Women Pub Date : 2024-04-08 DOI: 10.3390/women4020009

Anna Targonskaya, Karolina Wieczorek, Katherine Maslowski

{"title":"Endogenous Hormones and Cognitive Decline in Women: Unveiling the Complex Interplay","authors":"Anna Targonskaya, Karolina Wieczorek, Katherine Maslowski","doi":"10.3390/women4020009","DOIUrl":"https://doi.org/10.3390/women4020009","url":null,"abstract":"This narrative review delves into the area of endogenous hormones and their impact on cognitive function, with a focus on women transitioning through perimenopause. While artificial intelligence technologies have revolutionized cognitive research, the inclusion of hormonal biomarkers remains sparse. The review synthesizes findings from diverse studies exploring the relationships between estrogen, progesterone, testosterone, other sex hormones, and cognitive performance. The research question explores the potential for monitoring endogenous hormonal levels during perimenopause to predict cognitive decline and inform preventive strategies. An analysis of relevant studies reveals a complex relationship, with varying impacts on cognitive domains. Thus, high E2 levels correlate positively with verbal memory and retrieval efficiency, contrasting with lower levels associated with enhanced visual memory, and testosterone shows positive links to verbal fluency. The limitations of existing research, including heterogeneous methodologies and a dearth of premenopausal representation, emphasize the necessity for future studies. To achieve this objective, it is important to leverage data from studies implementing standardized methodologies for tracking endogenous hormonal levels while accounting for cycle phases and menopausal transition stages. Additionally, employing standardized assessments for cognitive decline and analyzing extensive datasets derived from real-world sources, such as hospital or outpatient clinic chains, and digital apps, is crucial.","PeriodicalId":512463,"journal":{"name":"Women","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140728840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Benefits and Barriers of Providing Non-Pharmacological Pain Relief to Women in Labour during COVID-19: A Qualitative Study of Midwives in South Africa 在 COVID-19 期间为产妇提供非药物止痛的好处和障碍：对南非助产士的定性研究

Women Pub Date : 2024-03-19 DOI: 10.3390/women4010008

Limakatso Elizabeth Parkies, D. Murray, U. B. Okafor

{"title":"The Benefits and Barriers of Providing Non-Pharmacological Pain Relief to Women in Labour during COVID-19: A Qualitative Study of Midwives in South Africa","authors":"Limakatso Elizabeth Parkies, D. Murray, U. B. Okafor","doi":"10.3390/women4010008","DOIUrl":"https://doi.org/10.3390/women4010008","url":null,"abstract":"Pregnancy is an exceptional event in a woman’s life. As a result of the intense pain associated with childbirth, women require encouragement and support during this crucial phase. Midwives play a crucial role in the maternal care paradigm, managing labour pain alongside ensuring the mother and baby’s safety during the labour process. This study explored midwives’ perspectives concerning the utilisation and barriers of non-pharmacological labour pain reduction methods during COVID-19 in Matjhabeng Municipality hospitals in South Africa’s Free State Province. Ten midwives participated in a semi-structured interview wherein the audio was recorded and transcribed verbatim. The data were analysed using Tesch’s approach for open-coding data analysis. Midwives’ experiences with non-pharmacological therapeutic options for relieving labour pain were varied. They used mobilisation techniques, warm bathing, deep breathing exercises, back massaging, and psychological support. Midwives affirmed that non-pharmacological labour pain interventions were poorly implemented because of staff shortages, heavy workload, and COVID-19 regulations at the time. In efforts to address the obstacles in managing labour pain and alleviate the pain of women during labour, midwives recommended the provision of education and advocacy, the employment of additional midwives and auxiliary staff, and improvement in hospital infrastructure. Due to staff shortages, heavy workloads, and COVID-19 restrictions that limit birth companions, non-pharmacological pain reduction methods are not properly implemented. Health education; employing additional midwives, professional doulas, and students; and improving health infrastructure are midwives’ concerns. Prioritising midwife training in non-pharmacological labour pain management is crucial for delivering the best possible care during childbirth.","PeriodicalId":512463,"journal":{"name":"Women","volume":"43 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140228967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Increase in Prominent Probiotics Represents the Major Change in the Gut Microbiota in Morbidly Obese Female Patients upon Bariatric Surgery 肥胖症女性患者接受减肥手术后，肠道微生物群的主要变化是主要益生菌的增加

Women Pub Date : 2024-03-18 DOI: 10.3390/women4010007

Ann-Kathrin Kissmann, Frederike Paß, Hans-Maximilian Ruzicka, Isabel Dorst, Kai R. Stieger, Tanja Weil, Adrian Gihring, Leonard Elad, U. Knippschild, F. Rosenau

{"title":"An Increase in Prominent Probiotics Represents the Major Change in the Gut Microbiota in Morbidly Obese Female Patients upon Bariatric Surgery","authors":"Ann-Kathrin Kissmann, Frederike Paß, Hans-Maximilian Ruzicka, Isabel Dorst, Kai R. Stieger, Tanja Weil, Adrian Gihring, Leonard Elad, U. Knippschild, F. Rosenau","doi":"10.3390/women4010007","DOIUrl":"https://doi.org/10.3390/women4010007","url":null,"abstract":"The global increase in obesity carries inherent health implications, with an increased BMI being a known risk factor for diseases such as type 2 diabetes, cardiovascular diseases, or different cancer types. The long-term effectiveness of diet therapy in addressing morbid obesity is extremely limited, with no adequate pharmaceutical agents available as treatment options, resulting in bariatric surgery being the only viable option to achieve and maintain significant long-term weight loss. Something that plays an important role in overall human health is the gut microbiome and its complex composition, which is usually altered and reduced in complexity/diversity in severely obese patients. In this study, the influence of bariatric surgery and the resulting weight loss on the gut microbiome composition of twelve morbidly obese (BMI ≥ 40) adult female central European patients was investigated by comparing the relative abundances of the major microbial phyla Actinobacteria, Bacteroidetes, Firmicutes, and Proteobacteria pre- and post-surgery. We also aimed to give insight into the major changes in individual prominent and promising future probiotic bacteria characterized by an overall increase in abundance accompanied by a switch of enterotypes. Identifying specific microbial alterations associated with successful weight-loss outcomes may contribute to the development of future therapeutic interventions by supplementation with next-generation probiotics.","PeriodicalId":512463,"journal":{"name":"Women","volume":"46 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140231675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Perceptions of Cesarean Sections among Postpartum Women in Nigeria: A Qualitative Study 探索尼日利亚产后妇女对剖腹产的看法：定性研究

Women Pub Date : 2024-03-15 DOI: 10.3390/women4010006

T. O. Michael, R. D. Agbana, Kammila Naidoo

{"title":"Exploring Perceptions of Cesarean Sections among Postpartum Women in Nigeria: A Qualitative Study","authors":"T. O. Michael, R. D. Agbana, Kammila Naidoo","doi":"10.3390/women4010006","DOIUrl":"https://doi.org/10.3390/women4010006","url":null,"abstract":"Cesarean sections have become increasingly common globally, including in Nigeria. This qualitative study explores the perceptions and experiences of postpartum women who underwent cesarean sections within the distinct contexts of Ibadan in Oyo State, Nigeria. In-depth interviews and focus group discussions were conducted with 24 postpartum women in selected health facilities in urban and rural areas. A diverse sample was purposively selected to capture a range of experiences based on age, residence, education, and cultural backgrounds. Thematic analysis was employed to identify patterns and themes within the data. The findings revealed diverse emotional responses among participants, ranging from relief and gratitude to disappointment and feelings of loss for not experiencing a vaginal birth. Societal pressures and cultural expectations played a significant role in influencing women’s perceptions and experiences of cesarean sections. Future childbirth preferences and support systems, including healthcare provider–patient relationships and community support, were identified as crucial factors impacting postoperative recovery. This study contributes to the understanding of women’s perceptions of cesarean sections within the local context of Ibadan, Nigeria. The findings underscore the importance of culturally sensitive healthcare practices, clear communication, and support systems to enhance the birthing experiences of women undergoing cesarean sections.","PeriodicalId":512463,"journal":{"name":"Women","volume":"21 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140240422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

History of Human Papilloma Virus Vaccination with a Focus on Italy 人类乳头瘤病毒疫苗接种历史，聚焦意大利

Women Pub Date : 2024-02-06 DOI: 10.3390/women4010004

Giovanni Gabutti, Matilde Ogliastro

引用次数: 0

History of Human Papilloma Virus Vaccination with a Focus on Italy 人类乳头瘤病毒疫苗接种历史，聚焦意大利

Women Pub Date : 2024-02-06 DOI: 10.3390/women4010004

Giovanni Gabutti, Matilde Ogliastro

引用次数: 0

Navigating the Maze: Facilitators and Barriers to Substance Use Treatment for Pregnant and Parenting Women in Mississippi 迷宫导航：密西西比州孕妇和养育子女妇女接受药物使用治疗的促进因素和障碍

Women Pub Date : 2024-02-04 DOI: 10.3390/women4010003

K. Klee, J. Bartkowski, Caroline Newkirk, Jan Dawson, Jonathan Hubanks

引用次数: 0

Navigating the Maze: Facilitators and Barriers to Substance Use Treatment for Pregnant and Parenting Women in Mississippi 迷宫导航：密西西比州孕妇和养育子女妇女接受药物使用治疗的促进因素和障碍

Women Pub Date : 2024-02-04 DOI: 10.3390/women4010003

K. Klee, J. Bartkowski, Caroline Newkirk, Jan Dawson, Jonathan Hubanks

引用次数: 0

Safety and Effectiveness of Naproxen 220 mg + Paracetamol 300 mg + Pamabrom 25 mg Fixed Dose Combination in Women with Premenstrual Syndrome: A Post-Marketing, Open-Label, Uncontrolled, Prospective, Multicenter, Observational Study 萘普生 220 毫克 + 扑热息痛 300 毫克 + 帕马溴 25 毫克固定剂量复方制剂对经前综合征妇女的安全性和有效性：一项上市后、开放标签、非对照、前瞻性、多中心、观察性研究

Women Pub Date : 2024-01-24 DOI: 10.3390/women4010002

Álvaro E. Peña-Jiménez, Omar Benitez-Aguilar, Jesús E. Villegas, Mario González-de la-Parra, Livan Delgado-Roche

{"title":"Safety and Effectiveness of Naproxen 220 mg + Paracetamol 300 mg + Pamabrom 25 mg Fixed Dose Combination in Women with Premenstrual Syndrome: A Post-Marketing, Open-Label, Uncontrolled, Prospective, Multicenter, Observational Study","authors":"Álvaro E. Peña-Jiménez, Omar Benitez-Aguilar, Jesús E. Villegas, Mario González-de la-Parra, Livan Delgado-Roche","doi":"10.3390/women4010002","DOIUrl":"https://doi.org/10.3390/women4010002","url":null,"abstract":"Premenstrual syndrome is characterized by pain and related symptoms that negatively affect women’s quality of life. Our aim was to evaluate the safety and effectiveness of a specific oral fixed dose combination of naproxen 220 mg + paracetamol 300 mg + pamabrom 25 mg in tablet form. A prospective, open-label, multicenter, uncontrolled, observational post-marketing study was conducted from December 2017 to December 2019 consisting of 270 women over 18. The primary outcome was the number and severity of adverse effects. Secondary outcomes were pain intensity, number and intensity of other premenstrual symptoms, and the proportion of patients with a pain score reduction of at least 50%. The mean age of participants was 28.9 ± 8.8 years. We found that 8 women (3%) experienced adverse events, namely headache (5/8), gastritis (2/8) dyspepsia (1/8), diarrhea (1/8), and nausea (1/8). In three of the eight women, the study was discontinued due to adverse effects. Pain intensity was reduced (−4.5, 95%CI; −5, −4, p < 0.001). The proportion of patients with pain reduction of at least 50% was 70.7%. The study results suggest that the combination of drugs used in this formulation is safe and effective for premenstrual symptoms.","PeriodicalId":512463,"journal":{"name":"Women","volume":"52 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139600825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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