Journal of Clinical and Health Sciences最新文献

A Case of Spinal Muscular Atrophy Type 2 in a Child: A Genetic Condition Rarely Detected in Primary Care 一例脊髓肌肉萎缩症 2 型患儿：基层医疗机构罕见的遗传病

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.25790

S. M. Abu Hussain, N. A. Shibraumalisi, H. N. Miptah, Anis Safura Ramli

{"title":"A Case of Spinal Muscular Atrophy Type 2 in a Child: A Genetic Condition Rarely Detected in Primary Care","authors":"S. M. Abu Hussain, N. A. Shibraumalisi, H. N. Miptah, Anis Safura Ramli","doi":"10.24191/jchs.v9i1.25790","DOIUrl":"https://doi.org/10.24191/jchs.v9i1.25790","url":null,"abstract":"Spinal muscular atrophy (SMA) is a neurodegenerative disease affecting 4 out of 10,000 live births. It is an autosomal recessive genetic condition caused by mutations of the survival motor neuron gene 1 (SMN1), located at chromosome 5q. There are five types of SMA, from Type 0 to Type 4. Depending on the types, SMA can cause severe disability and death. This case report presents a case of a six-month old baby boy with gross motor developmental regression. There was a missed opportunity to detect this case in primary care. The baby was referred by a private paediatrician to a government hospital’s outpatient paediatric clinic for losing his ability to roll over, lift his buttocks, and sit without support. Genetic testing confirmed the diagnosis of SMA Type 2. Receiving the diagnosis and caring for a child with SMA is a life-changing event for the parents and caregivers. The availability of gene therapy may change the prognosis and outcome of patients with SMA and should be offered if available. This case highlights the impact of the child’s illness on the family and the importance of a multidisciplinary team approach in managing SMA. Primary care physicians play a key role in conducting thorough child health surveillance to ensure early identification and providing support to the child and the parents holistically as the disease progresses into adulthood. This includes providing long-term psychosocial support to improve their quality of life.","PeriodicalId":517565,"journal":{"name":"Journal of Clinical and Health Sciences","volume":"49 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140400585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, Awareness and Perception of Human Papillomavirus Testing Among Staff in a Public University in Malaysia 马来西亚公立大学教职员工对人类乳头瘤病毒检测的了解、认识和看法

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.21044

Amanda C Yun-Vern, Nor Fadlina Mazlan, Muhammad Haziq Nizaruddin, Rima Dasrilsyah

{"title":"Knowledge, Awareness and Perception of Human Papillomavirus Testing Among Staff in a Public University in Malaysia","authors":"Amanda C Yun-Vern, Nor Fadlina Mazlan, Muhammad Haziq Nizaruddin, Rima Dasrilsyah","doi":"10.24191/jchs.v9i1.21044","DOIUrl":"https://doi.org/10.24191/jchs.v9i1.21044","url":null,"abstract":"Introduction: HPV testing has been introduced in Malaysia for nearly 10 years. However, the Malaysian population are largely unaware of its availability and significance in the prevention of cervical cancer. Due to this fact, this study aims to determine the knowledge, awareness and perception of HPV testing and association with sociodemographic characteristics among a university staff, a study sample derived from the community in the state of Selangor, Malaysia. Methods: A cross-sectional study was conducted among University Putra Malaysia (UPM) staff from various faculties. Recruitment of study subjects was done through convenient sampling. Data on knowledge, awareness, and perception of HPV testing, alongside with socio-demographic factors were collected using online questionnaires. Statistical analyses were performed using IBM Statistical Package for Social Science (SPSS) version 26.0. Results: A total of 166 respondents participated in the study. Gender (female) and ethnicity (Chinese) were associated with higher level of knowledge on HPV testing. Meanwhile, females outperformed males in terms of awareness of the test. Other sociodemographic characteristics have no significant association with perception of HPV testing. Conclusion: This study indicated that the level of knowledge on HPV testing was generally poor, especially among Malays and other minority races. Awareness was also lower mostly among male respondents. Our findings highlighted the importance of improving the level of awareness and knowledge of HPV testing, to reduce the prevalence of HPV-related morbidity and mortality in Malaysia.","PeriodicalId":517565,"journal":{"name":"Journal of Clinical and Health Sciences","volume":"45 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140400876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synergetic Effect of Electroconvulsive Therapy and Clozapine therapy in Treating Severe Intractable Aggressive Behaviour in an Adult with Intellectual Disability: A Case Report 电休克疗法和氯氮平疗法在治疗一名智障成人的严重顽固攻击行为中的协同效应：病例报告

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.16512

S. Ariaratnam, Wei Son Da, Muhammad Adib Baharom

引用次数: 0

The Utility Of 1-Minute Sit-To-Stand Test to Detect Exercise-Induced Oxygen Desaturation in Outpatient Assessment of Post COVID-19 Patients 在门诊评估 COVID-19 后患者时，1 分钟坐立测试对检测运动诱发的氧饱和度的实用性

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.21407

Muhammad Amin Ibrahim, Chee Chai Shee, Mohd Nazeri Kamarudin, M. F. A. Abdul Rani

{"title":"The Utility Of 1-Minute Sit-To-Stand Test to Detect Exercise-Induced Oxygen Desaturation in Outpatient Assessment of Post COVID-19 Patients","authors":"Muhammad Amin Ibrahim, Chee Chai Shee, Mohd Nazeri Kamarudin, M. F. A. Abdul Rani","doi":"10.24191/jchs.v9i1.21407","DOIUrl":"https://doi.org/10.24191/jchs.v9i1.21407","url":null,"abstract":"Introduction: 6-min-walk-test (6MWT) is the gold standard for assessing exercise-induced impairment of gas exchange, but it is technically challenging in a busy outpatient clinic. The aim of this study was to compare the 1-minute sit-to-stand test (1MSTST) with the 6MWT in assessment of exercise-induced oxygen desaturation in post COVID-19 patients in an outpatient setting. Methods: A total of 447 outpatient post COVID-19 patients were recruited from post COVID-19 clinic. A set of 6MWT and 1MSTST were performed on the same day. Results: A total of 447 sets were performed at a mean of 160 days post discharge. Majority were in COVID-19 infection category 4 (n=251, 56%), 5 (n=118, 26%) and 3 (n=6, 15%). A total of 19% (n=89) of patients remained symptomatic (mMRC >1). There were no significant differences between nadir SpO2 of 6MWT and 1STST (p=0.075). Bland-Altman plots showed good agreement between nadir SpO2 for 6MWT and 1MSTST (Mean differences=0.028). 1MSTST could detect oxygen desaturation >4% with sensitivity of 76.8% and specificity of 42.4% compared to 6MWT. There was no clinically significant SpO2 difference during 6MWT and 1STS between symptomatic and asymptomatic patients at baseline, nadir, and recovery; the differences were <1%. However, there were lesser 6MWT distance and 1MSTST repetition between symptomatic and asymptomatic patients; 47m (p < 0.001) and 3 repetition (p < 0.001) respectively. Conclusion: There is a good agreement of nadir SpO2 and sensitivity to detect oxygen desaturation > 4% between 6MWT and 1MSTST. 1MSTST is a useful screening test to screen exercise-induced oxygen desaturation during outpatient assessment.","PeriodicalId":517565,"journal":{"name":"Journal of Clinical and Health Sciences","volume":"8 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140404449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proceeding of International Conference on Precision Health in Industrial Revolution 4.0 (IC-PHIR), 26-27th August 2023 (pS1-S28) 工业革命 4.0 中的精准健康国际会议（IC-PHIR）论文集，2023 年 8 月 26-27 日（pS1-S28）

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1(s).25791

引用次数: 0

COVID-19 Booster Vaccination in Malaysia 马来西亚的 COVID-19 强化疫苗接种

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.19570

Nor Elyzatul Akma Hamdan, Ali Omar Yassen, Mathumalar Loganathan Fahrni

{"title":"COVID-19 Booster Vaccination in Malaysia","authors":"Nor Elyzatul Akma Hamdan, Ali Omar Yassen, Mathumalar Loganathan Fahrni","doi":"10.24191/jchs.v9i1.19570","DOIUrl":"https://doi.org/10.24191/jchs.v9i1.19570","url":null,"abstract":"After battling the extreme acute respiratory syndrome-causing coronavirus disease 2019 (COVID-19) pandemic for more than two years, the vaccines have enabled the transition to endemicity. Despite vaccine advancement, Mankind will be one step behind viruses like SARS-CoV-2 as the latter continuously evolve into variants with higher transmissibility. They demonstrate immune escape through genetic mutation or viral recombination which occurs during replication of the genome. Vaccine variants in the form of booster doses are required following the initial vaccination series to prevent the spread of the more dangerous SARS-CoV-2 variants of concern (VoC) such as Omicron. Protection against COVID-19 for those with chronic comorbid conditions, those who are immunosuppressed, and vulnerable, at-risk population was postulated to decline rapidly with time from their last vaccination. As the elicited adaptive immune response declines, older adults and at-risk populations continue to be at the highest risk of morbidity and mortality from future VoC. Current vaccines are effective at reducing severe respiratory-related illnesses, hospitalisation, and mortality attributed to COVID-19, yet cannot fully protect against developing an infection. The article summarises the evidence and policy recommendations for COVID-19 booster shots. This information is useful for future planning by policymakers and healthcare providers to make vaccination policies and decisions, particularly for including the COVID-19 vaccines in national immunization programs.","PeriodicalId":517565,"journal":{"name":"Journal of Clinical and Health Sciences","volume":"172 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140404825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urban and Suburban COVID-19 Immunization: Comparison of Experiences at Parit Sulong and Puncak Alam 城市和郊区 COVID-19 免疫接种：Parit Sulong 和 Puncak Alam 的经验比较

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.20471

Mawaddah Azman, Hardip Singh Gendeh, Wan Najwa Wan Mohd Zobdi, Juliana Md Noor, R. Jarmin, Hanafiah Harunarashid

{"title":"Urban and Suburban COVID-19 Immunization: Comparison of Experiences at Parit Sulong and Puncak Alam","authors":"Mawaddah Azman, Hardip Singh Gendeh, Wan Najwa Wan Mohd Zobdi, Juliana Md Noor, R. Jarmin, Hanafiah Harunarashid","doi":"10.24191/jchs.v9i1.20471","DOIUrl":"https://doi.org/10.24191/jchs.v9i1.20471","url":null,"abstract":"Introduction: Malaysia boasts a diverse geographical distribution ranging from urban, suburban and rural areas. The COVID-19 national immunization program calls for specific strategies to enhance vaccine roll-out. Methods: A retrospective study was conducted at two vaccination centres in Parit Sulong and Puncak Alam. Registration data from 150 and 1420 consenting adults receiving their first dose of COVID-19 vaccination from Parit Sulong and Puncak Alam were included, respectively. Results: The vaccination center at Parit Sulong utilised three methods: 1) satellite vaccination camp; 2) mobile outreach camp; and 3) home-to-home visits to improve vaccine reach in a rural district. The vaccination center at Puncak Alam utilised two methods: 1) vaccination in a large hall; and 2) drive-through vaccination to enhance daily vaccine administration in an urban district. The vaccine recipients at Parit Sulong were significantly older compared to Puncak Alam (70.39 SD 11.39 vs 51.52 SD 11.02 years) (p<0.0001). A significantly higher proportion of vaccine recipients at Parit Sulong were unable to read or write in their mother tongue (41.33%)(p<0.0001), do not own a mobile phone (53.33%)(p<0.0001) and do not have access to MySejahtera mobile application(84.57%)(p<0.0001). Conclusion: The mobile vaccination model allows for greater vaccination reach and administration, targeting suburban and rural residents with transportation and technology restrictions. The drive-through vaccination model improved the vaccine uptake among young families with children, heavily pregnant ladies and elderly with physical limitations living in urban areas who have access to MySejahtera.","PeriodicalId":517565,"journal":{"name":"Journal of Clinical and Health Sciences","volume":"104 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140405699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Papillary Carcinoma of Thyroglossal Duct Cyst with a Normal Thyroid Gland Appearance: A Case Report 甲状腺外观正常的甲状舌管囊肿乳头状癌：病例报告

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.13663

Wan Ahmad Amiruddin Wan Hassan, Wan Islah Leman, Khairul Azhar M. Rajet, Mohd Najeb Md Soleh

引用次数: 0

My child has a hard mass over the thigh 我的孩子大腿上有硬块

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.15824

Shahrul-Hisham Sulaiman

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Valentino’s Syndrome: The Red Herring of a Perforated Viscus 瓦伦蒂诺综合征内脏穿孔的红鲱鱼

Journal of Clinical and Health Sciences Pub Date : 2024-03-01 DOI: 10.24191/jchs.v9i1.14680

Shaiful Amir Abdul Manap, Rabi’atul Adawiyah Ahmad, Hazzeq Safin Hashim

引用次数: 0