Advances in Cardiology最新文献_第5页

Diabetes and arterial stiffening. 糖尿病和动脉硬化。

Advances in Cardiology Pub Date : 2007-01-01 DOI: 10.1159/000096745

Nathaniel Winer, James R Sowers

{"title":"Diabetes and arterial stiffening.","authors":"Nathaniel Winer, James R Sowers","doi":"10.1159/000096745","DOIUrl":"https://doi.org/10.1159/000096745","url":null,"abstract":"Type 2 diabetes (DM-2) has become a major global health problem that has been fueled mainly by increasing obesity and aging of the population. Most studies show that arterial stiffening occurs across all age groups in both type 1 diabetes and DM-2, and among those with impaired fasting glucose, impaired glucose tolerance, and the metabolic syndrome. Arterial stiffening in DM-2 results, in part, from the clustering of hyperglycemia, dyslipidemia and hypertension, all of which may promote insulin resistance, oxidative stress, endothelial dysfunction, and the formation of pro-inflammatory cytokines and advanced glycosylation end-products. Likewise, aging may increase arterial stiffening by altering the proportions of elastin and collagen in the aorta. The consequences of arterial stiffening are increased pulse pressure, hypertension, and a greater risk of cardiovascular disease. Treatment strategies to reduce or prevent arterial stiffening include pharmacologic agents that block the renin-angiotensin-aldosterone system, relax vascular smooth muscle, enhance release of nitric oxide from endothelial cells, and break glycosylation end-product cross-links, and fish oil supplementation.","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":"44 ","pages":"245-251"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000096745","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26338365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Atherosclerosis versus arterial stiffness in advanced renal failure. 晚期肾衰竭的动脉粥样硬化与动脉僵硬。

Advances in Cardiology Pub Date : 2007-01-01 DOI: 10.1159/000096730

A Guerin, B Pannier, G London

引用次数: 16

Central pulse pressure and atherosclerotic alterations of coronary arteries. 中心脉压与冠状动脉粥样硬化改变。

Advances in Cardiology Pub Date : 2007-01-01 DOI: 10.1159/000096726

Nicolas Danchin, Jean-Jacques Mourad

{"title":"Central pulse pressure and atherosclerotic alterations of coronary arteries.","authors":"Nicolas Danchin, Jean-Jacques Mourad","doi":"10.1159/000096726","DOIUrl":"https://doi.org/10.1159/000096726","url":null,"abstract":"Central pulse pressure is more likely to reflect the haemodynamic conditions to which the heart and coronary arteries are subjected than is peripheral pulse. We reviewed the data currently available on the correlations between central pulse pressure and both the presence and extent of coronary artery disease, as well as clinical outcomes. Five clinical studies have reported an association between central pulse pressure and the presence of coronary artery disease documented by coronary angiography. Four studies, including three of the previous ones, also found a correlation between central pulse pressure and the extent of coronary artery disease. In one of these studies, however, the correlation was present only in men, whereas no link was found between pulse pressure and coronary artery disease in women. After coronary angioplasty, increased central pulse pressure has been found correlated with the occurrence of restenosis after balloon angioplasty, but not after stent implantation. Finally, the ASCOT-CAFE trial found a positive correlation between pulse pressure and the occurrence of cardiovascular events, confirming the prognostic significance of this parameter.","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":"44 ","pages":"139-149"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000096726","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26338471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Local elasticity imaging of vulnerable atherosclerotic coronary plaques. 易损动脉粥样硬化斑块的局部弹性成像。

Advances in Cardiology Pub Date : 2007-01-01 DOI: 10.1159/000096719

Radj A Baldewsing, Johannes A Schaar, Frits Mastik, Antonius F W van der Steen

{"title":"Local elasticity imaging of vulnerable atherosclerotic coronary plaques.","authors":"Radj A Baldewsing, Johannes A Schaar, Frits Mastik, Antonius F W van der Steen","doi":"10.1159/000096719","DOIUrl":"https://doi.org/10.1159/000096719","url":null,"abstract":"The material composition and morphology of vulnerable atherosclerotic plaque components are considered to be more important determinants of acute coronary syndromes than the degree of stenosis. Rupture of a plaque causes thrombogenic material to contact the blood, resulting in a thrombus. Rupture-prone plaques contain an inflamed thin fibrous cap covering a large soft lipid pool. Mechanically, rupture occurs when plaques cannot withstand the internal stresses induced by the pulsating blood. These stresses concentrate within/around the cap/edge, since the lipid pool cannot bear much stress. During plaque development these stresses further increase when caps become thinner, lipid pools become larger, or the difference in stiffness (modulus) between the cap and the lipid pool increases. Intravascular ultrasound (IVUS) strain elastography/palpography and IVUS modulus elastography are imaging techniques that assess local plaque elasticity (strain and modulus) based on the principle that tissue deformation (strain) by a mechanical stress is a function of its elastic properties (modulus). Combined use of these techniques provides clinicians an all-in-one modality for detecting plaques, assessing their rupture proneness and imaging their elastic material composition. This chapter describes the terminology and pathophysiology of vulnerable plaques and discusses the techniques behind, the methods for and the validations of the elasticity imaging techniques.","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":"44 ","pages":"35-61"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000096719","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26397570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Arterial stiffness and extracellular matrix. 动脉僵硬和细胞外基质。

Advances in Cardiology Pub Date : 2007-01-01 DOI: 10.1159/000096722

Javier Díez

引用次数: 83

Animal models of arterial stiffness. 动脉硬化动物模型。

Advances in Cardiology Pub Date : 2007-01-01 DOI: 10.1159/000096723

Jeffrey Atkinson

引用次数: 3

Homocysteine and large arteries. 同型半胱氨酸和大动脉。

Advances in Cardiology Pub Date : 2007-01-01 DOI: 10.1159/000096748

Coen van Guldener, Coen D A Stehouwer