--> <!-->23) and acute peripancreatic fluid collection in 12.6% (n<!--> <!-->=<!--> <!-->18). The most frequent complications were cardiac (51.75%), renal (31.47%), pulmonary (18.18%), and metabolic (16.08%).</div></div><div><h3>Conclusion</h3><div>Significant risk factors for the development of early complications in pediatric patients with acute pancreatitis were identified. These findings may support early assessment of disease severity and guide timely interventions.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 171-178"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P.M. Juárez-Villa, A.G. Valladares-Pasquel, A. Tepox-Padrón, A. Osorio-Miranda, L.G. Pedroza-Terán
{"title":"Intususcepción yeyunal secundaria a migración de catéter provisional de gastrostomía","authors":"P.M. Juárez-Villa, A.G. Valladares-Pasquel, A. Tepox-Padrón, A. Osorio-Miranda, L.G. Pedroza-Terán","doi":"10.1016/j.rgmx.2025.09.004","DOIUrl":"10.1016/j.rgmx.2025.09.004","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 268-270"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148572067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impacto en el mundo real de la inteligencia artificial en la detección de adenomas: estudio transversal en un solo centro, Lima, Perú","authors":"B. Guillen, R. Zambrano-Huailla, J.A. Chirinos","doi":"10.1016/j.rgmx.2025.09.006","DOIUrl":"10.1016/j.rgmx.2025.09.006","url":null,"abstract":"<div><h3>Introduction</h3><div>The use of artificial intelligence (AI) in endoscopic studies has grown in recent years. The present study evaluates the performance of AI in detecting polyps and adenomas in daily clinical practice.</div></div><div><h3>Materials and methods</h3><div>A cross-sectional study was conducted, in which AI-assisted colonoscopies (AIACs) performed between January 2021 and May 2024 were reviewed. Logistic regression was applied for adenoma detection, based on their characteristics.</div></div><div><h3>Results</h3><div>A total of 1,251 colonoscopies were reviewed. The patients in the AIAC group were older than the control group (59<!--> <!-->±<!--> <!-->13 vs. 56<!--> <!-->±<!--> <!-->12 years, <em>P</em><.05). There were no differences between sex, procedure indication, bowel preparation, and procedure time. Regarding the primary aim, the AIAC group had a significantly higher polyp detection rate (58 vs. 52%; <em>P</em><.05) and non-significantly higher adenoma detection rate (39 vs. 33%; <em>P</em>>.05), compared with the control group. In the analysis of adenoma characteristics, the identification of polypoid adenomas (OR: 1.28; 95% CI: 1.04-1.59), smaller 10<!--> <!-->mm (OR: 1.41; 95% CI: 1.14-1.74), and located in the proximal colon (OR: 1.31; 95% CI: 1.05-1.65) was significantly higher in the AIAC group, compared with the control group.</div></div><div><h3>Conclusions</h3><div>The use of AI in colonoscopies resulted in a non-significant increase in the adenoma detection rate but a significant increase in detecting polypoid adenomas smaller than 10<!--> <!-->mm and located in the proximal colon.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 200-206"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148572045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Zayas-Bórquez, C.Z. Diaz-Barrientos, J. Canto-Losa, N. Salgado-Nesme, O. Santes-Jasso
{"title":"¿Qué factores prolongan los síntomas en pacientes con enfermedad hemorroidal que requieren cirugía?","authors":"R. Zayas-Bórquez, C.Z. Diaz-Barrientos, J. Canto-Losa, N. Salgado-Nesme, O. Santes-Jasso","doi":"10.1016/j.rgmx.2025.09.009","DOIUrl":"10.1016/j.rgmx.2025.09.009","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Hemorrhoidal disease is a common condition and may affect quality of life. Although it tends to respond to conservative treatment, some cases require surgery. The present study examined clinical and demographic factors associated with symptom duration in surgically treated patients, with no causal inference or predictive intent.</div></div><div><h3>Materials and methods</h3><div>A retrospective, cross-sectional study was conducted at the <em>Hospital Universitario de Puebla</em> on 56 patients who underwent hemorrhoidectomy (2019-2023). The factors of sex, age, smoking, constipation, BMI, and time to surgery were analyzed, employing descriptive statistics, linear regression, and K-Fold cross-validation.</div></div><div><h3>Results</h3><div>There was a significant association between sex and years of disease (p<!--> <!-->=<!--> <!-->0.0427), with men having a mean 4.89 more years of disease than women (β<!--> <!-->=<!--> <!-->–4.89, 95% CI –9.61 to –0.17). There was a positive, non-significant association between age and years of disease (p<!--> <!-->=<!--> <!-->0.0907). A significant inverse relation was identified between age at disease onset and years of disease (p <<!--> <!-->0.001; β<!--> <!-->=<!--> <!-->–0.31, 95% CI –0.46 to –0.15), as well as a significant interaction between sex and age at onset (p <<!--> <!-->0.001).</div></div><div><h3>Conclusions</h3><div>Sex and age at disease onset were key factors associated with symptom duration in patients who underwent hemorrhoidectomy. Factors traditionally considered relevant, such as constipation and BMI, showed no significant association, highlighting the importance of considering complex interactions between clinical and demographic variables.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 207-211"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148572046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Hernández-Rosiles, A. Carias-Domínguez, G. Baules de Arrocha, J.F. Garcés-Camacho, M. Fisberg, M.C. Bages-Mesa, M. Higuera-Carillo, W. Daza-Carreño, J. Ho, M. Alfaro-Hurtado, C.L. Taquez-Castro, V. Silva-Weffort, M.S. Peredo, S. Peña-Hernández, M.C. Sanabria, L. Escobedo-Berumen, L. Ladino, S. Sanjuanelo-Camargo, A.M. Pazmiño, A. Zambrano-Rivas, R. Vázquez-Frias
{"title":"Dificultades alimentarias en la infancia: revisión narrativa y propuesta de abordaje interdisciplinario","authors":"V. Hernández-Rosiles, A. Carias-Domínguez, G. Baules de Arrocha, J.F. Garcés-Camacho, M. Fisberg, M.C. Bages-Mesa, M. Higuera-Carillo, W. Daza-Carreño, J. Ho, M. Alfaro-Hurtado, C.L. Taquez-Castro, V. Silva-Weffort, M.S. Peredo, S. Peña-Hernández, M.C. Sanabria, L. Escobedo-Berumen, L. Ladino, S. Sanjuanelo-Camargo, A.M. Pazmiño, A. Zambrano-Rivas, R. Vázquez-Frias","doi":"10.1016/j.rgmx.2026.03.002","DOIUrl":"10.1016/j.rgmx.2026.03.002","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Feeding difficulties (FDs) in childhood are highly prevalent and a common reason for medical consultation. Historically, clinical approaches have been fragmented. The Pediatric Feeding Disorder (PFD) model provides a comprehensive framework that incorporates medical, nutritional, feeding skill, and psychosocial dimensions. Our aims were to: 1) describe the current definitions of FDs in children, 2) identify their main risk factors and existing classifications, and 3) propose a clinical algorithm to guide the diagnostic and therapeutic approach from an interdisciplinary perspective.</div></div><div><h3>Materials and methods</h3><div>A narrative review was carried out by the Feeding Difficulties Working Group of the Latin American Society of Pediatric Gastroenterology, Hepatology and Nutrition (LASPGHAN), reviewing the literature published between January 2000 and April 2025 from the PubMed, Scopus, SciELO, and LILACS databases.</div></div><div><h3>Results</h3><div>Three classification systems were identified: sensory-based, medical/nutritional, and functional. Risk factors included prematurity, gastrointestinal and neuromotor diseases, negative feeding experiences, inadequate feeding practices, and psychosocial factors. A comprehensive and interdisciplinary clinical algorithm was developed.</div></div><div><h3>Conclusions</h3><div>Pediatric FDs require an interdisciplinary and family-centered approach, adapted to the Latin American context. Terminology standardization and clinical criteria harmonization are key steps for optimizing diagnosis, treatment, and research in the region. The development of a clinical algorithm outlining their approach is a first step toward this goal.</div></div>","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 221-230"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148572047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hemangioendotelioma esplénico en una mujer menopáusica","authors":"G.S.A. Alegre-Salles , V.J. Alegre-Salles","doi":"10.1016/j.rgmx.2026.01.009","DOIUrl":"10.1016/j.rgmx.2026.01.009","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 260-261"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148388967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.A. Valdovinos-Díaz , A. Lopez-Colombo , M.J. Schmulson-Wasserman
{"title":"Rebamipida como tratamiento adyuvante en los esquemas de erradicación de Helicobacter pylori","authors":"M.A. Valdovinos-Díaz , A. Lopez-Colombo , M.J. Schmulson-Wasserman","doi":"10.1016/j.rgmx.2025.12.005","DOIUrl":"10.1016/j.rgmx.2025.12.005","url":null,"abstract":"","PeriodicalId":51767,"journal":{"name":"Revista de Gastroenterologia de Mexico","volume":"91 2","pages":"Pages 286-287"},"PeriodicalIF":2.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148388977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}