Tarquin Boca, Salomon Y. Cohen, Elsabeth Hermouet, M. Srour, A. Miere
{"title":"Benign Lobular Inner Nuclear Layer Proliferation associated with Congenital Hypertrophy of the Retinal Pigment Epithelium","authors":"Tarquin Boca, Salomon Y. Cohen, Elsabeth Hermouet, M. Srour, A. Miere","doi":"10.1097/icb.0000000000001599","DOIUrl":"https://doi.org/10.1097/icb.0000000000001599","url":null,"abstract":"\u0000 \u0000 To report two cases of benign intraretinal tumors of the inner nuclear layer (INL) associated with congenital hypertrophy of the retinal pigment epithelium (CHRPE).\u0000 \u0000 \u0000 \u0000 Multimodal imaging of two cases, including fundus color and autofluorescence photography, structural and en face spectral-domain optical coherence tomography (SD-OCT), OCT-angiography, fluorescein and indocyanine green angiography.\u0000 \u0000 \u0000 \u0000 During a routine examination, intraretinal tumors of the INL associated with several CHRPE lesions were observed in one eye of two male patients, aged 27 and 32 years, respectively. Multimodal imaging showed white multifocal lobulated lesions with arching extensions, located in the INL, which allowed diagnosing benign lobular inner nuclear layer proliferation (BLIP).\u0000 \u0000 \u0000 \u0000 BLIP is a rare benign tumor located in the INL with a unique pattern and only 4 cases have been reported to date. The present two cases allowed confirming that BLIP is associated with CHRPE, suggesting a concomitant developmental anomaly of the RPE and the inner retina.\u0000","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":" 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141000982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasmine Alcibahy, Nicola Ghazi, Arif O. Khan, Aniruddha Agarwal
{"title":"Surgical repair of macular fold in X-linked retinoschisis initially misdiagnosed as familial exudative vitreoretinopathy","authors":"Yasmine Alcibahy, Nicola Ghazi, Arif O. Khan, Aniruddha Agarwal","doi":"10.1097/icb.0000000000001600","DOIUrl":"https://doi.org/10.1097/icb.0000000000001600","url":null,"abstract":"\u0000 \u0000 To describe the presentation and surgical management of a young boy initially thought to have familial exudative vitreoretinopathy who was ultimately diagnosed with an unusually aggressive form of X-linked retinoschisis that included rapidly progressive bullous retinoschisis and tractional macular fold.\u0000 \u0000 \u0000 \u0000 Retrospective case report\u0000 \u0000 \u0000 \u0000 A 19-month-old boy with straightening of major arcades, peripheral retinal ischemia, and in the left eye, a large macular fold was initially diagnosed as familial exudative vitreoretinopathy. During follow-up, he developed a rapidly progressive bullous retinoschisis in the left eye involving the inferior macula extending superiorly up to the macular fold. This revised the working diagnosis to X-linked retinoschisis, which was confirmed by genetic testing. Pars plana vitrectomy, inner flap retinectomy, unrolling of the macular fold and inner flap retinectomy, and C3F8 gas tamponade were performed. This resolved the macular fold. The patient showed good anatomical results without surgical complications up to 18 months of post-operative follow-up.\u0000 \u0000 \u0000 \u0000 X-linked retinoschisis can rarely present in young children with macular fold and peripheral ischemia, mimicking familial exudative vitreoretinopathy. Rapidly progressive bullous retinoschisis in this setting can be treated with pars plana vitrectomy, inner wall retinectomy, and removal of the vitreous traction to improve visual prognosis.\u0000","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":"24 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141005658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical and Optical Coherence Tomography Features of Subretinal Fibrin Glue after Glue-Assisted Vitrectomy for Rhegmatogenous Retinal Detachment Repair. GUARD Study – Report 3:","authors":"Aiswarya Ramachandran, SriniVas Sadda, Mudit Tyagi","doi":"10.1097/icb.0000000000001598","DOIUrl":"https://doi.org/10.1097/icb.0000000000001598","url":null,"abstract":"\u0000 \u0000 To highlight the clinical and optical coherence tomography (OCT) features of subretinal fibrin glue and its resolution over time in patients who have undergone glue- assisted retinopexy for Rhegmatogenous Retinal Detachments (RRD).\u0000 \u0000 \u0000 \u0000 A report of 2 cases with subretinal migration of fibrin glue. Both the cases were assessed with clinical examination, serial fundus photos and serial OCT scans through the area of subretinal fibrin immediately after surgery, at 1 week, 2 weeks and at 6 weeks.\u0000 \u0000 \u0000 \u0000 In both the cases of intraoperative subretinal glue migration during glue-assisted vitrectomy for RRD repair, the subretinal glue had a characteristic appearance and course of evolution. On examination and color photography, the glue had an amorphous whitish appearance with wispy edges. This corresponded to subretinal hyperreflective material (SHRM) on OCT with a layered appearance. By two weeks after surgery, the subretinal glue demonstrated substantial regression on retinal examination and on OCT scans. At 6 weeks visit, the entire glue was noted to be resorbed along with an intact photoreceptor outer segments/Ellipsoid Zone layer\u0000 \u0000 \u0000 \u0000 In summary, this report describes the clinical and OCT appearance of subretinal migration of fibrin glue. Subretinal fibrin appears whitish on examination and corresponds to layered SHRM without shadowing on OCT. It appears to resorb spontaneously within weeks with apparent recovery of the overlying photoreceptors.\u0000","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":"10 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141004635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined Amniotic Membrane Graft and Autologous Retinal Transplant for Repair of Refractory Chronic Myopic Macular Holes","authors":"Z. Tauqeer, Jong Park, Tamer H Mahmoud","doi":"10.1097/icb.0000000000001588","DOIUrl":"https://doi.org/10.1097/icb.0000000000001588","url":null,"abstract":"\u0000 \u0000 To report a technique for reconstruction of large, persistent, chronic, myopic macular holes using a combined human amniotic membrane graft and autologous retinal transplant (AMN-ART).\u0000 \u0000 \u0000 \u0000 Three patients with large, myopic macular holes that failed prior surgical attempts and underwent subretinal amniotic membrane graft with overlying autologous retinal transplant and short-term perfluorocarbon tamponade. Pre- and postoperative visual acuity (VA) and images were analyzed at 3, 6, and 9 months.\u0000 \u0000 \u0000 \u0000 All 3 myopic macular holes remained closed at 9 months with resolution of central scotoma. The first case, a 69-year-old female, presented with a persistent macular hole whose minimum linear diameter was 1085 μm. Her pre-op VA of 20/200 improved by 9 months to 20/100. Secondly, a 72-year-old male with history of recurrent retinal detachment repair with silicone oil and persistent macular hole of 1134 μm presented with pre-op VA of 20/200, which was unchanged at 9 months. Lastly, a 76-year-old female with a persistent macular hole of 935 μm with preop VA of 20/80 improved by 9 months post-op to 20/50. No complications were encountered related to the grafts.\u0000 \u0000 \u0000 \u0000 Combined AMN-ART may provide a surgical option for repair of refractory, large, chronic myopic macular holes with underlying atrophy.\u0000","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":"65 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141021883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Manousakis, P. Gartaganis, Emmanouil Manousakis, Efthymios Karmiris
{"title":"A Novel Technique for scleral fixation of Carlevale Intraocular Lens without conjunctival opening utilizing Hoffman Pockets","authors":"E. Manousakis, P. Gartaganis, Emmanouil Manousakis, Efthymios Karmiris","doi":"10.1097/icb.0000000000001584","DOIUrl":"https://doi.org/10.1097/icb.0000000000001584","url":null,"abstract":"\u0000 \u0000 To report a novel surgical technique for scleral fixation of Carlevale intraocular lens (IOL) without conjunctival dissection using Hoffman pockets.\u0000 \u0000 \u0000 \u0000 An 80-years-old female with IOL dislocation in her right eye required IOL exchange. After removing the dislocated IOL, a Carlevale IOL was implanted, securing the self-blocking harpoons within scleral pockets which were constructed using Hoffman technique.\u0000 \u0000 \u0000 \u0000 Surgical procedure was uneventful. During the next 3 months follow up, Carlevale IOL remained stable within the scleral pockets, and no signs of IOL dislocation or decentration were observed. Visual acuity significantly improved from 20/200 preoperatively up to 20/32 postoperatively due to corneal scaring from previous herpetic keratitis. No postoperative complications were recorded.\u0000 \u0000 \u0000 \u0000 Creating scleral pockets without conjunctival dissection using Hoffman pockets technique, represent a reliable and effective method for achieving both secure fixation and effective scleral covering of Carlevale IOL haptics. Absence of conjunctival opening, apart from patient postoperative comfort, reduces risk of postoperative complications, including conjunctival erosion and infection. The presented technique offers a promising alternative for Carlevale IOL scleral fixation.\u0000","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":"34 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140709619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masahiro Akada, Yuki Muraoka, Kenji Ishihara, S. Morooka, Masayuki Hata, A. Tsujikawa
{"title":"An Unusual Chorioretinal Manifestation of Relapsing Polychondritis Coexisting with Scleritis: A Case Report","authors":"Masahiro Akada, Yuki Muraoka, Kenji Ishihara, S. Morooka, Masayuki Hata, A. Tsujikawa","doi":"10.1097/icb.0000000000001582","DOIUrl":"https://doi.org/10.1097/icb.0000000000001582","url":null,"abstract":"\u0000 \u0000 To report an atypical chorioretinal manifestation concomitant with severe scleritis in a patient diagnosed with relapsing polychondritis.\u0000 \u0000 \u0000 \u0000 A 53-year-old male, with a six-month history of recurrent bilateral auricular cartilage inflammation was admitted to our hospital. Clinical and pathological examinations of the auricular cartilage led to the diagnosis of relapsing polychondritis.\u0000 \u0000 \u0000 \u0000 Ophthalmological examination revealed a localized elevation in the superonasal quadrant of the left fundus, where the scleritis was more severe than in other regions. B-mode ultrasonography revealed choroidal thickening and subretinal lesions in this area, along with a white retinal lesion identified during the fundus examination. Further investigation using optical coherence tomography (OCT) unveiled subretinal and retinal lesions in the same region, with dispersed cells into the vitreous cavity in a fountain-like pattern. After treatment with systemic corticosteroids and cyclophosphamide, there was an improvement in scleritis, conjunctivitis, and retinal vasculitis; however, the white retinal lesion progressed to retinal atrophy. Concurrently, a decrease in the number of vitreous cells emanating from the area of fountain-like leakage was noted.\u0000 \u0000 \u0000 \u0000 Retinal manifestations of relapsing polychondritis are underrepresented in the literature. This report presents a unique case of relapsing polychondritis with a localized retinal manifestation observed on OCT imaging, thereby broadening our understanding of the potential localized retinal presentations associated with this disease.\u0000","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":"11 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140739493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perfluorocarbon Liquid-Silicone Oil Exchange: The Simplicity and Reliability of the Single Port Technique and a Review of Literature","authors":"Sukhum Silpa-archa, Variya Nganthavee","doi":"10.1097/icb.0000000000001579","DOIUrl":"https://doi.org/10.1097/icb.0000000000001579","url":null,"abstract":"\u0000 \u0000 To report the “Single Port Technique” for perfluorocarbon liquid (PFCL)-silicone oil (SO) exchange for the management of giant retinal tear detachments (GRTD).\u0000 \u0000 \u0000 \u0000 The previously reported techniques of direct PFCL-SO exchange used 2 ports to achieve the influx and outflux of fluid. The term 'Single Port' refers to the use of only one port as the exclusive port for the inflow of SO and the outflow of fluid meniscus and PFCL, performed alternately. This technique is proposed, with illustrated instructions and a surgical video.\u0000 \u0000 \u0000 \u0000 The newly proposed “Single Port Technique” offers a straightforward step using a switch between active aspiration by the vitreous cutter and active silicone oil injection through a single port without the need for assistance. This method has been performed by the authors on 29 patients, including 22 GRTD patients and 7 patients with rhegmatogenous retinal detachment caused by dialysis, and it has demonstrated its simplicity and reliability for use with only standard vitrectomy tools and machine settings.\u0000 \u0000 \u0000 \u0000 The Single Port Technique for PFCL-SO exchange for the management of GRTD and rhegmatogenous retinal detachment caused by dialysis has been tried and tested, and it is a valuable tool that can be easily used by any vitreoretinal surgeon.\u0000","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":"12 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140743968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hermosa A, Vela Ji, Loscos-Giménez I, Verdú A, Rego-Lorca D
{"title":"SPONTANEOUS RESOLUTION OF SUBFOVEAL PERFLUOROCARBON: CASE REPORT AND REVIEW OF THE LITERATURE","authors":"Hermosa A, Vela Ji, Loscos-Giménez I, Verdú A, Rego-Lorca D","doi":"10.1097/icb.0000000000001583","DOIUrl":"https://doi.org/10.1097/icb.0000000000001583","url":null,"abstract":"\u0000 \u0000 To report a case of spontaneous resolution of subfoveal perfluorocarbon liquid (sPFCL). Methods: A 72-year-old male presented with poor vision in the left eye for two months. Ophthalmic examination revealed a visual acuity of counting fingers at 40 cm, pseudophakia, and rhegmatogenous retinal detachment in the left eye. The patient underwent 23G pars plana vitrectomy associated with a scleral buckle and silicone oil. Postoperatively, a retained sPFCL bubble was observed on OCT image. Results: Postoperatively, the sPFCL bubbles disappeared spontaneously by a full-thickness macular hole. Four weeks after surgery, the macular hole was closed, and visual acuity improved with preservation of foveal depression. Conclusion: Because spontaneous resolution rarely occurs, retinal surgeons prefer early evacuation of sPFCL. Herein, we report a new case of spontaneously resolved sPFCL and discuss the mechanisms for its resolution reported in the literature.\u0000","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":"44 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140743601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hazuki Morikawa, Tomoyo Yoshida, Emi Kashizuka, Shion Hayashi, T. Yokoi, Kaoru Tomita, N. Azuma, S. Nishina
{"title":"CHOROIDAL NEOVASCULARIZATION IN A CHILD WITH DOWN SYNDROME","authors":"Hazuki Morikawa, Tomoyo Yoshida, Emi Kashizuka, Shion Hayashi, T. Yokoi, Kaoru Tomita, N. Azuma, S. Nishina","doi":"10.1097/icb.0000000000001541","DOIUrl":"https://doi.org/10.1097/icb.0000000000001541","url":null,"abstract":"To report a case of Down syndrome with myopic choroidal neovascularization (CNV) and the treatment outcome. Case report. Main outcome measures include refractive error, fundus examination, optical coherence tomography (OCT), OCT angiography (OCTA), fluorescein angiography (FA), anti-vascular endothelial growth factor (VEGF) injections. A 12-year-old boy with Down syndrome presented at a regular check-up with decreased visual acuity (VA) with macular degeneration in the left eye. The best-corrected VA was 0.6 in the right eye and 0.1 in the left eye, which decreased from 0.3 1 year ago. The refractive error (spherical equivalent) was -5.25 diopters (D) in the right eye and -8.00 D in the left eye. Detailed examinations were performed under general anesthesia. The fundus examination showed macular degeneration with retinal pigment epithelium (RPE) atrophy, pigmentary changes, and fibrous tissue in the left eye. OCT showed CNV at the macula with edema, and OCTA showed spreading CNV above the RPE at the macula in the left eye. FA showed hyperfluorescence in the early phase and late dye leakage from the CNV. Intravitreal ranibizumab injections were administered twice within 2 months, and he maintained a VA of 0.1 in the left eye. CNV and associated macular degeneration may occur in Down syndrome with high myopia possibly because of the abnormal choroidal structure. In children with Down syndrome, regular fundus examinations with OCT are important for early detection and treatment of CNV.","PeriodicalId":510632,"journal":{"name":"RETINAL Cases & Brief Reports","volume":"163 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139178849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}