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The Korean Journal of Medicine最新文献

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A New Korean Nomenclature for Steatotic Liver Disease 韩国脂肪肝新命名法
The Korean Journal of Medicine Pub Date : 2024-07-23 DOI: 10.3904/kjm.2024.038
{"title":"A New Korean Nomenclature for Steatotic Liver Disease","authors":"","doi":"10.3904/kjm.2024.038","DOIUrl":"https://doi.org/10.3904/kjm.2024.038","url":null,"abstract":"","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"63 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141813183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-carbapenem Drugs for Patients with Bacteremia caused by Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae: Piperacillin-Tazobactam 针对由产扩展谱β-内酰胺酶肠杆菌科细菌引起的菌血症患者的非碳青霉烯类药物：哌拉西林-他唑巴坦
The Korean Journal of Medicine Pub Date : 2024-06-01 DOI: 10.3904/kjm.2024.99.3.149
Hyunjoo Oh, Seunghee Lee, Misun Kim, S. Heo, J. Yoo
{"title":"Non-carbapenem Drugs for Patients with Bacteremia caused by Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae: Piperacillin-Tazobactam","authors":"Hyunjoo Oh, Seunghee Lee, Misun Kim, S. Heo, J. Yoo","doi":"10.3904/kjm.2024.99.3.149","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.3.149","url":null,"abstract":"Background/Aims: Carbapenems are recommended for treating bacteremia caused by extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae (ESBL-E). However, this has resulted in a significant rise in the utilization of carbapenems in cases of ESBL-E infection. We evaluated the clinical outcomes of patients with ESBL-E bacteremia treated with non-carbapenem antimicrobials.Methods: We conducted a retrospective case-control study of a cohort of patients with documented ESBL-E bacteremia from January 2021 to December 2021. The patients were divided into two groups according to whether they received non-carbapenem or carbapenem therapy. The rates of treatment failure, 30-day mortality and microbiologic failure, and the durations of hospitalization and of antimicrobial therapy were compared between the two groups. Antimicrobial susceptibility testing and phenotypic identification of ESBL-E were performed using the Vitek 2 system.Results: Of 118 patients with ESBL-E bacteremia, 54 received non-carbapenem drugs (non-carbapenem group [NCG]) and 64 received carbapenems (carbapenem group [CG]). Treatment failure at 30 days occurred in 16.7% of the patients in the NCG and in 18.8% in the CG (p = 0.65). The 30-day mortality rate was 14.8% in the NCG and 17.2% in the CG (p = 0.63). Extra-urinary tract infection and prior antimicrobial therapy within 30 days were risk factors for treatment failure in patients with ESBL-E bacteremia. The clinical outcomes did not differ significantly between the two groups, challenging the prevailing preference for carbapenems in the treatment of ESBL-E bacteremia.Conclusions: Non-carbapenem antimicrobials such as piperacillin/tazobactam are recommended for patients with mild ESBL-E bacteremia in South Korea.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141279136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Subclinical Hypothyroidism: The 2023 Korean Thyroid Association Guidelines 亚临床甲减的管理：2023 年韩国甲状腺协会指南
The Korean Journal of Medicine Pub Date : 2024-06-01 DOI: 10.3904/kjm.2024.99.3.127
Hyun-Kyung Chung
{"title":"Management of Subclinical Hypothyroidism: The 2023 Korean Thyroid Association Guidelines","authors":"Hyun-Kyung Chung","doi":"10.3904/kjm.2024.99.3.127","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.3.127","url":null,"abstract":"Subclinical hypothyroidism (SCH) is characterized by elevated serum thyroid-stimulating hormone (TSH) levels and normal free thyroxine levels. The Korean Thyroid Association recently issued guidelines for managing SCH. Based on the Korea National Health and Nutrition Examination Survey (2013-2015), a serum TSH level of 6.8 mIU/L is the reference value for SCH. SCH is classified as mild (TSH 6.8-10.0 mIU/L) or severe (TSH > 10.0 mIU/L), and patients are categorized as adult (age < 70 years) or elderly (age ≥ 70 years). Levothyroxine treatment (LT4-Tx) is not recommended for mild or even severe SCH in elderly patients. Immediate LT4-Tx can be given to adults in most cases, but not to women who are pregnant, patients with progressive disease, or patients with underlying coronary artery disease, heart failure, or dyslipidemia.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"1 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141275004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jaundice That Has Persisted for 5 Days 持续 5 天的黄疸
The Korean Journal of Medicine Pub Date : 2024-06-01 DOI: 10.3904/kjm.2024.99.3.140
Young Chang
{"title":"Jaundice That Has Persisted for 5 Days","authors":"Young Chang","doi":"10.3904/kjm.2024.99.3.140","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.3.140","url":null,"abstract":"Hepatitis B virus (HBV) reactivation associated with various therapeutic interventions is a significant cause of morbidity and mortality among patients with current or resolved HBV infection. Since no curative treatment for HBV infection is currently available, a large number of individuals in the general population are at risk for HBV reactivation. Populations vulnerable to HBV reactivation include those currently infected with HBV or those who have had past exposure to the virus. The potential consequences of HBV reactivation are particularly concerning when these populations undergo anti-cancer chemotherapy, immunosuppressive or immunomodulatory therapies for managing various malignancies, rheumatologic diseases, inflammatory bowel disease, or undergo solid-organ or hematologic stem cell transplantation. This article aims to increase awareness of HBV reactivation and to elucidate the mechanisms and risks associated with HBV reactivation in various clinical settings.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"38 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141280306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Acute Pyelonephritis Leading to Bilateral Subcapsular Renal Hematoma: A Case Report 急性肾盂肾炎导致双侧肾囊下血肿的罕见病例：病例报告
The Korean Journal of Medicine Pub Date : 2024-06-01 DOI: 10.3904/kjm.2024.99.3.158
Hae Won Park, Minsuk Seo, Chung Sik Lee
{"title":"A Rare Case of Acute Pyelonephritis Leading to Bilateral Subcapsular Renal Hematoma: A Case Report","authors":"Hae Won Park, Minsuk Seo, Chung Sik Lee","doi":"10.3904/kjm.2024.99.3.158","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.3.158","url":null,"abstract":"This case underscores the rarity of bilateral subcapsular renal hematoma (SCH) as a complication of acute pyelonephritis, and this is the first reported case in South Korea. SCH can have various underlying causes, including cysts, bleeding tendencies, cancer, vascular diseases and, less commonly, infections. A patient with uncontrolled diabetes mellitus and alcohol dependency presented with weakness. Bilateral SCH from acute pyelonephritis was diagnosed and treated with antibiotics and renal replacement therapy. Despite improved renal function, 30-day bilateral percutaneous drainage was necessary due to a persistent fever and elevated infection markers, resulting in a bloody, pus-like discharge. This case report sheds light on the rare etiology of bilateral SCH as a result of acute pyelonephritis. It serves as a reminder of the critical importance of timely intervention, to prevent deteriorating outcomes.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"1 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141281022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Significance and Interpretation of Allergen-Specific IgE Testing in Regard to Food Allergy 过敏原特异性 IgE 检测对食物过敏的临床意义和解释
The Korean Journal of Medicine Pub Date : 2024-06-01 DOI: 10.3904/kjm.2024.99.3.145
Hyun Jung Jin
{"title":"Clinical Significance and Interpretation of Allergen-Specific IgE Testing in Regard to Food Allergy","authors":"Hyun Jung Jin","doi":"10.3904/kjm.2024.99.3.145","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.3.145","url":null,"abstract":"Food allergy is an adverse reaction that occurs after ingesting food and is caused by an aberrant immune response. Taking a detailed medical history is the most important part of diagnosing food allergies. When an immunoglobulin E (IgE)-mediated food allergy is suspected, food-specific IgE testing can confirm the diagnosis. Allergen skin-prick tests or serum tests for specific IgE should be considered as the first line of testing, and depending on the offending food, a further prick-to-prick test with fresh food or a component-resolved diagnostic test may be helpful. Interpretation of the results should be based on the patient’s medical history.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"125 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141282049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updated Guidelines for Acute Coronary Syndrome 急性冠状动脉综合征的最新指南
The Korean Journal of Medicine Pub Date : 2024-06-01 DOI: 10.3904/kjm.2024.99.3.134
Sung Soo Kim, Hyun Kuk Kim
{"title":"Updated Guidelines for Acute Coronary Syndrome","authors":"Sung Soo Kim, Hyun Kuk Kim","doi":"10.3904/kjm.2024.99.3.134","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.3.134","url":null,"abstract":"Despite medical and invasive advancements, cardiovascular mortality attributable to ischemic heart disease, including acute coronary syndrome (ACS), persists at a substantial level. Clinical guidelines have been issued by the European Society of Cardiology (ESC) and American College of Cardiology/American Heart Association to support clinicians in making appropriate decisions and improving the prognosis of ACS patients. ESC recently introduced a new ACS guideline in August 2023. This review discusses the recent modification in the diagnosis and management of early-phase ACS in the 2023 ESC guideline.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"53 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141275039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Opportunity for Educational Innovations and Requirements in Academic System Reform of Medical Schools 医学院学制改革中的教育创新机遇与要求
The Korean Journal of Medicine Pub Date : 2024-06-01 DOI: 10.3904/kjm.2024.99.3.123
Bo Young Yoon
{"title":"The Opportunity for Educational Innovations and Requirements in Academic System Reform of Medical Schools","authors":"Bo Young Yoon","doi":"10.3904/kjm.2024.99.3.123","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.3.123","url":null,"abstract":"The amendment to the Higher Education Act enforced on February 20, 2024, abolishing the traditional 2-year pre-med and 4-year medical school programs, marks a significant shift in medical education in Korea. The academic system reform is expected to be a driving force for large-scale curriculum revision, presenting an opportunity to introduce new educational innovations not only in curriculum but also in student assessment and support systems. Addressing these challenges requires collaborative efforts among educators, students, and communities to navigate the evolving landscape of medical education effectively. In this regard, I will illustrate the recruitment and development of educators to implement the reform and the collaboration between communities and medical schools to innovate medical education.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"2015 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141400811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Progression of Incretin-Based Obesity Treatment 基于胰岛素的肥胖症治疗的最新进展
The Korean Journal of Medicine Pub Date : 2024-04-01 DOI: 10.3904/kjm.2024.99.2.78
Dughyun Choi
{"title":"Recent Progression of Incretin-Based Obesity Treatment","authors":"Dughyun Choi","doi":"10.3904/kjm.2024.99.2.78","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.2.78","url":null,"abstract":"Incretin-based obesity treatments are making remarkable progress, marking a new era in the field of obesity pharmacotherapy. These treatments not only meet the long-standing demands for safety and sustainability in obesity medications but also go beyond, significantly improving complications associated with obesity, such as cardiovascular diseases. This review explores the advancement in obesity treatments through the latest research findings on semaglutide and tirzepatide, two incretin-based obesity treatments currently receiving considerable attention.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"74 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140768420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Metapneumovirus Pneumonia-Related Acute Respiratory Distress Syndrome in a Young Adult Patient 一例年轻成人患者因跨肺病毒肺炎引发的急性呼吸窘迫综合征病例
The Korean Journal of Medicine Pub Date : 2024-04-01 DOI: 10.3904/kjm.2024.99.2.111
Tae Wan Kim, Won-Young Kim
{"title":"A Case of Metapneumovirus Pneumonia-Related Acute Respiratory Distress Syndrome in a Young Adult Patient","authors":"Tae Wan Kim, Won-Young Kim","doi":"10.3904/kjm.2024.99.2.111","DOIUrl":"https://doi.org/10.3904/kjm.2024.99.2.111","url":null,"abstract":"Human metapneumovirus (hMPV) infections commonly present as mild upper respiratory tract infections in healthy adults, although severe respiratory complications have been observed, particularly in elderly and immunocompromised patients. We report a case in whom pneumonia caused by hMPV progressed to acute respiratory distress syndrome (ARDS) in a healthy adult without underlying diseases. A 31-year-old female presented with fever and dyspnea, prompting transfer to our hospital for mechanical ventilation 3 days after symptom onset. Auscultation revealed coarse breath sounds and crackles in both lung fields, and chest X-ray showed non-specific infiltrative nodules with poorly defined borders throughout both lungs. ARDS caused by community-acquired pneumonia was diagnosed. hMPV was identified via rapid testing of respiratory samples for genes that encode pneumonia pathogens and drug resistance markers; we employed reverse transcription polymerase chain reactions to these ends. Six days later, the patient was weaned off the mechanical ventilator, and discharged from the hospital in good clinical condition.","PeriodicalId":517046,"journal":{"name":"The Korean Journal of Medicine","volume":"256 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140776256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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