IgMin Research最新文献

{"title":"Levetiracetam-induced Rhabdomyolysis - A Rare Complication","authors":"Khan Ayisha Farooq, Shaikh Naeemuddin, Abdy Faryal, Kanwar Dureshahwar","doi":"10.61927/igmin228","DOIUrl":"https://doi.org/10.61927/igmin228","url":null,"abstract":"Background: Levetiracetam is an anti-epileptic drug that works by modulation of synaptic neurotransmitter release through binding to the synaptic vesicle protein 2A. Levetiracetam is generally well tolerated. Common side effects of levetiracetam include lethargy, drowsiness, headaches, and mood changes. Rhabdomyolysis and an increase in Creatine Kinase (CK) levels are one of the rarely reported effects of levetiracetam. Case presentation: We present a case of a 20-year-old patient with previously known epilepsy (non-compliant with medicine) who presented with a seizure. The patient was given 1 gram of levetiracetam in the emergency department and was kept at a maintenance dose of 500 mg twice a day. The workup revealed acute kidney injury and raised levels of creatinine kinase that peaked at 19,757 IU/L 72 hours after levetiracetam was started. Levetiracetam was later switched to lamotrigine and aggressive intravenous hydration was done. Gradual improvement of CK level was noted accompanied by improvement in renal function. Conclusion: Only a few cases of levetiracetam-induced rhabdomyolysis have been reported worldwide. Our case report highlights the importance of monitoring creatinine and CK levels while treating patients with levetiracetam as rhabdomyolysis can be asymptomatic with a rise in CK levels only.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141816391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomimetic Synthesis of Calcium Carbonate in Bile in the presence of Amino Acids","authors":"Golovanova Olga","doi":"10.61927/igmin227","DOIUrl":"https://doi.org/10.61927/igmin227","url":null,"abstract":"Thermodynamic and experimental modeling of calcium carbonate crystallization in a model solution of human bile has been carried out. The process of calcium carbonate (calcite and vaterite) crystallization from solutions containing bile has been studied. It is shown that differences in the phase and group composition of the samples arise depending on the synthesis parameters. It has been established that in the presence of 1 wt. % bile, calcite is formed, and an increase in the concentration of bile in the initial solution from 5 to 100 wt. % contributes to the crystallization of vaterite. It is shown that the mass of the solid phase increases with an increase in the concentration of bile in the initial solution. The dissolution of the synthesized samples was performed in 0.9 wt. % NaCl solution and 0.05 M EDTA solution. It was found that the presence of bile components in the composition of solid samples reduces the rate of their dissolutions.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141824181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Imperative for Modern Public Cloud Providers to Upgrade Their Data Centers","authors":"Sajid Taha","doi":"10.61927/igmin225","DOIUrl":"https://doi.org/10.61927/igmin225","url":null,"abstract":"This study explores the imperative to modernize cloud computing in response to evolving technological landscapes and business demands. The research examines key areas requiring urgent attention to maintain competitive edge and operational efficiency in the digital era. We investigate the critical need for data center upgrades to accommodate emerging technologies and increased workloads. The study also delves into enhanced security measures and data privacy compliance protocols necessary to protect sensitive information in an increasingly complex threat environment. Furthermore, we analyze strategies to meet the growing demand for performance and scalability, ensuring that cloud infrastructure can adapt to fluctuating business needs. The research emphasizes the importance of maintaining system reliability to minimize downtime and maximize productivity. Additionally, we explore the potential of hybrid cloud integration to enable innovation and reduce costs. The purpose of this study is to provide a comprehensive overview of the challenges and opportunities in modernizing cloud computing, offering insights for organizations seeking to optimize their cloud strategies. Key findings highlight the significance of proactive infrastructure management, the adoption of advanced security frameworks, and the implementation of flexible, scalable architectures. This research contributes to the body of knowledge on cloud computing modernization, serving as a valuable resource for IT professionals, business leaders, and researchers in the field.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Low Pesticide Doses on Fusarium Molds","authors":"Ursan Mihaela, Boiu-Sicuia Oana-Alina, Crăinescu Ioana Irina, Cornea Călina Petruța","doi":"10.61927/igmin226","DOIUrl":"https://doi.org/10.61927/igmin226","url":null,"abstract":"The agricultural sector is a large consumer of synthetic chemical products, especially fertilizers and plant protection products. Therefore, an emerging concern nowadays is to reduce chemicals’ use in agriculture. One of the approaches is to reduce the doses of plant protection products, as much as possible, while keeping the treatments’ efficacy. The present work presents the antifungal action of three commercial plant protection products, tested at recommended as well as reduced doses, against important phytopathogenic molds of the Fusarium genus. In vitro, results have shown that two of the tested products could be used at reduced doses while keeping their antifungal activity. The commercial pesticide containing prothioconazole 53 g/L, spiroxamine 224 g/L, and tebuconazole 148 g/L mixture was able to inhibit completely the growth of three virulent F. culmorum strains, even when fungicide treatment was applied in 25% reduced dose. Lower efficacy was seen on F. graminearum strains, however, there were no significant differences (p < 0.05) between the commercially recommended dose and the 25% reduced dose. Another efficient pesticide in Fusarium control contains triadimenol 43 g/L, spiroxamine 250 g/L, and tebuconazole 167 g/L. Tested in a reduced dose (28.6% less than the commercial recommended dose) it completely inhibited the F. graminearum Fg183 (DSM 4527) strain and inhibited the growth of various F. culmorum strains with at least 97.50% efficacy. However, there are some fungal strains, such as the aggressive F. graminearum Fg96 strains that were less susceptible to pesticide treatments even at commercially recommended doses of fungicides.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141829772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Sustainable Development, Economy and Poverty","authors":"Tenorio Antonio Oñate, del os Santos Oñate Tenorio María","doi":"10.61927/igmin224","DOIUrl":"https://doi.org/10.61927/igmin224","url":null,"abstract":"Throughout this document, the opportunity is provided to show the relationship between sustainable development and economic growth, focusing on their definitions, their disparity, and their consequences, at the same time it gives us a vision of the evolution of the importance of economic development and of their inability to solve the problem of poverty. The satisfaction of the needs of the human being, would go through seeking a balance between economic growth, care for the environment, and social welfare, a breakdown of this balance has put into question the traditional model of economic development, in which they raise fundamental questions where the very accumulation of wealth creates poverty. The bibliographic search carried out has led us to obtain a series of conclusions on the proposed terms, in which a robust social solidarity economy would lead us to the eradication of poverty. This work takes us to a reflection on the sustainability of natural resources, the viability of the economic development model, and its rate of growth in a context of globalization in which localities are left behind, but without being forgotten, although they have no involvement in models that meet their development needs.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141830858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lattice Boltzmann Method without Invoking the M << 1 Assumption","authors":"Ronald So","doi":"10.61927/igmin223","DOIUrl":"https://doi.org/10.61927/igmin223","url":null,"abstract":"When a Maxwellian distribution is assumed for the distribution function in the BGK-type modelled BE, it will give rise to the Euler equations if it is the first-order approximation in the Chapman-Enskog method. Then the second-order equations will yield the N-S equations. Most LBM developed to date are formulated based on the second-order equations. Consequently, the assumption of a flow Mach number M << 1 is inherent in this formulation. This approach creates an unnecessary restriction on the LBM that should be avoided if possible. An alternative approach is to formulate a new LBM by considering an equilibrium distribution function where the first-order approximations give rise to the N-S equations. Adopting this approach, a new LBM has been formulated. This new LBM gives reliable results when applied to simulate aeroacoustics, incompressible flows, and compressible flows with and without shocks. Good agreement with measurements and numerical data derived from DAS/DNA calculations is obtained.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141831908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Power of Artificial Intelligence for Improved Patient Outcomes, Ethical Practices and Overcoming Challenges","authors":"Almasri Imad-Addin","doi":"10.61927/igmin222","DOIUrl":"https://doi.org/10.61927/igmin222","url":null,"abstract":"Artificial Intelligence (AI) is revolutionizing healthcare by enhancing patient outcomes, reducing costs, and increasing the efficiency of medical professionals. This mini-review explores the diverse applications of AI in healthcare, including disease diagnosis, personalized treatment plans, and patient survival rate predictions. AI technologies such as Machine Learning (ML), deep learning, Natural Language Processing (NLP), and Robotic Process Automation (RPA) are becoming integral to modern healthcare practices. These technologies enable early disease detection, particularly in cases like cancer, by analyzing medical images and patient data, leading to more effective and personalized treatment strategies. Additionally, AI can predict patient outcomes by analyzing large datasets from electronic health records, providing valuable insights that can inform clinical decisions. However, the integration of AI in healthcare also presents significant ethical challenges. Issues such as data privacy, algorithmic bias, lack of transparency, and the potential for increased health inequalities need to be addressed. The World Health Organization (WHO) has provided guidelines emphasizing the ethical use of AI, highlighting the importance of designing AI systems that respect human rights and promote equity. As AI continues to advance, it is crucial to ensure its responsible and transparent use to maximize benefits and minimize risks. This review underscores the transformative potential of AI in healthcare while calling for vigilant ethical considerations to ensure that AI technologies are implemented in a manner that enhances patient care and upholds ethical standards.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141831844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Stacking Sequence and Ply Orientation with Central Hole on Tensile Behavior of Glass Fiber-polyester Composite","authors":"Eladawi Ahmad E","doi":"10.61927/igmin221","DOIUrl":"https://doi.org/10.61927/igmin221","url":null,"abstract":"An experimental investigation was carried out to study the effect of circular cross-holes on the failure behavior of unidirectional glass fiber reinforced with unsaturated polyester resin composites, varying cross-ply laminates that were subjected to axial tensile load. This paper deals with the effects of the circular notch and the number of plies on nominal tensile and net tensile strengths. Tensile strengths were investigated for composites with cross-ply([0/90]. [90°/0°/90°] and [0°/90°/0°].90°), orientation and varying the laminate layers with a central hole, and effects of volume fraction and number of ply on mechanical properties for un-notched (smooth) and notched specimens were also studied. The results showed that increasing the number of plies has a marginal effect on tensile strength values. The fraction of volume has significant effects and for increasing the number of plies about 9% decreases in nominal tensile strength and about 11% decrease in the net tensile strength was observed. The same results were obtained with finite element analysis.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Access to Healthcare - A Prominent Challenge in Public Health","authors":"Al-Khatib Inas, Awad Mahmoud, Ndiaye Malick","doi":"10.61927/igmin220","DOIUrl":"https://doi.org/10.61927/igmin220","url":null,"abstract":"Among the important public health socioeconomic factors are Income and Social Status, Education, Occupation and Working Conditions, Access to Healthcare, Physical Environment, Social Support Network, Culture, and Community. A review was conducted based on other published articles and existing literature with an aim to identify what are the socioeconomic determinants of public health, in particular, determine the dimensions of access to healthcare determinants and outline strategies available to enhance access to healthcare. The results indicated that countries can adopt ten (10) key improvement strategies of public health that can support answering this main research question ‘How can Access to Healthcare socioeconomic determinants be improved?’","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Auxological Status of Modern Primary School Students of Nizhny Novgorod Region","authors":"Aleksandrovich Kalyuzhny Evgeniy, Vasilievna Mukhina Irina, Sergeevna Bogomolova Elena, Anatolyevna Galova Elena, Andreevna Puzhak Svetlana, Sergeevna Baklanova Ekaterina","doi":"10.61927/igmin219","DOIUrl":"https://doi.org/10.61927/igmin219","url":null,"abstract":"The article describes the characteristics of the resulting effector auxological morpho-functional status of primary school students, differentiated by gender and administrative-territorial characteristics. The objectives of the study included studying the auxological status of children adolescents, and primary school students in the Nizhny Novgorod region in the context of the peculiarities of the exoenvironment of residence in urban and rural areas. Materials and methods: Own data served as a source of anthropometry and physiometry indicators of the objective population of the region. The analysis of anthropological indicators was carried out by discretizing data sets that state an objective picture of auxological indicators at the regional level, taking into account the peculiarities of anthropogenic loads characteristic of the place of residence of the observed population groups. To quantify the values ​​and statistical differences in indicators by age, gender, and administrative characteristics, the median, standard deviation, and criteria were used: Fisher, Wilks, and Mahalanobis, with an error of differences at p < 0.05. Results: The stability of the age-sex evolution of auxological indicators is shown; the age-sex and territorial dimorphism of total body sizes is shown at 7-10 years of age, with residents of rural areas lagging in the observed indicators. Hemodynamic indicators in both boys and girls significantly prevail among students living in the metropolis relative to their rural counterparts, except diastolic blood pressure. Variance analytics shows differences in the distributions of anthropometry and hemodynamics, both by age and by the urbanization factor at p < 0.001. In the observed age period, at the initial stage, hemodynamic indicators act primarily as modifiers of the metropolis and rural groups. From the age of ten, according to the standardized coefficients of discriminant functions, according to the first canonical variable, the division of series also occurs according to anthropometric characteristics, among which the greatest contribution to the division of groups is made by body weight and body length, and the hemodynamic characteristic - diastolic blood pressure - has also proven to be decisive. Conclusion: Primary school students living in rural areas and in the metropolis of the Nizhny Novgorod region determine the observed indicators ambiguously; if residents of the metropolis state greater results for all observed auxological indicators, then rural peers demonstrate, while lagging in all observed indicators, greater indicators of diastolic blood pressure, which suggests a strain on adaptation mechanisms central character.","PeriodicalId":509147,"journal":{"name":"IgMin Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}