Journal of conservative dentistry and endodontics最新文献_第10页

Innovative management of complicated crown-root fracture with biomimetic materials: A case report with a 2-year follow-up. 采用仿生材料创新治疗复杂冠根骨折1例，随访2年。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_670_24

Maninder Kaur, Munish Singla, Harleen Kaur, Saloni Gupta, Reetu Arora

引用次数: 0

To compare and evaluate microcracks and smear layer after root end preparation by laser, ultrasonic tip, and conventional bur in single-rooted teeth: "Scanning electron microscope study". 比较和评价单根牙激光、超声针尖和常规针尖制备牙根后的微裂纹和涂抹层：“扫描电镜研究”。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_733_24

Jyotirmoyee Bhanja, Shyam Agrawal, Rachit Mathur, Deepak Sharma, Shaista Gazal, Anuja Ray Awadesh

{"title":"To compare and evaluate microcracks and smear layer after root end preparation by laser, ultrasonic tip, and conventional bur in single-rooted teeth: \"Scanning electron microscope study\".","authors":"Jyotirmoyee Bhanja, Shyam Agrawal, Rachit Mathur, Deepak Sharma, Shaista Gazal, Anuja Ray Awadesh","doi":"10.4103/JCDE.JCDE_733_24","DOIUrl":"10.4103/JCDE.JCDE_733_24","url":null,"abstract":"Aim: Evaluation of root-end cavities for the existence of microcracks and smear layer with laser, ultrasonic tip by conventional bur, and control group in single-rooted tooth by scanning electron microscope (SEM).Methodology: Fifty-two extracted fully developed single-rooted teeth were decoronated, cleaned, shaped, and obturated with F2 GP, and 3 mm roots were removed. Laser, ultrasonic tip (AS 3Dretro-tip on Newtron-SATELEC, Acteon), and conventional bur (size 010 round) were used to create root-end preparation. No root-end cavities were produced in the control group. SEM was used to check all samples for microcracks and smear layers.Results: A significant difference was found between microcrack formation in laser and conventional bur preparation (P = 0.002), and ultrasonic and laser (P = 0.015). Nonsignificant difference was found between ultrasonic and conventional bur (P = 0.046). The study concluded that maximum cracks were seen in conventional bur formation at the apical end of the root (0.85 ± 0.36) followed by the ultrasonic method (0.54 ± 0.23).Conclusion: Root-end cavities prepared with laser give fewer microcracks and less production of smear layer compared to the ultrasonic tip and conventional bur.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"16-20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of Biodentine and Mineral Trioxide Aggregate repair High Plasticity in reinforcing roots with perforation: An in vitro study. 生物牙髓素与三氧化二矿骨料修复高塑性根穿孔的比较研究。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_711_24

R Anija, Chandana Kalita, S L Satheesh, Mukut Seal, Tribisha Kalita, Anindita Saikia

{"title":"Comparative analysis of Biodentine and Mineral Trioxide Aggregate repair High Plasticity in reinforcing roots with perforation: An in vitro study.","authors":"R Anija, Chandana Kalita, S L Satheesh, Mukut Seal, Tribisha Kalita, Anindita Saikia","doi":"10.4103/JCDE.JCDE_711_24","DOIUrl":"10.4103/JCDE.JCDE_711_24","url":null,"abstract":"Context: Root perforation increases the fracture risk, and bioceramic materials can be used for repair. Evaluating the fracture resistance (FR) of these cements in teeth with simulated perforations is crucial for assessing their effectiveness.Aim: The aim of the study was to evaluate the effect of Biodentine (Septodont, France) and Mineral Trioxide Aggregate High Plasticity (MTA Repair HP, Angelus, Brazil), on the FR of teeth with simulated root perforations.Design and settings: An in vitro experimental design was conducted to compare and determine the most reliable repair and obturating material for root perforation.Materials and methods: Fifty extracted mandibular premolars were randomly assigned to one control group (n = 10) and four test groups (n = 10) based on the repair and backfilling materials used: Biodentine + gutta percha (GP) (Dentsply Maillefer, Germany) and AH Plus sealer (Dentsply, Germany), Biodentine + Biodentine, MTA HP + GP and sealer, and MTA HP + MTA HP. FR was assessed using a universal testing machine.Statistical analysis: The variance among the five groups was tested using Analysis of Variance and pairwise post hoc Tukey's test for intergroup comparisons. The level of statistical significance was set at P < 0.05.Results: The highest mean FR value was observed in the MTA HP + MTA HP group. ANOVA test revealed statistically significant differences between the groups (P < 0.05).Conclusion: Bioceramic cements with a MOE similar to dentin enhance FR by forming a monoblock for uniform stress distribution. Perforation repair and backfilling with these cement reinforce the tooth.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of silver-graphene oxide nanoparticle against Enterococcus faecalis biofilms in the root canal. 氧化银石墨烯纳米颗粒对根管内粪肠球菌生物膜的影响。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_701_24

Sadhana Majhi, Elkanti Soujanya, Mamta Kaushik, X Nagamaheshwari, Yesha Yadav, Simran Kaur

{"title":"Effectiveness of silver-graphene oxide nanoparticle against Enterococcus faecalis biofilms in the root canal.","authors":"Sadhana Majhi, Elkanti Soujanya, Mamta Kaushik, X Nagamaheshwari, Yesha Yadav, Simran Kaur","doi":"10.4103/JCDE.JCDE_701_24","DOIUrl":"10.4103/JCDE.JCDE_701_24","url":null,"abstract":"Aim: This study aims to assess the effectiveness of silver-graphene oxide (AgGO) nanoparticles against Enterococcus faecalis biofilm and smear layer in comparison with 3% sodium hypochlorite (NaOCl) and 2% chlorhexidine (CHX) using passive ultrasonic irrigation (PUI) technique.Subjects and methods: Eighty single-rooted teeth were collected, sterilized, and prepared for this study. E. faecalis was inoculated into the root canals and incubated for 21 days. Teeth were divided into four groups for irrigation: Group I (0.25% AgGO), Group II (3% NaOCl), Group III (2% CHX), and Group IV (0.9% saline), followed by PUI. Microbiological evaluation was performed by collecting bacterial samples and quantifying colony-forming units/ml. Scanning electron microscope was used to assess biofilm and smear layer removal.Statistical analysis used: Kruskal-Wallis test, Bonferroni correction, intraclass correlation test.Results: Antibacterial activity and smear layer removal were highest in Group II followed by Group I and Group III which showed similar results. Group IV showed the least results.Conclusions: 3% NaOCl was the most effective solution in terms of antibacterial activity and smear layer removal. 0.25% AgGO and 2% CHX showed moderate effectiveness in removing E. faecalis biofilms and smear layer which suggests that both have potential as alternative irrigants.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"27-32"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Augmenting quality of life and mental health through the promotion of accessible root canal therapy. 通过推广可获得的根管治疗，提高生活质量和精神健康。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_826_24

Saurabh RamBihariLal Shrivastava, Prateek Sudhakar Bobhate, Gulshan Bandre

{"title":"Augmenting quality of life and mental health through the promotion of accessible root canal therapy.","authors":"Saurabh RamBihariLal Shrivastava, Prateek Sudhakar Bobhate, Gulshan Bandre","doi":"10.4103/JCDE.JCDE_826_24","DOIUrl":"10.4103/JCDE.JCDE_826_24","url":null,"abstract":"Root canal therapy (RCT) is an extremely safe, effective, and painless procedure that is crucial to save a tooth that would have been otherwise extracted. As patients with tooth infections present with severe pain and inability to carry out routine oral functions, RCT plays a vital role in improving the quality of life of the patients. The RCT procedure not only plays a crucial role in the relief of physical pain but also significantly contributes to mental well-being. After realizing the benefits of RCT in improving the quality of life and positive impact on the mental well-being of the patients, we anticipate that all patients must timely receive the therapy, but then that is not the case due to the presence of various challenges and factors. The presence of these barriers envisages the need for the formulation of comprehensive policies, expansion of community outreach activities, and education of patients to improve access to RCT. In conclusion, RCT has been associated with multiple benefits. There arises the need to overcome the identified barriers to ensure that RCT becomes more accessible for a wide range of patients needing essential dental services.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"106-108"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The reliability and validity of the restoration difficulty evaluation system tool for assessing the restoration of endodontically treated teeth: A pilot study. 评估根管治疗后牙齿修复难度评估系统工具的可靠性和有效性：一项初步研究。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_598_24

Angad Mahajan, Ruchika Roongta Nawal, Sangeeta Talwar, Minaal Verma, Sudha Yadav

{"title":"The reliability and validity of the restoration difficulty evaluation system tool for assessing the restoration of endodontically treated teeth: A pilot study.","authors":"Angad Mahajan, Ruchika Roongta Nawal, Sangeeta Talwar, Minaal Verma, Sudha Yadav","doi":"10.4103/JCDE.JCDE_598_24","DOIUrl":"10.4103/JCDE.JCDE_598_24","url":null,"abstract":"Introduction: Restoration of endodontically treated teeth (ETT) is crucial for their long-term functionality, yet current practices lack structured approaches, leading to variable outcomes. The restorative difficulty evaluation system (RDES) offers a systematic method to assess restoration complexity tailored to each patient. This pilot study aims to evaluate RDES's reliability and validity in guiding clinicians' decisions on ETT restoration.Methodology: Ten participants were recruited, and two endodontists independently assessed clinical parameters using RDES. Interrater reliability was assessed to determine agreement between examiners. Test-retest reliability was evaluated over two time points (baseline and 2 weeks). Face and content validity were assessed by a panel of 10 experts.Results: Intrarater reliability was robust (Evaluator 1: r = 0.667 and Evaluator 2: r = 0.655). Interrater reliability was substantial (κ =0.783). Face validity affirmed RDES parameters' relevance with scores exceeding the impact score threshold. Content validity showed high item-rated content validity index (I-CVI) scores for both relevance (I-CVI [R]) and clarity (I-CVI [C]), resulting in high scale-level CVI scores, affirming all RDES items' appropriateness. The Gunning Fog Index (14.79) suggests tool's suitability for college junior or undergraduate-level readers.Conclusion: The study demonstrates RDES's reliability and validity in assessing restoration complexity in ETT. Its systematic approach can inform treatment decisions, potentially enhancing patient outcomes.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative evaluation of three accidentally extruded sealers in periapical healing - An evidence - based study. 三种意外挤压封口剂在根尖周愈合中的比较评价-一项基于证据的研究。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_728_24

Ajay Chhabra, Priyanka Yadav, Bhupendra Babaria, Ritesh Singh, Vandana Chhabra, B Saravana Prathap, K P Ramya

{"title":"Comparative evaluation of three accidentally extruded sealers in periapical healing - An evidence - based study.","authors":"Ajay Chhabra, Priyanka Yadav, Bhupendra Babaria, Ritesh Singh, Vandana Chhabra, B Saravana Prathap, K P Ramya","doi":"10.4103/JCDE.JCDE_728_24","DOIUrl":"10.4103/JCDE.JCDE_728_24","url":null,"abstract":"Background: The present study aimed to evaluate the periapical healing of root canal treatment after accidental extrusion and rate of resorption of three different base endodontic sealers.Materials and methods: Seventy-five patients with single visit root canal treated teeth with accidental extrusion of sealer were selected based on inclusion and exclusion criteria and were allocated into three equal groups based on different base endodontic sealers used during obturation; Grossman, Sealapex™, and Seal-pex. Radiographic evaluation was done to assess periapical healing and rate of resorption at baseline, 1, 3, and 6 months. Statistical analysis was done using one-way repeated measured analysis of variance.Results: At the end of 6 months in Group 1 (Grossman), healing was rated as unchanged in 0 patients (0%), reduced in 0 patients (0%), almost absent in 2 patients (8%) and absent in 23 patients (92%). In Group 2 (sealapex), healing was rated as unchanged in 1 patient (4%), reduced in 6 patients (24%), almost absent in 6 patients (24%), and absent in 12 patients (48%). In Group 3 (seal-pex), healing was rated as unchanged in 2 patients (8%), reduced in 10 patients (40%), almost absent in 6 patients (24%) and absent in 7 patients (28%).Conclusions: Sealapex™ has shown better periapical lesion healing compared to Grossman Sealer and Seal-pex and Grossman Sealer had shown faster rate of resorption compared to Sealapex™ and seal-pex™.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"68-77"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"Résorption radiculaire interne:" A case report on dual-phase management of extensive internal root resorption. “根瘤菌吸收：广泛内根吸收双阶段治疗1例”。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_433_24

Ipsita Maity, Lovely Das, Paromita Mazumdar, Kushal Kumar Ghosh

{"title":"\"Résorption radiculaire interne:\" A case report on dual-phase management of extensive internal root resorption.","authors":"Ipsita Maity, Lovely Das, Paromita Mazumdar, Kushal Kumar Ghosh","doi":"10.4103/JCDE.JCDE_433_24","DOIUrl":"10.4103/JCDE.JCDE_433_24","url":null,"abstract":"This case study delves into an uncommon occurrence of internal root resorption (IRR), an inflammatory variant with perforation of root, in the left central incisor, which seems to have a prevalence ranging from 0.01% to 1%. The patient presented with pain in the upper left front tooth, leading to a diagnosis of pulpal necrosis with symptomatic apical periodontitis. The initial phase involved identifying the three-dimensional overview of resorption and perforation using cone-beam computed tomography and nonsurgical root canal treatment utilizing orthograde mineral trioxide aggregate (MTA) placement and thermoplasticized obturation technique, aided by sonic-irrigation, and intracanal medicament under magnification. In the later phase, based on the clinical and radiographical evaluation and addressing the complexities of the perforative resorptive lesion, surgical approach needed to be performed. A 6-month follow-up revealed the arrest of IRR and a satisfactory overall outcome. This case report discusses the etiology, prevalence, clinical decision-making, and therapeutic management of IRR.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"101-105"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro cytotoxicity evaluation of endodontic irrigants combined with cationic peptide. 牙髓冲洗剂联合阳离子肽的体外细胞毒性评价。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_690_24

M Praveen Kumar, Shravan Kini, M S Prathap, Aravind R Kudva, Aboobacker Sidheeque, Ashwini Prabhu

{"title":"In vitro cytotoxicity evaluation of endodontic irrigants combined with cationic peptide.","authors":"M Praveen Kumar, Shravan Kini, M S Prathap, Aravind R Kudva, Aboobacker Sidheeque, Ashwini Prabhu","doi":"10.4103/JCDE.JCDE_690_24","DOIUrl":"10.4103/JCDE.JCDE_690_24","url":null,"abstract":"Aim: The aim of this study was to assess the cytotoxicity of endodontic irrigants 2% chlorhexidine (CHX) and ethylenediaminetetraacetic acid (EDTA) combined with cationic peptide DJK-5 on L929 mouse subcutaneous fibroblast cells.Subjects and methods: L929 cells were cultured and treated with 2% CHX, 2% CHX + DJK-5, 8.5% EDTA, 8.5% EDTA + DJK-5, and DJK-5 alone (DJK-5 peptide concentration-10 μg/mL) for 24 and 48 h. The cytotoxicity of the endodontic irrigants was determined using methyl thiazolyl tetrazolium assay and Live/Dead assay using acridine orange and ethidium bromide dual fluorescence staining.Statistical analysis used: The Shapiro-Wilk test was used to verify the normality of the data within each group at two different time points. Parametric tests were used for the comparison. Paired sample t-test was used for the comparison of the cytotoxicity of irrigants over time. One-way ANOVA was employed for the comparison of the cytotoxicity of irrigants. Tukey's test was used for pairwise comparison between groups. SPSS software version 27 was used for the data analyses.Results: CHX exhibited slight cytotoxicity at 24 h and higher cytotoxicity at 48 h (P < 0.05). EDTA showed better cell viability than CHX at both time points. In combination groups, the EDTA + DJK-5 group showed lower cytotoxicity at both time points (P > 0.05). The combination of CHX with DJK-5 reduced the cytotoxicity of CHX (P < 0.05).Conclusions: The cytotoxicity of endodontic irrigants was found to be time dependent. CHX was found to be highly cytotoxic at 2% concentration. DJK-5 was found to have the least cytotoxicity, and it significantly reduced the cytotoxicity of CHX and EDTA.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"84-89"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial efficacy of modified gutta-percha for obturation - A systematic review. 改良杜仲胶用于闭合术的抗菌效果的系统评价。

Journal of conservative dentistry and endodontics Pub Date : 2025-01-01 Epub Date: 2025-01-13 DOI: 10.4103/JCDE.JCDE_678_24

G Manobharathi, Sandhya Raghu, Aruna Krishnan

{"title":"Antimicrobial efficacy of modified gutta-percha for obturation - A systematic review.","authors":"G Manobharathi, Sandhya Raghu, Aruna Krishnan","doi":"10.4103/JCDE.JCDE_678_24","DOIUrl":"10.4103/JCDE.JCDE_678_24","url":null,"abstract":"Gutta Percha (GP) cones are made in an aseptic environment, a number of investigations have shown the presence of bacteria in recently opened boxes and this contamination rises with incorrect handling, storage and aerosol application. Numerous physicochemical techniques have been documented aiming to boost the antibacterial activity of GP cones while ensuring its obturation requirements. This systematic review aimed to critically evaluate the efficacy of antibacterial activity of GP modified with various antibacterial agents. The protocol for this systematic review has been registered with the PROSPERO International prospective register of systematic reviews, registry No. CRD42024573067. The search was carried out across reputable databases, including PubMed/Medline, Web of Science, Scopus and it was specifically designed to include articles published until March 2024. The search queries in the database were formulated with the basis of PICO questions in combination with various Boolean operators such as AND, OR. MeSH terms used for the search included GP, antibacterial agents, nanoparticles, root canal treatment, medicated GP. The extraction of the information was done by two independent authors. The evaluation of the methodological quality of the included studies was assessed using QUIN TOOL. This systematic review was reported following the Preferred Reporting Items for Systematic Reviews (PRISMA 2020) guidelines. Initial search yielded 51 studies from database search. Out of 51, 9 articles ultimately satisfied the requirements and were therefore discussed in the current systematic review. The included studies were assessed and data were extracted and tabulated. Based on the results of the current systematic review, modified GP with various antimicrobial agents showed significantly increased antibacterial effectiveness than standard GP.","PeriodicalId":516842,"journal":{"name":"Journal of conservative dentistry and endodontics","volume":"28 1","pages":"2-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0