Plastic & Reconstructive Surgery-Global Open最新文献

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Multiple Buttresses Reconstruction of Maxilla with Fibular Flap Using Computer-aided Design/Computer-aided Manufacturing after Maxillectomy 上颌骨切除术后利用计算机辅助设计/计算机辅助制造技术用腓骨瓣重建上颌骨的多臼齿

Plastic & Reconstructive Surgery-Global Open Pub Date : 2024-06-01 DOI: 10.1097/GOX.0000000000005914

Koreyuki Kurosawa, Naoko Sato, Akira Ohkoshi, Takayuki Harata, Shinyo Ishi, Masanobu Hayashi, Toshiro Imai, Nariaki Takamura, Hiromu Matsunaga, Yoshimichi Imai

{"title":"Multiple Buttresses Reconstruction of Maxilla with Fibular Flap Using Computer-aided Design/Computer-aided Manufacturing after Maxillectomy","authors":"Koreyuki Kurosawa, Naoko Sato, Akira Ohkoshi, Takayuki Harata, Shinyo Ishi, Masanobu Hayashi, Toshiro Imai, Nariaki Takamura, Hiromu Matsunaga, Yoshimichi Imai","doi":"10.1097/GOX.0000000000005914","DOIUrl":"https://doi.org/10.1097/GOX.0000000000005914","url":null,"abstract":"Background: The maxilla comprises horizontal and vertical buttresses, each with specific functions, supporting various organs, such as the eyes, nose, and oral cavity. Notably, they combine to form a three-dimensional structure, which enables the buttresses to provide their inherent support strength. However, reconstructing the maxilla after maxillectomy by assembling new buttresses is challenging. We successfully reconstructed all the buttresses crucial for facial appearance and dental rehabilitation using a vascularized fibular flap. Methods: Four patients underwent maxillary buttress reconstruction with a fibular flap after total or subtotal maxillectomy. We used computer-aided design/computer-aided manufacturing digital technology to osteotomize the fibula into multiple segments and assemble them to reconstruct the maxillary buttresses. Each buttress was assembled based on a preoperative simulation. Results: All patients underwent immediate one-stage maxillary reconstruction. They had good maxillary buttress alignment and acquired good facial appearance, eye position, nasal airway, and prosthetically suitable maxillary alveolus ridge. Conclusions: The combination of computer-aided design/computer-aided manufacturing digital technology and surgical techniques has enabled novel maxillary reconstruction, providing great hope to patients experiencing facial disfigurement and loss of function after maxillectomy.","PeriodicalId":516238,"journal":{"name":"Plastic & Reconstructive Surgery-Global Open","volume":"62 3","pages":"e5914"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141403868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breast Cancer Immunotherapy: A Clinical Review for the Plastic Surgeon 乳腺癌免疫疗法：整形外科医生临床综述

Plastic & Reconstructive Surgery-Global Open Pub Date : 2024-06-01 DOI: 10.1097/GOX.0000000000005915

Matthew J. Heron, Katherine J. Zhu, Lily Zhu, Jeffrey Khong, Lily R. Mundy, Mehran Habibi, Kristen P. Broderick

{"title":"Breast Cancer Immunotherapy: A Clinical Review for the Plastic Surgeon","authors":"Matthew J. Heron, Katherine J. Zhu, Lily Zhu, Jeffrey Khong, Lily R. Mundy, Mehran Habibi, Kristen P. Broderick","doi":"10.1097/GOX.0000000000005915","DOIUrl":"https://doi.org/10.1097/GOX.0000000000005915","url":null,"abstract":"Background: Immunotherapy has transformed breast cancer management. However, it can be challenging to remain familiar with the adverse events, contraindications, and perioperative recommendations for each agent. Methods: We used FDALabel to identify all Food and Drug Administration–approved immunotherapies indicated for the treatment of breast cancer. We extracted details regarding warnings and precautions, indications, and adverse events from each package insert. Results: We identified nine immunotherapies belonging to three classes: anti-human epidermal growth factor receptor 2 (HER2) agents, anti-programmed cell death protein 1 (PD-1) agents, and anti-trophoblast cell-surface antigen 2 (TROP-2) agents. Cardiotoxicity, including heart failure and cardiomyopathy, was common among those receiving anti-HER2 agents, and hypothyroidism was common among patients receiving the anti-PD-1 agent. The anti-TROP-2 agent was associated with diarrhea and neutropenia. Given the adverse event profile for each drug, we recommend preoperative evaluation components, including transthoracic echocardiography, liver function tests, and thyroid panels. We also indicate here which immunotherapies raise concern for venous thromboembolism, hematoma, and infection. Conclusions: Using data from clinical trials, we recommend a preoperative evaluation tailored to the immunotherapeutic regimen of individual patients.","PeriodicalId":516238,"journal":{"name":"Plastic & Reconstructive Surgery-Global Open","volume":"16 6","pages":"e5915"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141409627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Allergic Reaction in Contrast-enhanced Ultrasound Lymphography for Lymphovenous Bypass Surgery 用于淋巴管旁路手术的对比增强超声淋巴造影术中的过敏反应

Plastic & Reconstructive Surgery-Global Open Pub Date : 2024-06-01 DOI: 10.1097/GOX.0000000000005908

Jess D. Rames, Nho V. Tran, G. Hesley, Vahe Fahradyan, Christine U. Lee

{"title":"An Allergic Reaction in Contrast-enhanced Ultrasound Lymphography for Lymphovenous Bypass Surgery","authors":"Jess D. Rames, Nho V. Tran, G. Hesley, Vahe Fahradyan, Christine U. Lee","doi":"10.1097/GOX.0000000000005908","DOIUrl":"https://doi.org/10.1097/GOX.0000000000005908","url":null,"abstract":"Summary: Lymphedema following oncologic intervention can cause significant lifelong morbidity for patients in whom conservative management fails. The associated swelling, discomfort, pain, and recurrent cellulitis greatly diminish quality of life. Surgical procedures, including suction-assisted lipectomy, lymphovenous anastomosis (LVA), and vascularized lymph node transfers, show effectiveness in both volume reduction in affected extremities and symptom relief. However, the success of procedures like LVA is dependent on effective preoperative lymphatic mapping to identify suitable vessels for anastomosis. Traditional superficial lymphatic mapping uses near infrared fluorescence indocyanine green (ICG) imaging. Moreover, recent advances in contrast-enhanced ultrasound (CEUS) lymphography increased lymphovenous bypass target identification for LVA in the extremities.7 CEUS lymphography uses microbubbles as a contrast-enhancing agent injected intradermally into the affected extremity with subsequent identification of superficial collecting lymphatic vessels using ultrasound. Although a recent report noted an uptick in severe and critical adverse drug reactions to an ultrasound contrast agent injected intravenously in stress echocardiography, adverse drug reactions associated with ultrasound contrast-enhancing agents in body ultrasound are rare. The safety profile and potential complications from CEUS lymphography in the lymphedema population have yet to be fully characterized. In this case report, the authors present the first cutaneous adverse drug event following a secondary exposure to the contrast used for CEUS imaging. Mechanisms and justifications for an immune-mediated process are explored, and a review of similar manifestations in other related contrast applications is discussed.","PeriodicalId":516238,"journal":{"name":"Plastic & Reconstructive Surgery-Global Open","volume":"74 S7","pages":"e5908"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141391014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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