Annales D Urologie最新文献_第6页

Introductory clinical case of the symposium 研讨会的介绍性临床病例

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/S0003-4401(06)80013-6

de François Richard , Guy Vallancien

引用次数: 0

Index des auteurs 作者索引

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/S0003-4401(06)00134-3

引用次数: 0

Localized prostate cancer. What to say to the patient? 局限性前列腺癌。对病人说什么?

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/S0003-4401(06)80014-8

P. Coloby

引用次数: 0

Localized prostate cancer. Local treatment and what place for lymphadenectomy 局限性前列腺癌。局部治疗和在什么地方进行淋巴结切除术

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/S0003-4401(06)80015-X

D. Rossi

{"title":"Localized prostate cancer. Local treatment and what place for lymphadenectomy","authors":"D. Rossi","doi":"10.1016/S0003-4401(06)80015-X","DOIUrl":"10.1016/S0003-4401(06)80015-X","url":null,"abstract":"<div><p>The pretreatment PSA level, the Gleason score, the presence of lymph-node metastases, the status of surgical positive margins are poor pathological risk factors for patients who have a pathologic stage T3 prostate cancer. The increase in PSA level during the year prior to diagnostic is associated with the risk of death due to prostate cancer following radical prostatectomy or external beam radiation therapy. The assessment of locoregional extension is indicated for such patients. The extended pelvic lymphadenectomy remains the most accurate procedure for a correct staging of the detection of nodal involvement in these patients with high-risk localized prostate cancer. For such patients with a high-risk of progression and, whose the life expectancy is greater than 10 years, treatment must be a combined modality therapy since radical prostatectomy alone correlates with a poor clinical outcome. Adjuvant hormonal therapy following local curative treatment by prostatectomy (or radiotherapy) needs to be often considered. Collegial decision-making is by far the most appropriate setting for the discussion among medical specialists of these complex clinical cases for patients often having associated medical conditions and whose adjuvant treatment will have a significant impact of their future quality of life.</p></div>","PeriodicalId":50783,"journal":{"name":"Annales D Urologie","volume":"40 ","pages":"Pages S24-S28"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0003-4401(06)80015-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26205728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Difficult clinical cases in prostate cancer: multidisciplinary staff, the rational principles of adjuvant therapy and other therapeutic options 前列腺癌临床疑难病例:多学科人员、合理的辅助治疗原则及其他治疗选择

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/S0003-4401(06)80018-5

M. Zerbib , K. Fizazi , C. Hennequin , A. Villers

{"title":"Difficult clinical cases in prostate cancer: multidisciplinary staff, the rational principles of adjuvant therapy and other therapeutic options","authors":"M. Zerbib , K. Fizazi , C. Hennequin , A. Villers","doi":"10.1016/S0003-4401(06)80018-5","DOIUrl":"10.1016/S0003-4401(06)80018-5","url":null,"abstract":"<div><p>Difficult clinical cases of locally advanced prostate cancer at high-risk of progression should be discussed during a collegial decision-making process with different clinical specialists (surgeon, radiotherapist, oncologist, chemotherapist). Scientific consensus exists to give an adjuvant therapy after initial curative local treatment in patients with unfavourable prognostic features. For patients with locally advanced prostate cancer extending beyond the capsule (pT3) or with positive surgical margins, studies have shown that immediate postoperative radiotherapy is to eradicate the microscopic disease left in the surgical bed. Studies have shown the potential benefit of cytotoxic chemotherapy in terms of overall survival and median time to progression in patients with metastatic hormone-refractory prostate cancer. Active clinical research is underway to study neoadjuvant systemic chemotherapy before radical prostatectomy. There are also currently several clinical trials that are investigating the addition of chemotherapy in patients at high-risk of progression in the postprostatectomy setting. Antiandrogen therapy after radical prostatectomy has been shown in randomised studies to significantly reduce the risk of objective clinical progression in patients with high-risk localized prostate cancer. Immediate hormonal therapy with bicalutamide is a valuable therapeutic option in men having prostate cancer with such clinicopathological features.</p></div>","PeriodicalId":50783,"journal":{"name":"Annales D Urologie","volume":"40 ","pages":"Pages S35-S41"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0003-4401(06)80018-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26205731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Index des mots-clés 关键词索引

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/S0003-4401(06)00135-5

引用次数: 0

Management of gynecomastia induced by bicalutamide 比卡鲁胺致男性乳房发育症的治疗

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/S0003-4401(06)80021-5

E. Haddad

引用次数: 8

Cancer de la prostate du sujet âgé 老年患者的前列腺癌

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/j.anuro.2006.09.002

M. Waldert MD, B. Djavan MD

引用次数: 2

Marqueurs biologiques du cancer de la prostate 前列腺癌的生物标志物

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/j.anuro.2006.09.001

C. Seitz, B. Djavan

引用次数: 8

Facteurs de risque de marges chirurgicales positives après prostatectomie radicale : mise au point 根治性前列腺切除术后手术边缘阳性的危险因素:重点

Annales D Urologie Pub Date : 2006-12-01 DOI: 10.1016/j.anuro.2006.09.004

A. Descazeaud, M. Zerbib, M. Peyromaure

{"title":"Facteurs de risque de marges chirurgicales positives après prostatectomie radicale : mise au point","authors":"A. Descazeaud, M. Zerbib, M. Peyromaure","doi":"10.1016/j.anuro.2006.09.004","DOIUrl":"10.1016/j.anuro.2006.09.004","url":null,"abstract":"<div><p>The presence of positive surgical margins on radical prostatectomy specimen is an adverse prognostic factor. Parameters supposed to influence surgical margin status includes pathology method analysis, surgical technique, tumoural and non tumoural patient parameters, and neoadjuvant hormonal therapy. Regarding the surgical technique, surgeon's experience and neuro-vascular bundles preservation are the most important factors of margin status, whereas surgical approach, bladder neck conservation, intraoperative frozen analysis, and bleeding are minor factors. Non tumoural patient parameters influencing surgical margin status include patient's age and weight, and prostate gland weight. For tumoural parameters, pathological stage and tumour volume are more important factors than the tumour grade and PSA. Five preoperative tumoural risk factors of positive surgical margins are particularly important, including abnormal digital rectal examination, preoperative PSA>10ng/mL, biopsy Gleason score ≥7, number of positive biopsy cores≥2, and suspicion of extraprostatic extension on radical prostatectomy specimen.</p></div>","PeriodicalId":50783,"journal":{"name":"Annales D Urologie","volume":"40 6","pages":"Pages 342-348"},"PeriodicalIF":0.0,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.anuro.2006.09.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26482294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4