Cirugia Y Cirujanos最新文献_第5页

Peritoneal carcinomatosis index and overall survival in patients taken to cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy. 行细胞减缩手术加腹腔热化疗的腹膜癌指数和总生存率。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000272

Horacio N López-Basave, Flavia Morales-Vázquez, Ángel Herrera-Gómez, Gerardo Miranda-Devora, Alejandro E Padilla-Rosciano, Carolina Castillo-Morales, César A Paleta-Torres, Ezequiel Vázquez-Cortes

{"title":"Peritoneal carcinomatosis index and overall survival in patients taken to cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy.","authors":"Horacio N López-Basave, Flavia Morales-Vázquez, Ángel Herrera-Gómez, Gerardo Miranda-Devora, Alejandro E Padilla-Rosciano, Carolina Castillo-Morales, César A Paleta-Torres, Ezequiel Vázquez-Cortes","doi":"10.24875/CIRU.22000272","DOIUrl":"https://doi.org/10.24875/CIRU.22000272","url":null,"abstract":"Background: The peritoneal carcinomatosis (PC) secondary to gastrointestinal or gynecological cancer has increased its incidence. It has a worse prognosis compared to other sites of metastasis. The peritoneal carcinomatosis index (PCI) establishes overall survival in patients with gastrointestinal or gynecological tumors and carcinomatosis.Objective: To evaluate the relationship of PCI to overall survival (OS) and recurrence-free survival (RFS) in patients treated with cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC).Method: A descriptive, retrolective study of 80 charts of patients with CP was conducted. We included patients with colon, ovarian, appendicular, pseudomyxoma and gastric tumors with CP treated with CRS plus HIPEC. The OS and RFS were determined according to the type of adenocarcinoma and the degree of differentiation. The OS and RFS were determined in months in patients with PCI > 15 PCI as well as in patients with PCI < 15 considering the tumor of origin.Results: Patients with ovarian tumors and pseudomyxoma with PCI < 15 presented OS > 70 months, compared to patients with gastric tumors (4 months).Conclusions: The PCI and histology are predictors of OS. Patients with ovarian tumors and PCI < 15 have higher OS, similar to pseudomyxomas. RFS was also higher in patients with PCI < 15.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"195-199"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9477334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of laser hemorrhoidoplasty in the treatment of hemorrhoidal disease. 激光痔疮成形术治疗痔疮病的疗效观察。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000287

Ayberk Dursun, Gizem Kilinc Tuncer, Korhan Tuncer, Cem Karaali, Gürsoy Erdoğan, Mustafa Emiroglu

{"title":"Effectiveness of laser hemorrhoidoplasty in the treatment of hemorrhoidal disease.","authors":"Ayberk Dursun, Gizem Kilinc Tuncer, Korhan Tuncer, Cem Karaali, Gürsoy Erdoğan, Mustafa Emiroglu","doi":"10.24875/CIRU.22000287","DOIUrl":"https://doi.org/10.24875/CIRU.22000287","url":null,"abstract":"Introduction: Minimally invasive techniques still continue to maintain their popularity in hemorrhoidal disease. In this study, we aimed to present the symptomatic recovery and recurrence rates, post-operative pain levels, and complication rates of patients treated with the laser hemorrhoidoplasty (LHP) method in our clinic.Methods: The data of patients who underwent LHP due to Grades 2, 3, and 4 internal hemorrhoidal disease in our clinic were reviewed retrospectively. The patients enrolled in the study were followed for at least 6 months (6 months, 1 year, and 2 years) and their results were analyzed.Results: A total of 103 patients were included in the study. Seventy-five (72.8%) of them were male and the mean age was 41.6 ± 13.6 years. The mean operation time was 17.9 ± 5.2 min and minor complications developed in 3 (2.9%) patients postoperatively. Mean time to return to normal daily life was 2.17 (1-11) days. Recurrence developed in 16 (17.6%) patients with Grades 2 and 3 disease and in 6 (50%) of 12 patients with Grade 4 disease (p = 0.019).Conclusion: LHP is a popular procedure which is effective in selected patient groups with acceptable recurrence rates.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"179-185"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9477335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increased body fat, physical inactivity, and hypertension are associated with poor quality of life in patients with type 2 diabetes. 体脂增加、缺乏运动和高血压与2型糖尿病患者的生活质量差有关。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.21000441

Lubia Velázquez-López, David Alva-Santana, Adriana Ocaña-Patiño, Jorge Escobedo de la Peña, M Victoria Goycochea-Robles

{"title":"Increased body fat, physical inactivity, and hypertension are associated with poor quality of life in patients with type 2 diabetes.","authors":"Lubia Velázquez-López, David Alva-Santana, Adriana Ocaña-Patiño, Jorge Escobedo de la Peña, M Victoria Goycochea-Robles","doi":"10.24875/CIRU.21000441","DOIUrl":"https://doi.org/10.24875/CIRU.21000441","url":null,"abstract":"Background: Diabetes is a significant health problem that affects quality of life in the medium and long term.Objective: To identify the association between quality of life with comorbidity, metabolic control, and lifestyle in patients with type 2 diabetes.Method: A cross-sectional study was performed in 392 patients. Glycosylated hemoglobin, fasting glucose, lipid profile, blood pressure, weight, waist circumference and body composition were measured. Diabetic neuropathy, renal disease, visual health, diet and physical exercise were measured. Health-related quality of life (HRQoL) was measured with the 36-item Short Form survey (SF-36).Results: The mean age was 54.6 years, 68 % were women, median years of diabetes diagnosis was 7 years. Eighty percent had a good HRQoL (SF-36 ≥ 50). The dimension with the highest score was physical function (81.0), and vitality the lowest (46.5). Body fat was associated with more impairments in the SF-36 dimensions (p < 0.05). Factors associated with worse HRQOL are physical inactivity (odds ratio [OR]: 2.7; 95% confidence interval [95%CI]: 1.10-6.62; p = 0.009), arterial hypertension (OR: 1.78; 95% CI: 1.05-3.02; p = 0.032) and being female (OR: 2.7; 95% CI: 1.45-5.27; p = 0.002).Conclusions: Poor quality of life is associated with higher fat percentage, physical inactivity and hypertension in patients with type 2 diabetes.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"171-178"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9775247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The beneficial effects of the transanastomotic feeding tube in the management of congenital duodenal obstruction: a meta-analysis. 经吻合口饲管治疗先天性十二指肠梗阻的有益效果:一项荟萃分析。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000505

Serkan Arslan, Mustafa Azizoğlu

{"title":"The beneficial effects of the transanastomotic feeding tube in the management of congenital duodenal obstruction: a meta-analysis.","authors":"Serkan Arslan, Mustafa Azizoğlu","doi":"10.24875/CIRU.22000505","DOIUrl":"https://doi.org/10.24875/CIRU.22000505","url":null,"abstract":"Objective: We aimed to assess the evidence on the efficacy and safety of transanastomotic feeding tubes (TAFTs) in neonates with congenital duodenal obstruction (CDO), we conducted a systematic review.Material and methods: Using the databases EMBASE, PubMed, and Cochrane, we carried out a thorough literature search up to 2022. Studies comparing TAFT + and TAFT - for CDO were included. We applied a random effect model.Results: 505 CDO patients who met the inclusion criteria were selected. The TAFT + group had a shorter time to reach full feeds (weighted mean difference [WMD]: -6.63, 95% confidence interval [CI]: -8.83 - -4.43; p < 0.001) and had significantly less central venous catheter (CVC) insertion (I2 = 85%) (RR: 0.43, 95% CI: 0.19-1.00; p < 0.05). Fewer patients in the TAFT + group received parenteral nutrition (PN) (I2 = 78%) (RR: 0.43, 95% CI: 0.20-0.95; p < 0.05). There was no statistically significant difference in terms of the development of sepsis (I2 = 37%) (risk ratio [RR]: 1.35, 95% CI: 0.52-3.46; p > 0.05). No statistically significant difference was observed in terms of length of stay (I2 = 82%) (WMD: 2.22, 95% CI: -7.59-12.03; p > 0.05) and mortality (I2 = 0%) (RR: 0.55, 95% CI: 0.07-4.34; p > 0.05).Conclusions: The use of the transanastomotic tube resulted in early initiation of full feeding, less CVC insertion, and less need for PN.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 3","pages":"326-333"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9806645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pielonefritis xantogranulomatosa: un reto actual para la laparoscopia. 黄色肉芽肿性肾盂肾炎：当前腹腔镜面临的挑战。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000080

Jesús E Rosas-Nava, Eduardo Jiménez-Cisneros, Gustavo A Durán-Hernández, Roberto A García-Carrillo, Juan E Sánchez-Núñez, Eduardo A González-Bonilla, Miguel Maldonado-Ávila, Mario Tellez-Sánchez, Jorge Jaspersen-Gastélum, Víctor E Corona-Montes

{"title":"Pielonefritis xantogranulomatosa: un reto actual para la laparoscopia.","authors":"Jesús E Rosas-Nava, Eduardo Jiménez-Cisneros, Gustavo A Durán-Hernández, Roberto A García-Carrillo, Juan E Sánchez-Núñez, Eduardo A González-Bonilla, Miguel Maldonado-Ávila, Mario Tellez-Sánchez, Jorge Jaspersen-Gastélum, Víctor E Corona-Montes","doi":"10.24875/CIRU.22000080","DOIUrl":"https://doi.org/10.24875/CIRU.22000080","url":null,"abstract":"Objective: To present the results of our case series on laparoscopic nephrectomy in xanthogranulomatous pyelonephritis (XGP).Methods: A retrospective study was conducted that included 143 patients treated with laparoscopic nephrectomy for non-functioning kidney, of whom 15 had XGP, within the time frame of 2011 to 2019. The demographic and clinical data were collected, along with the intraoperative results, complications, and days of hospital stay.Results: Transperitoneal laparoscopic nephrectomy was successfully performed on 15 patients with XGP, with no need for conversion. Mean intraoperative time was 124.4 minutes (range 70-240) and intraoperative blood loss was 148.5 ml (range 30-550), with no blood transfusion required. No intraoperative complications occurred but there was one postoperative complication (6.6%), classified as Clavien-Dindo I (surgical wound infection). Mean hospital stay was 2.85 days (range 2-7).Conclusions: Nephrectomy is the definitive management for XGP, and the laparoscopic approach should be considered a treatment modality, despite the fact that the pathology involves a severe chronic inflammatory process. Its benefits are reduced surgery duration, less blood loss, a lower complication rate, and fewer days of hospital stay, when performed by a skilled and experienced surgeon.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 3","pages":"339-343"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9819520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exactitud diagnóstica en el cáncer de esófago localizado. Estudio observacional retrospectivo. 局部食道癌的诊断准确性。回顾性观察性研究。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.21000722

Ainhoa Andrés-Imaz, Laura Martí-Gelonch, Emma Eizaguirre-Letamendia, José I Asensio-Gallego, José M Enríquez-Navascués

{"title":"Exactitud diagnóstica en el cáncer de esófago localizado. Estudio observacional retrospectivo.","authors":"Ainhoa Andrés-Imaz, Laura Martí-Gelonch, Emma Eizaguirre-Letamendia, José I Asensio-Gallego, José M Enríquez-Navascués","doi":"10.24875/CIRU.21000722","DOIUrl":"https://doi.org/10.24875/CIRU.21000722","url":null,"abstract":"Objective: To assess the accuracy of the diagnostic tests for a correct clinical tumor staging in localized esophageal cancer (EC).Method: Retrospective observational study of patients who underwent esophagectomy for cancer in a referral hospital between January 2003 and September 2019. Those patients who received neoadjuvant treatment were excluded in order to avoid bias from downstaging effects. The preoperative stage was compared with the pathological stage of the surgical specimen. Computed tomography (CT) , endoscopic ultrasound (EUS) and positron emission tomography (PET) were evaluated. The pT stage was correlated with the tumor length described in the esophagram (EG).Results: Among the 63 patients included, the clinical staging was correct in 16 (global accuracy 25.4%), it was overstaged in 21 (33.2%) and understaged in 26 (41.3%). For cT staging, the accuracy of EUS was higher than that of CT (46.6% and 34.9%, respectively), specially for early stages. EG tumor length correlated with pT stage (p < 0.05). For cN staging, PET had the highest sensitivity (50.0%) and negative predictive value (75.0%).Conclusions: Despite the multiple diagnostic tools used, the global accuracy of clinical staging in localized EC is still a challenge. The lack of a test that stands out significantly from the others reinforces the need to use them in a complementary way.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 1","pages":"42-49"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10732238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of homeodomain interacting protein kinase 2 polymorphisms rs2058265, rs6464214, and rs7456421 in patients with kidney stone. 肾结石患者同位结构域相互作用蛋白激酶2多态性rs2058265、rs6464214和rs7456421的测定

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000472

Cavit Ceylan, Omer Gokhan-Doluoglu, Sedat Taştemur, Ibrahim Keleş, Gulay Ceylan, Ahmet Cevdet-Ceylan, Emre Uzun, Eda Tokat

{"title":"Determination of homeodomain interacting protein kinase 2 polymorphisms rs2058265, rs6464214, and rs7456421 in patients with kidney stone.","authors":"Cavit Ceylan, Omer Gokhan-Doluoglu, Sedat Taştemur, Ibrahim Keleş, Gulay Ceylan, Ahmet Cevdet-Ceylan, Emre Uzun, Eda Tokat","doi":"10.24875/CIRU.22000472","DOIUrl":"https://doi.org/10.24875/CIRU.22000472","url":null,"abstract":"Objective: This study aimed to investigate whether homeodomain interacting protein kinase 2 (HIPK2) polymorphism is associated with renal stone formation in a Turkish population.Materials and methods: A total of 129 patients with calcium nephrolithiasis and 67 sex- and age-matched healthy controls were enrolled in the study. Blood samples were collected into EDTA tubes. The DNA of patients was extracted using a QIAsymphony® automated DNA isolation system. The Chi-square test was applied in the comparisons between the patient and control groups in respect of the differences in the genotype and allele frequencies.Results: No statistically significant difference was found between the groups in terms of single nucleotide polymorphism (SNP) incidence in single allele and double alleles in the rs2058265 and rs6464214 regions (p = 0.13 and 0.37, respectively). The SNP incidence in double alleles in nephrolithiasis patients at rs7456421 was statistically significantly lower than in the control group (p = 0.001).Conclusion: Distributions of the genotype and allele of the three polymorphisms (rs2058265, rs6464214, and rs745642 in HIPK2) were not associated with an increased risk of kidney stone in this Turkish population.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 4","pages":"474-478"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10198258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aortoenteric fistulae and their multidisciplinary approach. 主动脉肠瘘及其多学科治疗方法。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.21000702

Haydée Calvo-García, Johnn H Herrera-Kok, Antonio Álvarez-Martínez, Silvia Maqueda-Ara, José M Ortega-Martín, Tomás Elosua-González, María V Diago-Santamaría

引用次数: 0

Intravenous antibiotic therapy after laparoscopic appendectomy in acute complicated appendicitis: the patient clinical response is the key. 腹腔镜阑尾切除术后静脉抗生素治疗急性复杂性阑尾炎：患者的临床反应是关键。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.21000557

Andres Mendoza-Zuchini, Laura C Arce-Polania, Carlos J Pérez-Rivera

{"title":"Intravenous antibiotic therapy after laparoscopic appendectomy in acute complicated appendicitis: the patient clinical response is the key.","authors":"Andres Mendoza-Zuchini, Laura C Arce-Polania, Carlos J Pérez-Rivera","doi":"10.24875/CIRU.21000557","DOIUrl":"10.24875/CIRU.21000557","url":null,"abstract":"Introduction: The guidelines about acute complicated appendicitis (ACA) recommend 3-5 days of postoperative intravenous antibiotics (IVA). Nevertheless, the time selected by the surgeon can vary according to patient clinical response, ACA type, and professional experience. Once an adequate clinical response is obtained, the change from IVA to oral antibiotic (OA) could be realized without the waiting time established with satisfactory results.Objective: Determine if a short course of IVA and/or switch to oral route is safe based on the patient clinical response.Materials and methods: Observational prospective cohort study from a general surgery reference center database since July 2019.Results and conclusion: 48 patients with ACA intraoperative findings were included. Regarding postoperative antibiotic management, only preoperative IVA: 7 (14.58%), IVA 1-3 days: 1 (20.83%), IVA 1-3 days and change to OA: 21 (43.75%), IVA > 3 days: 6 (12.5%), and only OA: 3 (27.08%). The bivariate analysis did not show statistically significant differences in reconsultation (p = 0.81), rehospitalization (p = 0.44), and surgical site infection (p = 0.56) between the antibiotic scheme based on the postoperative clinical response and the traditional one regarding intra-abdominal collection rate, the hospital stays, and hospitalization costs.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 4","pages":"479-485"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10198265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Agreement between incisional and excisional biopsies for hormone receptors and her2 in breast cancer. 乳腺癌中激素受体和her2的切口和切除活检的一致性。

IF 0.5 4区医学

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI: 10.24875/CIRU.22000197

Fernando Candanedo-Gonzalez, Juan C Cordova-Ramón, Jessica Smeke-Smeke, Wilfredo Valenzuela-Gonzalez, Armando Gamboa-Dominguez

{"title":"Agreement between incisional and excisional biopsies for hormone receptors and her2 in breast cancer.","authors":"Fernando Candanedo-Gonzalez, Juan C Cordova-Ramón, Jessica Smeke-Smeke, Wilfredo Valenzuela-Gonzalez, Armando Gamboa-Dominguez","doi":"10.24875/CIRU.22000197","DOIUrl":"https://doi.org/10.24875/CIRU.22000197","url":null,"abstract":"Introduction: Breast cancer is the leading cause of cancer mortality in Mexican women.Objective: The objective of the study was to identify concordances among core needle biopsy (CNB) and excisional biopsies (EB) regarding diagnosis, hormonal receptors (HR), and human epidermal growth factor receptor 2 (Her2).Materials and methods: Core number, demographic data, histological type, and treatment were documented for each sample. Reported HR and Her2 score from both samples were compiled.Results: 70 women with both CNB/EB were included. Median age was 58 (36-87) years; initial diagnosis in CNB were invasive ductal 56 (80%), lobular 10 (14%), and mixed 4 (6%) carcinomas. Diagnostic agreement among CNB and EB was of 97%, k = 0.65. A concordance of 92% (k = 0.75), 75% (k = 0.26), and 67% (k = 0.46) was observed for estrogen receptors, progesterone receptors, and Her2 determinations, and positive predictive values in CNB were 0.96, 0.89, and 0.44, respectively.Conclusion: HR and Her2 concordances using manual-immunohistochemistry (IHC) were found within the range of values obtained using automatized-IHC. When compared to tumor heterogeneity, technical/reading errors contribute more to discordances.","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 4","pages":"451-456"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10199840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0