Bjog-An International Journal of Obstetrics and Gynaecology最新文献

{"title":"Risk of Spontaneous Preterm Birth in a Subsequent Pregnancy After Full Dilatation Caesarean Birth: A Nationwide Cohort Study","authors":"Sara Acker,&nbsp;Catharina Hein Hoffmann,&nbsp;Lea Kirstine Hansen,&nbsp;Julie Glavind,&nbsp;Maria Jeppegaard,&nbsp;Lone Krebs","doi":"10.1111/1471-0528.18225","DOIUrl":"10.1111/1471-0528.18225","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate the association between caesarean birth in the second stage of labour and the risk of spontaneous preterm birth in a subsequent pregnancy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Nationwide register-based cohort study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>The Danish Medical Birth Registry and The Danish National Patient Register from 1997 to 2021.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Population</h3>\u0000 \u0000 <p>Women with at least two consecutive births (index birth and subsequent birth) where the index birth was a term singleton.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Women with spontaneous preterm subsequent birth were compared according to the mode of index birth, including vaginal, prelabour caesarean, first stage caesarean and second-stage caesarean.</p>\u0000 \u0000 <p>Statistical analysis was performed using multiple logistic regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measure</h3>\u0000 \u0000 <p>Spontaneous birth before 37 + 0 gestational weeks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 376 414 women met the inclusion criteria. Distribution of mode of index birth was vaginal 318 117 (84.5%), prelabour caesarean 15 373 (4.1%), first stage caesarean 37 547 (10.0%) and second-stage caesarean 5377 (1.4%), respectively. The rate of subsequent preterm birth was 1.7%. Compared to vaginal birth, a second-stage caesarean was associated with an increased risk of preterm birth in a subsequent pregnancy (adjusted odds ratio [aOR] 1.46, 95% confidence interval [CI] 1.21–1.77). Similarly, compared to first stage caesarean, a second-stage caesarean was associated with an increased risk of preterm birth in the subsequent pregnancy, with an aOR of 1.41 (95% CI 1.15–1.74).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Second-stage caesarean in a previous term pregnancy is associated with an increased risk of spontaneous preterm birth in a subsequent pregnancy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 11","pages":"1585-1593"},"PeriodicalIF":4.3,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1111/1471-0528.18225","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal Diagnosis of Foetal Structural Anomalies Using Medium-Coverage Whole Genome Sequencing (CMA-Seq): A Large-Scale Comparative Study With CMA in 3973 Pregnancies","authors":"Yan Jiang,&nbsp;Fang Liu,&nbsp;Lijuan Zhong,&nbsp;Rong Zhong,&nbsp;Mingxing Liang,&nbsp;Lin Ma,&nbsp;Victor Wei Zhang,&nbsp;Baixue Chen,&nbsp;Qian Zhang,&nbsp;Lei Xu,&nbsp;Wei Zhou","doi":"10.1111/1471-0528.18222","DOIUrl":"10.1111/1471-0528.18222","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the feasibility and effectiveness of medium-coverage whole genome sequencing (CMA-seq) for prenatal diagnosis of foetal structural anomalies, and to compare its performance with conventional chromosomal microarray analysis (CMA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>A prospective clinical study combined with a systematic meta-analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>A tertiary maternal and child health hospital in Chongqing, China.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Population or Sample</h3>\u0000 \u0000 <p>3973 pregnant women with ultrasound-detected foetal structural anomalies or other high-risk indications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Specimens were collected through amniocentesis, followed by CMA-seq to identify a wide range of chromosomal abnormalities. Meta-analysis was used to study the application and effectiveness of CMA in prenatal diagnosis. Clinical studies were screened in Chinese and English databases, and a meta-analysis was performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measures</h3>\u0000 \u0000 <p>Detection rates for chromosomal abnormalities, including mosaic aneuploidy, small copy number variants (CNVs &lt; 100 kb) and absence of heterozygosity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>CMA-seq identified chromosomal abnormalities in 24.72% (982/3973) of cases. Mosaic aneuploidy was detected in 6.5% of samples (42 cases &lt; 30% mosaicism). A total of 670 cases were presented with CNVs, including 40 below 100 kb. AOH was found in 112 cases (2.82%). The meta-analysis indicated a lower pooled chimeric chromosome detection rate (1.10%), a smaller proportion of CNVs &lt; 500 kb (2.06%), and reduced AOH detection (1.26%) with conventional CMA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>CMA-seq exhibits significant advancements and superior sensitivity in detecting low-level mosaic aneuploidy, small segment CNVs and AOH.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 10","pages":"1489-1501"},"PeriodicalIF":4.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of a Prediction Model for Adverse Perinatal Outcomes in Foetal Growth Restriction Based on a Machine Learning Algorithm: A Retrospective Study","authors":"Xiangli Meng,&nbsp;Lei Wang,&nbsp;Minghui Wu,&nbsp;Na Zhang,&nbsp;Xiaofei Li,&nbsp;Qingqing Wu","doi":"10.1111/1471-0528.18226","DOIUrl":"10.1111/1471-0528.18226","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To create and validate a machine learning (ML)-based model for predicting the adverse perinatal outcome (APO) in foetal growth restriction (FGR) at diagnosis.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Design&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A retrospective study.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Setting&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Multi-centre in China.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Population&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Pregnancies affected by FGR.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;We enrolled singleton foetuses with a perinatal diagnosis of FGR who were admitted between January 2021 and November 2023. A total of 361 pregnancies from Beijing Obstetrics and Gynecology Hospital were used as the training set and the internal test set. In comparison, data from 50 pregnancies from Haidian Maternal and Child Health Hospital were used as the external test set. Feature screening was performed using the random forest (RF), the Least Absolute Shrinkage and Selection Operator (LASSO) and logistic regression (LR). Subsequently, six ML methods, including Stacking, were used to construct models to predict the APO of FGR.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Main Outcome Measures&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Model's performance was evaluated through indicators such as the area under the receiver operating characteristic curve (AUROC). The Shapley Additive Explanation analysis was used to rank each model feature and explain the final model.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Mean ± SD gestational age at diagnosis was 32.3 ± 4.8 weeks in the absent APO group and 27.3 ± 3.7 in the present APO group. Women enrolled in the present APO group had a higher rate of hypertension related to pregnancy (74.8% vs. 18.8%, &lt;i&gt;p&lt;/i&gt; &lt; 0.001). Among 17 candidate predictors (including maternal characteristics, maternal comorbidities, obstetric characteristics and ultrasound parameters), the integration of RF, LASSO and LR methodologies identified maternal body mass index, hypertension, gestational age at diagnosis of FGR, estimated foetal weight (EFW) &lt;i&gt;z&lt;/i&gt; score, EFW growth velocity and abnormal umbilical artery Doppler (defined as a pulsatility index above the 95th percentile or instances of absent/reversed diastolic flow) as significant predictors. The Stacking model demonstrated a good performance in both the internal test set [AUROC: 0.861, 95% confidence interval (CI), 0.838–0.896] and the external test set [AUROC: 0.906, 95% CI, 0.875–0.947]. The calibratio","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 10","pages":"1514-1523"},"PeriodicalIF":4.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Predicting Preterm Birth: An Evolving Landscape”","authors":"","doi":"10.1111/1471-0528.18183","DOIUrl":"10.1111/1471-0528.18183","url":null,"abstract":"<p>\u0000 <span>Fox, C.</span> and <span>Shennan, A.</span> (<span>2025</span>), <span>Predicting Preterm Birth: An Evolving Landscape</span>. <i>BJOG</i>, <span>132</span>: <span>672</span>–<span>673</span>. https://doi.org/10.1111/1471-0528.18067\u0000 </p><p>We apologize for this error.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 8","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1471-0528.18183","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enabling Evaluation of Self-Care Post Pregnancy Hypertension","authors":"Abi Merriel","doi":"10.1111/1471-0528.18232","DOIUrl":"10.1111/1471-0528.18232","url":null,"abstract":"<p><b>Linked article:</b> This is a mini commentary on Mai et al., pp. 1350–1361 in this issue. To view this article, visit https://doi.org/10.1111/1471-0528.18152.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 10","pages":"1362-1363"},"PeriodicalIF":4.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caution Needed When Applying and Interpreting Causal Decompositions","authors":"Jeffrey N. Bone","doi":"10.1111/1471-0528.18231","DOIUrl":"10.1111/1471-0528.18231","url":null,"abstract":"<p><b>Linked article:</b> This is a mini commentary on Sasaki et al., pp. 1438–1451 in this issue. To view this article visit https://doi.org/10.1111/1471-0528.18153.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 10","pages":"1452-1453"},"PeriodicalIF":4.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144122383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stakeholder Perspectives on the Design of First-In-Human Trials for Artificial Amnion and Placenta Technology","authors":"Philip J. Steer","doi":"10.1111/1471-0528.18230","DOIUrl":"10.1111/1471-0528.18230","url":null,"abstract":"<p><b>Linked article</b>: This is a mini commentary on de Boer et al., pp. 1574–1583 in this issue. To view this article, visit https://doi.org/10.1111/1471-0528.18189</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 11","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy-Related Venous Thromboembolism Risk Perception and Prevention in Risk-Averse Times—Significant Change Required: a Commentary","authors":"Laura A. Magee,&nbsp;Roopen Arya,&nbsp;Clare Boag,&nbsp;Luci Buxton,&nbsp;Matthew A. Coleman,&nbsp;Fizzah Jivraj,&nbsp;Rebecca Scott,&nbsp;Kayleigh Sheen,&nbsp;Sergio A. Silverio,&nbsp;Peter von Dadelszen","doi":"10.1111/1471-0528.18229","DOIUrl":"10.1111/1471-0528.18229","url":null,"abstract":"<p>Between 2020 and 2022 in the United Kingdom (UK), there were 45 maternal deaths from venous thromboembolism (VTE), out of more than 2 million maternities. This occurred despite extensive risk assessment and prescribing of low molecular weight heparin (LMWH) thromboprophylaxis, alongside clinicians' overestimate of risk and commitment to the cause. Whilst every maternal death is a tragedy, the challenge ahead is immense—to identify, in an efficient and consistent way, those few women at risk of life-threatening thrombosis, and then minimise that risk with a cost-effective therapy that is acceptable to pregnant and postpartum women, and does not do more harm than good. We propose a way forward.</p>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 10","pages":"1341-1345"},"PeriodicalIF":4.3,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1471-0528.18229","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual Reality for Pain Management and Patient Satisfaction During Outpatient Hysteroscopy: A Randomised Controlled Trial","authors":"Alejandro Olloqui,&nbsp;Alvaro Tejerizo-Garcia,&nbsp;Carmen Guillen,&nbsp;Concha Perez-Sagaseta,&nbsp;Cristina Gonzalez-Macho,&nbsp;Ana Belen Bolívar-Miguel,&nbsp;Ana Villalba-Gutierrez,&nbsp;Blanca Gil-Ibañez","doi":"10.1111/1471-0528.18228","DOIUrl":"10.1111/1471-0528.18228","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate virtual reality (VR) as a distraction technique to diminish pain perception and improve satisfaction in patients who underwent an outpatient hysteroscopy (OH).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>A prospective, parallel group, 1:1 randomised controlled trial.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Spanish University Hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Sample</h3>\u0000 \u0000 <p>A total of 120 patients between 18 and 70 years old underwent an OH.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A total of 120 patients were randomly allocated to undergo an OH either with standard treatment with vocal-local support (<i>n</i> = 60) or with the use of a VR device (<i>n</i> = 60) between January and June 2022.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcome Measures</h3>\u0000 \u0000 <p>The primary outcome was worst and average patient-reported pain score (0–10) during the procedure. The secondary outcome was patient satisfaction (1–5) with the OH and with the use of VR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Mean duration of the procedure (4.57 vs. 5.63 min, <i>p</i> = 0.11) and procedure performed did not differ among groups. There were no statistically significant differences in worst pain perception (VAS score 4.83 vs. 4.84, <i>p</i> = 0.95) or average pain perception (VAS score 2.91 vs. 3.21, <i>p</i> = 0.41) between the standard care and the VR group. There were no statistically significant differences in patient satisfaction between both groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The use of VR was as effective as the standard care with vocal-local support to improve pain perception and patient satisfaction in patients undergoing OH.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov: NCT06463210</p>\u0000 </section>\u0000 </div>","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 10","pages":"1416-1425"},"PeriodicalIF":4.3,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is This Letter Truly Human-Written?","authors":"Shigeki Matsubara","doi":"10.1111/1471-0528.18227","DOIUrl":"10.1111/1471-0528.18227","url":null,"abstract":"","PeriodicalId":50729,"journal":{"name":"Bjog-An International Journal of Obstetrics and Gynaecology","volume":"132 10","pages":"1526-1527"},"PeriodicalIF":4.3,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144088041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}