Surgical Oncology-Oxford最新文献

{"title":"Mesenteric caudal right approach to the superior mesenteric artery in robotic pancreaticoduodenectomy","authors":"Yutaka Nakano, Yosuke Uematsu, Minoru Kitago, Yuko Kitagawa","doi":"10.1016/j.suronc.2025.102277","DOIUrl":"10.1016/j.suronc.2025.102277","url":null,"abstract":"","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102277"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of robotic and natural orifice transluminal endoscopic surgical technique procedures in patients undergoing sentinel lymph node biopsy during endometrial cancer surgery","authors":"Erkan Şimşek ,&nbsp;Sema Karakaş ,&nbsp;Onur Karaaslan ,&nbsp;Özge Akdeniz Yildiz ,&nbsp;Sadık Gündüz ,&nbsp;Gökhan Demirayak ,&nbsp;Cihan Comba ,&nbsp;İsa Aykut Özdemir ,&nbsp;Levent Yaşar","doi":"10.1016/j.suronc.2025.102282","DOIUrl":"10.1016/j.suronc.2025.102282","url":null,"abstract":"<div><h3>Objective</h3><div>The role of sentinel lymph node dissection in the surgical management of endometrial cancer limited to the uterus is gaining recognition. The safety and applicability of two methods were assessed by examining the results of our patients in the identification of the sentinel lymph node during endometrial cancer surgery. The methods were robotic surgery, a critical component of minimally invasive surgery, and the vNOTES (Natural Orifice Transluminal Endoscopic Surgery Technique), which has recently been introduced for malignant indications.</div></div><div><h3>Methods</h3><div>Patients who had endometrial cancer surgery at our center employing robotic and vNOTES technologies between January 2023 and June 2024 were included in this retrospective study. We conducted the dissection of sentinel lymph nodes utilizing a near-infrared technology camera method with indocyanine green (ICG) in both robotic and vNOTES techniques. The patients' records were retrospectively obtained from patient files and hospital records. Among the 76 patients who underwent surgery for endometrial cancer, 24 were treated with vNOTES surgery, whereas 52 received robotic surgery.</div></div><div><h3>Results</h3><div>No statistically significant differences were seen between the two groups for age (p = 0.447), body mass index (p = 0.506), prior abdominal operations (p = 0.209), predicted blood loss (p = 0.155), and surgical duration (p = 0.298). The detection rates of sentinel lymph nodes (SLN) were similar across the groups: 97 % (n = 50) in the robotic group and 96 % (n = 23) in the vNOTES group (p = 0.493). The only statistically significant difference was observed in postoperative pain scores at the 12th hour, which were lower in the vNOTES group (p = 0.023).</div></div><div><h3>Conclusion</h3><div>The vNOTES technique demonstrates comparable sentinel lymph node detection rates to robotic surgery in the management of uterine endometrial cancer. Moreover, it has the advantage of markedly less postoperative discomfort. vNOTES is a secure and efficacious minimally invasive option, especially for patients with comorbidities or those deemed unsuitable for robotic surgery.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102282"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144989978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and perioperative outcomes in extraperitoneal versus transperitoneal robot-assisted radical prostatectomy: A propensity score matching study from a single regional center","authors":"Atsushi Igarashi,&nbsp;Riki Obayashi,&nbsp;Akihiro Yamamoto,&nbsp;Akihiko Nagoshi,&nbsp;Tasuku Fujiwara,&nbsp;Naoki Akagi,&nbsp;Yuto Hattori,&nbsp;Noboru Shibasaki,&nbsp;Mutsushi Kawakita,&nbsp;Toshinari Yamasaki","doi":"10.1016/j.suronc.2025.102292","DOIUrl":"10.1016/j.suronc.2025.102292","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to compare perioperative outcomes and complications between the transperitoneal approach (Tp) and extraperitoneal approach (Ep) in robot-assisted radical prostatectomy (RARP) at our institution.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed data from 894 patients who underwent RARP between 2014 and 2023, including 539 with Ep and 355 with Tp. Ep was selected for patients who did not require extended lymph node dissection (ELND), whereas Tp was selected for patients who required ELND. Propensity score matching (PSM) was performed, resulting in 326 matched pairs. Primary outcomes included severe complications (Clavien–Dindo grade III or higher). Secondary outcomes included transfusion rates, console time without ELND and postoperative length of stay.</div></div><div><h3>Results</h3><div>Following PSM, severe complications occurred in 0 patients (0 %) in the Ep group and in 14 patients (4.3 %) in the Tp group, with bowel-related complications more frequent in the latter. The transfusion rate was low in both groups (0.6 % [Ep] vs. 0 % [Tp], p = 0.43). Operative parameters showed comparable console time without ELND (185 min [Ep] vs. 179 min [Tp], p = 0.30). Postoperative length of stay was comparable between groups (median, 6 days for both; p = 0.05). Peritoneal injuries occurred in 19 % of patients in the Ep group but did not lead to major complications or conversion to Tp in most cases.</div></div><div><h3>Conclusions</h3><div>This study suggests that both Tp and Ep are feasible approaches for RARP, with Ep potentially associated with fewer bowel complications.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102292"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145050166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of thoracic duct ligation for post-esophagectomy chylothorax in esophageal cancer: a nationwide inpatient cohort study","authors":"Takashi Shigeno ,&nbsp;Keisuke Okuno ,&nbsp;Taichi Ogo ,&nbsp;Toshiro Tanioka ,&nbsp;Kenro Kawada ,&nbsp;Hisashi Fujiwara ,&nbsp;Hiroyasu Kagawa ,&nbsp;Masanori Tokunaga ,&nbsp;Kiyohide Fushimi ,&nbsp;Yusuke Kinugasa","doi":"10.1016/j.suronc.2025.102279","DOIUrl":"10.1016/j.suronc.2025.102279","url":null,"abstract":"<div><h3>Background</h3><div>Recently, thoracic duct embolization (TDE) has been increasingly adopted as a first-line minimally invasive therapy for post-esophagectomy chylothorax instead of thoracoscopic thoracic duct ligation (TTDL). However, the therapeutic efficacy and advantages of TDE over TTDL are still controversial. This study aimed to evaluate and compare the clinical and financial outcomes of TDE and TTDL for post-operative chylothorax after esophagectomy using a national database.</div></div><div><h3>Methods</h3><div>We retrieved data from patients with esophageal cancer who underwent TDE (<em>n</em> = 312) or TTDL (<em>n</em> = 167) for chylothorax after esophagectomy between April 2012 and March 2022 from the Diagnosis Procedure Combination database in Japan. We compared the success rate of the first intervention, length of post-interventional hospital stay, and total hospitalization cost between the TDE and TTDL groups using propensity score matching analysis.</div></div><div><h3>Results</h3><div>The success rate of the first intervention was significantly higher in the TTDL group than in the TDE group (odds ratio, 6.13; 95 % confidence interval [CI], 3.25 to 11.55). The length of post-interventional hospital stay was significantly shorter (regression coefficient, −14.8 days; 95 % CI, −26.7 to −2.9) and the total hospitalization cost was significantly lower in the TTDL group than in the TDE group (regression coefficient, −1,258,212 yen; 95 % CI, −2,082,407 to −434,017).</div></div><div><h3>Conclusions</h3><div>This nationwide cohort study showed that TTDL was associated with a shorter length of post-interventional hospital stay, lower total hospitalization cost, and higher success rate of the first intervention than TDE for post-esophagectomy chylothorax.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102279"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145004385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-term surgical outcomes for colon adenocarcinoma: Racial-Ethnic comparisons in a universal access health system","authors":"Yvonne L. Eaglehouse ,&nbsp;Sarah Darmon ,&nbsp;Michele M. Gage ,&nbsp;Craig D. Shriver ,&nbsp;Kangmin Zhu","doi":"10.1016/j.suronc.2025.102295","DOIUrl":"10.1016/j.suronc.2025.102295","url":null,"abstract":"<div><h3>Background</h3><div>Access to care has been identified as a contributor to racial-ethnic differences in treatment receipt and survival of colon cancer in the U.S. Less is known about racial-ethnic differences in aspects and outcomes of colon cancer surgery and whether access to care plays a role. We aimed to study colon cancer surgery and short-term postoperative outcomes in the Military Health System (MHS), which provides access to care regardless of patient characteristics.</div></div><div><h3>Methods</h3><div>We used the MilCanEpi database to identify patients aged 18 or older who were diagnosed with stage I-III colon adenocarcinoma between 2001 and 2014 and received colectomy as treatment. Outcomes included positive surgical margins, inadequate lymphadenectomy (&lt;12 nodes examined), 30-day complications (any; general or gastrointestinal), and 30-day hospital readmissions. Multivariable Poisson regression models estimated the adjusted risk ratios (ARRs) and 95 % confidence intervals (CIs) in association with race-ethnicity for each outcome.</div></div><div><h3>Results</h3><div>The study included 157 Asian or Pacific Islander, 258 non-Hispanic Black, 111 Hispanic, and 1131 non-Hispanic White patients. Overall, the risk of measured outcomes did not differ significantly for racial-ethnic minority groups compared to non-Hispanic White (ARRs and their 95 % CIs included 1.00). By complication type, Hispanic patients had significantly lower risk of bowel obstruction (ARR = 0.55, 95 % CI = 0.32, 0.96) compared to non-Hispanic White patients, with no other statistically significant racial-ethnic differences.</div></div><div><h3>Conclusions</h3><div>In the universal access MHS, there were no overall significant racial-ethnic differences in surgical aspects or experience of 30-day outcomes of colectomy for non-metastatic colon cancer.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102295"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thirty-Five years of globalizing surgical oncology knowledge: A look into the future – IASGO Cairo 2024","authors":"Dan G. Duda ,&nbsp;Mohamed Abdel Wahab ,&nbsp;Kyoichi Takaori","doi":"10.1016/j.suronc.2025.102294","DOIUrl":"10.1016/j.suronc.2025.102294","url":null,"abstract":"","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102294"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications of ovarian metastases from well-differentiated small bowel neuroendocrine neoplasms: a focus on bowel and ureteral obstruction","authors":"Sydney J. Wellens ,&nbsp;Nicholas J. Skill ,&nbsp;Kevin M. Sullivan ,&nbsp;Mary A. Maluccio ,&nbsp;Kristen E. Limbach","doi":"10.1016/j.suronc.2025.102300","DOIUrl":"10.1016/j.suronc.2025.102300","url":null,"abstract":"<div><h3>Introduction</h3><div>Ovarian metastasis from small bowel neuroendocrine neoplasms (SBNENs) was traditionally considered rare, but more recent series have suggested a higher prevalence. This case series seeks to examine the features and outcomes of patients with neuroendocrine ovarian metastases (NOM).</div></div><div><h3>Methods</h3><div>Female patients with histologically confirmed well-differentiated SBNENs were identified using a prospectively maintained database (2014–2024). The electronic medical record was reviewed for details of diagnosis, histopathology, biomarkers, and outcomes among patients with and without NOM.</div></div><div><h3>Results</h3><div>175 patients met inclusion criteria. 35 patients (20 %) had ovarian metastasis; for this group, 31.4 % had small bowel obstruction only, 5.7 % had ureteral obstruction only, and 14.3 % had both SBO and ureteral obstruction. 22 (62.9 %) also had peritoneal metastasis. 13 patients had ovarian metastasis but no peritoneal metastasis; within this group, 38.5 % had SBO, 15.4 % had ureteral obstruction, 76.9 % developed carcinoid syndrome, and 7.69 % died. There were no significant differences in rate of SBO (p = 0.280), ureteral obstruction (p = 0.716), or death (p = 0.091) between those with ovarian metastasis only and those with peritoneal metastasis only. Median overall survival was not reached.</div></div><div><h3>Conclusion</h3><div>This case series of female patients with SBNENs represents one of the largest available in the literature and demonstrates high rates of complications for those with ovarian metastasis, even in the absence of peritoneal metastasis. Prophylactic oophorectomy may be considered for SBNEN patients given the known development of severe complications throughout the progression of this disease where expectation for survival is lengthy.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102300"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rectal cancer surgery timing after neoadjuvant therapy: balancing downstaging and perioperative outcomes","authors":"Giacomo Calini ,&nbsp;Alice Gori ,&nbsp;Claudio Isopi ,&nbsp;Antonino Spinelli ,&nbsp;Gianluca Pellino ,&nbsp;Matteo Fiore ,&nbsp;Alessandro Bianconi ,&nbsp;Stefano Cardelli ,&nbsp;Davide Ferrari ,&nbsp;Emanuele Rausa ,&nbsp;Gilberto Poggioli ,&nbsp;Matteo Rottoli ,&nbsp;the COVID-CRC Study Group.","doi":"10.1016/j.suronc.2025.102299","DOIUrl":"10.1016/j.suronc.2025.102299","url":null,"abstract":"<div><h3>Aim of the study</h3><div>Neoadjuvant therapy (NAT) and Total Mesorectal Excision (TME) improves oncological outcomes in locally advanced rectal cancer (LARC). We aimed to define the optimal timing for rectal resection and TME after NAT, balancing pathologic Complete Response (pCR) and downstaging with the fewest complications.</div></div><div><h3>Methods</h3><div>Stage I-III rectal cancer surgery preceded by NAT were retrieved from a retrospective collaborative of 81 centers in Italy 2018–2021. Logistic regression (LR) examined the independent association between postoperative outcomes (pCR, downstaging, intra- and postoperative complications, incomplete resection) and NAT protocols: chemoradiotherapy (nCRT) and short-course radiotherapy (S-CRT) stratified for timing (&lt;8w; 8-12w; &gt;12w) between NAT completion and surgery.</div></div><div><h3>Results</h3><div>Overall, 1428 patients were included: 1042 received nCRT, 187 SCRT, 125 long-course RT, and 74 others. Different timing of nCRT were not associated with any of the outcomes. Time interval &gt;12w for S-CRT was significantly and independently associated with pCR (OR 4.99, 95 %CI 1.4–18), but with similar downstaging, intra- and post-operative complications, and incomplete resection. LR predicting for pCR found a significant association with ASA≥3 (OR 0.67, 95 %CI 0.5–0.9) and with S-CRT &lt;8 weeks (OR 0.31, 95 %CI 0.13–0.74), while no variables were found to be associated with downstaging and intraoperative complications. Postoperative complications were associated with male, ASA≥3, and medium-low rectal cancer, while incomplete resection with ASA≥3, and BMI.</div></div><div><h3>Conclusion</h3><div>Unlike previous literature, the timing of nCRT was not associated with pCR, downstaging, intra- and postoperative complications, or incomplete resection. Timing &gt;12 weeks between SCRT completion and TME showed improved pCR with similar downstaging, intra- and post-operative complications, and incomplete resection.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102299"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overall survival improvement with locoregional control in patients with metastatic breast cancer. Single-institution experience","authors":"María Tereza Nieto-Coronel ,&nbsp;Nancy Reynoso-Noveron ,&nbsp;Ariana Tabares-Yañez ,&nbsp;Claudia Haydee Arce- Salinas","doi":"10.1016/j.suronc.2025.102304","DOIUrl":"10.1016/j.suronc.2025.102304","url":null,"abstract":"<div><h3>Background</h3><div>The benefit of local control on the overall survival of patients with metastatic breast cancer remains controversial. This study aimed to evaluate the impact of locoregional treatment of the primary tumor (surgery and/or radiotherapy) in Mexican patients diagnosed with de novo metastatic breast cancer.</div></div><div><h3>Materials and methods</h3><div>This retrospective study evaluated 671 patients with de novo metastatic breast cancer, diagnosed between the years 2007–2015, using data from a local database of breast cancer patients. The decision for locoregional treatment was made by the attending physician.</div></div><div><h3>Results</h3><div>Among 671 patients, the median follow-up was 26.83 months. Patients who underwent locoregional control (surgery and/or radiotherapy) had a median survival of 41.57 months compared to 21.3 months in those without locoregional control (p &lt; 0.001). Median survival was 51.5 months in patients treated with surgery versus 25,53 months in those without surgery (p &lt; 0.001) and 40.1 months versus 25.23 months in patients receiving chemoradiotherapy (p &lt; 0.001). Multivariate analysis confirmed that surgery significantly improved overall survival (HR 0.50; 95 % CI:0.32–0.77; p = 0.002). However, after adjusting for potential confounders using propensity score matching, the survival benefit associated with surgery did not reach statistical significance.</div></div><div><h3>Conclusions</h3><div>Our retrospective analysis shows no survival benefit from locoregional control after adjustment for potential confounders. However, given the observed survival differences, it is important to identify which patient subgroups may derive benefit in prospective studies.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102304"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current evidence for robotic and laparoscopic liver resections: Results from the international study group","authors":"Hwee-Leong Tan ,&nbsp;Darren W.Q. Chua ,&nbsp;Brian K.P. Goh","doi":"10.1016/j.suronc.2025.102238","DOIUrl":"10.1016/j.suronc.2025.102238","url":null,"abstract":"<div><div><span>Minimally-invasive liver resection<span> (MILR) has been increasingly adopted across the world with improvements in surgical technique and instrumentation. While MILR has been shown to confer several perioperative benefits compared to open liver resection, the steep learning curve associated with MILR remains a significant hurdle. Robotic liver resection (RLR) leverages on inherent technical advantages the robotic platform has over conventional </span></span>laparoscopy, holding the potential for RLR to achieve the perioperative advantages of MILR while overcoming the limitations of laparoscopic liver resection (LLR). In this review, we summarize the current evidence comparing the outcomes of RLR and LLR from the International Robotic and Laparoscopic Liver Resection Study Group.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"63 ","pages":"Article 102238"},"PeriodicalIF":2.4,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}