Hearts最新文献 - Book学术

Breaking Boundaries: From Fall to Rapid Cardiac Rescue 打破界限：从跌倒到快速心脏复苏

Hearts Pub Date : 2024-07-22 DOI: 10.3390/hearts5030021

M. D’Alonzo, Mariantonietta Piscitelli, Francesco Cilia

引用次数: 0

Supervised Machine Learning to Examine Factors Associated with Respiratory Sinus Arrhythmias and Ectopic Heart Beats in Adults: A Pilot Study 通过有监督的机器学习研究成人呼吸性窦性心律失常和异位心搏的相关因素：试点研究

Hearts Pub Date : 2024-07-05 DOI: 10.3390/hearts5030020

Peyton Lahr, Chloe Carling, Joseph Nauer, Ryan McGrath, James W. Grier

{"title":"Supervised Machine Learning to Examine Factors Associated with Respiratory Sinus Arrhythmias and Ectopic Heart Beats in Adults: A Pilot Study","authors":"Peyton Lahr, Chloe Carling, Joseph Nauer, Ryan McGrath, James W. Grier","doi":"10.3390/hearts5030020","DOIUrl":"https://doi.org/10.3390/hearts5030020","url":null,"abstract":"Background: There are many types of arrhythmias which may threaten health that are well-known or opaque. The purpose of this pilot study was to examine how different cardiac health risk factors rank together in association with arrhythmias in young, middle-aged, and older adults. Methods: The analytic sample included 101 adults aged 50.6 ± 22.6 years. Several prominent heart-health-related risk factors were self-reported. Mean arterial pressure and body mass index were collected using standard procedures. Hydraulic handgrip dynamometry measured strength capacity. A 6 min single-lead electrocardiogram evaluated arrhythmias. Respiratory sinus arrhythmias (RSAs) and ectopic heart beats were observed and specified for analyses. Classification and Regression Tree analyses were employed. Results: A mean arterial pressure ≥ 104 mmHg was the first level predictor for ectopic beats, while age ≥ 41 years was the first level predictor for RSAs. Age, heart rate, stress and anxiety, and physical activity emerged as important variables for ectopic beats (p < 0.05), whereas age, sodium, heart rate, and gender were important for RSAs (p < 0.05). Conclusions: RSAs and ectopic arrhythmias may have unique modifiable and non-modifiable factors that may help in understanding their etiology for prevention and treatment as appropriate across the lifespan.","PeriodicalId":512081,"journal":{"name":"Hearts","volume":" 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141673796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Arterial Stiffness Is an Important Predictor of Heart Failure with Preserved Ejection Fraction (HFpEF)—The Effects of Phosphate Retention 动脉僵化是射血分数保留型心力衰竭 (HFpEF) 的重要预测指标--磷酸盐潴留的影响

Hearts Pub Date : 2024-05-17 DOI: 10.3390/hearts5020014

Yuji Mizuno, Toshifumi Ishida, Kenichi Tsujita, Michihiro Yoshimura

{"title":"Arterial Stiffness Is an Important Predictor of Heart Failure with Preserved Ejection Fraction (HFpEF)—The Effects of Phosphate Retention","authors":"Yuji Mizuno, Toshifumi Ishida, Kenichi Tsujita, Michihiro Yoshimura","doi":"10.3390/hearts5020014","DOIUrl":"https://doi.org/10.3390/hearts5020014","url":null,"abstract":"Heart failure with preserved ejection fraction (HFpEF) is a major health concern. There is a growing recognition of the causal interplay between arterial stiffness and HFpEF. We recently reported that phosphate retention is a trigger for arterial stiffness. This study focuses on whether arterial stiffness due to phosphate retention could be a predictor for HFpEF. Methods: The subjects of this study were 158 patients (68 males and 90 females, mean age 74.8 ± 11.2). HFpEF was defined according to the guidelines of the ESC 2019. Pulse wave velocity (PWV) and central systolic blood pressure (CSBP) were used as markers for arterial stiffness and afterload, respectively. We measured serum levels of fibroblast growth factor 23 (FGF23) as a marker of phosphate retention. Results: The serum levels of FGF23 had a significant relationship with PWV. PWV had significant relationships with LV mass index, plasma BNP levels, and relative wall thickness, e’, and E/e’ (p < 0.001, respectively). Multivariate logistic regression analysis revealed that higher PWV values and hypertension were significant predictors for the dependent factor (HFpEF). Arterial stiffness amplified afterload, leading to LV concentric hypertrophy and diastolic dysfunction. This study presents that arterial stiffness is a key predictor of HFpEF, and that phosphate retention is involved in the pathology of HFpEF.","PeriodicalId":512081,"journal":{"name":"Hearts","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary Fatty Acids Predicting Long Term Cardiovascular Mortality in a Cohort of Middle-Aged Men Followed-Up until Extinction 膳食脂肪酸预测中年男性群体心血管疾病的长期死亡率

Hearts Pub Date : 2024-03-23 DOI: 10.3390/hearts5020013

Alessandro Menotti, P. Puddu

{"title":"Dietary Fatty Acids Predicting Long Term Cardiovascular Mortality in a Cohort of Middle-Aged Men Followed-Up until Extinction","authors":"Alessandro Menotti, P. Puddu","doi":"10.3390/hearts5020013","DOIUrl":"https://doi.org/10.3390/hearts5020013","url":null,"abstract":"Objectives: To report the relationships of major dietary fatty acids with major cardiovascular disease mortality groups in a cohort of middle-aged men followed up with until extinction. Material and Methods: In the early 1960s, a cohort of men aged 40 to 59 years was enrolled and examined within the Italian Rural Areas section of the Seven Countries Study including dietary history that allowed for the estimation of major fatty acid (FA) intake (saturated FAs: SAFAs; mono-unsaturated FAs: MUFAs; and poly-unsaturated FAs: PUFAs), their ratios, and the production of a dietary score derived from 18 food groups, the high levels of which corresponded to a Mediterranean diet profile. Results: During a follow-up of 61 years, the intake of SAFAs was directly while that of MUFAs was inversely and significantly associated with coronary heart disease (CHD) mortality (the hazard ratio for one standard deviation was 1.28 and 0.84, respectively) but not with other cases of Heart Disease of Uncertain Etiology (HDUE) and stroke mortality. The hazard ratio for SAFAs remained significant after factoring into the multivariate models the dietary score and other classical cardiovascular risk factors (age, smoking habits, cholesterol levels, and systolic blood pressure). The role of the dietary score was inverse and significant (hazard ratio of 0.73). Again, this was true for CHD but not for HDUE and stroke mortality. Conclusions: Both SAFAs and MUFAs predict long-term CHD mortality, together with a dietary score, but not HDUE and stroke, which represent different diseases also in relation to dietary habits.","PeriodicalId":512081,"journal":{"name":"Hearts","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140386575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Significance of Smoking in Patients with Acute ST Elevation Myocardial Infarction (STEMI) Undergoing Primary Percutaneous Coronary Intervention: Evaluation of Coronary Flow, Microcirculation and Left Ventricular Systolic Function 接受经皮冠状动脉介入治疗的急性 STEV 心肌梗死 (STEMI) 患者吸烟的意义：评估冠状动脉血流、微循环和左心室收缩功能

Hearts Pub Date : 2024-03-21 DOI: 10.3390/hearts5010012

Mariana Boulos, Yasmine Sharif, Nimer Assy, D. Sharif

{"title":"Significance of Smoking in Patients with Acute ST Elevation Myocardial Infarction (STEMI) Undergoing Primary Percutaneous Coronary Intervention: Evaluation of Coronary Flow, Microcirculation and Left Ventricular Systolic Function","authors":"Mariana Boulos, Yasmine Sharif, Nimer Assy, D. Sharif","doi":"10.3390/hearts5010012","DOIUrl":"https://doi.org/10.3390/hearts5010012","url":null,"abstract":"In the thrombolytic care era, myocardial infarction in cigarette smokers was associated with better six-month outcomes compared to non-smokers. Aims: We tested the hypothesis that in patients with anterior myocardial infarction with ST-segment elevation (STEMI) treated with primary percutaneous coronary intervention (PPCI), cigarette smoking is associated with better coronary artery flow, myocardial perfusion, and left ventricular systolic function. Methods: Ninety-nine patients (sixty-six smokers) with anterior STEMI treated with PPCI were studied. Angiographic coronary artery flow TIMI grades, myocardial blush grades (MBGs) before and after PPCI, ST-segment elevation resolution, maximal troponin I and creatine phosphokinase blood levels, left ventricular echocardiographic systolic function as well as left anterior descending coronary artery (LAD) velocity parameters at admission and at discharge were evaluated. Results: Smokers and non-smokers were treated similarly. In smokers, the age was significantly younger, 54 ± 10, compared to non-smokers, 71.8 ± 10 years, p < 0.05, and had a lower prevalence of women, 13.6% compared to 36.6%. TIMI and MBG before and after PPCI were similar between smokers and non-smokers. Smokers had a lower prevalence of complete ST elevation resolution, 33% compared to 50% in non-smokers. Diastolic LAD velocity and integral were lower in smokers, p < 0.05. Maximal biomarker blood levels as well as LV systolic function at admission and on discharge were similar. Conclusions: Cigarette smokers with anterior STEMI treated with PPCI were younger with a lower prevalence of women and of complete ST elevation resolution and had lower LAD diastolic velocity and integral late after PPCI. However, angiographic parameters and LV systolic function parameters were similar.","PeriodicalId":512081,"journal":{"name":"Hearts","volume":" 59","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140221093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporal Responses of a Low-Energy Meal Replacement Plan or Exercise Training on Cardiovascular Function and Fibro-Inflammatory Markers in People with Type 2 Diabetes—A Secondary Analysis of the “Diabetes Interventional Assessment of Slimming or Training to Lessen Inconspicuous Cardiovascular Dysfun 低能量代餐计划或运动训练对 2 型糖尿病患者心血管功能和纤维炎症标志物的时间反应--"减轻明显心血管疾病的瘦身或训练的糖尿病干预评估 "二次分析

Hearts Pub Date : 2024-03-16 DOI: 10.3390/hearts5010011

J. Bilak, G. Gulsin, V. Bountziouka, K. Parke, Emma L Redman, J. Henson, Lei Zhao, Phillipe Costet, M. Cvijic, Juan Maya, Ching-Pin Chang, Melanie J. Davies, Thomas Yates, G. P. McCann, E. Brady

{"title":"Temporal Responses of a Low-Energy Meal Replacement Plan or Exercise Training on Cardiovascular Function and Fibro-Inflammatory Markers in People with Type 2 Diabetes—A Secondary Analysis of the “Diabetes Interventional Assessment of Slimming or Training to Lessen Inconspicuous Cardiovascular Dysfun","authors":"J. Bilak, G. Gulsin, V. Bountziouka, K. Parke, Emma L Redman, J. Henson, Lei Zhao, Phillipe Costet, M. Cvijic, Juan Maya, Ching-Pin Chang, Melanie J. Davies, Thomas Yates, G. P. McCann, E. Brady","doi":"10.3390/hearts5010011","DOIUrl":"https://doi.org/10.3390/hearts5010011","url":null,"abstract":"Background: This study assesses the temporal responses of cardiovascular function, fibro-inflammation, and glucometabolic profiles in asymptomatic adults with type 2 diabetes, following a low-energy meal replacement plan (MRP) or exercise training. Methods: Secondary analysis of DIASTOLIC: a randomised, open-label, blinded-endpoint trial of 12 weeks MRP (~810 kcal/day) or exercise training. Cardiac magnetic resonance, plasma fibroinflammatory, and metabolic markers were undertaken at baseline, 4, and 12 weeks. Results: Out of 24 participants in the MRP group and 22 in exercise training, 18 and 11 completed all three visits. MRP resulted in early (0–4 weeks) improvement in insulin resistance (HOMA-IR: 10.82 to 4.32), decrease in FABP-4 (4.87 ± 0.19 to 5.15 ± 0.32 mg/L), and improvement in left ventricular remodelling LV mass: volume (0.86± 0.14 to 0.78 ± 0.11), all with large effect sizes. MMP8 levels increased moderately at 4–12 weeks. Peak early diastolic strain rate (cPEDSR) initially decreased, then improved. Exercise training led to minor improvements in insulin resistance and MMP-8 levels, with no significant changes in cPEDSR or LV remodelling. Conclusions: MRP resulted in early improvements in insulin resistance, cardiac remodelling, and inflammation, but with an initial decrease in diastolic function, improving by 12 weeks. Exercise training showed minor early benefits in insulin resistance and inflammation, but no significant cardiac changes.","PeriodicalId":512081,"journal":{"name":"Hearts","volume":"94 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140236621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Second Edition of the German–Austrian S3 Guideline “Infarction-Related Cardiogenic Shock: Diagnosis, Monitoring and Treatment” 德国-奥地利 S3 指导原则 "梗死相关性心源性休克 "第二版：诊断、监测和治疗"

Hearts Pub Date : 2024-03-14 DOI: 10.3390/hearts5010010

Kevin Pilarczyk, Udo Boeken, Martin Russ, Josef Briegel, Michael Buerke, Alexander Geppert, Uwe Janssens, Malte Kelm, Guido Michels, Axel Schlitt, Holger Thiele, Stephan Willems, U. Zeymer, Bernhard Zwissler, Georg Delle-Karth, Markus Wolfgang Ferrari, Hans Reiner Figulla, Axel R. Heller, Gerhard Hindricks, E. Pichler-Cetin, B. Pieske, R. Prondzinsky, Johann Bauersachs, Ina Kopp, K. Werdan, Matthias Thielmann

引用次数: 0

Complications in Acute Myocardial Infarction: Navigating Challenges in Diagnosis and Management 急性心肌梗死并发症：驾驭诊断和管理中的挑战

Hearts Pub Date : 2024-03-13 DOI: 10.3390/hearts5010009

Errol C. Moras, Shreyas Yakkali, K. Gandhi, H. H. Virk, Mahboob Alam, Syed Zaid, Nitin Barman, Hani Jneid, S. Vallabhajosyula, Samin K. Sharma, C. Krittanawong

{"title":"Complications in Acute Myocardial Infarction: Navigating Challenges in Diagnosis and Management","authors":"Errol C. Moras, Shreyas Yakkali, K. Gandhi, H. H. Virk, Mahboob Alam, Syed Zaid, Nitin Barman, Hani Jneid, S. Vallabhajosyula, Samin K. Sharma, C. Krittanawong","doi":"10.3390/hearts5010009","DOIUrl":"https://doi.org/10.3390/hearts5010009","url":null,"abstract":"In recent decades, significant advancements in pharmacological, catheter-based, and surgical reperfusion technologies have markedly improved outcomes for individuals undergoing acute myocardial infarction. Despite these remarkable progressions, a segment of patients, particularly those with extensive infarctions or delays in revascularization, remains vulnerable to the onset of mechanical complications associated with myocardial infarction. These complications, spanning mechanical, electrical, ischemic, inflammatory, and thromboembolic events, pose substantial risks of morbidity, mortality, and increased utilization of hospital resources. The management of patients experiencing these complications is intricate, necessitating collaborative efforts among various specialties. Timely identification, accurate diagnosis, hemodynamic stabilization, and decision-making support are crucial for guiding patients and their families in choosing between definitive treatments or palliative care. This review underscores the critical importance of promptly identifying and initiating therapy to reduce prolonged periods of cardiogenic shock and the potential for fatality. By presenting key clinical and diagnostic insights, this review aims to further improve early diagnosis and offer an updated perspective on current management strategies for the diverse range of complications associated with acute myocardial infarction.","PeriodicalId":512081,"journal":{"name":"Hearts","volume":"394 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140246970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Update on the Use of Artificial Intelligence in Cardiovascular Medicine 人工智能在心血管领域应用的最新进展

Hearts Pub Date : 2024-02-09 DOI: 10.3390/hearts5010007

Shiavax J. Rao, S. Iqbal, A. Isath, H. H. Virk, Zhen Wang, Benjamin S. Glicksberg, C. Krittanawong

引用次数: 0

An Update on the Use of Artificial Intelligence in Cardiovascular Medicine 人工智能在心血管领域应用的最新进展

Hearts Pub Date : 2024-02-09 DOI: 10.3390/hearts5010007

Shiavax J. Rao, S. Iqbal, A. Isath, H. H. Virk, Zhen Wang, Benjamin S. Glicksberg, C. Krittanawong

引用次数: 0