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Advances in Enzymology and Related Subjects最新文献

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Xenobiotic efflux in bacteria and fungi: a genomics update. 细菌和真菌的外源外排:基因组学的更新。
Advances in Enzymology and Related Subjects Pub Date : 2011-01-01 DOI: 10.1002/9780470920541.ch6
Ravi D Barabote, Jose Thekkiniath, Richard E Strauss, Govindsamy Vediyappan, Joe A Fralick, Michael J San Francisco
{"title":"Xenobiotic efflux in bacteria and fungi: a genomics update.","authors":"Ravi D Barabote, Jose Thekkiniath, Richard E Strauss, Govindsamy Vediyappan, Joe A Fralick, Michael J San Francisco","doi":"10.1002/9780470920541.ch6","DOIUrl":"https://doi.org/10.1002/9780470920541.ch6","url":null,"abstract":"","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"77 ","pages":"237-306"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/9780470920541.ch6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29953017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Effects and analysis of transglutamination on protein aggregation and clearance in neurodegenerative diseases. 转谷氨酰胺对神经退行性疾病中蛋白质聚集和清除的影响及分析。
Advances in Enzymology and Related Subjects Pub Date : 2011-01-01 DOI: 10.1002/9781118105771.ch8
Zoltán Nemes
{"title":"Effects and analysis of transglutamination on protein aggregation and clearance in neurodegenerative diseases.","authors":"Zoltán Nemes","doi":"10.1002/9781118105771.ch8","DOIUrl":"https://doi.org/10.1002/9781118105771.ch8","url":null,"abstract":"","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"78 ","pages":"347-83"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/9781118105771.ch8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30366115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Inosine 5'-monophosphate dehydrogenase. 肌苷5'-单磷酸脱氢酶。
Advances in Enzymology and Related Subjects Pub Date : 2009-05-26 DOI: 10.1002/9780470392881.CH1
M. Pimkin, G. D. Markham
{"title":"Inosine 5'-monophosphate dehydrogenase.","authors":"M. Pimkin, G. D. Markham","doi":"10.1002/9780470392881.CH1","DOIUrl":"https://doi.org/10.1002/9780470392881.CH1","url":null,"abstract":"","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"2 1","pages":"1-53"},"PeriodicalIF":0.0,"publicationDate":"2009-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76993708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Natural product glycosyltransferases: properties and applications. 天然产物糖基转移酶:性质和应用。
Advances in Enzymology and Related Subjects Pub Date : 2009-01-01 DOI: 10.1002/9780470392881.ch2
Gavin J Williams, Jon S Thorson
{"title":"Natural product glycosyltransferases: properties and applications.","authors":"Gavin J Williams, Jon S Thorson","doi":"10.1002/9780470392881.ch2","DOIUrl":"https://doi.org/10.1002/9780470392881.ch2","url":null,"abstract":"","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"76 ","pages":"55-119"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/9780470392881.ch2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27825819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 53
Combinatorial and evolutionary design of biosynthetic reaction sequences. 生物合成反应序列的组合和进化设计。
Advances in Enzymology and Related Subjects Pub Date : 2009-01-01 DOI: 10.1002/9780470392881.ch3
Ethan T Johnson, Erik Holtzapple, Claudia Schmidt-Dannert
{"title":"Combinatorial and evolutionary design of biosynthetic reaction sequences.","authors":"Ethan T Johnson, Erik Holtzapple, Claudia Schmidt-Dannert","doi":"10.1002/9780470392881.ch3","DOIUrl":"https://doi.org/10.1002/9780470392881.ch3","url":null,"abstract":"","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"76 ","pages":"121-50, 12 p following 150"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27825820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Inosine 5'-monophosphate dehydrogenase. 肌苷5'-单磷酸脱氢酶。
Advances in Enzymology and Related Subjects Pub Date : 2009-01-01
Maxim Pimkin, George D Markham
{"title":"Inosine 5'-monophosphate dehydrogenase.","authors":"Maxim Pimkin, George D Markham","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"76 ","pages":"1-53"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27825818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in enzymology and related areas of molecular biology. Preface. 酶学及分子生物学相关领域研究进展。前言。
Advances in Enzymology and Related Subjects Pub Date : 2009-01-01 DOI: 10.1002/9780470122945
E. Toone
{"title":"Advances in enzymology and related areas of molecular biology. Preface.","authors":"E. Toone","doi":"10.1002/9780470122945","DOIUrl":"https://doi.org/10.1002/9780470122945","url":null,"abstract":"","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"38 1","pages":"ix-x"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74303604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Advances in enzymology and related areas of molecular biology. Preface. 酶学及分子生物学相关领域研究进展。前言。
Advances in Enzymology and Related Subjects Pub Date : 2009-01-01
Eric J Toone
{"title":"Advances in enzymology and related areas of molecular biology. Preface.","authors":"Eric J Toone","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"76 ","pages":"ix-x"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27825817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in microbial synthesis of natural products and biofuels. 微生物合成天然产物和生物燃料的趋势。
Advances in Enzymology and Related Subjects Pub Date : 2009-01-01 DOI: 10.1002/9780470392881.ch4
Joseph A Chemier, Zachary L Fowler, Mattheos A G Koffas, Effendi Leonard
{"title":"Trends in microbial synthesis of natural products and biofuels.","authors":"Joseph A Chemier,&nbsp;Zachary L Fowler,&nbsp;Mattheos A G Koffas,&nbsp;Effendi Leonard","doi":"10.1002/9780470392881.ch4","DOIUrl":"https://doi.org/10.1002/9780470392881.ch4","url":null,"abstract":"<p><p>Ever since the era of recombinant DNA technology for natural product biosynthesis emerged (292), microorganisms are increasingly becoming common production platforms for many fine chemicals, including natural products and biofuels, that are currently being produced either through chemical methods or using plant and organ cell cultures. The rapid elucidation of biosynthetic pathways made possible through advanced genomic tools has made natural products again the molecules of choice for drug development. Indeed, half of the drugs currently in clinical use are natural products and it is expected that the market size of biotechnology-derived small molecules will exceed billion U.S.$100 in 2010 and billion U.S.$400 in 2030 (3, 293). There are still many challenges facing the use of microorganisms for high-value chemical synthesis. For example, further developments of recent advances are necessary to make a fermentation-based biobutanol industry that can compete effectively with petrochemically derived butanol. As such, we believe that biocatalyst factories such as E. coli and S. cerevisiae will not only continue to be highly attractive alternatives to traditional chemical manufacturing but the application of powerful systems biology approaches will facilitate their expanded role in industrial applications (294-296).</p>","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"76 ","pages":"151-217"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27825821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Molecular paleoscience: systems biology from the past. 分子古科学:来自过去的系统生物学。
Advances in Enzymology and Related Subjects Pub Date : 2007-01-01 DOI: 10.1002/9780471224464.ch1
Steven A Benner, Slim O Sassi, Eric A Gaucher
{"title":"Molecular paleoscience: systems biology from the past.","authors":"Steven A Benner,&nbsp;Slim O Sassi,&nbsp;Eric A Gaucher","doi":"10.1002/9780471224464.ch1","DOIUrl":"https://doi.org/10.1002/9780471224464.ch1","url":null,"abstract":"<p><p>Experimental paleomolecular biology, paleobiochemistry, and paleogenetics are closely related emerging fields that infer the sequences of ancient genes and proteins from now-extinct organisms, and then resurrect them for study in the laboratory. The goal of paleogenetics is to use information from natural history to solve the conundrum of modern genomics: How can we understand deeply the function of biomolecular structures uncovered and described by modern chemical biology? Reviewed here are the first 20 cases where biomolecular resurrections have been achieved. These show how paleogenetics can lead to an understanding of the function of biomolecules, analyze changing function, and put meaning to genomic sequences, all in ways that are not possible with traditional molecular biological studies.</p>","PeriodicalId":50865,"journal":{"name":"Advances in Enzymology and Related Subjects","volume":"75 ","pages":"1-132, xi"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/9780471224464.ch1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26405121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 67
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