Best Practice & Research Clinical Obstetrics & Gynaecology最新文献

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Hormonal methods for fertility regulation 调节生育的激素方法
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-09-22 DOI: 10.1016/j.bpobgyn.2025.102671
Raymond Hang-Wun Li
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引用次数: 0
Hormonal contraception in perimenopausal women 围绝经期妇女的激素避孕
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-09-02 DOI: 10.1016/j.bpobgyn.2025.102655
Sara Whitburn , Kathleen McNamee , Clare Boerma , Deborah Bateson
{"title":"Hormonal contraception in perimenopausal women","authors":"Sara Whitburn ,&nbsp;Kathleen McNamee ,&nbsp;Clare Boerma ,&nbsp;Deborah Bateson","doi":"10.1016/j.bpobgyn.2025.102655","DOIUrl":"10.1016/j.bpobgyn.2025.102655","url":null,"abstract":"<div><div>Contraception can be an overlooked aspect of perimenopausal healthcare. While background fertility is low, pregnancies in those aged over 40 years present a higher risk both to the fetus and mother, and have a higher chance of ending in miscarriage or abortion, compared to pregnancies in younger women. This chapter provides a review of key issues related to hormonal contraception in the perimenopause and evaluates each method's effectiveness and safety at a stage of life when venous and cardiovascular disease risks increase. Suitability is assessed considering the person's needs, circumstances and contraindications. Attention is also given to non-contraceptive advantages of certain methods, such as management of perimenopausal symptoms, heavy bleeding and reduction of risks for certain cancers. By highlighting current research and clinical guidelines, this chapter aims to equip healthcare providers with knowledge to support perimenopausal women in making informed reproductive health decisions.</div></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"103 ","pages":"Article 102655"},"PeriodicalIF":4.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145026294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current challenges in fertility preservation 保存生育能力的当前挑战
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-08-08 DOI: 10.1016/j.bpobgyn.2025.102654
Richard A. Anderson
{"title":"Current challenges in fertility preservation","authors":"Richard A. Anderson","doi":"10.1016/j.bpobgyn.2025.102654","DOIUrl":"10.1016/j.bpobgyn.2025.102654","url":null,"abstract":"","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"103 ","pages":"Article 102654"},"PeriodicalIF":4.1,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intervention or expectant management for stage I twin-twin transfusion syndrome I期双胎输血综合征的干预或预期管理
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-07-31 DOI: 10.1016/j.bpobgyn.2025.102645
Raphael Bartin M.D. , Nikan Zargarzadeh M.D. , Mohammadamin Parsaei M.D. , Alireza A. Shamshirsaz M.D. , Julien J. Stirnemann M.D. , Stephen P. Emery M.D.
{"title":"Intervention or expectant management for stage I twin-twin transfusion syndrome","authors":"Raphael Bartin M.D. ,&nbsp;Nikan Zargarzadeh M.D. ,&nbsp;Mohammadamin Parsaei M.D. ,&nbsp;Alireza A. Shamshirsaz M.D. ,&nbsp;Julien J. Stirnemann M.D. ,&nbsp;Stephen P. Emery M.D.","doi":"10.1016/j.bpobgyn.2025.102645","DOIUrl":"10.1016/j.bpobgyn.2025.102645","url":null,"abstract":"<div><div>Selective fetoscopic laser photocoagulation of communicating vessels (SFPL) is well established as the first line of therapy for stage II-IV twin-twin transfusion syndrome (TTTS). The optimal management of stage I TTTS is less well-defined. While many stage I patients resolve spontaneously or remain stage I with good pregnancy outcomes, a majority progress to higher stages. Risk factors that differentiate those who will remain stable or regress vs. those who will progress are lacking. This has led some centers to offer SFLP to patients with stage I disease either immediately or after a period of close observation. The objective of this manuscript is to review the current evidence on the merits of laser treatment versus expectant management for stage I TTTS. A search of PubMed and Google Scholar using the keywords “stage I,” “twin transfusion,” and “management” was undertaken. The results of this review suggest that expectant management of stable, asymptomatic stage I TTTS is a reasonable first-line treatment, whereas selective fetoscopic laser photocoagulation is an appropriate first step in some circumstances. Treatment of stage I TTTS should remain an option in select patients.</div></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"102 ","pages":"Article 102645"},"PeriodicalIF":4.1,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decision-making and operative considerations for Ex-utero Intrapartum treatment (EXIT) 体外产内治疗(EXIT)的决策及手术考虑
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-07-25 DOI: 10.1016/j.bpobgyn.2025.102649
Scott Infusino , Nitin Sajankila , Elle Nuttall , Darrell L. Cass , Michael Puricelli , Inna N. Lobeck
{"title":"Decision-making and operative considerations for Ex-utero Intrapartum treatment (EXIT)","authors":"Scott Infusino ,&nbsp;Nitin Sajankila ,&nbsp;Elle Nuttall ,&nbsp;Darrell L. Cass ,&nbsp;Michael Puricelli ,&nbsp;Inna N. Lobeck","doi":"10.1016/j.bpobgyn.2025.102649","DOIUrl":"10.1016/j.bpobgyn.2025.102649","url":null,"abstract":"<div><div>The Ex-Utero Intrapartum Treatment (EXIT) is a method of delivery utilized in the setting of fetal anomalies that can lead to respiratory or cardiovascular compromise with the transition to extrauterine life. With multidisciplinary collaboration, delivery occurs with uterine relaxation to preserve placental function, allowing for appropriate intervention while the maternofetal interface is maintained. Multiple types of EXIT procedures are described in the literature that differ based on fetal indication and specific clinical goals. These include EXIT-to-airway, EXIT-to-resection, EXIT-to-extracorporeal membrane oxygenation (ECMO), and EXIT-to-ventricular pacing. When considering an EXIT procedure, fetal benefit must be weighed against maternal risk, and patients require thorough counseling to make an informed decision. In many cases, an individualized approach is necessary. The goal of this review is to provide an overview of the prenatal evaluation, risk stratification, and technical planning necessary for the various forms of EXIT procedures.</div></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"102 ","pages":"Article 102649"},"PeriodicalIF":4.1,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144772553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemolytic disease of the fetus and newborn: A review of pathophysiology, diagnosis, and management 胎儿和新生儿溶血性疾病:病理生理学、诊断和治疗的综述。
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-07-25 DOI: 10.1016/j.bpobgyn.2025.102646
Hajra Malik , E.J.T. (Joanne) Verweij , Hiba J. Mustafa
{"title":"Hemolytic disease of the fetus and newborn: A review of pathophysiology, diagnosis, and management","authors":"Hajra Malik ,&nbsp;E.J.T. (Joanne) Verweij ,&nbsp;Hiba J. Mustafa","doi":"10.1016/j.bpobgyn.2025.102646","DOIUrl":"10.1016/j.bpobgyn.2025.102646","url":null,"abstract":"<div><div>Hemolytic Disease of the Fetus and Newborn (HDFN) results from maternal alloantibodies attacking fetal red blood cells, leading to fetal anemia and potentially severe complications such as hydrops fetalis. Effective management relies on early detection through maternal antibody screening, fetal antigen testing, and close monitoring of fetal anemia. In cases of severe anemia, intrauterine transfusion (IUT) remains the primary intervention to improve fetal outcomes. Despite this, there is an urgent need for novel medical therapies to prevent or delay disease progression in pregnancies at risk for HDFN.</div></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"102 ","pages":"Article 102646"},"PeriodicalIF":4.1,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reverse innovation – South to North learnings in the provision of postpartum contraception: implementation in a high-income setting 反向创新——产后避孕的南向北学习:在高收入环境下的实施
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-07-25 DOI: 10.1016/j.bpobgyn.2025.102653
Anita Makins , Hifsa Mahmood , Katherine Talbot , Claire Hordern , Neda Taghinejadi , Ruth Houlden , Suzanna Bright , Sabaratnam Arulkumaran
{"title":"Reverse innovation – South to North learnings in the provision of postpartum contraception: implementation in a high-income setting","authors":"Anita Makins ,&nbsp;Hifsa Mahmood ,&nbsp;Katherine Talbot ,&nbsp;Claire Hordern ,&nbsp;Neda Taghinejadi ,&nbsp;Ruth Houlden ,&nbsp;Suzanna Bright ,&nbsp;Sabaratnam Arulkumaran","doi":"10.1016/j.bpobgyn.2025.102653","DOIUrl":"10.1016/j.bpobgyn.2025.102653","url":null,"abstract":"<div><div>This article outlines a unique example of reverse innovation. Lessons from low- and middle-income countries (LMICs) shaped healthcare practices in a high-income setting. We describe how the FIGO Postpartum Intrauterine Device Initiative, implemented across six LMICs, informed the development of a postpartum contraception program in a UK-based NHS trust. Despite the well-documented benefits of postpartum family planning (PPFP), implementing dedicated PPFP services in the UK has been challenging due to fragmented healthcare funding and cross service integration barriers. The COVID-19 pandemic created an urgent need for adaptation, providing a unique opportunity to rapidly establish a comprehensive local PPFP service. We outline how strategies from LMICs - including task-sharing, provider training, and policy advocacy - were directly applied to overcome these barriers and drive successful implementation. This case study highlights the potential of South-to-North knowledge transfer in driving healthcare innovation, improving contraceptive access, and underscores the importance of global collaboration and adaptive learning in reproductive healthcare.</div></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"102 ","pages":"Article 102653"},"PeriodicalIF":4.1,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144829234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Making fertility preservation happen for the transgender community 让跨性别群体的生育能力得以保留。
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-07-24 DOI: 10.1016/j.bpobgyn.2025.102652
Suset Rodriguez, Pasquale Patrizio
{"title":"Making fertility preservation happen for the transgender community","authors":"Suset Rodriguez,&nbsp;Pasquale Patrizio","doi":"10.1016/j.bpobgyn.2025.102652","DOIUrl":"10.1016/j.bpobgyn.2025.102652","url":null,"abstract":"<div><div>Transgender individuals, whose gender identity differs from their assigned sex at birth, may undergo gender-affirming hormone therapy (GAHT) and gender-affirming surgery (GAS) to alleviate gender dysphoria. These treatments often impact future reproductive potential, necessitating fertility preservation (FP) discussions. Healthcare guidelines from the American Society of Reproductive Medicine (ASRM), World Professional Association for Transgender Health (WPATH), and the Endocrine Society recommend counseling on FP options, which include oocyte, sperm, and embryo cryopreservation. Challenges remain, including the impact of gender dysphoria during FP processes, the recommended length of being off hormonal treatments, the financial burden, and limited data on future pregnancy outcomes. This chapter explores FP options for transgender individuals, including those with ovaries or testes, and addresses challenges to utilization.</div></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"102 ","pages":"Article 102652"},"PeriodicalIF":4.1,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fetal surgery for congenital diaphragmatic hernia in the post-TOTAL trial era 后total试验时代胎儿手术治疗先天性膈疝
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-07-24 DOI: 10.1016/j.bpobgyn.2025.102648
Linoy Batsry, Jimmy Espinoza, Eric Bergh
{"title":"Fetal surgery for congenital diaphragmatic hernia in the post-TOTAL trial era","authors":"Linoy Batsry,&nbsp;Jimmy Espinoza,&nbsp;Eric Bergh","doi":"10.1016/j.bpobgyn.2025.102648","DOIUrl":"10.1016/j.bpobgyn.2025.102648","url":null,"abstract":"<div><div>Today, prenatal therapy for congenital diaphragmatic hernia (CDH) primarily centers on fetoscopic endoluminal tracheal occlusion (FETO). This procedure involves the temporary occlusion of the fetal trachea to promote lung development. The TOTAL (Tracheal Occlusion to Accelerate Lung Growth) trial demonstrated a significant improvement in survival rates for fetuses with severe CDH following FETO. The outcomes of the TOTAL trial have sparked heightened interest in the FETO procedure, leading to the publication of numerous additional studies. Nevertheless, subsequent research has yielded inconsistent results outside of randomized controlled trials. This review examines the variations in patient selection, procedural techniques, and postnatal care that may contribute to this variability while also exploring potential future directions for the FETO procedure and prenatal therapy for CDH.</div></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"102 ","pages":"Article 102648"},"PeriodicalIF":4.1,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding, detecting, and managing the “late” anemia of hemolytic disease of the fetus and newborn 了解、检测和处理溶血性疾病对胎儿和新生儿的“晚期”贫血。
IF 4.1 2区 医学
Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-07-23 DOI: 10.1016/j.bpobgyn.2025.102650
Robert D. Christensen MD, Timothy M. Bahr MS, MD, Robin K. Ohls MD
{"title":"Understanding, detecting, and managing the “late” anemia of hemolytic disease of the fetus and newborn","authors":"Robert D. Christensen MD,&nbsp;Timothy M. Bahr MS, MD,&nbsp;Robin K. Ohls MD","doi":"10.1016/j.bpobgyn.2025.102650","DOIUrl":"10.1016/j.bpobgyn.2025.102650","url":null,"abstract":"<div><div>The “late” anemia of hemolytic disease of the fetus and newborn (HDFN), first described over 65 years ago, remains incompletely understood and inconsistently treated. We suspect that deficiencies in understanding its pathogenesis and fostering uniformity in its management could be remedied by teams working collaboratively to test the best ideas through multicentered trials. We begin this review by proposing a data-based definition of anemia, and of “severe” anemia, among infants at birth and during the neonatal period. We then review early as well as recent reports of the “late” anemia of HDFN, suggesting that two pathogenic forms of the condition exist; <em>hemolytic vs. non-hemolytic (hypoproductive)</em>. We then review the use of a noninvasive and rapid means of differentiating between these two possibilities, in any given case. Next, we review means of either preventing the “late” anemia or treating it without red blood cell transfusions, using erythropoietic stimulating agents (darbepoetin or erythropoietin). We present our preferred method, using darbepoetin, and explain what we see as the chief advantages. We call for the development of transfusion stewardship programs in each NICU, to establish NICU transfusion guidelines, periodically evaluate compliance, and provide advice for problem cases. In addition, these programs can endorse a consistent approach to managing neonates with HDFN, during their NICU stay and for the weeks after discharge. We end the review with a gap analysis and a call for new focused research aimed at producing better outcomes for these patients, and less uncertainty and stress for these families.</div></div>","PeriodicalId":50732,"journal":{"name":"Best Practice & Research Clinical Obstetrics & Gynaecology","volume":"102 ","pages":"Article 102650"},"PeriodicalIF":4.1,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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