Jose-Maria Abellan-Perpiñan, Esther Redondo Margüello, Ángel Gil de Miguel, Iván Sanz Muñoz, Ariadna Diaz-Aguiló, Paloma Palomo, Manel Farré, Daniel Callejo, Marco Pinel, Juan Luis López-Belmonte
{"title":"Cost-effectiveness analysis of influenza vaccination with high-dose vaccine versus standard-dose quadrivalent vaccine in older adults in Spain.","authors":"Jose-Maria Abellan-Perpiñan, Esther Redondo Margüello, Ángel Gil de Miguel, Iván Sanz Muñoz, Ariadna Diaz-Aguiló, Paloma Palomo, Manel Farré, Daniel Callejo, Marco Pinel, Juan Luis López-Belmonte","doi":"10.1007/s10198-026-01894-8","DOIUrl":"10.1007/s10198-026-01894-8","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Influenza is a widespread acute respiratory illness which represents a significant public health challenge from both the National Health Service (NHS) and societal perspective, especially in the older adults. The aim of this study was to assess the cost-effectiveness of influenza vaccination with a high-dose quadrivalent vaccine (HD-QIV) versus a standard dose quadrivalent vaccine (SD-QIV) in the older adults in Spain.</p><p><strong>Methods: </strong>We assessed the public health and economic benefits of various alternatives using a decision-tree model. This model considered factors such as influenza cases, visits to general practitioners (GP), emergency department (ED) visits, hospitalizations due to cardiorespiratory events, and influenza-related mortality. To address uncertainties deriving from both epidemiological and economic sources, we conducted deterministic and probabilistic sensitivity analyses.</p><p><strong>Results: </strong>From a societal perspective, HD-QIV compared to SD-QIV prevented during an influenza season 54,039 influenza cases, 7,733 GP consultations, 1,585 ED visits, 30,772 episodes of hospitalization due to cardiorespiratory events over a single influenza season and 1,203 deaths when vaccinating adults ≥ 65 years old in Spain, resulting in 14,316 LYs and 12,545 QALYs gained over a lifetime horizon. The reduction in health outcomes outweighed the increase in vaccination costs, translating to a reduction in total costs with HD-QIV compared to SD-QIV. Therefore, vaccinating older adults in Spain with HD-QIV instead of SD-QIV was a dominant strategy when evaluating hospitalizations due to cardiorespiratory events. HD-QIV remained dominant from an NHS perspective. Sensitivity analyses confirmed the robustness of the model.</p><p><strong>Conclusions: </strong>This analysis showed that vaccinating older adults in Spain with HD-QIV instead of SD-QIV would reduce cases of influenza, GP and ED visits, hospitalizations, deaths, and associated costs, and thus it should be the strategy of choice in a situation of budgetary constraints from either a societal or an NHS perspective.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1497-1508"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147349679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cash-for-care and its impact on older adults' informal and formal long-term care use: evidence from continental European countries.","authors":"Viktoria Szenkurök","doi":"10.1007/s10198-026-01901-y","DOIUrl":"10.1007/s10198-026-01901-y","url":null,"abstract":"","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1525-1538"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefan A Lipman, David R de Buisonjé, Koen van der Swaluw
{"title":"Promoting healthy behaviour with financial incentives: three challenges and solutions for large scale implementation.","authors":"Stefan A Lipman, David R de Buisonjé, Koen van der Swaluw","doi":"10.1007/s10198-025-01893-1","DOIUrl":"10.1007/s10198-025-01893-1","url":null,"abstract":"<p><p>Financial incentives are a promising intervention to promote healthier behaviours and potentially reduce health inequalities. Despite robust evidence supporting their effectiveness in encouraging actions such as smoking cessation, increased physical activity, and improved diet, large-scale implementation of financial incentives in Europe remains limited. This perspective identifies three key challenges impeding their broader use: (1) difficulties in reaching the populations most in need, (2) short-lived behavioural effects after removal of the incentives, and (3) uncertainty about sustainable and equitable funding. Drawing on interdisciplinary evidence, we explore potential solutions such as tailored incentive design, strategies to prolong behavioural change (e.g. intermittent reinforcement or dynamic phase-outs), and the development of public or private funding models. We argue that while financial incentives should not replace structural health policy interventions, they can be a powerful complementary tool. A coordinated research agenda is needed to inform scalable and effective implementation.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1379-1386"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146114939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea N Natsky, Ching Li Chai-Coetzer, Andrew Vakulin, Billingsley Kaambwa
{"title":"Predicting EuroQol (EQ-5D-5 L) health state utilities from functional outcomes of sleep questionnaire (FOSQ-10) scores.","authors":"Andrea N Natsky, Ching Li Chai-Coetzer, Andrew Vakulin, Billingsley Kaambwa","doi":"10.1007/s10198-025-01885-1","DOIUrl":"10.1007/s10198-025-01885-1","url":null,"abstract":"","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1387-1402"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complex intervention for MS patients in Germany - can it be cost-saving for the society?","authors":"Markus Krohn, Susan Raths, Steffen Fleßa","doi":"10.1007/s10198-026-01907-6","DOIUrl":"10.1007/s10198-026-01907-6","url":null,"abstract":"","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1549-1561"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Idrissa Ouedraogo, Windkouni Haoua Eugenie Maïga, Robert Gillanders, Doris Aja-Eke
{"title":"Health sector corruption and access to healthcare in Africa.","authors":"Idrissa Ouedraogo, Windkouni Haoua Eugenie Maïga, Robert Gillanders, Doris Aja-Eke","doi":"10.1007/s10198-026-01896-6","DOIUrl":"10.1007/s10198-026-01896-6","url":null,"abstract":"","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1509-1523"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aarushi Dhingra, Brenda Gannon, Terence C Cheng, Luke Connelly, Gita Mishra
{"title":"Healthcare cost for non-hospital services and pharmaceuticals among breast cancer survivors: an event study.","authors":"Aarushi Dhingra, Brenda Gannon, Terence C Cheng, Luke Connelly, Gita Mishra","doi":"10.1007/s10198-025-01889-x","DOIUrl":"10.1007/s10198-025-01889-x","url":null,"abstract":"<p><p>Breast cancer survivors require continuing long-term care, which leads to substantial resource use and subsequently increased healthcare costs (HC), having an impact on both the individual and society. This paper aims to investigate the impact of a breast cancer diagnosis on monthly HC and out-of-pocket (OOP) costs among survivors. We apply an event study methodology using a two-part fixed-effect model. Data from the Australian Longitudinal Study of Women's Health (2002-2017) is utilised, which is linked to extensive high-frequency administrative records from the Medicare Benefits Schedule, the Pharmaceutical Benefits Scheme, the Australian Cancer Database and the National Death Index. The findings reveal that a diagnosis leads to a persistent and substantial increase in total HC and OOP costs, with the largest increases occurring in the first six months. The effects' duration and magnitude vary by the type of healthcare service and pharmaceuticals.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1403-1435"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mobile money and households' ability to respond to health shocks in Africa: Evidence from Madagascar.","authors":"Gbêtondji Melaine Armel Nonvide","doi":"10.1007/s10198-025-01888-y","DOIUrl":"10.1007/s10198-025-01888-y","url":null,"abstract":"<p><p>Promoting the use of mobile money seems to be an important way of improving financial inclusion and households ability to cope with health shocks. This study aims to analyze the impact of mobile money usage on households ability to respond to health shocks in Madagascar. We also investigated the differential impact for disadvantaged groups such as female, less educated and rural people. FinScope database on financial inclusion is used. Employing an instrumental probit model, the results reveal that the use of mobile money increases households' ability to respond to health shocks by about 44.8%. The mains coping mechanisms include used of savings and assistance from friends/family. Results also reveal that the use of mobile money favors households in urban area compared to those in rural area. Women benefited more compared to men. Overall, these findings could inform policy makers on how to improve financial inclusion for disadvantaged groups and reduce vulnerability to health shocks in Africa.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1479-1496"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Dynamics of Hospitalization Expenses and Health Insurance: A Finite Mixture Model Approach.","authors":"Shakeel Ahmed","doi":"10.1007/s10198-026-01906-7","DOIUrl":"10.1007/s10198-026-01906-7","url":null,"abstract":"","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1539-1548"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are there longer-term costs of informal care? Understanding post-care wellbeing and labour market participation outcomes.","authors":"Wai-Man Liu, Emma Schultz, Aaron Bruhn","doi":"10.1007/s10198-025-01850-y","DOIUrl":"10.1007/s10198-025-01850-y","url":null,"abstract":"<p><p>While a substantial body of empirical research documents the negative wellbeing and labour force participation effects of transitioning into and maintaining informal care roles, studies of transitions out of caregiving are small in number and present conflicting results. We contend that these conflicting results reflect differences in sample selection and methodological approaches. As such, we implement a novel research design known as staggered difference-in-differences to account for heterogeneities in carers' transition dates, caregiving intensity, and demographic and socio-economic characteristics to deliver robust evidence on their post-transition wellbeing and labour force participation outcomes. Our sample is drawn from Waves 5 to 18 of the Household, Income and Labour Dynamics in Australia Survey, Australia's largest longitudinal household survey, and comprises 6,090 respondent-Wave-level observations from respondents who transitioned out of carer roles. We find that respondents who previously devoted at least 10 hours per week to care enjoy significantly better mental health, emotional wellbeing and social functioning than those with ongoing carer duties. These benefits are immediate and generally persist for years after transitioning out of carer roles. Labour market participation outcomes follow a similar pattern: both employment rates and hours worked rise sharply upon exit and remain elevated. Our results also underscore the importance of using care intensity measures that accurately reflect the burden of caregiving, specifically, time- rather than role-based metrics.</p>","PeriodicalId":51416,"journal":{"name":"European Journal of Health Economics","volume":" ","pages":"1437-1451"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146094764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}