Drug Information Journal最新文献_第8页

Auditing clinical research data: objectives, applications and results. 审核临床研究数据:目的、应用和结果。

Drug Information Journal Pub Date : 1983-01-01

R L Justice

引用次数: 0

Drug design and the CAS ONLINE substructure search system. 药物设计与CAS ONLINE子结构检索系统。

Drug Information Journal Pub Date : 1983-01-01 DOI: 10.1177/009286158301700408

F B Winer

{"title":"Drug design and the CAS ONLINE substructure search system.","authors":"F B Winer","doi":"10.1177/009286158301700408","DOIUrl":"https://doi.org/10.1177/009286158301700408","url":null,"abstract":"CAS ONLINE, the chemical substance search and display system available directly from Chemical Abstracts Service, is a new service which is particularly useful in drug design studies. In CAS ONLINE chemists search by structures to identify chemical substances, for example, derivatives or analogs of a drug or its pharmacologically active fragment, which share user-defined features. Search questions are phrased in terms of one or more structure diagrams, each of which can include variable atoms, bonds, or positions of substitution as required by the searcher. CAS ONLINE provides access to the world's largest (more than 6 million substance records) and most current chemical structure information data base. CAS ONLINE is updated weekly with 7,000-10,000 new substance records. Substance information available from searches in CAS ONLINE include structure diagrams, systematic and common names (including trade names) for substances, molecular formulas, and the widely cited CAS Registry Numbers. The searcher may optionally request for each substance bibliographic information for the ten most recent literature references which have been cited in Chemical Abstracts since 1967.","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"17 4","pages":"277-86"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158301700408","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21133960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Quality assurance operations: good clinical practices. 质量保证操作:良好的临床操作规范。

Drug Information Journal Pub Date : 1983-01-01

A W Castellion

引用次数: 0

An Asian perspective on drug and related health care information. 亚洲对药物和相关保健信息的看法。

Drug Information Journal Pub Date : 1983-01-01 DOI: 10.1177/009286158301700406

E W De Maar, N A Kshirsagar, I Darmansjah

{"title":"An Asian perspective on drug and related health care information.","authors":"E W De Maar, N A Kshirsagar, I Darmansjah","doi":"10.1177/009286158301700406","DOIUrl":"https://doi.org/10.1177/009286158301700406","url":null,"abstract":"To ensure that drugs are available in adequate quantity and quality for the health needs of the population and properly used, Asian governments in the past decades have exercised their sovereign rights quite independently and differently. A high number of patients per prescribing physician has consequences for drug information, in regard to both prescribers and consumers needing to self-medicate. To reliably inform patients through physicians, pharmacists, or medical auxiliary personnel is of great importance in the face of an illiteracy problem. Self- medication and illiteracy place emphasis on communication by word of mouth or by pictures. Word of mouth is the most important route, because even with a steady increase in literacy, the increase in transistor radios has been even more pronounced. For specific health information, instructional posters, with emphasis on pictures, have been very effective. Billboards do not allow adequate information disclosure needed for drugs. The opportunity to expand the coverage of consumer drug information, in that labelling for consumers gives additional relevant general health information, seems appropriate.","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"17 4","pages":"263-9"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158301700406","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21131852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Collaboration and work sharing of drug information services in the United Kingdom. 联合王国药物信息服务的协作和工作共享。

Drug Information Journal Pub Date : 1983-01-01 DOI: 10.1177/009286158301700207

H McNulty

引用次数: 3

FDA approval of comparative claims for prescription drugs--the Moxam case. FDA批准处方药的比较索赔——Moxam案例。

Drug Information Journal Pub Date : 1983-01-01 DOI: 10.1177/009286158301700306

D Marcus

引用次数: 0

Selection of scientific periodicals to monitor drug safety information using Excerpta Medica and Japicdoc in the post marketing surveillance of drugs. 在药品上市后监测中，利用《医学摘录》和《Japicdoc》进行药品安全信息监测的科学期刊选择。

Drug Information Journal Pub Date : 1983-01-01 DOI: 10.1177/009286158301700307

T Kitaguchi, T Nojiri, S Suzuki, T Fukita, T Kawana

引用次数: 2

Product selection, bioequivalence, and therapeutic equivalence: the generic drug market. 产品选择、生物等效性和治疗等效性:仿制药市场。

Drug Information Journal Pub Date : 1983-01-01 DOI: 10.1177/009286158301700204

J A Halperin

{"title":"Product selection, bioequivalence, and therapeutic equivalence: the generic drug market.","authors":"J A Halperin","doi":"10.1177/009286158301700204","DOIUrl":"https://doi.org/10.1177/009286158301700204","url":null,"abstract":"Pharmacists are continually faced with drug product selection decisions. When is a generic drug product equivalent to the innovator product and, thus, a suitable candidate for generic substitution? The FDA policy has been that only drug products that are therapeutic equivalents are candidates for product selection decisions. This paper outlines the regulatory and scientific framework for the FDA's policies and requirements for generic drug products. The history and current status of the Drug Efficacy Study Implementation (DESI) project is described. Originally begun in 1966 as a review of about 3,400 drug products, the review in mid-1983 is more than 90% complete, but its impact has already affected more than 7,000 marketed drug products. The therapeutic equivalence policy and the manner in which decisions on therapeutic equivalence are communicated are reviewed. Regulatory policies for the approval of generic drug products are reviewed and specific litigation challenging the rights of generic drug manufacturers to produce generic \"look-alikes\" and challenging the FDA's policy that a generic drug product is a new drug requiring an approved New Drug Application for marketing is discussed. The conclusion reached is that the evaluation of regulatory requirements and science is leading to a point where all generic drug products will be known to be safe, effective and therapeutically equivalent, and pharmacists can be optimistic about the quality of products in the generic drug market.","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"17 2","pages":"73-6"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158301700204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21132974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Development of a computerized drug interaction database (MEDICOM) for use in a patient specific environment. 开发用于患者特定环境的计算机化药物相互作用数据库(MEDICOM)。

Drug Information Journal Pub Date : 1983-01-01 DOI: 10.1177/009286158301700309

A F Shinn, R P Shrewsbury, K W Anderson

{"title":"Development of a computerized drug interaction database (MEDICOM) for use in a patient specific environment.","authors":"A F Shinn, R P Shrewsbury, K W Anderson","doi":"10.1177/009286158301700309","DOIUrl":"https://doi.org/10.1177/009286158301700309","url":null,"abstract":"Drug Interactions are a clearly defined problem that we as health professionals must deal with on a day-by-day basis. It is by far the area of health care that demands more attention today and tomorrow than was possible in the past. The amount of reference sources and text material of drug interactions is growing at such a rate that it is almost impossible to recall essential information in a reasonable time frame. If the practitioner is to continue with an uninterrupted work flow and still maintain the best possible service for the patient, an immediate and accurate method is needed in the hands of the user ... a computerized drug interaction database. The community health care standards would be ultimately raised to a level never before attainable and efficiency would continue with full utilization of professional practice. Combine then, drug interaction data with ancillary benefits such as cost containment, third party accounting, inventory control, and a multitude of other operational functions into a computerized database and the end product results in an enhanced, controlled, professional operation.","PeriodicalId":51023,"journal":{"name":"Drug Information Journal","volume":"17 3","pages":"205-10"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/009286158301700309","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21131850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

The role of the innovation-based pharmaceutical industry in international drug information communication. 创新医药产业在国际药品信息交流中的作用。

Drug Information Journal Pub Date : 1983-01-01 DOI: 10.1177/009286158301700407

L C Hoff

引用次数: 3