Catalysis Surveys from Asia最新文献

{"title":"Green Synthesis of Iron Oxide-Based Superacid Catalysts Modified with Graphene Oxide for Efficient Esterification Reactions","authors":"Abeer A. Elssawy,&nbsp;Mohsen M. T. El-Tahawy,&nbsp;Hussein A. Khalaf","doi":"10.1007/s10563-024-09443-0","DOIUrl":"10.1007/s10563-024-09443-0","url":null,"abstract":"<div><p>Iron oxide-based superacid catalysts were successfully prepared using impregnation method. Graphene oxide was prepared from sugarcane bagasse, the biowaste of sugar factories, modified Hummer’s method. Fe₂O₃ prepared by precipitation method followed by impregnation with ammonium persulfate and doped with graphene oxide. These catalysts were applied to the esterification of oleic acid with methanol at various conditions such as temperature, reaction time, and catalyst dosage. The highest yield of 96% was achieved using 0.2 g of S₂/Fe₂O₃ at 100 °C for 3 h, indicating a high density of Brønsted and Lewis acid sites on its surface. Catalyst characterization (XRD, SEM, FTIR, N₂ adsorption-desorption analysis, and TGA) confirmed good nanoparticle crystallinity, effective intercalation of metal oxides with persulfate and graphene oxide, and a predominantly mesoporous structure. Sulfation with ammonium persulfate significantly enhanced the acidity of iron oxide, while the addition of graphene oxide provided a moderate acidity increase. This increase in acidity positively impacted the conversion rate of oleic acid with methanol. All three catalysts (GF, SF, GSF) demonstrated strong reusability for oleic acid esterification, maintaining conversion efficiency above 50% after six cycles, indicating economic feasibility with minimal efficiency loss. Overall, this solid superacid catalyst presents a promising green pathway for ester synthesis and biodiesel production.</p></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 2","pages":"111 - 126"},"PeriodicalIF":2.1,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catalytic Production of Glycerol Carbonate from Glycerol Using Sunflower Stalk-Derived Biochars: Fabrication, Characterization, and Performance Evaluation","authors":"Emine Sert,&nbsp;Esra Yılmaz Mertsoy,&nbsp;Murat Sert","doi":"10.1007/s10563-024-09444-z","DOIUrl":"10.1007/s10563-024-09444-z","url":null,"abstract":"<div><p>This study investigates the fabrication, characterization, and catalytic performance of innovative biochars derived from sunflower stalk cellulose, emphasizing their potential as sustainable catalysts in green chemistry applications. Biochars were produced via pyrolysis at 450, 550, and 650 °C, yielding samples labeled SSB1, SSB2, and SSB3, respectively. The production of glycerol carbonate through the transesterification of glycerol and dimethyl carbonate (DMC) was selected as a model reaction to evaluate the catalytic efficacy of these biochars. This approach aligns with the principles of green chemistry, addressing the effective utilization of biomass waste and excess glycerol while contributing to a circular economy. Characterization using FTIR, XRD, TGA, N₂ adsorption, and SEM-EDX analyses revealed significant effects of pyrolysis temperature on the physicochemical properties of the biochars, including yield, pH, surface area, and mineral content. Higher pyrolysis temperatures led to increased porosity, surface area, and mineral content, which enhanced catalytic performance. Under optimized conditions, the catalytic activity of SSB1, SSB2, and SSB3 was evaluated at a reaction temperature of 110 °C, a catalyst loading of 5 wt%, a reaction period of 20 min, and a DMC-to-glycerol molar ratio of 5:1. Among the biochars, SSB3 demonstrated the highest catalytic activity, achieving a glycerol conversion rate of 65.3% and glycerol carbonate selectivity of 53.4%. By linking the structure-performance relationship, this paper highlights the innovation and logic of utilizing biochars as effective catalysts in heterogeneous processes. The findings demonstrate the potential of biochars derived from sunflower stalk residues as sustainable alternatives to conventional catalysts, offering valuable insights into the development of functional materials for environmentally friendly chemical processes.</p></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 2","pages":"127 - 138"},"PeriodicalIF":2.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tungstic Acid-Functionalized Natural Zeolite as a Solid Acid Catalyst for Levulinic Acid Esterification","authors":"Latifah Hauli,&nbsp; Febriana,&nbsp;Isalmi Aziz,&nbsp;Muhammad Safaat,&nbsp;Hendris Hendarsyah Kurniawan,&nbsp;Resta Adelia,&nbsp;Mohammad Jihad Madiabu,&nbsp; Muflikhah,&nbsp;Dicky Annas,&nbsp;Silvester Tursiloadi","doi":"10.1007/s10563-024-09442-1","DOIUrl":"10.1007/s10563-024-09442-1","url":null,"abstract":"<div><p>The investigation of the process of converting levulinic acid (LA) into ethyl levulinate (EL) using tungstic acid (TA)-functionalized activated natural zeolite (AZ) was systematically conducted. The aims of this work were to synthesize and characterize the activated zeolite modified by tungstic acid (TA-AZ) and also evaluate its performance in LA esterification. We employed the wet impregnation approach and ultrasonication-assisted method to produce TA-AZ catalyst with different concentrations of TA (15, 20, and 25 wt%). Fourier transform infrared (FTIR), ammonia-temperature programmed desorption (NH₃-TPD), X-ray diffraction (XRD), scanning electron microscope with an energy dispersive X-ray spectrometer (SEM-EDX), transmission electron microscope (TEM), and surface area analyzer (SAA) were among the analytical methods used to investigate the chemical and physical characteristics of AZ and TA-AZ catalysts. The liquid yields from LA esterification were analyzed by GC-FID. The findings indicated that the 25TA-AZ catalyst exhibited the highest acidity, reaching 3.65 mmol/g. The presence of TA in AZ resulted in an enhancement of LA conversion and an increase in EL yield. The LA esterification process, employing a 25TA-AZ catalyst with a reaction temperature of 150 °C and a weight% of 0.5 wt%, produced 91.72% for LA conversion and 82.65% for EL yield.</p></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 1","pages":"97 - 109"},"PeriodicalIF":2.1,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143362081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron Nanoparticle-Catalyzed Enantioselective Electro-Organic Carboxylation of Styrenes with CO2 Using Graphene Oxide Modified with PyrCO-cyclo@Fe in the Presence of Deep Eutectic Electrolyte and Solvent","authors":"Amer Alhaj Zen,&nbsp;Majid S. Jabir,&nbsp;Zaman Abdalhussein Ibadi Alaridhee,&nbsp;Rafid Kamal Jameel,&nbsp;Morug Salih Mahdi,&nbsp;Aseel Salah Mansoor,&nbsp;Usama Kadem Radi,&nbsp;Ameer Hassan Idan,&nbsp;Hala Bahair,&nbsp;Elyor Berdimurodov,&nbsp;Hasan Majdi,&nbsp;Abdulrahman A. Almehizia","doi":"10.1007/s10563-024-09439-w","DOIUrl":"10.1007/s10563-024-09439-w","url":null,"abstract":"<div><p>This study explores the use of graphene oxide (GO) modified with PyrCO-cyclo@Fe as an efficient and selective catalyst. The modification of GO with PyrCO-cyclo@Fe provides a robust platform for the synthesis of (S)-2-phenylpropanoic acid derivatives <b>4(a–l)</b>, facilitated by the presence of choline chloride ethylene glycol (ChCl/EGC) as the electrolyte in good to excellent yields (89–97%). The experimental results demonstrate that this catalytic system not only enhances the enantioselectivity of the carboxylation process but also improves the overall yield and efficiency. This method presents a promising approach for the production of valuable enantioenriched carboxylic acids, contributing to the development of green and sustainable catalytic processes in organic synthesis. The synthesized GO-PyrCO-cyclo@Fe electrode was examined utilizing various analytical methods, including FT-IR, CV, SEM, EDS, BET, TGA, and XPS The synthesized (S)-2-phenylpropanoic acid derivatives <b>4(a–l)</b> were identified and characterized through melting point determination, FT-IR, ¹HNMR, and CHN analyses.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 1","pages":"37 - 57"},"PeriodicalIF":2.1,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143362156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CdS/MoS2 Heterojunctions: Facile Synthesis and Photocatalytic Reduction of the Toxic Cr(VI) to Cr(III) Micronutrient","authors":"Haseeb Ullah,&nbsp;Rizwana Ghazi,&nbsp;Shili Gai,&nbsp;Abeer A. AlObaid,&nbsp;Nabil Al-Zaqri,&nbsp;Ziaur Rehman","doi":"10.1007/s10563-024-09440-3","DOIUrl":"10.1007/s10563-024-09440-3","url":null,"abstract":"<div><p>Among the aquatic pollutant remediation reactions, the reduction of toxic Cr(VI) to a benign Cr(III) is of significant interest. Among the avrious remediation methods, photocatalysis is considered optimal due to its efficiency and eco-friendly nature. Therefore, the development of highly active, visible-light-responsive, and noble-metal-free photocatalysts for the elimination of toxic heavy metal ions from wastewater is highly desirable. In this study, a facile two-step method, comprising solvothermal and hydrothermal, was used to synthesize visible-light-responsive CdS/MoS₂ heterojunctions (CM-HJs). Extensive structural characterization was performed to assess the crystal structure (XRD and XPS), morphology (SEM and BET), and optical (UV-Vis) properties of the as-synthesized photocatalysts. Aquatic Cr(VI) photoreduction was conducted on these photocatalysts under visible light irradiation. The results revealed the high photocatalytic activity and photostability of CM-HJs for Cr(VI) reduction compared to the bare CdS. Among the heterojunctions, CM-10 (10 wt % MoS₂) exhibted the highest acvtivty, reducing 99.04% of Cr(VI) within 60 min. The enhanced photocatalytic activity can be attributed to its high light harvesting capability and efficient separation and transportation of the produced electron-hole pairs due to the intimate contact interfaces and matching band potentials of CdS with MoS₂. Based on the literature and experimental evidence, a photocatalytic mechanism for the photoreduction of Cr(VI) is discussed in detail. The effect of different parameters; like the amount of photocatalyst, amount of Cr(VI), and pH were also evaluated. Like other good photocatalysts, CM-10 owes good photostability and recyclability.</p></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 1","pages":"58 - 70"},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143361820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catalytic Activity of MnWO4@g-C3N4 and CuWO4@g-C3N4 Nano-Composites for Green Fuel Production","authors":"Muhammad Saeed,&nbsp;Amir Waseem,&nbsp;Azeem Intisar","doi":"10.1007/s10563-024-09437-y","DOIUrl":"10.1007/s10563-024-09437-y","url":null,"abstract":"<div><p>The present study successfully synthesized MnWO₄@g-C₃N₄ and CuWO₄@g-C₃N₄ nanocomposites which demonstrated high efficiency and recoverability as a robust catalyst for ODS of model (DBT) and real fuel oil (kerosene and diesel). The manufactured composites were thoroughly characterized using XRD, TGA, FTIR, SEM and EDX confirming its physicochemical properties. The SEM results revealed that MnWO₄ and CuWO₄nanoparticles were well organized on the exterior of g-C₃N₄ forming interesting spherical particle morphology. Under optimized conditions, the nanocomposites MnWO₄@g-C₃N₄ and CuWO₄@g-C₃N₄ exhibited an impressive 98 and 98.5% removal of DBT, respectively from the model fuel (100 mg/L) within 180 min at a temperature of 45 °C using 1 mL of oxidant and 0.1 g of catalyst amount. Furthermore, the catalytic activity of composites was investigated for real fuel desulfurization and promising results were achieved. Moreover, the fuel properties were in accordance with ASTM specifications. The study found that the desulfurization reaction followed the pseudo 1st order kinetic models and the negative ∆G indicated a spontaneous method. The nanocomposites exhibited promising reusability as it could be used up to five times without significantly reducing their ability to desulfurize fuel oil. The study highlights its potential for practical applications in reducing sulfur content in fuel oils contributing to cleaner and environment friendly energy production and utilization.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 1","pages":"11 - 25"},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143361821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Applications of Zinc Oxide Nanorods, Copper-Doped Zinc Oxide Nanorods, Nickel Hydroxide/Zinc Oxide Nanorods, Iron (III) Oxide/Zinc Oxide Nanorods and Zinc Oxide/Graphene Oxide Nanorods for Batch Adsorption, Fixed-Bed Column Study, and Degradation of Cationic Dye (Blue Tur-XGB B-3) from Wastewater","authors":"Humna Munawwar,&nbsp;Ruba Munir,&nbsp;Amna Muneer,&nbsp;Fatima Zaheer,&nbsp;Muhammad Zeeshan Bashir,&nbsp;Murtaza Sayed,&nbsp;Muhammad Zahid,&nbsp;Raziya Nadeem,&nbsp;Nazish Jahan,&nbsp;Saima Noreen","doi":"10.1007/s10563-024-09441-2","DOIUrl":"10.1007/s10563-024-09441-2","url":null,"abstract":"<div><p>Industrial dyes from commercial sector are one of the major contributors to the environmental contamination. This research work mainly focuses on the elimination of synthetic cationic dye (Blue Tur-XGB B-3) through column and batch studies followed adsorption phenomenon. Various methods were employed to prepare the Zinc Oxide nanorods (ZnO) and different metal doped Zinc Oxide nanorods (Cu/ZnO, Ni(OH)₂/ZnO, α-Fe₂O₃/ZnO, GO/ZnO) as adsorbents. The synthesize nanorods were characterized by using FTIR analysis and SEM to confirmed the morphology and functional group of the prepared nano adsorbents. Followed the adsorption procedure the optimum pH for the cationic dye (Blue Tur-XGB B-3) was detected in the basic range which was 9 for ZnO (29.54 mg g⁻¹), 10 for Cu/ZnO (37.96 mg g⁻¹), 10 for Ni(OH)₂/ZnO (35.76 mg g⁻¹), 9 for α-Fe₂O₃/ZnO (31.88 mg g⁻¹), 9 for GO/ZnO (33.05 mg g⁻¹). The optimum dosage for all the prepared adsorbents were detected 0.05 g/50 mL and showed best adsorption capacity at temperature of 30 °C and 60 min of contact time. The initial concentration of dye was observed at the range of 125–150 mg L⁻¹ and best adsorption capacity was achieved at 100 mg L⁻¹ by all adsorbents. Photocatalysis experiment for determination of effect indicated the highest degradation efficiency of 90.49% for Cu doped ZnO NRs, 87.90% for Ni(OH)₂/ZnO NRs, 79.16% for α-Fe₂O₃/ZnO, 70% for ZnO/GONRs and 60.53% for ZnO NRs at 308 K for catalytic degradation of cationic dye (Blue Tur-XGB B-3). Adsorption followed both Langmuir and Freundlich isotherms for all adsorbents. Kinetic adsorption data supported Pseudo 1st and pseudo 2nd order kinetics while thermodynamics analysis indicated spontaneous and exothermic nature. Effect of surfactants, electrolytes, heavy metals and desorption were also evaluated. For column study, optimum bed height (3 cm), optimum flow rate (1.8 mL min⁻¹) and optimum inlet dye concentration (70 mg L⁻¹) were also observed for maximum adsorption of cationic dye (Blue Tur-XGB B-3). With the help of ZnO, the degradation of Blue Tur-XGB B-3 dye was also investigated. These methods are very cost effective, ecofriendly and easy to manufacture. The recycling results show that the ZnO nanostructures displayed good stability and long-term durability.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 1","pages":"71 - 96"},"PeriodicalIF":2.1,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143362239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of SBA-15 Morphology in the Catalytic Performance of Pt/Ce-SBA-15 Catalyst for NOx Reduction","authors":"Shyam Sunder Rao,&nbsp;Anjali Bharti,&nbsp;Vivek Kumar Patel,&nbsp;Sweta Sharma","doi":"10.1007/s10563-024-09438-x","DOIUrl":"10.1007/s10563-024-09438-x","url":null,"abstract":"<div><p>This research used hydrothermal technique to synthesize three different morphologies of SBA-15 supports, such as rod, hexagonal prism, and spherical. Afterward, it impregnated Pt/Ce metal on the SBA-15 supports via wet-impregnation methods and investigated their NO reduction activity using the H₂-SCR technique in the temperature range of 50–450℃. The catalysts were characterized by Brunauer-Emmett-Teller (BET), X-Ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Scanning electron microscopy, energy dispersive X-ray spectroscopy <b>(</b>SEM-EDS), Transmission electron microscopy (TEM), and Raman spectroscopy. Among the catalysts, Pt/Ce-SBA-15-rod exhibited the best performance with NO conversion of 52.23% and N₂ selectivity of more than 83.25% at 150℃. The Pt/Ce-SBA-15-rod catalysts’ activation energy (21.188 kJ-mol^− 1) was the lowest of all the catalysts. The catalysts with the highest NO conversion have the highest BET properties, surface oxygen (30.33%), Ce³⁺ (40.23%), Pt (0) (70.45%), and oxygen storage capacity.</p></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 1","pages":"26 - 36"},"PeriodicalIF":2.1,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143361866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct CO2 Methylation to Value-Added Aromatics Through Tandem Catalysis","authors":"Yong Yang,&nbsp;Yukun Li,&nbsp;Qiong Qin,&nbsp;Dongliang Wang,&nbsp;Huairong Zhou,&nbsp;Dongqiang Zhang","doi":"10.1007/s10563-024-09436-z","DOIUrl":"10.1007/s10563-024-09436-z","url":null,"abstract":"<div><p>The direct CO₂ methylation, coupling CO₂ hydrogenation with benzene ring methylation, provides a promising strategy to synthesize value-added aromatics using green hydrogen and CO₂ as C1 source. The tandem reaction promotes the conversion of CO₂ due to the consumption of in situ formed methoxy or methanol over the tandem catalyst of metal oxide and acid zeolite. This review aims to present the thermodynamics advantage and mechanistic insights of direct CO₂ methylation process. In practice, catalytic conversion and selectivity for typical tandem catalysts are still far below the thermodynamic equilibrium. The detail roles and proximity effects for metal oxide and acid zeolite are covered in order to give directions to the catalyst design and reaction condition optimization, which has been proposed to overcome the kinetic limitation for the direct CO₂ methylation development in future.</p></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"29 1","pages":"1 - 10"},"PeriodicalIF":2.1,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143361742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Montmorillonite Catalysed Ultrasonic Assisted one-pot Synthesis of Novel 2,3-dihydroisoxazolo[5,4-d] pyrimidin-4(7H)-ones as Potential Anticancer Agents","authors":"Samika Anand,&nbsp;Sunaja Devi K. R.,&nbsp;Santhosh Govindaraju,&nbsp;Sumaiya Tabassum","doi":"10.1007/s10563-024-09435-0","DOIUrl":"10.1007/s10563-024-09435-0","url":null,"abstract":"<div><p>The development of novel compounds with potential anticancer activity is imperative for combating the challenges posed by cancer. In this study, a modified montmorillonite based catalyst is employed for the synthesis of 2,3-dihydroisoxazolo[5,4-<i>d</i>] pyrimidin-4(7 H)-ones, which are promising candidates for anticancer agents. Montmorillonite is modified using mixed metal oxides, typically Al₂O₃ and CeO₂, by a facile approach followed by standard spectroscopic and electron microscopic characterizations. It is then employed for the one-pot synthesis of a series of 2,3-dihydroisoxazolo[5,4-<i>d</i>] pyrimidin-4(7 H)-ones. The synthesis protocol, mediated by ultrasound, is simple, efficient, and environment friendly. The mixed metal oxide pillared montmorillonite catalyst exhibits high catalytic activity and selectivity, facilitating the formation of the desired compounds in good to excellent yields. The synthesized compounds are characterized using various spectroscopic techniques such as ¹H NMR, ¹³C NMR and mass spectrometry. Furthermore, the anticancer activity of the synthesized compounds is evaluated against a series of cancer cell lines, revealing promising cytotoxic effects. The findings of this study highlight the potential of novel 2,3-dihydroisoxazolo[5,4-<i>d</i>] pyrimidin-4(7 H)-ones as promising anticancer agent, warranting further investigation for their therapeutic potential.</p></div>","PeriodicalId":509,"journal":{"name":"Catalysis Surveys from Asia","volume":"28 4","pages":"435 - 451"},"PeriodicalIF":2.1,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142204696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}