Journal of Medical Physics最新文献_第5页

Multifaceted Characterization and Therapeutic Evaluation of Co-precipitated Cobalt Ferrite Nanoparticles for Magnetic Hyperthermia Cancer Therapy. 磁性热疗癌症的共沉淀钴铁氧体纳米颗粒的多方面表征和治疗评价。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_57_24

R Jafrin Reena, N Arunai Nambi Raj

{"title":"Multifaceted Characterization and Therapeutic Evaluation of Co-precipitated Cobalt Ferrite Nanoparticles for Magnetic Hyperthermia Cancer Therapy.","authors":"R Jafrin Reena, N Arunai Nambi Raj","doi":"10.4103/jmp.jmp_57_24","DOIUrl":"10.4103/jmp.jmp_57_24","url":null,"abstract":"Aim: Magnetic-mediated hyperthermia has emerged as a promising therapeutic approach for treating cancer. This technique employs the heat dissipated by the magnetic nanoparticles when subjected to an external varying magnetic field, to bring about localized hyperthermia in tumor tissues. Owing to their conducive and tuneable \"physical, chemical, and magnetic\" characteristics, cobalt ferrite (CoFe2O4) nanoparticles are recognized as emerging contenders. The aim of the present work was to enhance the magnetic characteristics and guarantee the efficacy of CoFe2 O4 nanoparticles in targeting and eliminating cancer cells.Methods: CoFe2O4 nanoparticles were synthesized using the chemical co-precipitation route and underwent rigorous structural, morphological, and magnetic characterization techniques. The synthesized particles were then subjected to in vitro studies to evaluate their cytotoxicity and antimicrobial susceptibility.Results: The characterization techniques confirmed the cubic structure, ferrite phase, and spherical and magnetic nature of CoFe2O4 nanoparticles. The zeta potential was found to be - 0.0048V (4.8 mV). Cytotoxicity analysis exhibited decreased cell viability with increasing concentrations of CoFe2O4 nanoparticles. Antimicrobial studies displayed good inhibiting properties.Conclusion: The zeta potential of the synthesized CoFe2O4 nanoparticles was found to be higher than that of the breast cancer cells (MCF-7) which proves the synthesized drug to be effective. The in vitro studies also disclose the efficacy of the drug over cancer cells.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"510-518"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study. 用18 MV医用直线加速器定量评估光子诱导前列腺二次辐射剂量：蒙特卡罗研究

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_141_24

Mustapha Assalmi, Abdullah Alshreef, El Yamani Diaf, Assia Arectout, Nicholas Ade, El Hassan El Berhdadi

{"title":"Quantitative Assessment of Photoneutron-induced Secondary Radiation Dose in Prostate Treatment Using an 18 MV Medical Linear Accelerator: A Monte Carlo Study.","authors":"Mustapha Assalmi, Abdullah Alshreef, El Yamani Diaf, Assia Arectout, Nicholas Ade, El Hassan El Berhdadi","doi":"10.4103/jmp.jmp_141_24","DOIUrl":"10.4103/jmp.jmp_141_24","url":null,"abstract":"Purpose: This study aims to quantify the secondary radiation dose caused by photoneutrons during prostate cancer treatment using an 18 MV medical linear accelerator (LINAC) through Monte Carlo simulations and experimental validation.Methods: Monte Carlo simulations were performed using G4Linac_MT to model the 18 MV photon beam of an Elekta LINAC. The simulation results were validated against experimental measurements. Neutron characteristics, including penetration, cross-section interactions, Linear Energy Transfer (LET), and dose contributions, were analyzed using an adult male ICRP phantom. Prostate treatment scenarios involved 3D-CRT plans with 4-fields, 5-fields, and 7-fields. Specific absorbed fractions (SAFs) in various organs were also evaluated.Results: Simulation and experimental measurements showed strong agreement, with a dose error of approximately 0.74%, and 97% of dose points passed a 2%/2 mm gamma index. Intermediate neutrons constituted 87.05%, while 12.95% were fast neutrons. Neutron dose contributions were 0.63%, 0.33%, and 0.77% for the 3D-CRT 4-field, 5-field, and 7-field plans, respectively. SAF values decreased as neutron energy increased, highlighting reduced neutron interaction efficiency at higher energies.Conclusions: Monte Carlo simulation is a reliable approach for evaluating neutron dose contributions in high-energy X-ray LINACs. Optimization of treatment plans is essential to minimize neutron-induced dose contributions.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"673-686"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial Neural Network-based Model for Predicting Cardiologists' Over-apron Dose in CATHLABs. 基于人工神经网络的CATHLABs心脏科医师过围裙剂量预测模型。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-10-30 DOI: 10.4103/jmp.jmp_99_24

Reza Fardid, Fatemeh Farah, Hossein Parsaei, Hadi Rezaei, Mohammad Vahid Jorat

{"title":"Artificial Neural Network-based Model for Predicting Cardiologists' Over-apron Dose in CATHLABs.","authors":"Reza Fardid, Fatemeh Farah, Hossein Parsaei, Hadi Rezaei, Mohammad Vahid Jorat","doi":"10.4103/jmp.jmp_99_24","DOIUrl":"10.4103/jmp.jmp_99_24","url":null,"abstract":"Aim: The radiation dose that cardiologists receive in the catheterization laboratory is influenced by various factors. Handling high-stress tasks in interventional cardiology departments may cause physicians to overlook the use of dosimeters. Therefore, it is essential to develop a model for predicting cardiologists' radiation exposure.Materials and methods: This study developed an artificial neural network (ANN) model to predict the over-apron radiation dose received by cardiologists during catheterization procedures, using dose area product (DAP) values. Leveraging a validated Monte Carlo simulation program, we generated data from simulations with varying spectra (70, 81, and 90 kVp) and tube orientations, resulting in 125 unique scenarios. We then used these data to train a multilayer perceptron neural network with four input features: DAP, energy spectrum, tube angulation, and the resulting cardiologist's dose.Results: The model demonstrated high predictive accuracy with a correlation coefficient (R-value) of 0.95 and a root mean square error (RMSE) of 3.68 µSv, outperforming a traditional linear regression model, which had an R-value of 0.48 and an RMSE of 18.15 µSv. This significant improvement highlights the effectiveness of advanced techniques such as ANNs in accurately predicting occupational radiation doses.Conclusion: This study underscores the potential of ANN models for accurate radiation dose prediction, enhancing safety protocols, and providing a reliable tool for real-time exposure assessment in clinical settings. Future research should focus on broader validation and integration into real-time monitoring systems.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"623-630"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Elite Version of Telecobalt Machine with O-ring Design for Clinical Radiation Therapy. 一种用于临床放射治疗的o型环设计的远程钴机。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_164_24

Ramamoorthy Ravichandran, G V Subrahmanyam

引用次数: 0

Comparative Study of Fluence Distribution and Point Dose Using Arc-check and Delta⁴ Phantoms. 弧检和delta - 4幻影的通量分布和点剂量比较研究。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_130_24

Sandeep Singh, Manindra Bhushan, Benoy Kumar Singh, Anuj Kumar, Dipesh, Abhay Kumar Singh, Munish Gairola, Vikram

{"title":"Comparative Study of Fluence Distribution and Point Dose Using Arc-check and Delta4 Phantoms.","authors":"Sandeep Singh, Manindra Bhushan, Benoy Kumar Singh, Anuj Kumar, Dipesh, Abhay Kumar Singh, Munish Gairola, Vikram","doi":"10.4103/jmp.jmp_130_24","DOIUrl":"10.4103/jmp.jmp_130_24","url":null,"abstract":"The study aims to assess the fluence distribution and point dosage between two phantoms for patient-specific quality assurance on the Tomotherapy system. This was a retrospective study conducted on 15 patients who had radiation using the Helical Tomotherapy Machine (Radixact, Accuray Inc.). We used two phantoms to quantify the fluence produced by the treatment planning system (TPS) and recorded from the machine. The ArcCHECK (Sun-Nuclear) has 1386 diodes placed in a cylindrical configuration. The minimal resolution for this was 7 mm. The second was Delta4, supplied by ScandiDos. It has 1069 diode detectors arrayed in a crossed orthogonal configuration with a minimum resolution of 5 mm. All patient plans were transferred to these phantoms to validate the accuracy of treatment plan delivery. We used SunCHECK and ScandiDos Delta4 software to compare the fluence produced by the TPS with the fluence measured by the equipment. In ArcCHECK, we used an external ionization chamber, cc13 (IBA dosimetry), whereas in Delta4,we employed a central diode detector to quantify point dosage. The mean and standard deviation of the gamma pass percentage with ArcCHECK were 98.3 ± 0.8%, with an average point dose deviation of ± 0.94%. The mean and standard deviation of the gamma pass percentage using Delta4 was 99.1 ± 1.6%, while the average point dose deviation was ± 0.60%, both of which were well within the 3% tolerance employing the two phantoms.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"706-709"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the Impact of Voxel Size and Postfiltering on Quantitative Analysis of Positron Emission Tomography/Computed Tomography: A Phantom Study. 研究体素大小和后滤波对正电子发射断层扫描/计算机断层扫描定量分析的影响：一项幻影研究。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_123_24

Ahmed Abdel Mohymen, Hamed Ibrahim Farag, Sameh M Reda, Ahmed Soltan Monem, Said A Ali

{"title":"Investigating the Impact of Voxel Size and Postfiltering on Quantitative Analysis of Positron Emission Tomography/Computed Tomography: A Phantom Study.","authors":"Ahmed Abdel Mohymen, Hamed Ibrahim Farag, Sameh M Reda, Ahmed Soltan Monem, Said A Ali","doi":"10.4103/jmp.jmp_123_24","DOIUrl":"10.4103/jmp.jmp_123_24","url":null,"abstract":"Aim: This study aims to investigate the influence of voxel size and postfiltering on the quantification of standardized uptake value (SUV) in positron emission tomography/computed tomography (PET/CT) images.Materials and methods: National Electrical Manufacturers Association phantom with the spheres of different sizes were utilized to simulate the lesions. The phantom was scanned using a PET/CT scanner, and the acquired images were reconstructed using two different matrix sizes, (192 × 192) and (256 × 256), and a wide range of postfiltering values.Results: The findings demonstrated that postfiltering significantly affected SUV measurements. The changes in postfiltering values can result in overestimation or underestimation of SUV values, highlighting the importance of carefully selecting appropriate filters. Increasing the matrix size improved SUVmax and SUVmean values, particularly for small-sized spheres. Smaller voxel reconstructions slightly reduced partial volume effects and partially enhanced SUV quantification.Conclusions: Careful consideration of postfiltering values and matrix size selection can lead to better SUV quantification. These findings emphasize the need to optimize the reconstruction parameters to enhance the clinical utility of PET/CT in detecting and evaluating malignant lesions.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"597-607"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Effect of Calibration Curves Obtained from Different Computed Tomography Devices on the Dose Distribution of Tomotherapy Plans. 不同ct设备标定曲线对断层治疗方案剂量分布影响的研究。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_129_24

Hikmettin Demir, Osman Vefa Gül, Gül Kanyilmaz

{"title":"Investigation of the Effect of Calibration Curves Obtained from Different Computed Tomography Devices on the Dose Distribution of Tomotherapy Plans.","authors":"Hikmettin Demir, Osman Vefa Gül, Gül Kanyilmaz","doi":"10.4103/jmp.jmp_129_24","DOIUrl":"10.4103/jmp.jmp_129_24","url":null,"abstract":"Purpose: This study investigated the effect of Hounsfield units (HU)-relative electron density (RED) calibration curves obtained with devices from three different Computed Tomography (CT) manufacturers on dose distribution in Accuray Precision planning of patients with lung cancer.Methods: All CT data required for treatment planning system (TPS) were obtained using the Tomotherapy \"cheese\" phantom. HU RED calibration curves were created with images obtained from Siemens Somatom, GE Optima, and Toshiba Aquilion devices. The obtained calibration curve was extrapolated. CT images of lung cancer patients were acquired on a single device and treatment plans were created. The existing plans were recalculated using three calibration curves and the effect of the HU RED calibration curve on dose distribution was analyzed.Results: The results showed that different CTs did not produce significant dose differences in organ doses and PTV for Accuray TPS.Conclusions: Based on clinical judgment, images from different CT devices can be used in treatment planning.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"545-550"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Molecular Interactions, Optical, and Structural Properties through the Green Synthesis of Selenium Oxide Nanoparticles from Hibiscus sabdarriffal: Biocompatibility for Biophysics. 绿色合成木槿氧化硒纳米粒子的分子相互作用、光学和结构特性研究：生物物理学的生物相容性。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_144_24

Ali Bahari, Saad I Esmail, Ashraf M Alattar

{"title":"Study of Molecular Interactions, Optical, and Structural Properties through the Green Synthesis of Selenium Oxide Nanoparticles from Hibiscus sabdarriffal: Biocompatibility for Biophysics.","authors":"Ali Bahari, Saad I Esmail, Ashraf M Alattar","doi":"10.4103/jmp.jmp_144_24","DOIUrl":"10.4103/jmp.jmp_144_24","url":null,"abstract":"Background: Recently, the green synthesis process has been utilized to manufacture a large quantity of metal nanocrystallites due to its low cost and the availability of numerous natural resources and the find the activity of bacteria and viruses that in the body of humans.Aims and objectives: In this study, nanocrystallites of selenium oxide were produced utilizing Hibiscus sabdariffa. Researchers have analyzed the antibacterial properties and nanostructure characteristics of selenium oxide nanocrystallites using various techniques methods, such as imaging microscopy, scanning electron microscopy, ultraviolet‒visible spectroscopy (UV‒VIS), transmission electron microscopy, atomic force microscopy, and X-ray diffraction (XRD) spectroscopy.Results: According to the results, the films are discovered to have a nanocrystalline structure in a cubic spinel configuration. The crystallites are semispherical in shape and are both uniform and easily distributed. The XRD data were recorded on card number 22-1314, and the 2 θ (hkl) value was 38.351 (311). The UV‒VIS spectrum of the material exhibited a plasmon resonance peak at 272 nm, confirming the presence here of selenium oxide. This study also investigated the response of four distinct strains of pathogenic bacteria to biosynthesized selenium oxide nanoparticles (NPs). The data indicate that the biosynthesized selenium oxide NPs were highly effective against Klebsiella spp. and had the lowest effectiveness against Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli.Conclusions: The utilization of selenium oxide nanocrystals as antibacterial agents has yielded diverse outcomes, demonstrating their remarkable efficacy in combatting Klebsiella spp.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"557-562"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Simulation Study for Optimal Pinhole Collimator Design in Gamma Camera Systems. 伽玛相机系统针孔准直器优化设计的仿真研究。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_127_24

M A Ghoneim

{"title":"A Simulation Study for Optimal Pinhole Collimator Design in Gamma Camera Systems.","authors":"M A Ghoneim","doi":"10.4103/jmp.jmp_127_24","DOIUrl":"10.4103/jmp.jmp_127_24","url":null,"abstract":"Background: The usage of a semiconductor detector with a pinhole collimator can provide high spatial resolution due to its high intrinsic resolution. However, the collimator system has low sensitivity due to the hole's small diameter. Therefore, the optimization between the spatial resolution and sensitivity is critical for determining the image quality in the gamma camera system.Aims and objectives: A pinhole collimator was designed and simulated to achieve the desired level of resolution and sensitivity in a gamma camera by utilizing a CdTe semiconductor detector.Materials and methods: To conduct this objective, a simulation toolkit based on the Geant4 Application for Tomographic Emission (GATE) was employed. The imaging capabilities of the proposed system were assessed by varying the magnification factor and pinhole diameter to estimate spatial resolution and sensitivity. Moreover, a hot rod phantom was designed to evaluate the system's overall imaging functionality.Results: Results revealed that an increase in the pinhole diameter was correlated with an increase in sensitivity, while the spatial resolution was decreasing. There were distinct variations in sensitivity and spatial resolution depending on changes in the magnification factor as well. Finally, by analyzing trade-off curves, 1.38±0.081 mm was approximately the optimal pinhole diameter for our proposed system.Conclusion: The optimum position for a pinhole collimator with a CdTe semiconductor detector was demonstrated.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"648-653"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and Validation of Cloud-based Heart Rate Variability Monitor. 基于云的心率变异性监测仪的开发与验证。

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Journal of Medical Physics Pub Date : 2024-10-01 Epub Date: 2024-12-18 DOI: 10.4103/jmp.jmp_151_24

Sushma N Bhat, Ghanshyam D Jindal, Gajanan D Nagare

{"title":"Development and Validation of Cloud-based Heart Rate Variability Monitor.","authors":"Sushma N Bhat, Ghanshyam D Jindal, Gajanan D Nagare","doi":"10.4103/jmp.jmp_151_24","DOIUrl":"10.4103/jmp.jmp_151_24","url":null,"abstract":"Context: This article introduces a new cloud-based point-of-care system to monitor heart rate variability (HRV).Aims: Medical investigations carried out at dispensaries or hospitals impose substantial physiological and psychological stress (white coat effect), disrupting cardiovascular homeostasis, which can be taken care by point-of-care cloud computing system to facilitate secure patient monitoring.Settings and design: The device employs MAX30102 sensor to collect peripheral pulse signal using photoplethysmography technique. The non-invasive design ensures patient compliance while delivering critical insights into Autonomic Nervous System activity. Preliminary validations indicate the system's potential to enhance clinical outcomes by supporting timely, data-driven therapeutic adjustments based on HRV metrics.Subjects and methods: This article explores the system's development, functionality, and reliability. System designed is validated with peripheral pulse analyzer (PPA), a research product of electronics division, Bhabha Atomic Research Centre.Statistical analysis used: The output of developed HRV monitor (HRVM) is compared using Pearson's correlation and Mann-Whitney U-test with output of PPA. Peak positions and spectrum values are validated using Pearson's correlation, mean error, standard deviation (SD) of error, and range of error. HRV parameters such as total power, mean, peak amplitude, and power in very low frequency, low frequency, and high frequency bands are validated using Mann-Whitney U-test.Results: Pearson's correlation for spectrum values has been found to be more than 0.97 in all the subjects. Mean error, SD of error, and range of error are found to be in acceptable range.Conclusions: Statistical results validate the new HRVM system against PPA for use in cloud computing and point-of-care testing.","PeriodicalId":51719,"journal":{"name":"Journal of Medical Physics","volume":"49 4","pages":"654-660"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0