持续 5 天的黄疸

Young Chang
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引用次数: 0

摘要

与各种治疗干预相关的乙型肝炎病毒(HBV)再激活是目前或已治愈的 HBV 感染患者发病和死亡的一个重要原因。由于目前还没有治疗 HBV 感染的方法,因此普通人群中的许多人都面临着 HBV 再激活的风险。易受 HBV 再激活影响的人群包括目前已感染 HBV 或过去曾接触过该病毒的人。当这些人群接受抗癌化疗、免疫抑制或免疫调节治疗以控制各种恶性肿瘤、风湿病、炎症性肠病,或接受实体器官或血液干细胞移植时,HBV 再激活的潜在后果尤其令人担忧。本文旨在提高人们对 HBV 再激活的认识,并阐明在各种临床环境中与 HBV 再激活相关的机制和风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Jaundice That Has Persisted for 5 Days
Hepatitis B virus (HBV) reactivation associated with various therapeutic interventions is a significant cause of morbidity and mortality among patients with current or resolved HBV infection. Since no curative treatment for HBV infection is currently available, a large number of individuals in the general population are at risk for HBV reactivation. Populations vulnerable to HBV reactivation include those currently infected with HBV or those who have had past exposure to the virus. The potential consequences of HBV reactivation are particularly concerning when these populations undergo anti-cancer chemotherapy, immunosuppressive or immunomodulatory therapies for managing various malignancies, rheumatologic diseases, inflammatory bowel disease, or undergo solid-organ or hematologic stem cell transplantation. This article aims to increase awareness of HBV reactivation and to elucidate the mechanisms and risks associated with HBV reactivation in various clinical settings.
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