Advances in Cardiology最新文献

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Alterations in cardiac connexin expression in cardiomyopathies. 心肌病患者心脏连接蛋白表达的改变。
Advances in Cardiology Pub Date : 2006-01-01 DOI: 10.1159/000092572
Nicholas J Severs, Emmanuel Dupont, Neil Thomas, Riyaz Kaba, Stephen Rothery, Revti Jain, Katherine Sharpey, Christopher H Fry
{"title":"Alterations in cardiac connexin expression in cardiomyopathies.","authors":"Nicholas J Severs,&nbsp;Emmanuel Dupont,&nbsp;Neil Thomas,&nbsp;Riyaz Kaba,&nbsp;Stephen Rothery,&nbsp;Revti Jain,&nbsp;Katherine Sharpey,&nbsp;Christopher H Fry","doi":"10.1159/000092572","DOIUrl":"https://doi.org/10.1159/000092572","url":null,"abstract":"<p><p>Gap junctions, assembled from connexins, form the cell-to-cell pathways for propagation of the precisely orchestrated patterns of current flow that govern the synchronized rhythm of the healthy heart. As in most tissues and organs, multiple connexin types are co-expressed in the heart; the connexins Cx43, Cx40 and Cx45 are found in distinctive combinations and relative quantities in different, functionally specialized subsets of cardiomyocytes. Alterations in connexin expression and gap junction organization, now a well-documented feature of human cardiomyopathies, potentially contribute to the pro-arrhythmic substrate. In the diseased ventricle, the most consistently reported quantitative alteration involves heterogeneous reduction in Cx43 expression and disruption of the normal ordered pattern of Cx43 gap junction distribution. Additional studies suggest that upregulation of Cx40 and Cx45 may also feature in the failing ventricle, the former restricted to ischemic cardiomyopathy and localized to the subendocardial region. By correlating data from studies on the human patient with those from animal and cell models, alterations in connexin expression and gap junction organization have emerged as important factors to be considered in understanding the pro-arrhythmic substrate found in human cardiomyopathies.</p>","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":"42 ","pages":"228-242"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000092572","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26376460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 69
Endocardial cushion defects: embryology,anatomy and pathophysiology. 心内膜垫缺陷:胚胎学、解剖学和病理生理学。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079791
Rubin S Cooper
{"title":"Endocardial cushion defects: embryology,anatomy and pathophysiology.","authors":"Rubin S Cooper","doi":"10.1159/000079791","DOIUrl":"https://doi.org/10.1159/000079791","url":null,"abstract":"","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"118-26"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079791","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Strategies for management of postcardiotomy cardiogenic shock following valvular heart surgery. 心脏瓣膜手术后心源性休克的处理策略。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079794
Deon W Vigilance, Mehmet C Oz
{"title":"Strategies for management of postcardiotomy cardiogenic shock following valvular heart surgery.","authors":"Deon W Vigilance,&nbsp;Mehmet C Oz","doi":"10.1159/000079794","DOIUrl":"https://doi.org/10.1159/000079794","url":null,"abstract":"","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"140-9"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079794","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
The Howard Gilman Foundation Lecture. Where have we come from and where are we going? Valve management past, present and future. 霍华德·吉尔曼基金会讲座。我们从哪里来,又往哪里去?阀门管理的过去、现在和未来。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079778
Joseph K Perloff
{"title":"The Howard Gilman Foundation Lecture. Where have we come from and where are we going? Valve management past, present and future.","authors":"Joseph K Perloff","doi":"10.1159/000079778","DOIUrl":"https://doi.org/10.1159/000079778","url":null,"abstract":"<p><p>Leonardo da Vinci's anatomical drawings of quadricuspid, tricuspid, and bicuspid aortic valves underscored the hydraulic superiority of a three leaflet valve with cuspal equality. William Harvey demonstrated that venous valves were designed for unidirectional flow and to prevent reflux from the heart, observations that served as the basis of his immortal de Mortu Cordis. Joseph Rouanet of Paris proposed that heart sounds originated from the closing movements of cardiac valves. The Cardiodynamics of Mitral Insufficiency by Wiggers and Feil was followed three decades later by Paul Wood's An Appreciation of Mitral Stenosis. The Bland/Sweet operation indirectly addressed mitral stenosis by means of a venous shunt. Sir Henry Souttar's early digital repair of mitral stenosis was later reintroduced independently by Harken and Bailey; Doyen, Sellers, and Brock employed surgical valvotomy for pulmonary stenosis, and Bailey employed surgical valvotomy for aortic stenosis. Management of abnormal cardiac valves includes repair (reconstruction), replacement with mechanical or biologic prostheses, and interventional catheterization. The first mechanical valve was inserted extracardiac by Hufnagel into the descending thoracic aorta of patients with severe aortic regurgitation. The Starr caged ball mechanical prosthesis was designed for intracardiac replacement of an abnormal cardiac valve. The peripheral flow ball valve was followed by hydraulically superior and less thrombogenic central flow monoleaflet or bileaflet mechanical valves, and by homograft and heterograft bioprosthetic valves. Improved methods of preparing exogenous bioprostheses and innovative techniques of aortic valve reconstruction are evolving. Cardiac catheterization as a therapeutic intervention is routinely applied to stenotic mitral, aortic and pulmonary valves, and transcatheter replacement of an abnormal pulmonary valve is now a reality.</p>","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079778","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Perspectives on diseases of the thoracic aorta. 胸主动脉疾病的观点。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079786
John A Elefteriades
{"title":"Perspectives on diseases of the thoracic aorta.","authors":"John A Elefteriades","doi":"10.1159/000079786","DOIUrl":"https://doi.org/10.1159/000079786","url":null,"abstract":"","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"75-86"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079786","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Valve repair versus replacement when aortic regurgitation is caused by aortic root aneurysms: relative advantages and disadvantages and the impact of decision on surgical indications. 主动脉根部动脉瘤引起主动脉返流时瓣膜修复与置换术:相对优势和劣势以及决定对手术指征的影响。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079783
Leonard N Girardi
{"title":"Valve repair versus replacement when aortic regurgitation is caused by aortic root aneurysms: relative advantages and disadvantages and the impact of decision on surgical indications.","authors":"Leonard N Girardi","doi":"10.1159/000079783","DOIUrl":"https://doi.org/10.1159/000079783","url":null,"abstract":"","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"48-56"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079783","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of myocardial damage in regurgitant valvular disease. 反流性瓣膜病的心肌损害评价。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079784
Jagat Narula
{"title":"Assessment of myocardial damage in regurgitant valvular disease.","authors":"Jagat Narula","doi":"10.1159/000079784","DOIUrl":"https://doi.org/10.1159/000079784","url":null,"abstract":"","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079784","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ventricular arrhythmias in mitral regurgitation: frequency, clinical and prognostic importance, management before and after mitral valve surgery. 二尖瓣返流引起的室性心律失常:频率,临床和预后重要性,二尖瓣手术前后的处理。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079789
Clare Hochreiter, Jeffrey S Borer, Andrew Yin, Phyllis G Supino, Edmund M Herrold, Karl Krieger, O Wayne Isom
{"title":"Ventricular arrhythmias in mitral regurgitation: frequency, clinical and prognostic importance, management before and after mitral valve surgery.","authors":"Clare Hochreiter,&nbsp;Jeffrey S Borer,&nbsp;Andrew Yin,&nbsp;Phyllis G Supino,&nbsp;Edmund M Herrold,&nbsp;Karl Krieger,&nbsp;O Wayne Isom","doi":"10.1159/000079789","DOIUrl":"https://doi.org/10.1159/000079789","url":null,"abstract":"","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"108-11"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079789","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Valve surgery in the asymptomatic patient with aortic regurgitation: current indications and the effect of change rates in objective measures. 无症状主动脉瓣返流患者的瓣膜手术:当前适应症和客观指标变化率的影响。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079782
Jeffrey S Borer, Phyllis G Supino, Clare Hochreiter, Edmund M Herrold, Andrew Yin, Karl Krieger, O Wayne Isom
{"title":"Valve surgery in the asymptomatic patient with aortic regurgitation: current indications and the effect of change rates in objective measures.","authors":"Jeffrey S Borer,&nbsp;Phyllis G Supino,&nbsp;Clare Hochreiter,&nbsp;Edmund M Herrold,&nbsp;Andrew Yin,&nbsp;Karl Krieger,&nbsp;O Wayne Isom","doi":"10.1159/000079782","DOIUrl":"https://doi.org/10.1159/000079782","url":null,"abstract":"","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"36-47"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079782","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Surgery for atrioventricular septal defects. 房室间隔缺损的外科治疗。
Advances in Cardiology Pub Date : 2004-01-01 DOI: 10.1159/000079792
Jan M Quaegebeur, Rubin S Cooper
{"title":"Surgery for atrioventricular septal defects.","authors":"Jan M Quaegebeur,&nbsp;Rubin S Cooper","doi":"10.1159/000079792","DOIUrl":"https://doi.org/10.1159/000079792","url":null,"abstract":"","PeriodicalId":50954,"journal":{"name":"Advances in Cardiology","volume":" ","pages":"127-32"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000079792","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40881094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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