Manuel Sánchez-Gutiérrez, Itziar Hernández-Martínez, Eduardo Osiris Madrigal-Santillán, Kevin Francisco Flores-Elizalde, J. A. Izquierdo-Vega
{"title":"Effect of fluoride-induced testicular alteration in rats fed a high-fat diet","authors":"Manuel Sánchez-Gutiérrez, Itziar Hernández-Martínez, Eduardo Osiris Madrigal-Santillán, Kevin Francisco Flores-Elizalde, J. A. Izquierdo-Vega","doi":"10.5620/eaht.2024023","DOIUrl":"https://doi.org/10.5620/eaht.2024023","url":null,"abstract":"Previous research on the well-known environmental pollutant fluoride has demonstrated that fluoride exposure can lead to oxidative stress-related male infertility. Obesity is another public health issue that has a detrimental impact on male fertility. Previously, findings on fluoride toxicity in high-fat diet (HFD) conditions associated with oxidative stress have been evidenced. This study aimed to evaluate the impact of subchronic fluoride exposure (5 mg/kg) plus a HFD on testicular alteration in Wistar rats. Animals were divided into four groups (control, HFD, fluoride, and fluoride 5 mg/kg plus HFD). The HFD contained a 50% kcal increase in fat (saturated fat), after 90 days of co-exposure to fluoride plus HFD, the animals showed a significant decrease in the adiposity index. The co-exposed group showed oxidative damage assessed through decreased glutathione (GSH) concentration (p < 0.0001), increased concentrations of malondialdehyde (MDA) (p < 0.0001), and the oxidation of proteins (p < 0.0001) vs the control group. Finally, testicular histology exhibited a reduction in spermatogonia and spermatocytes. The results of the study indicate that under these conditions, subchronic co-exposure to fluoride under HFD conditions could protect against the accumulation of epididymal fat, however, oxidative alteration at the testicular level is maintained.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141674420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Yahaya, Mutiyat Kehinde Adewale, Abdulgafar Bala Ibrahim, Baliqees Abdulkadir, Chikelu Chinelo Emmanuela, Adamu Zainab Fari, Asiya Koko Attahiru, Joseph Dahali Wanda
{"title":"Abundance, characterization, and health risk evaluation of microplastics in borehole water in Birnin Kebbi, Nigeria","authors":"T. Yahaya, Mutiyat Kehinde Adewale, Abdulgafar Bala Ibrahim, Baliqees Abdulkadir, Chikelu Chinelo Emmanuela, Adamu Zainab Fari, Asiya Koko Attahiru, Joseph Dahali Wanda","doi":"10.5620/eaht.2024017","DOIUrl":"https://doi.org/10.5620/eaht.2024017","url":null,"abstract":"Microplastic pollution has become a global menace, and water, being a major \"sink\" for pollutants, represents a significant source of human exposure. This study aimed to assess the safety of borehole water in Birnin Kebbi, Nigeria, specifically concerning microplastic pollution. Water samples were collected from boreholes in selected areas, including Bayan Kara, Malali, Rafin Atiku, Aliero Quarters, GwadanGaji, FUBK Takeoff Site, Kalgo Market, and Tarasa. Microplastics were extracted from the water samples through filtration using glass fiber filter papers, and were subsequently subjected to spectroscopy and microscopy to determine concentrations, shapes, and polymer types. Health risks associated with the microplastics were also calculated. The results revealed that the samples from Tarasa exhibited the highest concentrations of microplastics (96.967 particles/L), followed by Bayan Kara (92.70 particles/L), Rafin Atiku (92.33 particles/L), GwadanGwaji (92.30 particles/L), FUBK Takeoff Site (91.07 particles/L), Aliero Quarters (90.43 particles/L), Kalgo Market (88.00 particles/L), and Malali (86.40 particles/L). The most dominant shape was fibers (73 %), followed by fragments (16 %), foams (6 %), and filaments (5 %). Polyethylene and polyamide, in that order, were the most dominant polymers, while polystyrene was the least common. The majority of risk scores were classified as III. It can be inferred from the results that microplastic pollution in borehole water poses a health hazard in the city. Consumers of borehole water in the studied areas are advised to treat the water before consumption to mitigate potential health risks.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":" 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141371174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heavy metals pollution and ecological risk assessment around artisanal gold Mmines in Zamfara, Nigeria","authors":"Bate Garba Barde, Adeniyi Olanrewaju Adeleye, Amoo Afeez Oladeji, Yunana Bitrus Duhu","doi":"10.5620/eaht.2024016","DOIUrl":"https://doi.org/10.5620/eaht.2024016","url":null,"abstract":"Heavy metals pollution and potential ecological risk index were assessed in artisanal gold mining areas of Zamfara state, Nigeria. Soil samples were collected from three mines namely Kwali (05°45.49'E–11°59.66'N), Duke (06°19.56'E–12°21.45'N) and Maraba (06°22.43'E–12°20.26'N) while a non–mining area; Kadauri (06°08.71'E–12°13.56'N) was also chosen as a control. Samples were analysed using atomic absorption spectrophotometer and the results obtained showed that; the most abundant metal was Pb (148.59 mg/kg) in Kwali and the least was Ni (1.25 mg/kg) in Kadauri while the metals generally occurred in the order; Pb > Fe > Au > Al > Zn followed by other metals in an unspecified manner. All metal concentrations differed significantly (P<0.05) across sampling stations except Mn and Zn and they were all above the WHO limit which portrays a health risk. A strong positive correlation was found between metal pairs with r ≥ 0.5 (*p<0.05) in about 70% of them indicating commonality of source. Pb, Cd, Al and Au had contamination factors > 1in all sampling locations indicating increment in their concentrations above the pre–anthropogenic activities reference levels. Geoaccumulation index showed concentrations above background values of Pb, Cd, Al and Au while potential ecological risk index was highest (782.79) in Kwali and lowest (142.15) in Kadauri. Two principal components accounted for about 99.64% of the total variation in metals concentration with PC1 (95.21%) and PC2 (4.43%). This study showed the influence of artisanal gold mining on heavy metals concentration and suggested regulation of these practices.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141371909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chinemerem C. Nwaozuzu, Stephen O. Abah, K. Patrick-Iwuanyanwu
{"title":"Polycyclic aromatic hydrocarbon in community drinking water, Nsisioken, Nigeria: Source and health risk assessment","authors":"Chinemerem C. Nwaozuzu, Stephen O. Abah, K. Patrick-Iwuanyanwu","doi":"10.5620/eaht.2024015","DOIUrl":"https://doi.org/10.5620/eaht.2024015","url":null,"abstract":"In 2011, the United Nations Environment Programme discovered high levels of hydrocarbon pollution in drinking water wells in Nsisioken Agbi Ogale Rivers State, Nigeria. However, the level of polycyclic aromatic hydrocarbons (PAHs) in the same community's water supply was unknown. A comprehensive study of PAHs in three household dug wells and three boreholes was conducted using Agilent 7890B gas chromatography and 5975A mass spectrometry. The detected PAHs were mainly 4 - 5 ringed PAHs, such as Chrysene, Fluoranthene, Pyrene, Benzo[a]anthracene, and Benzo[b]fluoranthene. The total mean concentration was 5.8 ± 2.3 μg/L, with values ranging from not detected in borehole 3 to 8.0 μg/L at well 2. Source identification analysis suggested that the PAHs originated from fuel and biomass combustion. The incremental lifetime cancer risk for children and adults due to groundwater ingestion and skin contact ranged from ND to 7.448 × 10−3 and ND to 1.83 × 10−3 respectively. The Risk index (RI) values from ingestion and dermal routes were 1.5 ×10-2 and 2.4 × 10-2, indicating high risk of cancer. The hazard quotient for the two non-carcinogenic PAHs was greater than 1, indicating high toxicity. The PAH concentrations exceeded the maximum contamination limits set by the World Health Organization and the U.S. environmental Protection Agency, highlighting potential health risks associated with water use in the community. Authorities should provide a safe alternative water source for the community.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141371307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric Crosbie, Sara Perez, Johnny Hartman, Lisa Sheretz, Neil E. Klepeis
{"title":"Measuring air quality in smoking and nonsmoking areas of Nevada casinos (Reno/Sparks): Potential exposure of minors to secondhand smoke","authors":"Eric Crosbie, Sara Perez, Johnny Hartman, Lisa Sheretz, Neil E. Klepeis","doi":"10.5620/eaht.2024014","DOIUrl":"https://doi.org/10.5620/eaht.2024014","url":null,"abstract":"To understand the potential exposure to tobacco smoke in Washoe County (Reno/Sparks), Nevada casinos by measuring air quality in smoking areas relative to non-smoking/non-gaming areas in which minors may be present. To act as a pilot study in community-based health research and policy campaigns by evaluating low-cost air monitors to measure personal secondhand smoke (SHS) exposure. We used customized mobile apps, AtmoTube PRO Air Monitors, and hand clickers to measure the timing and minute-by-minute levels of PM2.5 (a tobacco smoke marker). The app was used to record the number of smokers, minors, and total patrons associated with ~10-minute sequential time periods in standardized casino locations, including outdoor areas, slots, tables, restaurants, bars/lounges, arcades, among others. Between April and May 2022, we successfully visited 14 casinos and 18 distinct types of indoor casino locations. We found high PM2.5 peaks in casino locations even with zero, or a low percentage of, observed active smokers, including in both gaming/non-gaming areas. Indoor areas, regardless of smoking/non-smoking areas, consistently had higher PM2.5 levels than outdoor background levels. Indoor locations had median PM2.5 levels up to 18 times higher than the lowest outdoor background levels. Minors were present throughout all casino locations, and thus were likely exposed to elevated PM2.5 levels. Potential PM2.5 exposures due to smoking can be high regardless of ventilation systems. Small proportions of smokers in a location can lead to high levels of exposure. Establishing comprehensive smoke-free casinos is the only way to protect against SHS harms.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":"350 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140698298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Osuala, Olamide Florence Humphrey, M. Igwo-Ezikpe, Arnold Godfrey Udoh, Iyanuoluwa Adegbuyi, Mojeed Fasasi, Precious Agada, Azeemah Jimoh, Olufunke Okubamowo
{"title":"Occurrence and seasonal variation of organochlorine pesticides in selected vegetable farmlands in Lagos State, Nigeria","authors":"F. Osuala, Olamide Florence Humphrey, M. Igwo-Ezikpe, Arnold Godfrey Udoh, Iyanuoluwa Adegbuyi, Mojeed Fasasi, Precious Agada, Azeemah Jimoh, Olufunke Okubamowo","doi":"10.5620/eaht.2024013","DOIUrl":"https://doi.org/10.5620/eaht.2024013","url":null,"abstract":"Pest infestation in crop production have increased farmers' interest in pesticides use with short and long term consequences. This study investigated the occurrence and seasonal variations of organochlorine pesticide residues in vegetable farms in selected areas of Lagos State. Non carcinogenic and carcinogenic risk assessment was also evaluated. Soil samples were collected during the wet and dry seasons at soil depth of 0-30 cm. Gas chromatography coupled with an Agilent mass spectrometer was used to analyse organochlorine residues (alpha-lindane,lindane, delta.-lindane, aldrin, heptachlor epoxide, alpha.-endosulfan, p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE), endrin, endosulfan, m,p'-dichlorodiphenyldichloroethane (m,p'-DDD), endosulfan sulfate, o,p'-dichlorodiphenyltrichloroethane (o,p'-DDT) and endrin ketone) in soil. Heptachlor epoxide showed maximum concentration of 43.03 mg/kg in Station 19 in Western zone during the dry season while m,p'-DDD and endosulfan had minimum value of 0.004 mg/kg in Station 2 and Station 5 respectively during the wet season in the Far eastern zone. The concentrations of organochlorine residues were intermediate in the Eastern zone in both seasons. There was significant (p < 0.05) increase in dry season concentrations when compared to wet season. The risk assessment indicated Hazard Quotient (HQ) > 1 for non-cancer risk and cancer risk > 10-6. Thus a need for stringent monitoring programs for pesticides.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":"64 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140698903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benzene: A critical review on measurement methodology, certified reference material, exposure limits with its impact on human health and mitigation strategies","authors":"Poonam Kumari, D. Soni, Shankar G. Aggarwal","doi":"10.5620/eaht.2024012","DOIUrl":"https://doi.org/10.5620/eaht.2024012","url":null,"abstract":"Benzene is a carcinogenic pollutant with significant emission sources present in the atmosphere. The need for accurate and precise measurement of benzene in the atmosphere has become increasingly evident due to its toxicity and the adverse health effects associated with exposure to different concentrations. Certified reference material (CRM) is essential to establish the traceability of measurement results. The present review compiles the available national and international measurement methods, certified reference materials (CRMs) for benzene and the limit of benzene in fuel composition (v/v) worldwide. Overall, the review indicates the benzene level in the atmosphere and the resulting impacts on the environment and human health, which frequently exceed the exposure limits of different environment regulatory agencies. An extensive literature review was conducted to gather information on monitoring and analysis methods for benzene, revealing that the most preferred method, i.e. Gas Chromatography- Flame Ionization Detector and Mass Spectrometry, is neither cost-effective nor suitable for real-time continuous monitoring. By analysing existing literature and studies, this review will shed light on the understanding of the importance of benzene pollution monitoring in ambient air and its implications for public health. Additionally, it will reflect the mitigation strategies applied by regulators & need for future revisions of air quality guidelines.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140740966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bashir Olasunkanmi Ayinde, Muhammed Rabiu Musa, Abdul-Afeez Olakunle Ayinde
{"title":"Application of machine learning models and landsat 8 data for estimating seasonal pm 2.5 concentrations","authors":"Bashir Olasunkanmi Ayinde, Muhammed Rabiu Musa, Abdul-Afeez Olakunle Ayinde","doi":"10.5620/eaht.2024011","DOIUrl":"https://doi.org/10.5620/eaht.2024011","url":null,"abstract":"Air pollution is a significant global challenge that affects many cities. In Europe, Bosnia and Herzegovina (BiH) are among the most highly polluted and are mainly affected by air pollution. In this study, we integrate open-source landsat 8 remote sensing products, topographical data, and the limited ground truth PM2.5 data to spatially predict the air quality level across different seasons in Tuzla Canton, BiH by adopting three pre-existing machine learning models, namely XGBoost, K-Nearest Neighbour (KNN) and Naive Bayes (NB). These classification models were implemented based on landsat 8 bands, environmental-derived indices, and topographical variables generated for the study area. Based on the predicted results, the XGBoost model exhibited the highest overall accuracy across all seasons. The predicted model results were used to generate spatial air quality maps. Based on the classification maps, the PM2.5 air quality level predicted for Tuzla Canton in the Winter Season is very unhealthy. The findings conclude that the PM2.5 air quality concentration in Tuzla Canton is relatively unsatisfactory and requires urgent intervention by the government to prevent further deterioration of air quality in Tuzla and other affected cantons in BiH.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":"114 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140379175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Azizah, Ahmad Fariz Hj Mohamed, L. Sulistyorini, Shinta Arta Mulia, Novi Dian Arfiani, Ariska Rahmawati
{"title":"Analysis of waste management effect on the climate related disease in Larangan Village, Sidoarjo","authors":"R. Azizah, Ahmad Fariz Hj Mohamed, L. Sulistyorini, Shinta Arta Mulia, Novi Dian Arfiani, Ariska Rahmawati","doi":"10.5620/eaht.2024010","DOIUrl":"https://doi.org/10.5620/eaht.2024010","url":null,"abstract":"The repercussions of climate change have profound implications for human health, leading to the emergence of climate-related diseases. Recognizing this, the Ministry of Environment and Forestry in Indonesia has established the Climate Village Program to tackle and mitigate the impact of climate change. Despite the implementation of this program, Larangan Village in Candi Sub-district, Sidoarjo Regency, continues to struggle with cases of climate-related diseases. This research aims to assess the impact of waste management on the prevalence of climate-related diseases in Larangan Village. Using a quantitative, analytical, observational approach with a cross-sectional design, the study concentrates on two neighborhoods within Larangan Village. The population consists of 330 families in the 2nd neighborhood (Non-Climate Village Program) and 344 families in the 9th neighborhood (Climate Village Program), with a sample size of 109. The variables under investigation encompass waste management and climate-related diseases. Data collection involves conducting interviews and distributing questionnaires among community members in both neighborhoods. The collected data undergo analysis using Multigroup Analysis SEM PLS with a significance level of 0.05. The findings reveal a significant negative correlation between waste management and climate-related diseases, suggesting that enhanced waste management is linked to a reduced incidence of such diseases in the community.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microplastic pollution in landfill soil: Emerging threats the environmental and public health","authors":"Okky Assetya Pratiwi, U. Achmadi, Rico Kurniawan","doi":"10.5620/eaht.2024009","DOIUrl":"https://doi.org/10.5620/eaht.2024009","url":null,"abstract":"Insufficient knowledge about the decomposition of microplastics from plastic waste in landfills hinders community involvement in waste management and sorting, posing a new threat to the environment and public health. The present study identifies, characterizes, and quantifies the microplastics in landfills soil sample to determine the latest threats posed by microplastics in the environment, particularly in landfills that are close to residential areas. This research is a descriptive study, with soil samples taken from six points in landfill site in Depok City. The abundance and shape of microplastics were characterized using a microscope, while the microplastic types were identified using Fourier Transform Infrared Spectroscopy (FTIR). The results showed that the abundance of microplastics in the Depok City landfill soil was 60,111.67 particles/kg, with the largest percentage being fragments at 63 %. FTIR functional group characterization showed the presence of plastic types, such as Polyethylene (PE), Polyvinyl Chloride (PVC), Polystyrene (PS), Polypropylene (PP), Polyethylene Terephthalate (PET), and Polyamide. The differences in waste types entering the Depok Landfill caused variations in the number, shape, and type of microplastic samples, and this study provides a foundation for mitigating and biodegrading microplastics in the landfill to minimize environmental impact and protect public health.","PeriodicalId":515414,"journal":{"name":"Environmental Analysis Health and Toxicology","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}