发布求助
文献互助 智能选刊 最新文献

Veterinary Therapeutics最新文献

筛选
英文 中文
Evaluation of intraoperative culture results as a predictor for short-term incisional complications in 49 horses undergoing abdominal surgery. 评估术中培养结果作为49匹接受腹部手术的马短期切口并发症的预测因子。
Veterinary Therapeutics Pub Date : 2009-01-01
Francisco Rodriguez, Joanne Kramer, William Fales, David Wilson, Kevin Keegan
{"title":"Evaluation of intraoperative culture results as a predictor for short-term incisional complications in 49 horses undergoing abdominal surgery.","authors":"Francisco Rodriguez,&nbsp;Joanne Kramer,&nbsp;William Fales,&nbsp;David Wilson,&nbsp;Kevin Keegan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study evaluated bacterial isolates obtained during abdominal surgery and their relationship to short-term incisional complications. Samples of peritoneal fluid and from resection and/or enterotomy sites from 49 horses were cultured, with 96% having at least one positive culture result. The most common isolates were Escherichia coli, Streptococcus spp, and Enterococcus spp. Horses with small intestinal resections were more likely to grow obligate anaerobes and enteric organisms. Horses with small intestinal lesions (+/- resection) were more likely to grow enteric organisms and less likely to grow non-enteric organisms. Horses without enterotomy or resection procedures were more likely to grow 3 isolates and did not grow obligate anaerobes. The continued incisional drainage rate was 10%. Horses with preoperative peripheral leukocyte counts >8,500 cells/ul were more likely to develop incisional drainage. Many horses undergoing abdominal surgery may have positive intraoperative culture results. Our results did not provide evidence for the routine use of intraoperative culture to predict short-term incisional complications. Further studies are needed to evaluate the value of intraoperative culture in horses at high risk for incisional complications.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"10 4","pages":"E1-13"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28951370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ceftiofur susceptibility of Streptococcus equi subsp zooepidemicus isolated from horses in North America between 1989 and 2008. 1989年至2008年北美马分离的马链球菌亚种动物流行病学对头孢噻福的敏感性
Veterinary Therapeutics Pub Date : 2009-01-01
Donald Bade, Gary Sibert, John Hallberg, Ellen Portis, Joseph Boucher, Lawrence Bryson
{"title":"Ceftiofur susceptibility of Streptococcus equi subsp zooepidemicus isolated from horses in North America between 1989 and 2008.","authors":"Donald Bade,&nbsp;Gary Sibert,&nbsp;John Hallberg,&nbsp;Ellen Portis,&nbsp;Joseph Boucher,&nbsp;Lawrence Bryson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In vitro activity of ceftiofur and six other antimicrobial agents was assessed for 516 Streptococcus equi subsp zooepidemicus isolates collected from horses with lower respiratory tract infections in North America in 2007 and 2008 and 239 equine S. equi subsp zooepidemicus isolates received from US and Canadian veterinary diagnostic laboratories between 1989 and 2007. The lowest concentration of ceftiofur inhibiting the growth of 90% of the isolates (MIC90) was 0.12 microg/ml for both groups of isolates. The Clinical and Laboratory Standards Institute susceptible breakpoint set for ceftiofur against this organism is a minimal inhibitory concentration value of ≤ 0.25 microg/ml. The MIC90 values remained consistent for isolates collected over 19 years.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"10 4","pages":"E1-7"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28951978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves. 在长时间、高度应激的牛肉饲养小牛中，预防使用图拉霉素和替米考星对短期健康和生产性能的影响的比较。
Veterinary Therapeutics Pub Date : 2008-09-25 DOI: 10.21423/aabppro20084407
J. Nickell, B. White, R. Larson, D. Blasi, D. Renter
{"title":"Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves.","authors":"J. Nickell, B. White, R. Larson, D. Blasi, D. Renter","doi":"10.21423/aabppro20084407","DOIUrl":"https://doi.org/10.21423/aabppro20084407","url":null,"abstract":"Health and feed performance parameters of 293 beef stocker calves at risk for bovine respiratory disease were compared after metaphylactic administration of one of two antimicrobials (tulathromycin or tilmicosin) with different durations of activity; the antimicrobial was administered 1 day after arrival. Calves that received metaphylactic tulathromycin displayed significant improvement in morbidity, mortality, and first-treatment success rates (P<.05) compared with tilmicosin-treated calves. Tulathromycin-treated calves also showed a significantly improved average daily gain and feed:gain ratio (P<.05) compared with tilmicosin-treated calves. Under conditions of this study, calves receiving tulathromycin were healthier through a 43-day growing phase compared with calves receiving tilmicosin. This health difference likely accounted for the differences in feed performance between the treatment groups.","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"9 2 1","pages":"147-56"},"PeriodicalIF":0.0,"publicationDate":"2008-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68574618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Clinical efficacy of a single injection of ceftiofur crystalline free acid sterile injectable suspension versus three daily injections of ceftiofur sodium sterile powder for the treatment of footrot in feedlot cattle. 单次注射头孢替弗结晶游离酸无菌注射混悬液与每日三次注射头孢替弗钠无菌粉剂治疗饲养场牛足疾的临床疗效。
Veterinary Therapeutics Pub Date : 2008-01-01
Joyce Van Donkersgoed, Marike Dussault, Pete Knight, Les Byers
{"title":"Clinical efficacy of a single injection of ceftiofur crystalline free acid sterile injectable suspension versus three daily injections of ceftiofur sodium sterile powder for the treatment of footrot in feedlot cattle.","authors":"Joyce Van Donkersgoed,&nbsp;Marike Dussault,&nbsp;Pete Knight,&nbsp;Les Byers","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study was conducted in a feedlot in Alberta, Canada, to compare the clinical efficacy of a single injection of ceftiofur crystalline free acid sterile injectable suspension with three daily treatments of ceftiofur sodium sterile powder for the treatment of footrot. Use of a long-acting antimicrobial to treat footrot would reduce labor costs and hospital pen space requirements during high-risk periods. Four hundred cattle clinically diagnosed with footrot were systematically randomized to one of two treatment groups. The treatment success rate at 14 days after treatment (99.5% for ceftiofur crystalline free acid sterile injectable suspension and 99.0% for ceftiofur sodium sterile powder for injection) was not statistically different (P>.05) between the two drugs.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"9 2","pages":"157-62"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37426218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative evaluation of the speed of kill and duration of efficacy against weekly infestations with fleas on cats treated with fipronil-(S)-methoprene or metaflumizone. 用氟虫腈-(S)-甲氧丁烯或metaflumizone治疗猫的每周跳蚤感染的杀灭速度和有效持续时间的比较评价。
Veterinary Therapeutics Pub Date : 2008-01-01
M Franc, F Beugnet
{"title":"A comparative evaluation of the speed of kill and duration of efficacy against weekly infestations with fleas on cats treated with fipronil-(S)-methoprene or metaflumizone.","authors":"M Franc,&nbsp;F Beugnet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Spot-on formulations of metaflumizone and a combination of fipronil-(S)-methoprene were evaluated in adult cats to determine the duration of 24- and 48-hour efficacy and short-term speed of kill against adult cat fleas, Ctenocephalides felis felis. Speed of kill efficacies (at 12, 18, 24, and 48 hours) were assessed against existing (day -1) infestations and against infestations at day 7, and efficacy was assessed 24 and 48 hours after weekly flea infestations through day 42. Cats treated with fipronil-(S)-methoprene had significantly (P<.01) fewer fleas than those treated with metaflumizone at 12 and 18 hours after treatment (day 0) and on the day 7 infestations. Fipronil-(S)-methoprene-treated cats also had significantly (P<.05) fewer fleas than metaflumizone-treated cats for all 24-hour counts from initial treatment on day 0 through infestation day 42 and for the 48-hour counts on day 28 through day 42.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"9 2","pages":"102-10"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37426268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacokinetics of buccal mucosal administration of fentanyl in a carboxymethylcellulose gel compared with IV administration in dogs. 羧甲基纤维素凝胶芬太尼口腔黏膜给药与静脉给药的药代动力学比较。
Veterinary Therapeutics Pub Date : 2008-01-01
Amy A Little, Ursula Krotscheck, Dawn M Boothe, Hollis N Erb
{"title":"Pharmacokinetics of buccal mucosal administration of fentanyl in a carboxymethylcellulose gel compared with IV administration in dogs.","authors":"Amy A Little,&nbsp;Ursula Krotscheck,&nbsp;Dawn M Boothe,&nbsp;Hollis N Erb","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The pharmacokinetics of fentanyl administrated IV (0.01 mg/kg) and in a carboxymethylcellulose gel (0.05 mg/kg) applied to the buccal mucosa of six healthy adult medium- to large-breed dogs was evaluated. At 5 minutes after transmucosal (TM) administration, serum fentanyl levels above the therapeutic target (0.95 ng/ml) were achieved in all dogs. Except for the longer duration of serum fentanyl concentrations above the therapeutic target associated with TM administration, no significant pharmacokinetic differences were found between IV and TM fentanyl. TM fentanyl may be considered a noninvasive alternative to IV administration with rapid achievement of serum fentanyl concentrations.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"9 3","pages":"201-11"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27834305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of S-adenosylmethionine tablets on the reduction of age-related mental decline in dogs: a double-blinded, placebo-controlled trial. s -腺苷蛋氨酸片对减少犬年龄相关智力衰退的影响:一项双盲、安慰剂对照试验。
Veterinary Therapeutics Pub Date : 2008-01-01
C A Rème, V Dramard, L Kern, J Hofmans, C Halsberghe, D Vida Mombiela
{"title":"Effect of S-adenosylmethionine tablets on the reduction of age-related mental decline in dogs: a double-blinded, placebo-controlled trial.","authors":"C A Rème,&nbsp;V Dramard,&nbsp;L Kern,&nbsp;J Hofmans,&nbsp;C Halsberghe,&nbsp;D Vida Mombiela","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Oral S-adenosylmethionine (SAMe) tosylate supplementation (Novifit tablets, Virbac) was evaluated as a dietary aid for the management of age-related mental impairment in dogs. Thirty-six dogs older than 8 years that had displayed signs of cognitive dysfunction for at least 1 month were selected for the study. The dogs were administered 18 mg/kg SAMe tosylate (n=17) or identical placebo tablets (n=19) for 2 months. Concurrent behavioral treatment was forbidden. A 14-item standardized questionnaire evaluated behavior and locomotion difficulties. Compared with the placebo group, SAMe-treated dogs showed greater improvement in activity (41.7% versus 2.6% after 4 weeks, P<.0003; 57.1% versus 9.0% after 8 weeks, P<.003) and awareness (33.3% versus 17.9% after 4 weeks, P<.05; 59.5% versus 21.4% after 8 weeks, P<.01). The aggregate mental impairment score was reduced by more than 50% in 41.2% and 15.8% of dogs treated with SAMe and placebo, respectively, at week 8. SAMe tosylate tablets proved safe and effective in improving signs of age-related mental decline in dogs.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"9 2","pages":"69-82"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37425967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacokinetics of buprenorphine following intravenous and oral transmucosal administration in dogs. 丁丙诺啡经黏膜静脉和口服给药后的药代动力学。
Veterinary Therapeutics Pub Date : 2008-01-01
Lisa A Abbo, Jeff C H Ko, Lara K Maxwell, Raymond E Galinsky, David E Moody, Brenda M Johnson, Wenfang B Fang
{"title":"Pharmacokinetics of buprenorphine following intravenous and oral transmucosal administration in dogs.","authors":"Lisa A Abbo,&nbsp;Jeff C H Ko,&nbsp;Lara K Maxwell,&nbsp;Raymond E Galinsky,&nbsp;David E Moody,&nbsp;Brenda M Johnson,&nbsp;Wenfang B Fang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pharmacokinetic analysis of buprenorphine administered to six healthy dogs via the oral transmucosal (OTM) route at doses of 20 and 120 microg/kg was conducted using liquid chromatography-electrospray ionization-tandem mass spectroscopy (LC-ESI-MS/MS). Bioavailability was 38% plus or minus 12% for the 20 microg/kg dose and 47%+/-16% for the 120 microg/kg dose. Maximum plasma concentrations were similar for buprenorphine doses of 20 microg/kg IV and 120 microg/kg OTM. Sedation and salivation were common side effects, but no bradycardia, apnea, or cardiorespiratory depressive effects were seen. When the two OTM dosing rates were normalized to dose, LC-ESI-MS/MS analysis of buprenorphine and its metabolites detected no significant difference (P>.05), indicating dose proportionality. The results of this study suggest that OTM buprenorphine may be an alternative for pain management in dogs.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"9 2","pages":"83-93"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37426266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves. 在长时间、高度应激的牛肉饲养小牛中，预防使用图拉霉素和替米考星对短期健康和生产性能的影响的比较。
Veterinary Therapeutics Pub Date : 2008-01-01
J S Nickell, B J White, R L Larson, D A Blasi, D G Renter
{"title":"Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves.","authors":"J S Nickell,&nbsp;B J White,&nbsp;R L Larson,&nbsp;D A Blasi,&nbsp;D G Renter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Health and feed performance parameters of 293 beef stocker calves at risk for bovine respiratory disease were compared after metaphylactic administration of one of two antimicrobials (tulathromycin or tilmicosin) with different durations of activity; the antimicrobial was administered 1 day after arrival. Calves that received metaphylactic tulathromycin displayed significant improvement in morbidity, mortality, and first-treatment success rates (P<.05) compared with tilmicosin-treated calves. Tulathromycin-treated calves also showed a significantly improved average daily gain and feed:gain ratio (P<.05) compared with tilmicosin-treated calves. Under conditions of this study, calves receiving tulathromycin were healthier through a 43-day growing phase compared with calves receiving tilmicosin. This health difference likely accounted for the differences in feed performance between the treatment groups.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"9 2","pages":"147-56"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37426273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demonstration of 1-year duration of immunity for attenuated Bordetella bronchiseptica vaccines in dogs. 证明犬对减毒支气管脓毒杆菌疫苗的免疫持续时间为1年。
Veterinary Therapeutics Pub Date : 2008-01-01
Craig Lehar, Huchappa Jayappa, Jason Erskine, Alicia Brown, Diane Sweeney, Terri Wassmoen
{"title":"Demonstration of 1-year duration of immunity for attenuated Bordetella bronchiseptica vaccines in dogs.","authors":"Craig Lehar,&nbsp;Huchappa Jayappa,&nbsp;Jason Erskine,&nbsp;Alicia Brown,&nbsp;Diane Sweeney,&nbsp;Terri Wassmoen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Three groups of healthy dogs with low antibody titers to Bordetella bronchiseptica (Bb), canine parainfluenza virus (CPI), and canine adenovirus type 2 (CAV-2) were used in this study. One group was vaccinated with a single dose of monovalent attenuated Bb vaccine and one group with a trivalent vaccine containing attenuated Bb, CPI, and CAV-2; dogs were vaccinated intranasally with a single dose of the respective vaccines. The third group served as unvaccinated controls. All vaccinated dogs subsequently developed serum antibody titers to Bb that persisted for at least 1 year. Following Bb challenge 1 year after vaccination, all vaccinated dogs, regardless of group, showed significantly fewer clinical signs and shed significantly fewer challenge organisms than unvaccinated controls. These results demonstrate that intranasal administration of a single dose of monovalent attenuated Bb vaccine or trivalent vaccine containing attenuated Bb, CPI, and CAV-2 provides 1 year of protection against Bb.</p>","PeriodicalId":51211,"journal":{"name":"Veterinary Therapeutics","volume":"9 4","pages":"257-62"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27951483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信