Henry Mauricio Parada-Gereda PT MSc , Daniel Molano-Franco MD MSc , Luis Alexander Peña-López PT MSc , Purificación Pérez- Terán MD Spec , Joan Ramon Masclans MD Spec
{"title":"Diaphragmatic Rapid Shallow Breathing Index for predicting successful weaning from mechanical ventilation: A systematic review and meta-analysis","authors":"Henry Mauricio Parada-Gereda PT MSc , Daniel Molano-Franco MD MSc , Luis Alexander Peña-López PT MSc , Purificación Pérez- Terán MD Spec , Joan Ramon Masclans MD Spec","doi":"10.1016/j.aucc.2025.101266","DOIUrl":"10.1016/j.aucc.2025.101266","url":null,"abstract":"<div><h3>Background</h3><div>The Diaphragmatic Rapid Shallow Breathing Index (D-RSBI) has been proposed as a promising tool for predicting successful weaning from mechanical ventilation. By focussing on diaphragmatic activity, the D-RSBI aims to overcome the limitations of the classic rapid shallow breathing index, providing a more specific assessment of the patient's ability to sustain independent breathing following extubation.</div></div><div><h3>Methods</h3><div>Two investigators conducted independent systematic searches in the PubMed, Embase, Cochrane Database, Scopus, Medline, Science Direct, and Epistemonikos databases, covering publications from inception to 30 November 2024. Study quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. A meta-analysis was performed using the random-effect model, calculating sensitivity, specificity, diagnostic odds ratio, and the area under the summary receiver operating characteristic curve for the D-RSBI. The systematic review protocol was registered in the Centre for Reviews and Dissemination database 42024582489 of the Prospective International Registry of Systematic Reviews. Subgroup analyses, bivariate meta-regressions, and sensitivity analyses were conducted. Publication bias was evaluated using a funnel plot, along with Begg's and Egger's tests. The certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation methodology.</div></div><div><h3>Results</h3><div>Fourteen studies were included in the meta-analysis, comprising a total of 1104 patients. The D-RSBI score was significantly lower in the successful weaning group than in the failure group, with a mean difference of −1.09 (95% confidence interval: -1.36 to −0.82; p < 0.05). The pooled sensitivity was 0.88, specificity was 0.82, and the area under the curve was 0.93. The diagnostic odds ratio was 45.2 (95% confidence interval: 23.5 to 87.2; p < 0.05). The studies included were of moderate to high quality, and the certainty of the evidence was rated as moderate.</div></div><div><h3>Conclusions</h3><div>The D-RSBI appears to be a promising predictor for forecasting the success of weaning from mechanical ventilation, offering adequate sensitivity and specificity. However, further clinical trials are needed to confirm and validate these findings and thus to establish the score's potential for enhancing the clinical management of weaning in critically ill patients.</div></div>","PeriodicalId":51239,"journal":{"name":"Australian Critical Care","volume":"38 5","pages":"Article 101266"},"PeriodicalIF":2.6,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144272354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luke A. Perry MBBS(Hons) , Greta G. Brooks BA , Noah Greifer PhD , Jackson Hua MD , Belinda Phillips B.Med, FANZCA , Andrew Silvers MBBS, FANZCA , Bobby Ou Yang MD , Zac Tsigaras MD , Bernard Borann BSc(Hons) , Victor Hui MBBS, FANZCA , Rinaldo Bellomo MD, PhD, FCICM
{"title":"The influence of sex on early postoperative opioid administration after cardiac surgery","authors":"Luke A. Perry MBBS(Hons) , Greta G. Brooks BA , Noah Greifer PhD , Jackson Hua MD , Belinda Phillips B.Med, FANZCA , Andrew Silvers MBBS, FANZCA , Bobby Ou Yang MD , Zac Tsigaras MD , Bernard Borann BSc(Hons) , Victor Hui MBBS, FANZCA , Rinaldo Bellomo MD, PhD, FCICM","doi":"10.1016/j.aucc.2025.101260","DOIUrl":"10.1016/j.aucc.2025.101260","url":null,"abstract":"<div><h3>Background</h3><div>Female patients are at an increased risk of experiencing severe postoperative pain and developing chronic pain after cardiac surgery. However, the impact of sex on postoperative opioid administration is underexplored.</div></div><div><h3>Methods</h3><div>This single-centre retrospective cohort study included adults undergoing coronary artery bypass grafting, valve surgery, or a combined procedure at a quaternary referral hospital, between November 2012 and June 2021. Patients were classified as female or male based on biological sex. Opioid doses were converted to oral morphine equivalent daily doses (oMEDDs) to enable comparisons. Energy balancing was used to adjust for baseline differences, including body weight and other confounders. Sex differences in gabapentinoid and antipsychotic drug administration were also evaluated. The aim of this study was to evaluate the association of patient sex and perioperative opioid administration after cardiac surgery.</div></div><div><h3>Results</h3><div>We studied 3188 patients: 825 (25.9%) females and 2363 (74.1%) males. After adjusting for body weight and other confounders, female patients received significantly less opioid analgesia on postoperative day 1 (oMEDD difference: −5.70 mg [95% confidence interval {CI}: −3.15 to −8.25], p < 0.0001), day 2 (oMEDD difference: −9.06 mg [95% CI: −5.05 to −13.08], p < 0.0001), and day 3 (oMEDD difference: −4.50 mg [95% CI: −0.52 to −8.47], p < 0.03). Female patients were also more likely to be prescribed a gabapentinoid (odds ratio: 1.47 [95% CI: 1.02 to 2.13], p = 0.04) but less likely to be prescribed an antipsychotic (odds ratio: 0.63 [95% CI: 0.46–0.86], p = 0.004).</div></div><div><h3>Conclusion</h3><div>In a single-centre cohort study involving over 3000 cardiac surgery patients, female sex was associated with the administration of significantly lower doses of postoperative opioid. Providers involved in the care of cardiac surgery patients should be aware of the potential for implicit bias, and further studies are required to identify mechanisms for the observed disparities.</div></div>","PeriodicalId":51239,"journal":{"name":"Australian Critical Care","volume":"38 5","pages":"Article 101260"},"PeriodicalIF":2.6,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond hype: Separating large language model–driven health literacy from clinical decision support system diagnostic rigour","authors":"Zekai Yu BSc Candidate","doi":"10.1016/j.aucc.2025.101265","DOIUrl":"10.1016/j.aucc.2025.101265","url":null,"abstract":"","PeriodicalId":51239,"journal":{"name":"Australian Critical Care","volume":"38 5","pages":"Article 101265"},"PeriodicalIF":2.6,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144262769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melissa J. Bloomer RN, PhD, FACCCN, Laura A. Brooks RN, PhD, MACCCN, Krishnaswamy Sundararajan MD, FCICM, Elizabeth Manias RN, PhD, FACCCN
{"title":"Perpetuating collective constructs and othering: We need to do better with identifying and reporting cultural characteristics in critical care research","authors":"Melissa J. Bloomer RN, PhD, FACCCN, Laura A. Brooks RN, PhD, MACCCN, Krishnaswamy Sundararajan MD, FCICM, Elizabeth Manias RN, PhD, FACCCN","doi":"10.1016/j.aucc.2025.101282","DOIUrl":"10.1016/j.aucc.2025.101282","url":null,"abstract":"","PeriodicalId":51239,"journal":{"name":"Australian Critical Care","volume":"38 4","pages":"Article 101282"},"PeriodicalIF":2.6,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144231162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-traumatic stress disorder specific to parents in the neonatal intensive care unit","authors":"Lisa McKeown BN , Sonia Pervin PhD , Kylie Burke PhD , Vanessa E. Cobham PhD , Katie Foxcroft BN, MAppSc , Leonie Callaway MBBS (Hons I), FRACP, PhD","doi":"10.1016/j.aucc.2025.101257","DOIUrl":"10.1016/j.aucc.2025.101257","url":null,"abstract":"<div><h3>Introduction</h3><div>The experience of having an infant admitted to the neonatal intensive care unit (NICU) can be highly traumatic for parents, potentially leading to symptoms of post-traumatic stress disorder (PTSD). Despite the significant emotional impact of the NICU experience, the prevalence rates of probable PTSD among NICU parents, as measured by validated Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, (DSM-5) self-report instruments, have not been extensively documented. The aim of this study was to address this gap.</div></div><div><h3>Objective</h3><div>The aim of this pilot study was to assess the prevalence rates of probable PTSD in NICU parents at five time points over 12 months. A secondary aim was to identify differences in probable PTSD between mothers and fathers.</div></div><div><h3>Methods</h3><div>The standardised PTSD Checklist for DSM-5 self-report measure was used to screen parents for symptoms of probable PTSD at the NICU hospital admission, discharge, and 3 months, 6 months, and 12 months of infant corrected age. Probable PTSD was identified with a cut-off score ≥31.</div></div><div><h3>Results</h3><div>A total of 102 parents participated in the study. At hospital admission, 13% of NICU parents met the criteria for a probable PTSD diagnosis, with mothers being twice as likely as fathers to report PTSD symptoms. The majority of parents recovered. A critical subset of parents (6%) reported severe and persistent symptoms of probable PTSD at 12 months.</div></div><div><h3>Conclusions</h3><div>The use of the PTSD Checklist for DSM-5 administered by neonatal nurses can help identify potential signs of parental stress or trauma. Further research must assess whether early screening and referral improve parental outcomes.</div></div>","PeriodicalId":51239,"journal":{"name":"Australian Critical Care","volume":"38 4","pages":"Article 101257"},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144137756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meilin Liu BS, RN , Ya Guo BS, RN , Jing Bai BS, RN, Zhuoling Wang BM, Jiming Han PhD, MD, Jiayu Zhu BS, RN, Jin Wang MSN, RN
{"title":"Effectiveness of mindfulness-based interventions on psychosocial well-being and occupational-related outcomes among nurses in the intensive care unit: A systematic review and meta-analysis","authors":"Meilin Liu BS, RN , Ya Guo BS, RN , Jing Bai BS, RN, Zhuoling Wang BM, Jiming Han PhD, MD, Jiayu Zhu BS, RN, Jin Wang MSN, RN","doi":"10.1016/j.aucc.2025.101255","DOIUrl":"10.1016/j.aucc.2025.101255","url":null,"abstract":"<div><h3>Background</h3><div>Mindfulness-based interventions may contribute to the mental health status and well-being of nurses. Current results are inconsistent, and there are no systematic review and meta-analyses for intensive care unit (ICU) nurses.</div></div><div><h3>Aim</h3><div>The aim of this study was to assess the effectiveness of mindfulness-based interventions on psychosocial well-being and occupational-related outcomes among nurses in the ICU.</div></div><div><h3>Methods</h3><div>We conducted a comprehensive literature search across 12 electronic databases, including PubMed, Web of Science, Embase, CINAHL, PsycINFO, Cochrane Library, CNKI, Wanfang, VIP, SinoMed, ClinicalTrials.gov, and preprint repositories (bioRxiv and medRxiv). Additionally, we screened the reference lists of included studies to identify other potentially relevant research. The search covered records from the inception of each database up to July 2024. Two researchers independently screened studies and extracted data. ReviewManager (version 5.3 was used to conduct the meta-analysis.</div></div><div><h3>Results</h3><div>A total of 29 studies were included in the meta-analysis to evaluate the effects of mindfulness-based interventions across different timeframes: immediate-term effects (within 10 days post intervention), short-term effects (10 days–3 months), medium-term effects (3–6 months), and long-term effects (beyond 6 months). The results showed that mindfulness-based interventions significantly alleviated anxiety (mean difference [MD]: −10.80, 95% confidence interval [CI]: [-16.76, −4.83], I<sup>2</sup> = 78%, <em>P</em> < 0.001) and depression (MD: −12.02, 95% CI: [-12.43, −11.61], I<sup>2</sup> = 0%, <em>P</em> < 0.001) in the medium term for ICU nurses. Significant immediate-term effects were observed on well-being (standardised mean difference [SMD]: 0.58, 95% CI: [0.40, 0.76], I<sup>2</sup> = 0%, <em>P</em> < 0.001), resilience (MD: 14.41, 95% CI: [9.71, 19.11], I<sup>2</sup> = 91%, <em>P</em> < 0.001), and death anxiety (MD: −2.35, 95% CI: [-4.39, −0.31], I<sup>2</sup> = 30%, <em>P</em> = 0.02). Mindfulness-based interventions also showed significant short-term effects on well-being (SMD: 0.54, 95% CI: [0.10, 0.99], I<sup>2</sup> = 43%, <em>P</em> = 0.02), sleep quality (MD: −1.19, 95% CI: [-2.32, −0.05], I<sup>2</sup> = 50%, <em>P</em> = 0.04), and stress (SMD: −0.75, 95% CI: [-1.34, −0.17], I<sup>2</sup> = 79%, <em>P</em> = 0.01). Significant effects were observed across immediate-term, short-term, and medium-term timeframes for stress reduction (medium-term effects: MD: −9.69, 95% CI: [-10.18, −9.21], I<sup>2</sup> = 0%, <em>P</em> < 0.001) and mindfulness improvement (medium-term effects: MD: 9.28, 95% CI: [7.20, 11.37], I<sup>2</sup> = 0%, <em>P</em> < 0.001). Additionally, mindfulness-based interventions significantly reduced burnout in the immediate term (SMD: −1.28, 95% CI: [-2.31, −0.25], I<sup>2</sup> = 92%, <em>P</em> = 0.0","PeriodicalId":51239,"journal":{"name":"Australian Critical Care","volume":"38 4","pages":"Article 101255"},"PeriodicalIF":2.6,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144134432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sameer A. Alkubati RN, PhD , Essa Alshammari RN, MSN , Hamdan Albaqawi RN, PhD , Abdulhafith Alharbi RN, PhD , Adel O. Laradhi RN, PhD , Galal F. Albani RN, PhD , Eddieson Pasay-an RN, PhD , Mohamed A. Tlili RN, PhD , Aziza Z. Ali RN, PhD
{"title":"The mediating effect of resilience on the relationship between alarm fatigue and burnout among critical care nurses","authors":"Sameer A. Alkubati RN, PhD , Essa Alshammari RN, MSN , Hamdan Albaqawi RN, PhD , Abdulhafith Alharbi RN, PhD , Adel O. Laradhi RN, PhD , Galal F. Albani RN, PhD , Eddieson Pasay-an RN, PhD , Mohamed A. Tlili RN, PhD , Aziza Z. Ali RN, PhD","doi":"10.1016/j.aucc.2025.101258","DOIUrl":"10.1016/j.aucc.2025.101258","url":null,"abstract":"<div><h3>Background</h3><div>Burnout is a common problem in intensive care units and may be related to exposure to high levels of alarms.</div></div><div><h3>Objectives</h3><div>The aims of this study were to identify factors influencing burnout among critical care nurses and to examine the role of resilience in mediating the relationship between alarm fatigue and burnout.</div></div><div><h3>Methods</h3><div>A cross-sectional correlational design was used with 306 critical care nurses in critical and intensive care units in Ha'il City, Saudi Arabia's public hospitals from June to August 2024. A path analysis was conducted using the AMOS 23.0 software.</div></div><div><h3>Results</h3><div>Multiple linear regression analysis revealed that being Saudi (p = 0.033), having more years of experience (p = 0.020), and having a higher alarm fatigue score or lower resilience were significant predictors of higher emotional exhaustion. Having more years of experience (p < 0.001), higher alarm fatigue scores (p = 0.001), and lower resilience (p < 0.001) were significant predictors of higher depersonalisation. Alarm fatigue had an indirect impact on emotional exhaustion and depersonalisation (β = 0.12, p < 0.001 and β = 0.09, p < 0.001, respectively). Furthermore, alarm fatigue had a significant positive direct effect on emotional exhaustion and depersonalisation (β = 0.31, p < 0.001 and β = 0.19, p = 0.011, respectively) and a negative direct effect on resilience and personal achievement (β = −0.32, p < 0.001 and β = −0.25, p < 0.001, respectively). In addition, alarm fatigue had a total positive effect on emotional exhaustion and depersonalisation (β = 0.43, p < 0.001 and β = 0.28, p = 0.001, respectively) and a negative effect on personal achievement (β = −0.28, p < 0.001). Resilience had a direct negative effect on emotional exhaustion and depersonalisation (β = −0.37, p < 0.001 and β = −0.28, p < 0.001, respectively).</div></div><div><h3>Conclusion</h3><div>The findings revealed a high prevalence of emotional exhaustion and depersonalisation coupled with low levels of personal accomplishment. Resilience partially mediates the relationship between alarm fatigue, emotional exhaustion, and depersonalisation. Healthcare institutions must initiate proper alarm systems and training programs to help mitigate unnecessary alarms and empower resilience among nurses.</div></div>","PeriodicalId":51239,"journal":{"name":"Australian Critical Care","volume":"38 4","pages":"Article 101258"},"PeriodicalIF":2.6,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Critical care nurses’ responses to clinical scenarios involving cardiopulmonary resuscitation for deceased inpatients without a Do Not Resuscitate order: A cross-sectional study","authors":"Heidi Hoi Ying Hui RN, MPH , Joanne Cordina RN, GradCertNurs , Judeil Krlan Teus RN, MAdvN , Susan Maitland RN, MN , Michael Watts RN, GCertCritCare , Sahn Zanotti RN, GradCertNurs , Suzanne Sheppard-Law RN, PhD , Eamon Merrick RN, PhD , George Skowronski MBBS(HONS), FRACP, FRCP, FCICM , Suzanne Bowdler RN, MN , Edwina Light PhD , Amy Montgomery RN, NP, PhD , Anne Preisz MBioeth , Linda Sheahan MBE, FRACP, FAChPM , Cameron Stewart PhD, FACLM(Hons), FAAL , Ian Kerridge MPhil, FRACP, FRCPA , Gemma McErlean RN, PhD","doi":"10.1016/j.aucc.2025.101254","DOIUrl":"10.1016/j.aucc.2025.101254","url":null,"abstract":"<div><h3>Background</h3><div>Current Australian resuscitation training focusses on the practical application of cardiopulmonary resuscitation but lacks clarity on when it is inappropriate. Nurses are often first responders to inpatient emergencies and may take different approaches to cardiopulmonary resuscitation due to their views about its benefit. There is a lack of literature on how the absence of Do Not Resuscitate orders affect nurses’ decisions regarding resuscitation in hospital settings.</div></div><div><h3>Objective</h3><div>The aim of this study was to explore nurse's views of initiating cardiopulmonary resuscitation on inpatients with unequivocal signs of death without a Do Not Resuscitate order, using hypothetical scenarios.</div></div><div><h3>Methods</h3><div>The cross-sectional survey recruited nurses across five Australian hospitals between October 2023 and April 2024. Participants were provided two hypothetical clinical scenarios (scenario 1: Mr D, an 84-year-old man; scenario 2: Mr G, a 35-year-old man). In both scenarios, the patients had unequivocal signs of death and absent Do Not Resuscitate orders. Respondents were asked to indicate their actions. Responses from participants working in the intensive care unit, emergency department, or critical care are reported here. Results were analysed using descriptive statistics.</div></div><div><h3>Results</h3><div>Eighty participants working in the intensive care unit, emergency department, or critical care completed the survey. Most nurses indicated they would call a Code Blue and initiate full resuscitation in both scenarios (scenario 1: 51.3% [n = 41] vs scenario 2: 92.5% [n = 74]). Fear and a misunderstanding of the law was a recurring reason for initiating resuscitation in both scenarios. Ethical judgement and family's expectations were predominant reasons for initiating resuscitation for the younger patient (scenario 2).</div></div><div><h3>Conclusions</h3><div>Most nurses working in the intensive care unit, emergency department, or critical care areas chose to call a Code Blue and initiate full resuscitation in both scenarios where patients showed unequivocal signs of death and an absent Do Not Resuscitate order. Nurses' decisions were influenced by multiple factors, including patient's age and misconception of the law.</div></div>","PeriodicalId":51239,"journal":{"name":"Australian Critical Care","volume":"38 4","pages":"Article 101254"},"PeriodicalIF":2.6,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144114976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}