Sustainable microbiology最新文献_第3页

Antarctic snow algal responses to temperature - potential implications of climate change. 南极雪藻对温度的响应——气候变化的潜在影响。

Sustainable microbiology Pub Date : 2026-06-01 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag023

Carla Ruiz Gonzalez, Vaila Grigg, Naomi Thomas, Alex Innes Thomson, Ewan MacPherson, Lara Dillon, Emilie Gober, Alison G Smith, Charles Cockell, Peter Convey, Matthew P Davey

{"title":"Antarctic snow algal responses to temperature - potential implications of climate change.","authors":"Carla Ruiz Gonzalez, Vaila Grigg, Naomi Thomas, Alex Innes Thomson, Ewan MacPherson, Lara Dillon, Emilie Gober, Alison G Smith, Charles Cockell, Peter Convey, Matthew P Davey","doi":"10.1093/sumbio/qvag023","DOIUrl":"10.1093/sumbio/qvag023","url":null,"abstract":"Snow algae are important primary producers in Antarctic terrestrial ecosystems. As short-term Antarctic summer temperatures approach 20°C, parameterising temperature tolerance for snow algal species is key to determining how climate change may affect community composition and primary productivity. We studied three Antarctic snow algae strains isolated from Ryder Bay, Adelaide Island (Antarctic Peninsula). The strains were exposed to 4, 8, 10, 12, 16, and 20°C across four laboratory experiments to assess the effects of temperature on growth, metabolite composition, and photochemistry. Growth of Limnomonas sp. and Chlorominima sp. was negatively affected at 8°C, and they did not survive at 20°C. Micractinium sp., conversely, grew well at all temperatures and displayed metabolic profiles similar to those of the temperate alga, Chlorella vulgaris. Photosynthetic parameters, measured by quantum yield (QY) curves, O2 production and pigment content, were minimally affected by temperature in Micractinium sp., whereas Limnomonas sp. showed reduced QY at temperatures of 8°C and above. Chlorominima sp. exhibited the greatest variation in QY and O2 production across temperature treatments. Our findings suggest that increased temperatures are likely to lead to changes in cryomicrobial community composition, with the psychrotolerant Micractinium sp. being more resilient to these changes.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag023"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148709309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surface materials and biofilm formation affect tropodithietic acid biosynthesis gene expression in Phaeobacter piscinae S26 and its interaction with Vibrio anguillarum. 表面材料和生物膜的形成影响鱼辉杆菌S26对滋养二酸生物合成基因的表达及其与鳗弧菌的相互作用。

Sustainable microbiology Pub Date : 2026-05-30 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag022

Xavier Ferrer-Florensa, Yuyan Liu, Mikael L Strube, Paul J Kempen, Claus Sternberg, Rafael Taboryski, Lone Gram

{"title":"Surface materials and biofilm formation affect tropodithietic acid biosynthesis gene expression in Phaeobacter piscinae S26 and its interaction with Vibrio anguillarum.","authors":"Xavier Ferrer-Florensa, Yuyan Liu, Mikael L Strube, Paul J Kempen, Claus Sternberg, Rafael Taboryski, Lone Gram","doi":"10.1093/sumbio/qvag022","DOIUrl":"10.1093/sumbio/qvag022","url":null,"abstract":"Tropodithietic acid (TDA) is the antimicrobial compound mediating the probiotic activity of Phaeobacter spp. against pathogenic vibrios in marine larviculture. In the related genera Tritonibacter, TDA is mainly produced during biofilm growth. The purpose of the study was to determine if biofilm formation increases expression of TDA biosynthesis genes in Phaeobacter piscinae and whether surface properties can promote this expression for aquaculture. Using a GFP reporter under the tdaCDE promoter and flow cytometry, TDA biosynthesis gene expression was two-fold higher in biofilms than in planktonic cells. Biofilm formation on four surfaces showed that the most hydrophobic material, PDMS, supported ∼30-fold higher early attachment than PMMA, COC and PP, while mature biovolume was similar across materials. The TDA gene expression to biovolume ratio increased as biofilms developed. P. piscinae biofilms inhibited Vibrio anguillarum, reducing counts to 105 CFU/ml compared to the control that was 108 CFU/ml. In the presence of V. anguillarum, PDMS biofilms showed 1.5-fold higher biovolume and 2.5-fold higher TDA biosynthesis gene expression, suggesting an antagonistic response. Thus, Phaeobacter is a more effective Vibrio antagonist in the biofilm state, supporting its potential as a probiotic for future aquaculture applications.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag022"},"PeriodicalIF":0.0,"publicationDate":"2026-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13409315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustainable rewilding of urban spaces increases microbial diversity. 城市空间的可持续重建增加了微生物的多样性。

Sustainable microbiology Pub Date : 2026-05-22 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag020

Mika Saarenpää, Juulia Manninen, Damiano Cerrone, Juho Rajaniemi, Marja I Roslund, Aki Sinkkonen

{"title":"Sustainable rewilding of urban spaces increases microbial diversity.","authors":"Mika Saarenpää, Juulia Manninen, Damiano Cerrone, Juho Rajaniemi, Marja I Roslund, Aki Sinkkonen","doi":"10.1093/sumbio/qvag020","DOIUrl":"10.1093/sumbio/qvag020","url":null,"abstract":"Soil sealing and biodiversity loss are major drivers of altered microbial communities in urban environments. Little is known about how rewilding reshapes these communities and enriches surrounding sealed surfaces with microbiota. To fill this gap, we first tested whether existing urban green spaces are associated with increased microbial diversity and abundance beyond their boundaries on adjacent impermeable surfaces. We then rewilded a barren, sealed city square using vegetation, compost-based growing medium, and decaying wood. We hypothesized that proximity to green spaces predicts microbial communities more than geographic location, and that rewilding enriches bacterial diversity on nearby sealed surfaces, with diminishing effects across distance. Microbial samples were collected from five green spaces at 0-100 m distances, and from the rewilded and a neighboring non-rewilded square before and after rewilding. In the green space experiment, bacterial richness and relative abundance of Rhizobacter declined steadily with distance from green spaces. In the rewilding experiment, bacterial alpha diversity increased compared to baseline conditions and co-occurrence networks contained more nodes and connections post-rewilding. These findings demonstrate that existing green spaces are associated with elevated microbial diversity on surrounding sealed surfaces, and that rewilding urban areas provides a low-cost, nature-based strategy to increase urban microbial diversity.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag020"},"PeriodicalIF":0.0,"publicationDate":"2026-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148709055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of Geobacter sulfurreducens and Geobacter species in sustainable development. 硫还原地杆菌及其种类在可持续发展中的作用。

Sustainable microbiology Pub Date : 2026-05-15 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag019

Dario R Shaw, Hari Ananda Rao, Pascal E Saikaly

{"title":"The role of Geobacter sulfurreducens and Geobacter species in sustainable development.","authors":"Dario R Shaw, Hari Ananda Rao, Pascal E Saikaly","doi":"10.1093/sumbio/qvag019","DOIUrl":"10.1093/sumbio/qvag019","url":null,"abstract":"Geobacter sulfurreducens is a model electroactive bacterium whose remarkable extracellular electron transfer capabilities bridge microbiology, materials science, and sustainability. Over the past two decades, its metabolism has been harnessed for clean energy generation, wastewater treatment, and the development of environmentally friendly electronic materials. Its metabolic versatility aligns with multiple of the United Nations Sustainable Development Goals (SDGs). In environmental systems, Geobacter reduces toxic and radioactive metals to insoluble, stable forms, detoxifies organic pollutants, and mitigates methane emissions in anoxic soils, contributing to climate action and water quality (SDGs 6 and 13). At the materials frontier, Geobacter produces conductive protein nanowires that enable biological electronics and biosensors, opening new avenues for biodegradable, renewable electronic devices (SDGs 7 and 9). Moreover, its redox machinery allows ambient-temperature synthesis of catalysts, including single-atom and nanocluster metals, offering green alternatives to conventional high-energy synthesis processes (SDG 12). Taken together, G. sulfurreducens exemplifies how microbial metabolism can be engineered toward circular bioeconomy solutions that integrate pollution control, energy recovery, and material innovation. As research advances, this organism continues to define a new paradigm of \"sustainable microbiology,\" in which living systems serve as platforms for next-generation green technologies.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag019"},"PeriodicalIF":0.0,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148709088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Yellow fever in older adults: an overlooked high-risk population in South American outbreaks. 老年人黄热病：南美疫情中被忽视的高危人群

Sustainable microbiology Pub Date : 2026-05-08 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag018

Alfonso J Rodriguez-Morales

{"title":"Yellow fever in older adults: an overlooked high-risk population in South American outbreaks.","authors":"Alfonso J Rodriguez-Morales","doi":"10.1093/sumbio/qvag018","DOIUrl":"10.1093/sumbio/qvag018","url":null,"abstract":"Yellow fever (YF) remains a re-emerging public health threat in South America, with recent outbreaks reporting high case-fatality rates. Although transmission has predominantly affected rural and sylvatic populations, mounting evidence indicates that older adults experience disproportionately severe outcomes and mortality. This commentary highlights the elderly as an overlooked high-risk group in the current epidemiological landscape. Age-related immunosenescence, comorbidities, endothelial dysfunction, and reduced hepatic reserve likely amplify the pathophysiological impact of YF virus infection. At the same time, concerns about vaccine-associated adverse events in individuals ≥60 years complicate risk-benefit decision-making, contributing to under-vaccination in this vulnerable population. Delayed diagnosis and shifting eco-epidemiological patterns further exacerbate risk. As South America undergoes demographic aging alongside environmental change, targeted, age-specific strategies, including prioritized vaccination, tailored risk communication, and enhanced surveillance for older adults, are urgently needed to reduce preventable fatalities.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag018"},"PeriodicalIF":0.0,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148709096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persister cells form based on low ribosome content in Escherichia coli. 大肠杆菌中核糖体含量低，形成持久性细胞。

Sustainable microbiology Pub Date : 2026-05-07 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag017

Hyeon-Ji Hwang, Rodolfo García-Contreras, Michael J Benedik, Thomas K Wood

{"title":"Persister cells form based on low ribosome content in Escherichia coli.","authors":"Hyeon-Ji Hwang, Rodolfo García-Contreras, Michael J Benedik, Thomas K Wood","doi":"10.1093/sumbio/qvag017","DOIUrl":"10.1093/sumbio/qvag017","url":null,"abstract":"Persister cells survive severe stresses, including antibiotics, starvation, heat, oxidative conditions, and phage attack, by entering a dormant physiological state. They arise without genetic change and can resume growth once the stress is removed and nutrients are available. Critically, upon resuscitation, disease-causing persister cells can reconstitute infections. Although it is known that persister cells resuscitate in proportion to their ribosome content, it has remained unclear whether ribosome levels also influence the formation of persister cells. Here, we used fluorescence-activated cell sorting (FACS) to fractionate exponentially growing Escherichia coli cells into four populations spanning low to high ribosome levels and demonstrated, via antibiotic survival assays with both ampicillin and ciprofloxacin, that cells with low ribosome content form persister cells approximately 80-fold (ampicillin) and 50-fold (ciprofloxacin) more frequently than cells with population-average ribosome levels. These findings show that persister cell formation is inversely proportional to ribosome abundance. Cells with low ribosome levels are less metabolically active and therefore less capable of initiating stress responses like most cells; instead, they enter a dormant state in which antibiotic target activity is reduced, thereby promoting persister formation.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag017"},"PeriodicalIF":0.0,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148709025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Community-driven solutions for the AMR problem: outcomes from a regulator-innovator workshop on challenges across AMR innovation, access, and adoption. AMR问题的社区驱动解决方案：监管机构-创新者研讨会关于AMR创新、获取和采用方面的挑战的成果。

Sustainable microbiology Pub Date : 2026-04-30 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag016

Leanne Cleaver, Matthew Lamaudiere, Neil Almond, Carmen H Coxon

{"title":"Community-driven solutions for the AMR problem: outcomes from a regulator-innovator workshop on challenges across AMR innovation, access, and adoption.","authors":"Leanne Cleaver, Matthew Lamaudiere, Neil Almond, Carmen H Coxon","doi":"10.1093/sumbio/qvag016","DOIUrl":"10.1093/sumbio/qvag016","url":null,"abstract":"Antimicrobial resistance (AMR) is a global threat that requires innovative solutions to protect our future and avoid repeating the mistakes of our past. To do this, innovation and regulation need to work together to deliver new therapeutics, diagnostics, and vaccines in a timely and risk-proportionate manner. Funders recognize that providing product developers with access to technical, regulatory, and experiential knowledge derisks their investment and maximizes the likelihood of success. The Global Antimicrobial Innovation Fund (GAMRIF) is a global funder in AMR innovation across One Health with a Lower Middle-Income Country focus; in 2024, it increased its innovator support structure to include a regulatory science team at the Medicines and Healthcare products Regulatory Agency (MHRA). As part of its discovery work, the GAMRIF-MHRA team held a 2-day meeting convening innovators, product developers, manufacturers, regulators, funders, and access and policy experts to interrogate the product journey across development, regulation, manufacturing, and market access to identify common challenges and generate practical solutions to address them. Here we present a summary of the meeting content, and recommendations and next steps based on delegate engagement and feedback.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag016"},"PeriodicalIF":0.0,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148709303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nepal's vulnerability to Nipah virus transmission: an urgent call for preparedness. 尼泊尔易受尼帕病毒传播的影响：紧急呼吁做好准备。

Sustainable microbiology Pub Date : 2026-04-25 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag015

Bhupendra Lama, Uday Narayan Yadav, Gopiram Syangtan, Alaka Bhandari, Binod Gc, Mukesh Rai, Martyn D Kirk, Binod Rayamajhee

{"title":"Nepal's vulnerability to Nipah virus transmission: an urgent call for preparedness.","authors":"Bhupendra Lama, Uday Narayan Yadav, Gopiram Syangtan, Alaka Bhandari, Binod Gc, Mukesh Rai, Martyn D Kirk, Binod Rayamajhee","doi":"10.1093/sumbio/qvag015","DOIUrl":"10.1093/sumbio/qvag015","url":null,"abstract":"The confirmation of two Nipah virus (NiV) infections among healthcare workers in West Bengal, India, in December 2025 highlights the ongoing regional threat of this highly contagious zoonotic pathogen and the risk of nosocomial transmission before clinical suspicion. Increasing reports of human-to-human transmission in South Asia call for stronger preparedness efforts in neighboring countries. Nepal is particularly vulnerable due to its open border with India, high population mobility, ecological suitability for Petropus bat reservoirs, mixed livestock farming, limited surveillance, and diagnostic capacity. The absence of reported cases likely reflects underdetection rather than the absence of risk. Current gaps include weak infection prevention and control, limited laboratory readiness, minimal wildlife and livestock surveillance, and inadequate cross-border coordination. We propose priority actions based on the One Health approach, including bat roost mapping, cross-border information sharing, targeted community risk communication, strengthening tertiary hospitals and laboratory capacity, enhanced veterinary surveillance, and the development of a national outbreak preparedness and response plan for future potential NiV or other emerging pathogen outbreaks.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag015"},"PeriodicalIF":0.0,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148709015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-infective compounds for Yersinia. 耶尔森菌的抗感染化合物。

Sustainable microbiology Pub Date : 2026-04-11 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag014

Kumar D Gahlot, Matthew S Francis, Jyoti M Gurung

引用次数: 0

Insights into trehalose synthase function in the rhizobium Paraburkholderia phymatum STM815^T under abiotic stresses and during symbiosis. 藻糖合成酶在非生物胁迫和共生过程中的作用。

Sustainable microbiology Pub Date : 2026-04-03 eCollection Date: 2026-01-01 DOI: 10.1093/sumbio/qvag013

Daphne Golaz, Gabriella Pessi

{"title":"Insights into trehalose synthase function in the rhizobium Paraburkholderia phymatum STM815T under abiotic stresses and during symbiosis.","authors":"Daphne Golaz, Gabriella Pessi","doi":"10.1093/sumbio/qvag013","DOIUrl":"10.1093/sumbio/qvag013","url":null,"abstract":"The beta-proteobacterium Paraburkholderia phymatum STM815T is a diazotrophic rhizobium that is highly competitive for legume root nodulation and is resistant to abiotic stresses, including heat, low pH, or drought stress. A gene coding for a potential trehalose synthase and localized on the symbiotic plasmid (Sp treS) was among the most highly upregulated genes in microoxic conditions and in symbiosis. In this study, we observed that cells grown in microaerobic conditions produced 5.8 times more trehalose than in aerobic conditions. Accordingly, a P. phymatum Sp treS mutant accumulated 29.5% less trehalose than the wild-type strain in microaerobic conditions. During symbiosis with common bean, the Sp treS mutant showed a 58.8% lower nitrogenase activity compared to the wild-type strain. Furthermore, in absence of Sp treS P. phymatum was more sensitive to H2O2-induced oxidative stress and to freezing conditions and formed filaments. These results expand our knowledge on the behavior of this beta-rhizobium under microoxic conditions and on the role of the enzyme trehalose synthase in rhizobial resistance to abiotic stresses and in symbiotic efficiency.","PeriodicalId":516860,"journal":{"name":"Sustainable microbiology","volume":"3 2","pages":"qvag013"},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0