Journal of Arthroplasty最新文献

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Extended-Release Versus Immediate-Release Triamcinolone Acetonide in Patients Who Have Knee Osteoarthritis and Type 2 Diabetes Mellitus 膝关节骨性关节炎和 2 型糖尿病患者中的曲安奈德缓释剂与曲安奈德速释剂的比较
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-09-01 DOI: 10.1016/j.arth.2024.05.055
{"title":"Extended-Release Versus Immediate-Release Triamcinolone Acetonide in Patients Who Have Knee Osteoarthritis and Type 2 Diabetes Mellitus","authors":"","doi":"10.1016/j.arth.2024.05.055","DOIUrl":"10.1016/j.arth.2024.05.055","url":null,"abstract":"<div><h3>Background</h3><p>Intra-articular corticosteroid injections may cause hyperglycemia (glucose level &gt;180 mg/dL). In a phase 2 study of 33 patients who had osteoarthritis of the knee and type 2 diabetes mellitus, triamcinolone acetonide extended-release (TA-ER) was associated with minimal glycemic control disruption compared with triamcinolone acetonide immediate-release (TA-IR). This <em>post hoc</em> analysis characterizes the clinical relevance of these results.</p></div><div><h3>Methods</h3><p>Patients who had symptomatic osteoarthritis of the knee for ≥6 months, type 2 diabetes mellitus for ≥1 year, and hemoglobin A1c ≥6.5 and ≤9.0% were randomized to receive an intra-articular injection of either TA-ER or TA-IR. Changes in continuous glucose monitor daily glucose level, percentage of time in or above the target glucose range (&gt;70 to 180 mg/dL), time to glucose level 250 mg/dL and maximum glucose level &gt;250 mg/dL, and glycemic variability were evaluated.</p></div><div><h3>Results</h3><p>Across postinjection days 1 to 3, the TA-ER group (n = 18) had a lower median change from baseline in maximum glucose level (92.3 versus 169.1 mg/dL), a reduced percentage of time with a glucose level &gt;250 mg/dL (12 versus 26%), a smaller proportion of patients who had a maximum glucose level &gt;250 mg/dL (50 versus 93%), and a greater percentage of time in the target glucose range (62 versus 48%) versus the TA-IR group (n = 15). There was less glycemic variability and lower glucose spikes in the TA-ER versus TA-IR group. Median times to glucose level 250 mg/dL (44 versus 6 hours) and maximum glucose level (34 versus 13 hours) were significantly longer in the TA-ER versus TA-IR group.</p></div><div><h3>Conclusions</h3><p>Use of TA-ER was associated with a clinically meaningful reduction in hyperglycemia versus TA-IR.</p></div>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883540324005278/pdfft?md5=3539f3a560adcc6a2bf62426b1952154&pid=1-s2.0-S0883540324005278-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141181324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Approach and Body Mass Index Impact Risk of Wound Complications Following Total Hip Arthroplasty 手术方式和体重指数对全髋关节置换术后伤口并发症风险的影响
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-09-01 DOI: 10.1016/j.arth.2024.03.047
{"title":"Surgical Approach and Body Mass Index Impact Risk of Wound Complications Following Total Hip Arthroplasty","authors":"","doi":"10.1016/j.arth.2024.03.047","DOIUrl":"10.1016/j.arth.2024.03.047","url":null,"abstract":"<div><h3>Background</h3><p>Previous studies have suggested that wound complications may differ by surgical approach after total hip arthroplasty (THA), with particular attention toward the direct anterior approach (DAA). However, there is a paucity of data documenting wound complication rates by surgical approach and the impact of concomitant patient factors, namely body mass index (BMI). This investigation sought to determine the rates of wound complications by surgical approach and identify BMI thresholds that portend differential risk.</p></div><div><h3>Methods</h3><p>This multicenter study retrospectively evaluated all primary THA patients from 2010 to 2023. Patients were classified by skin incision as having a laterally based approach (posterior or lateral approach) or DAA (longitudinal incision). We identified 17,111 patients who had 11,585 laterally based (68%) and 5,526 (32%) DAA THAs. The mean age was 65 years (range, 18 to 100), 8,945 patients (52%) were women, and the mean BMI was 30 (range, 14 to 79). Logistic regression and cut-point analyses were performed to identify an optimal BMI cutoff, overall and by approach, with respect to the risk of wound complications at 90 days.</p></div><div><h3>Results</h3><p>The 90-day risk of wound complications was higher in the DAA group versus the laterally based group, with an absolute risk of 3.6% versus 2.6% and a multivariable adjusted odds ratio of 1.5 (<em>P</em> &lt; .001). Cut-point analyses demonstrated that the risk of wound complications increased steadily for both approaches, but most markedly above a BMI of 33.</p></div><div><h3>Conclusions</h3><p>Wound complications were higher after longitudinal incision DAA THA compared to laterally based approaches, with a 1% higher absolute risk and an adjusted odds ratio of 1.5. Furthermore, BMI was an independent risk factor for wound complications regardless of surgical approach, with an optimal cut-point BMI of 33 for both approaches. These data can be used by surgeons to help consider the risks and benefits of approach selection.</p></div><div><h3>Level of Evidence</h3><p>Level III.</p></div>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883540324002638/pdfft?md5=d68e4f112d0d7f8e28acbcac4eba97b6&pid=1-s2.0-S0883540324002638-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obesity and Primary Total Hip Arthroplasty: The Absolute versus Relative Risk of Periprosthetic Joint Infection at 15 Years 肥胖与原发性全髋关节置换术:15年后假体周围关节感染的绝对风险与相对风险。
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-09-01 DOI: 10.1016/j.arth.2024.03.033
{"title":"Obesity and Primary Total Hip Arthroplasty: The Absolute versus Relative Risk of Periprosthetic Joint Infection at 15 Years","authors":"","doi":"10.1016/j.arth.2024.03.033","DOIUrl":"10.1016/j.arth.2024.03.033","url":null,"abstract":"<div><h3>Background</h3><p>To make an informed decision about total hip arthroplasty (THA), surgeons and patients need to understand the absolute and relative risks of periprosthetic joint infection (PJI). We sought to evaluate the long-term risk of PJI following primary THA stratified by body mass index (BMI) and PJI-related risk factors.</p></div><div><h3>Methods</h3><p>We identified 21,550 primary THAs performed from 2000 to 2021 at a single institution. Patients were stratified as having 0, 1, or ≥ 2 PJI risk factors (diabetes, chronic kidney disease, nonprimary osteoarthritis, immunosuppression, or active smoking) and into BMI categories. The 15-year cumulative risk of PJI was evaluated by BMI and PJI risk factors.</p></div><div><h3>Results</h3><p>For the entire cohort, the 15-year absolute risk of PJI was 2%. For patients who did not have PJI risk factors, the absolute risk of PJI at 15 years was 1% in normal weight, 2% in class III obesity, and 4% in class IV obesity. Patients who had class III and IV obesity had a 3-times and 9-times higher relative risk of PJI, respectively (<em>P</em> = .03, <em>P</em> &lt; .001). Among patients who had ≥ 2 PJI risk factors, the absolute risk of PJI at 15 years was 2% in normal weight, 4% in class III obesity, and 18% in class IV obesity.</p></div><div><h3>Conclusions</h3><p>Healthy patients who had class III and IV obesity had a 3-times and 9-times increased risk of PJI at 15 years relative to normal weight patients. However, the absolute risk of PJI at 15 years was 2 and 4%, respectively. Given emerging data questioning whether BMI modification decreases PJI risk, surgeons and patients must consider both a 3-times to 9-times increased relative risk of PJI and a 2 to 4% absolute risk of PJI at 15 years for healthy patients who had a BMI ≥ 40.</p></div><div><h3>Level of evidence</h3><p>IV.</p></div>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883540324002493/pdfft?md5=7af5e86b1c8f80c06853418f1905a011&pid=1-s2.0-S0883540324002493-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140195028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic Anticoagulation is Associated With Increased Risk for Postoperative Complications Following Aseptic Revision Total Hip Arthroplasty 长期抗凝与无菌翻修全髋关节置换术后并发症风险增加有关。
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-09-01 DOI: 10.1016/j.arth.2024.01.020
{"title":"Chronic Anticoagulation is Associated With Increased Risk for Postoperative Complications Following Aseptic Revision Total Hip Arthroplasty","authors":"","doi":"10.1016/j.arth.2024.01.020","DOIUrl":"10.1016/j.arth.2024.01.020","url":null,"abstract":"<div><h3>Background</h3><p>With an aging global population, the incidence of revision total hip arthroplasty (rTHA) is expected to increase markedly. While patients undergoing primary total hip arthroplasty who require chronic anticoagulation (AC) have been associated with increased postoperative complications, less is known about the impact of chronic AC status on postoperative complications in the rTHA setting. This study sought to compare complication rates following aseptic rTHA between patients who were on chronic AC and those who were not.</p></div><div><h3>Methods</h3><p>A large national database was utilized to retrospectively identify 9,421 patients who underwent aseptic rTHA between 2014 and 2019. Patients were divided into 2 cohorts: 1,790 patients (19.0%) were in the chronic AC cohort (ie, having an AC prescription filled within 6 months prior to and following rTHA), and 7,631 patients (81.0%) were not on chronic AC. Postoperative complications at 90-days and 2-years were compared between cohorts utilizing univariate and multivariate analyses, controlling for sex, age, and comorbidities.</p></div><div><h3>Results</h3><p>At 90-days, chronic AC patients had increased odds of prosthetic joint infections (PJIs) (odds ratio [OR] 3.2, <em>P</em> &lt; .001), surgical site infections (OR 3.6, <em>P</em> &lt; .001), and mechanical prosthetic complications (OR 3.5, <em>P</em> &lt; .001), which included any aseptic loosening, implant dislocation, or broken prosthetic. At 2-years, chronic AC patients had increased odds of PJI (OR 3.3, <em>P</em> &lt; .001) as well as mechanical prosthetic complications (OR 3.2, <em>P</em> &lt; .001). Chronic AC patients were also at increased risk for reoperation within 2 years after initial aseptic rTHA (OR 1.9, <em>P</em> &lt; .001).</p></div><div><h3>Conclusions</h3><p>Patients on chronic AC have significantly higher odds of 90-day and 2-year complications after aseptic rTHA. This includes increased odds of PJI, surgical site infection, and mechanical prosthetic complications. Patients receiving chronic AC who undergo rTHA should be counseled on the risk-benefit ratio of their chronic AC status in a multidisciplinary setting to optimize their postoperative outcomes.</p></div>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883540324000202/pdfft?md5=0a8f61a7211347127727b170b53ff0b6&pid=1-s2.0-S0883540324000202-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative Cefazolin for Total Joint Arthroplasty Patients Who Have a Penicillin Allergy: Is It Safe? 对青霉素过敏的全关节置换术患者围手术期使用头孢唑啉:安全吗?
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-09-01 DOI: 10.1016/j.arth.2024.04.058
{"title":"Perioperative Cefazolin for Total Joint Arthroplasty Patients Who Have a Penicillin Allergy: Is It Safe?","authors":"","doi":"10.1016/j.arth.2024.04.058","DOIUrl":"10.1016/j.arth.2024.04.058","url":null,"abstract":"<div><h3>Background</h3><p>Cefazolin is the standard of care for perioperative antibiotic prophylaxis in total joint arthroplasty (TJA) in the United States. The potential allergic cross-reactivity between cefazolin and penicillin causes uncertainty regarding optimal antibiotic choice in patients who have a reported penicillin allergy (rPCNA). The purpose of this study was to determine the safety of perioperative cefazolin in PCNA patients undergoing primary TJA.</p></div><div><h3>Methods</h3><p>We identified all patients (n = 49,842) undergoing primary total hip arthroplasty (n = 25,659) or total knee arthroplasty (n = 24,183) from 2016 to 2022 who received perioperative intravenous antibiotic prophylaxis. Patients who had an rPCNA (n = 5,508) who received cefazolin (n = 4,938, 89.7%) were compared to rPCNA patients who did not (n = 570, 10.3%), and to patients who did not have an rPCNA (n = 43,359). The primary outcome was the rate of allergic reactions within 72 hours postoperatively. Secondary outcomes included the rates of superficial infections, deep infections, and <em>Clostridioides difficile</em> infections within 90 days.</p></div><div><h3>Results</h3><p>The rate of allergic reactions was 0.1% (n = 5) in rPCNA patients who received cefazolin, compared to 0.2% (n = 1) in rPCNA patients who did not (<em>P</em> = .48) and 0.02% (n = 11) in patients who have no rPCNA (<em>P</em> = .02). Allergic reactions were mild in all 5 rPCNA patients who received cefazolin and were characterized by cutaneous symptoms (n = 4) or dyspnea in the absence of respiratory distress (n = 1) that resolved promptly with antibiotic discontinuation and administration of antihistamines and/or corticosteroids. We observed no differences in the rates of superficial infections (0.1 versus 0.2%, <em>P</em> = .58), deep infections (0.3 versus 0.4%, <em>P</em> = .68), or <em>C difficile</em> infections (0.04% versus 0%, <em>P</em> = .99) within 90 days in rPCNA patients who received cefazolin versus alternative perioperative antibiotics.</p></div><div><h3>Conclusions</h3><p>In this series of more than 5,500 patients who had an rPCNA undergoing primary TJA, perioperative prophylaxis with cefazolin resulted in a 0.1% incidence of allergic reactions that were clinically indolent. Cefazolin can be safely administered to most patients, independent of rPCNA severity.</p></div><div><h3>Level of Evidence</h3><p>III.</p></div>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883540324003814/pdfft?md5=1f43d57bd9ff37c9881220ed6e06a00e&pid=1-s2.0-S0883540324003814-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140788247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early Versus Late Periprosthetic Joint Infection After Total Knee Arthroplasty: Do Patient Differences Exist? 全膝关节置换术后早期与晚期假体周围感染:患者是否存在差异?
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-09-01 DOI: 10.1016/j.arth.2024.04.061
{"title":"Early Versus Late Periprosthetic Joint Infection After Total Knee Arthroplasty: Do Patient Differences Exist?","authors":"","doi":"10.1016/j.arth.2024.04.061","DOIUrl":"10.1016/j.arth.2024.04.061","url":null,"abstract":"<div><h3>Background</h3><p>Periprosthetic joint infection (PJI) is a devastating complication following total knee arthroplasty (TKA). Little evidence exists comparing those with early versus late PJI. The purpose of the study was to determine comorbidity profile differences between patients developing early and late PJI.</p></div><div><h3>Methods</h3><p>There were 72,659 patients undergoing primary TKA from 2009 to 2021, who were identified from a commercial claims and encounters database. Subjects diagnosed with PJI were categorized as either ‘early’ (within 90 days of index procedure) or ‘late’ (&gt; 2 years after index arthroplasty). Non-infected patients within these periods served as control groups following 4:1 propensity score matching on other extraneous variables. Logistic regression analyses were performed comparing comorbidities between groups.</p></div><div><h3>Results</h3><p>Patients were significantly younger in the late compared to the early infection group (58.1 versus 62.4 years, <em>P</em> &lt; .001). When compared to those with early PJI, patients who had chronic kidney disease (13.3 versus 4.1%; OR [odds ratio] 5.17, <em>P</em> = .002), malignancy (20.4 versus 10.5%; OR 2.53, <em>P</em> = .009), uncomplicated diabetes (40.8 versus 30.6%; OR 2.00, <em>P</em> = .01), rheumatoid arthritis (9.2 versus 3.3%; OR 2.66, <em>P</em> = .046), and hypertension (88.8 versus 81.6%; OR 2.17, <em>P</em> = .04), were all significant predictors of developing a late PJI.</p></div><div><h3>Conclusions</h3><p>When compared to patients diagnosed with early PJI following primary TKA, the presence of chronic kidney disease, malignancy, uncomplicated diabetes, rheumatoid arthritis, and hypertension, were independent risk factors for the development of late PJI. Younger patients who have these comorbidities may be targets for preoperative optimization interventions that minimize the risk of PJI.</p></div>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S088354032400384X/pdfft?md5=6c89667ad56dd683263fd16769d1a342&pid=1-s2.0-S088354032400384X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140797490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing Rates of Minimal Clinically Important Difference Between Manual and Robotic-Assisted Total Knee Arthroplasty. 比较人工和机器人辅助全膝关节置换术的最小临床重要差异率
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-08-30 DOI: 10.1016/j.arth.2024.08.039
Marcos R Gonzalez, Perry L Lim, Antonia F Chen, Christopher M Melnic, Hany S Bedair
{"title":"Comparing Rates of Minimal Clinically Important Difference Between Manual and Robotic-Assisted Total Knee Arthroplasty.","authors":"Marcos R Gonzalez, Perry L Lim, Antonia F Chen, Christopher M Melnic, Hany S Bedair","doi":"10.1016/j.arth.2024.08.039","DOIUrl":"https://doi.org/10.1016/j.arth.2024.08.039","url":null,"abstract":"<p><strong>Background: </strong>Differences in patient-reported outcome measures (PROMs) between manual total knee arthroplasty (mTKA) and robotic-assisted TKA (rTKA) have not been adequately assessed. We compared the minimal clinically important difference for improvement (MCID-I) and Worsening (MCID-W) between mTKA and rTKA patients.</p><p><strong>Methods: </strong>Patients who underwent primary TKA (874 mTKA, 439 rTKA) with complete pre-operative and one-year post-operative PROMs were retrospectively identified using a multi-hospital joint arthroplasty registry. Patient-Reported Outcomes Measurement Information System Physical Function Short Form 10a (PROMIS PF-10a), PROMIS Global - Physical, or Knee Injury and Osteoarthritis Outcome Score-Physical Function Short Form (KOOS-PS) were collected. The MCID-I, MCID-W, and \"no significant change\" rates were calculated using distribution-based methods. Propensity-score matching was performed to control for confounding.</p><p><strong>Results: </strong>Similar 90-day pulmonary embolism (P = 0.26), deep venous thrombosis (P = 0.67), and emergency department visit (P = 0.35) rates were found. The 90-day readmission rate for mTKA was 1.7 and 3.4% for rTKA (P = 0.08), and overall revision rates were 2.2% for mTKA and 0.7% for rTKA (P = 0.07). Revision-free survival was 99% at one and two years for both groups (P = 0.65 and P = 0.43, respectively). There were no differences in the proportion of patients achieving MCID-I or MCID-W for PROMIS PF-10a, PROMIS Global - Physical, or KOOS-PS. The MCID-I for PROMIS PF-10a was achieved in 65.5 and 62.2% of patients who had mTKA and rTKA, respectively (P = 0.32).</p><p><strong>Conclusion: </strong>Our study demonstrated similar complication rates, and MCID-I and MCID-W attainment rates between mTKA and rTKA patients. Future studies should assess MCID attainment rates in the long term and in larger cohorts, comparing mTKA and rTKA.</p>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revision Total Knee Arthroplasty Achieves Minimal Clinically Important Difference Faster than Primary Total Knee Arthroplasty. 翻修全膝关节置换术比初次全膝关节置换术更快实现最小临床重要差异。
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-08-30 DOI: 10.1016/j.arth.2024.08.038
Perry L Lim, Arun R Kumar, Christopher M Melnic, Hany S Bedair
{"title":"Revision Total Knee Arthroplasty Achieves Minimal Clinically Important Difference Faster than Primary Total Knee Arthroplasty.","authors":"Perry L Lim, Arun R Kumar, Christopher M Melnic, Hany S Bedair","doi":"10.1016/j.arth.2024.08.038","DOIUrl":"https://doi.org/10.1016/j.arth.2024.08.038","url":null,"abstract":"<p><strong>Introduction: </strong>Revision total knee arthroplasty (rTKA) remains underexplored regarding patient-reported outcome measures (PROMs), particularly in terms of time to reach Minimal Clinically Important Difference (MCID). This study addresses this gap by comparing the time to achieve MCID between primary TKA (pTKA) and rTKA patients, providing valuable insights into their recovery trajectories.</p><p><strong>Methods: </strong>A total of 8,266 TKAs (7,618 pTKA and 648 rTKA) were retrospectively studied in a multi-institutional arthroplasty registry. Patients who completed the Patient-Reported Outcomes Measurement Information System (PROMIS) Global Physical, PROMIS Physical Function Short Form 10a (PF-10a), and Knee Injury and Osteoarthritis Outcome Score-Physical Function Short Form (KOOS-PS) questionnaires were identified by Current Procedural Terminology (CPT) codes. Survival curves with and without interval-censoring were utilized to evaluate the time to achieve MCID.</p><p><strong>Results: </strong>Comparing the time to achieve MCID, rTKAs were significantly faster than pTKA for PROMIS Global Physical (3.5 versus 3.7 months, P = 0.004) and KOOS-PS (3.3 versus 4.2 months, P < 0.001), but similar for PROMIS PF-10a (4.4 versus 4.8 months, P = 0.057). Interval-censoring also showed similar trends with earlier times to achieve MCID for rTKAs for PROMIS Global Physical (0.6 to 0.61 versus 0.97 to 0.97 months, P = 0.009) and KOOS-PS (0.97 to 0.97 versus 1.47 to 1.47 months, P < 0.001), but not for PROMIS PF-10a (2.43 to 2.54 versus 1.90 to 1.91 months, P = 0.92).</p><p><strong>Conclusion: </strong>The present study revealed that the time to achieve MCID was faster in patients undergoing rTKA compared to those undergoing pTKA. These findings allow surgeons to reassure preoperative revision TKA patients that their recovery to a minimal clinically important difference postoperatively may be quicker than expected, especially when compared to their initial recovery after primary TKA.</p>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to 'Synovial Calprotectin is Superior to Synovial Leukocyte Count in Excluding Chronic Periprosthetic Joint Infections, a Retrospective Cohort Study' The Journal of Arthroplasty 39 (2024) 1926-1931. 在排除慢性假体周围关节感染方面,滑膜钙蛋白优于滑膜白细胞计数,一项回顾性队列研究》的更正 《关节成形术杂志》39 (2024) 1926-1931。
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-08-29 DOI: 10.1016/j.arth.2024.08.009
Mohammed F Alkadhem, Harmen Ettema, Lucie M F Wagenmakers-Huizenga, Joris J W Ploegmakers, Anneke C Muller Kobold, Marjan Wouthuyzen-Bakker
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引用次数: 0
Readmissions at Thirty-Days and One-Year for Implant-Associated Complications following Primary Total Hip and Knee Arthroplasty: A Population-Based Study of 34,392 Patients Across Austria. 初次全髋关节和膝关节置换术后三十天和一年内因植入相关并发症再次入院的情况:以奥地利 34,392 名患者为对象的人群研究。
IF 3.4 2区 医学
Journal of Arthroplasty Pub Date : 2024-08-28 DOI: 10.1016/j.arth.2024.08.027
Maria Anna Smolle, Stefan Fischerauer, Ines Vukic, Florian Alexander Wenzl, Lukas Leitner, Andreas Leithner, Patrick Sadoghi
{"title":"Readmissions at Thirty-Days and One-Year for Implant-Associated Complications following Primary Total Hip and Knee Arthroplasty: A Population-Based Study of 34,392 Patients Across Austria.","authors":"Maria Anna Smolle, Stefan Fischerauer, Ines Vukic, Florian Alexander Wenzl, Lukas Leitner, Andreas Leithner, Patrick Sadoghi","doi":"10.1016/j.arth.2024.08.027","DOIUrl":"https://doi.org/10.1016/j.arth.2024.08.027","url":null,"abstract":"<p><strong>Introduction: </strong>The primary aim of this study was to assess 30-day and one-year rates for unplanned readmission due to implant-associated complications following total hip (THA) or total knee arthroplasty (TKA) in Austria. Secondary endpoints were reasons for readmission and differences in revision risk depending on demographics and hospital size.</p><p><strong>Methods: </strong>Data on patients receiving THA (n = 18,508) or TKA (n = 15,884) in orthopaedic and trauma units across Austria within a one-year period (January 2021 to December 2021) was retrieved from a government-maintained database. The absolute and relative frequencies of unplanned readmissions were calculated. Risk factors for 30-day and one-year readmission following THA or TKA due to implant-associated complications were investigated.</p><p><strong>Results: </strong>The thirty-day and one-year readmission rates for any implant-associated complication were 1.0% (339 of 34,392) and 3.0% (1,024 of 34,392). Relative to the overall readmission rate for any complication at 30 days (n = 1,952) and one year (n = 12,109), respectively, readmission rates for implant-associated complications were 17.4 and 8.5%. The thirty-day readmission rates were higher in THA (1.2%) than TKA patients (0.8%; P = 0.001), while it was the opposite at one year (THA, 2.7%; TKA, 3.3%; P < 0.001). Mechanical complications (554 of 1,024) were the most common reason for one-year readmission. Prolonged length of in-hospital stay independently associated with increased one-year readmission risk in THA and TKA patients. Treatment at large-sized hospitals was associated with a higher one-year readmission risk in TKA patients.</p><p><strong>Conclusions: </strong>The thirty-day and one-year readmission rates for implant-associated complications following THA or TKA in Austria are lower than reported in other countries, with similar risk factors and reasons for readmission. Considering that almost 20% of unplanned hospital readmissions following total joint arthroplasty are attributable to implant-associated complications, optimization of in-hospital and post-discharge medical care for these patients is warranted.</p>","PeriodicalId":51077,"journal":{"name":"Journal of Arthroplasty","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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