{"title":"In vitro assays for drug testing: continuous cell lines.","authors":"C Clarysse, J Fevery, S H Yap","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50942,"journal":{"name":"Acta Gastro-Enterologica Belgica","volume":"63 2","pages":"213-5"},"PeriodicalIF":1.5,"publicationDate":"2000-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21764662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"T.I.P.S.: follow-up imaging and revision procedure.","authors":"T Puttemans, E Agneessens, J Mathieu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>TIPS patency can be assessed by different imaging techniques: angiography, color Doppler sonography, CT angiography, scintigraphy. Percutaneous angiography with measurement of the portocaval pressure gradient is the gold standard in the diagnosis of shunt failure, but, because its invasive nature and the necessity of frequent control of the shunt function, a noninvasive procedure is preferable for routine checkup. Color Doppler sonography in intervals of 3 to 6 months, with the use of different criteria, is considered as an accurate imaging technique with a high degree of sensitivity and specificity to evaluate TIPS patency. Angiography is indicated when CDS is not successful or in each clinical recurrence. Revision procedure may restore shunt efficiency and is indicated when the TIPS patency is compromised.</p>","PeriodicalId":50942,"journal":{"name":"Acta Gastro-Enterologica Belgica","volume":"63 2","pages":"174-8"},"PeriodicalIF":1.5,"publicationDate":"2000-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21764645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Denis, M Dedobbeleer, T Collet, J Petit, M Jamoulle, A Hayani, R Brenard
{"title":"High prevalence of hepatitis C virus infection in Belgian intravenous drug users and potential role of the \"cotton-filter\" in transmission: the GEMT Study.","authors":"B Denis, M Dedobbeleer, T Collet, J Petit, M Jamoulle, A Hayani, R Brenard","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Aims: </strong>To estimate viral seroprevalences for HCV, HBV and HIV among belgian intravenous (IVDU) and non intravenous (non-IVDU) drug users; to assess risk factors for HCV infection in IVDU; to assess feasibility of chronic hepatitis C follow-up in this population.</p><p><strong>Design: </strong>Cross-sectional study. Demographic and behavioural characteristics were obtained by a standardized questionnaire. Serum samples were tested for HCV, HBV and HIV.</p><p><strong>Subjects and setting: </strong>329 patients (244 IVDU and 85 non-IVDU) attending ten general practitioners in 1995.</p><p><strong>Results: </strong>HCV seroprevalence was 78.3%; it was 35.7% for HBV and 0.9% for HIV in IVDU, vs 2.4%, 8.3% and 0%, respectively, in non-IVDU. In logistic regression analysis, independent risk factors for HCV infection were: 1/sharing of syringes and/or of \"cottons\" used as filters (adjusted prevalence odds ratio [POR] = 31.7; 95% confidence interval [CI] = 9.8-102.5), 2/duration of injecting upper than one month (adjusted POR = 8.6; CI = 3.0-24.7) and 3/age (adjusted POR = 1.2 by year of difference; CI = 1.0-1.3). A biochemical follow-up was obtained in 70% of HCV seropositive users; 79.5% of them had chronic hepatitis C (mean value of ALT = 3.5 times upper normal value, range 1.1-23.0). Among these, 24.7% went through liver biopsy during the three years follow-up period of the study.</p><p><strong>Conclusions: </strong>HCV seroprevalence is very high among belgian IVDU. Prevention strategies have to focus on neophytes injectors. They must be urgently revisited for what concern needles/syringes exchange programs: \"cottons\" must be included. Follow-up and treatment of chronic hepatitis C seem to be poorly effective among drug users.</p>","PeriodicalId":50942,"journal":{"name":"Acta Gastro-Enterologica Belgica","volume":"63 2","pages":"147-53"},"PeriodicalIF":1.5,"publicationDate":"2000-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21764752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proceedings of the International Symposium on Viral Hepatitis Beyond the Millennium. 9-11 December 1999, Leuven, Belgium.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50942,"journal":{"name":"Acta Gastro-Enterologica Belgica","volume":"63 2","pages":"179-235"},"PeriodicalIF":1.5,"publicationDate":"2000-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21854810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stenting of upper and lower GI tract obstruction.","authors":"C L Zollikofer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50942,"journal":{"name":"Acta Gastro-Enterologica Belgica","volume":"63 2","pages":"165-8"},"PeriodicalIF":1.5,"publicationDate":"2000-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21764643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hepatitis C virus and transplantation.","authors":"F Durand, P Marcellin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50942,"journal":{"name":"Acta Gastro-Enterologica Belgica","volume":"63 2","pages":"219-20"},"PeriodicalIF":1.5,"publicationDate":"2000-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21764660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}