M Kaplan, B Akgun, K Demirdag, N Akpolat, S K Kozan, O Cagasar, H Yakar
{"title":"Use of antibiotic - impregnated DuraGen® to reduce the risk of infection in dura repair: an in vitro study.","authors":"M Kaplan, B Akgun, K Demirdag, N Akpolat, S K Kozan, O Cagasar, H Yakar","doi":"10.1055/s-0030-1267246","DOIUrl":"https://doi.org/10.1055/s-0030-1267246","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the efficacy of antibiotic-impregnated DuraGen® in preventing infection when used for repair of dural defects.</p><p><strong>Material and methods: </strong>2 groups of 7 samples were formed. In the first group, normal DuraGen® samples without antibiotic impregnation and in the second group, DuraGen® samples with antibiotic impregnation (30 mg vancomycin) were used. Staphylococcus aureus (ATCC 25923), and Staphylococcus epidermidis (ATCC 12228) were selected for this study. Antimicrobial efficacy was evaluated by counting the number of colonies on and by measuring the diameter of the inhibition zone around the samples.</p><p><strong>Results: </strong>There was no zone diameter around the normal DuraGen® for the 2 types of bacteria. There was significant bacterial growth (10 (5)) according to the colony count. For antibiotic-impregnated DuraGen®, there was a zone with a mean diameter of 32 mm in the agar with S. aureus and a zone with a mean diameter of 35 mm in the agar with S. epidermidis. Antibiotic-impregnated DuraGen® was quite effective against both microorganisms and there was no bacterial growth according to the bacterial colony count.</p><p><strong>Conclusions: </strong>In our in vitro study, antibiotic-impregnated DuraGen® material significantly inhibited microorganism growth. Our results show that antibiotic-impregnated DuraGen® has the potential to prevent infection.</p>","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 2","pages":"75-7"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0030-1267246","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29691970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Raimund, S Nickel, C Hessler, J Regelsberger, M Westphal, O Heese
{"title":"Non-conventional treatments sought by patients after surgery for intramedullary spinal cord tumors.","authors":"F Raimund, S Nickel, C Hessler, J Regelsberger, M Westphal, O Heese","doi":"10.1055/s-0030-1252009","DOIUrl":"https://doi.org/10.1055/s-0030-1252009","url":null,"abstract":"<p><strong>Objective: </strong>Despite modern microsurgical techniques and interdisciplinary treatment options, intramedullary spinal cord tumors often lead to profound neurological deficits. Some patients may search for non-scientific or unconventional therapeutic options to treat the symptoms induced by the tumor itself or arising from treatment. The extent of non-scientific therapy use, the rationale behind it, and costs of these forms of therapy are unknown.</p><p><strong>Methods: </strong>A questionnaire consisting of 20 questions was sent to 60 patients of a single neurosurgical center who had undergone surgery for an intramedullary spinal cord tumor. A retrospective study was carried out based on this data. Histological findings ranged from ependymoma (52.9%), hemangioblastoma (17.6%), cavernoma (14.7%), astrocytoma (8.8%), oligodendroglioma (2.9%) to ganglioglioma (2.9%). Non-scientific therapy was defined as a method not used in routine clinical practice for the treatment of symptoms induced by intramedullary spinal cord tumors.</p><p><strong>Results: </strong>A total of 38 questionnaires was returned. About 55.3% of the patients claimed to use non-scientific therapies. No significant difference between histological types and the percentage of alternative therapy use was detected. There was a gender difference. One third (non user group) to one fourth (user group) did not feel adequately informed about their disease. The monthly costs for non-scientific therapies ranged from 50 to 500 Euros. The main motive for the use of non-scientific therapies was the wish to try everything possible.</p><p><strong>Conclusion: </strong>In the daily clinical routine, patients' use of non-scientific therapies may be largely overlooked and underestimated. Neurooncologists should be aware of this phenomenon and encourage an open but critical dialogue with their patients.</p>","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 2","pages":"71-4"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0030-1252009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29011425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O M Mueller, C Gaul, Z Katsarava, H C Diener, U Sure, T Gasser
{"title":"Occipital nerve stimulation for the treatment of chronic cluster headache - lessons learned from 18 months experience.","authors":"O M Mueller, C Gaul, Z Katsarava, H C Diener, U Sure, T Gasser","doi":"10.1055/s-0030-1270476","DOIUrl":"https://doi.org/10.1055/s-0030-1270476","url":null,"abstract":"Objective: Patients and Methods: Results: Conclusions:","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 2","pages":"84-9"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0030-1270476","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29778404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Chudy, M Rados, D Ozretic, G Grahovac, K Zarkovic
{"title":"Stereotactically treated giant perivascular spaces in a 13-year-old boy mimicking brain tumor.","authors":"D Chudy, M Rados, D Ozretic, G Grahovac, K Zarkovic","doi":"10.1055/s-0030-1253411","DOIUrl":"https://doi.org/10.1055/s-0030-1253411","url":null,"abstract":"Chudy D et al. Stereotactically Treated Giant Perivascular Spaces ... Cen Eur Neurosurg 2011; 72: 104 – 106 Introduction ▼ Perivascular spaces (PVSs) of the brain, also known as Virchow-Robin spaces, are pia-lined cavities surrounding brain arteries and arterioles as they penetrate into the cerebral tissue [13, 16] . Cystic cavities have fi rst been described in the literature in 1838, as small cavities in the globus pallidus and putamen [2] .","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 2","pages":"104-6"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0030-1253411","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29068769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment to the article: Magnetic resonance spectroscopic imaging for visualization of the infiltration zone of glioma.","authors":"Walter Stummer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 2","pages":"70"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29958934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Eicker, S Sarikaya-Seiwert, A Borkhardt, K Gierga, B Turowski, H-J Heiroth, H-J Steiger, W Stummer
{"title":"ALA-induced porphyrin accumulation in medulloblastoma and its use for fluorescence-guided surgery.","authors":"S Eicker, S Sarikaya-Seiwert, A Borkhardt, K Gierga, B Turowski, H-J Heiroth, H-J Steiger, W Stummer","doi":"10.1055/s-0030-1252010","DOIUrl":"https://doi.org/10.1055/s-0030-1252010","url":null,"abstract":"Eicker S et al. ALA-induced Porphyrin Accumulation in Medulloblastoma ... Cen Eur Neurosurg 2011; 72: 101 – 104 Introduction ▼ Medulloblastoma is the most common malignant brain tumor in children. Most children with this disease are treated in controlled studies to improve survival and advance cure rates [6] . The current treatment includes surgical resection, radiotherapy and chemotherapy. Depending on the classifi cation into standardrisk (age ≥ 4 years, non-metastatic disease, and complete or almost complete tumor resection) and high-risk patients, the treatment options diff er, ranging from postoperative chemotherapy alone [18] , to postoperative chemotherapy and radiotherapy, to stem cell therapy in the case of recurrence [5] . According to the classifi cation, maximum cytoreductive surgery appears to be essential for the effi cacy of adjuvant treatment. All controlled studies so far have aimed at optimizing adjuvant therapies, i. e., chemotherapy and radiotherapy, but to our knowledge none have been devoted to improving surgery. We report the fi rst operation performed with fl uorescence guidance using 5-aminolevulinic acid (ALA) for the resection of medulloblastoma to avoid incomplete tumor resection as a favorable basis for adjuvant therapy [11] .","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 2","pages":"101-3"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0030-1252010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29337987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical management of a ruptured and unruptured distal anterior inferior cerebellar artery aneurysm. Report of 2 cases and review of the literature.","authors":"P Taussky, S Garber, R H Schmidt","doi":"10.1055/s-0030-1268498","DOIUrl":"https://doi.org/10.1055/s-0030-1268498","url":null,"abstract":"Taussky P et al. Surgical Management of a Ruptured ... Cen Eur Neurosurg 2011; 72: 108 – 11","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 2","pages":"108-11"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0030-1268498","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29691925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peroral extrusion of ventriculoperitoneal shunt: a case report and review of the literature.","authors":"R Dua, R Jain","doi":"10.1055/s-0030-1262828","DOIUrl":"https://doi.org/10.1055/s-0030-1262828","url":null,"abstract":"Introduction ▼ Ventriculoperitoneal (VP) shunting is a well-established treatment for hydrocephalus. However, high rates of complications (24 – 47 % ) have been reported and abdominal complications alone account for approximately 25 % of them. The incidence of bowel perforation by a shunt catheter is estimated to be 0.01 – 1 % of all shunting procedures. We present the case of an 8-month-old baby who had peroral extrusion of the distal end of a VP shunt tube. To the best of our knowledge, only 7 such cases have been reported in the literature. This report illustrates the pathology of the perforation with a brief review of management for such cases.","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 2","pages":"107-8"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0030-1262828","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29299862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Neolithic skull from Bölkendorf--evidence for Stone Age neurosurgery?","authors":"J Piek, G Lidke, T Terberger","doi":"10.1055/s-0029-1246133","DOIUrl":"https://doi.org/10.1055/s-0029-1246133","url":null,"abstract":"<p><p>Trephinations in Neolithic people have been described all over the world. The reasons for these operations however are not always clear. In the present paper the authors describe the rare case of a Neolithic skull (dated to 1940 cal BC [calibrated before Christ]) showing the combination of a trephination combined with a healed depressed skull fracture. The authors conclude that at least in some cases such operations have been performed for \"purely\" medical reasons.</p>","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 1","pages":"42-3"},"PeriodicalIF":0.0,"publicationDate":"2011-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0029-1246133","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28771206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Delayed diagnosis of subarachnoid hemorrhage associated with Tako-tsubo cardiomyopathy.","authors":"M Boes, M Henning, H Urbach, M Simon","doi":"10.1055/s-0029-1242758","DOIUrl":"https://doi.org/10.1055/s-0029-1242758","url":null,"abstract":"Boes M et al. Delayed Diagnosis of Subarachnoid Hemorrhage ... Cen Eur Neurosurg 2011; 72: 49 – 51 Delayed Diagnosis of Subarachnoid Hemorrhage Associated with Tako-Tsubo Cardiomyopathy Discussion & Tako-tsubo cardiomyopathy is a recently described acute cardiac syndrome characterized by transient systolic dysfunction. Main criteria for tako-tsubo cardiomyopathy are: a) transient apical and midventricular dyskinesis that extends beyond the distribution of a single coronary artery; b) the absence of signifi cant coronary artery disease or acute plaque rupture on coronary angiography; and c) electrocardiographic evidence of new ST elevation or T-wave inversion. The cause of tako-tsubo cardiomyopathy is unknown, but most cases seem to be related to emotional (33 – 45 % ) and / or physical stress (17 – 22 % ) [10] . There is a strong predominance of postmenopausal women [3] . Precise epidemiological data are not yet available, but serial case studies from Japan revealed a incidence of 1.2 – Introduction & Tako-tsubo cardiomyopathy or “ apical ballooning ” was fi rst described in Japan in 1990 by Satoh et al. [7] The syndrome is characterized by transient left ventricular dysfunction resulting from severe physical or emotional stress. This report describes a 64-year-old woman who underwent CPR (cardiopulmonary resuscitation) because of severe cardiac failure due to tako-tsubo cardiomyopathy. A subarachnoid hemorrhage (SAH) from a ruptured anterior communicating aneurysm was diagnosed as the underlying cause seven days later.","PeriodicalId":51241,"journal":{"name":"Central European Neurosurgery","volume":"72 1","pages":"49-51"},"PeriodicalIF":0.0,"publicationDate":"2011-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0029-1242758","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29051644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}