通过有监督的机器学习研究成人呼吸性窦性心律失常和异位心搏的相关因素:试点研究

Hearts Pub Date : 2024-07-05 DOI:10.3390/hearts5030020
Peyton Lahr, Chloe Carling, Joseph Nauer, Ryan McGrath, James W. Grier
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引用次数: 0

摘要

背景:有许多类型的心律失常可能会威胁健康,这些类型的心律失常是众所周知的,也可能是不明确的。本试验性研究的目的是研究不同的心脏健康风险因素在年轻人、中年人和老年人中与心律失常的关系。研究方法分析样本包括 101 名成年人,年龄为 50.6 ± 22.6 岁。几个与心脏健康相关的主要风险因素均为自我报告。采用标准程序收集了平均动脉压和体重指数。液压手握式测力计测量了力量容量。6 分钟单导联心电图对心律失常进行了评估。对呼吸性窦性心律失常(RSA)和异位心搏进行了观察和分析。采用了分类和回归树分析法。结果平均动脉压≥104 mmHg是异位搏动的一级预测因子,而年龄≥41岁是RSA的一级预测因子。年龄、心率、压力和焦虑以及体力活动是异位搏动的重要变量(P < 0.05),而年龄、钠、心率和性别是 RSA 的重要变量(P < 0.05)。结论RSA和异位心律失常可能具有独特的可调节和不可调节因素,这些因素可能有助于了解其病因,从而在整个生命周期内进行适当的预防和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Supervised Machine Learning to Examine Factors Associated with Respiratory Sinus Arrhythmias and Ectopic Heart Beats in Adults: A Pilot Study
Background: There are many types of arrhythmias which may threaten health that are well-known or opaque. The purpose of this pilot study was to examine how different cardiac health risk factors rank together in association with arrhythmias in young, middle-aged, and older adults. Methods: The analytic sample included 101 adults aged 50.6 ± 22.6 years. Several prominent heart-health-related risk factors were self-reported. Mean arterial pressure and body mass index were collected using standard procedures. Hydraulic handgrip dynamometry measured strength capacity. A 6 min single-lead electrocardiogram evaluated arrhythmias. Respiratory sinus arrhythmias (RSAs) and ectopic heart beats were observed and specified for analyses. Classification and Regression Tree analyses were employed. Results: A mean arterial pressure ≥ 104 mmHg was the first level predictor for ectopic beats, while age ≥ 41 years was the first level predictor for RSAs. Age, heart rate, stress and anxiety, and physical activity emerged as important variables for ectopic beats (p < 0.05), whereas age, sodium, heart rate, and gender were important for RSAs (p < 0.05). Conclusions: RSAs and ectopic arrhythmias may have unique modifiable and non-modifiable factors that may help in understanding their etiology for prevention and treatment as appropriate across the lifespan.
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