Cancer Nursing最新文献

{"title":"Themes of Personal Becoming: An Exploration of Cancer Caregiver Narratives.","authors":"Charlotte R Weiss, Rachel Johnson-Koenke, Sean M Reed, Danny G Willis, Karen H Sousa","doi":"10.1097/NCC.0000000000001492","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001492","url":null,"abstract":"<p><strong>Background: </strong>The radical shift introduced by cancer can biographically rupture the life of the family caregiver (FCG). The life shift experienced by cancer FCGs calls for stories and storytelling to create meaning and make sense of how their lives can be reshaped and evolve despite the changes and ambiguity that cancer introduces to the family system.</p><p><strong>Objective: </strong>This study aimed to explore advanced cancer FCGs' experiences of personal becoming across the multifaceted dimensions of self.</p><p><strong>Methods: </strong>Grounded in unitary-transformative nursing science theories, we used narrative inquiry alongside photo elicitation to create and analyze 5 cancer caregiver narratives. Thematic narrative analysis was used to identify patterns related to personal becoming within and across the narratives.</p><p><strong>Results: </strong>The findings of personal becoming include multiple themes of transforming in ways of living and knowing: (1) past caring informs present caring of another and self, (2) meaning of life and purpose of self, (3) relationships with others, (4) relating to the natural world, (5) patterns of spiritual knowing, and (6) patterns of aesthetic knowing.</p><p><strong>Conclusions: </strong>The findings illustrate that cancer FCGs may incorporate new patterns of knowing, perceiving, and understanding themselves, others, and the natural world. Themes of personal becoming illuminate a greater understanding of the complex experience of caring in family relationships affected by advanced cancer.</p><p><strong>Implications for practice: </strong>Nurses have a vital role in actively engaging cancer FCGs in deriving meaning from their lived experiences of caring through stories and healing modalities that illuminate and facilitate their transformation of self.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Journey of Delayed Medical Consultation in Patients With Breast Cancer Who Have Giant Tumors.","authors":"Yi-Ping Weng, Shu-Chen Chen, Rei-Mei Hong, Wanyu Huang, Ying-Hsiang Wang, Yao-Hsu Yang, Hwey-Fang Liang","doi":"10.1097/NCC.0000000000001503","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001503","url":null,"abstract":"<p><strong>Background: </strong>Despite Taiwan's advanced healthcare system, many women delay seeking medical attention for breast abnormalities, leading to worsened health outcomes and increased medical costs.</p><p><strong>Objective: </strong>To explore the psychological journeys of patients with breast cancer who delayed medical consultation and presented with large tumors.</p><p><strong>Methods: </strong>A phenomenological qualitative study was conducted using purposive sampling and semistructured interviews with 12 participants. Giorgi's phenomenological method guided the data analysis.</p><p><strong>Results: </strong>Most participants (75%) were aged 50 or younger and had at least a high school education. Delays in seeking medical care ranged from 3 to 36 months, worsening disease severity, complicating treatment, and causing significant breast disfigurement. Four themes emerged from their journeys: being ignorant, inner turmoil, hesitation to move forward, and breaking through.</p><p><strong>Conclusions: </strong>Participants delayed care due to insufficient awareness, cognitive biases, emotional struggles, and reliance on self-treatment. Consequently, all participants were diagnosed at stage 3 or higher. Addressing barriers such as low health literacy, cultural stigmas, and limited access to care is essential to encourage early detection and timely medical consultation.</p><p><strong>Implications for practice: </strong>To prevent delays in seeking care, healthcare systems should enhance education on low awareness, cognitive biases, and self-treatment. Targeted interventions can empower women to recognize early symptoms and seek timely care. Healthcare professionals should be trained to address patients' fears and hesitations with empathetic, culturally sensitive communication. Reducing barriers, such as low health literacy, cultural stigmas, and limited access to care through community outreach and improved screening services, is essential for early detection and better outcomes.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Virtual Reality on Chemotherapy-Associated Stress (Cortisol Value), Anxiety, and Pain Symptoms of Mastectomy Patients: A Randomized Controlled Pilot Study.","authors":"Vesile Eskici İlgin, Ayşegül Yayla, Rümeysa L Toraman, Zeynep K Özlü, Tülay Kılınç, İbrahim Özlü","doi":"10.1097/NCC.0000000000001478","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001478","url":null,"abstract":"<p><strong>Background: </strong>Pain, anxiety, and stress are the most common symptoms experienced by patients receiving chemotherapy after breast surgery. Virtual reality (VR) can be used as a method to manage these symptoms.</p><p><strong>Objective: </strong>To determine the effect of VR on chemotherapy-associated stress (salivary cortisol value), anxiety, pain, and vital signs of mastectomy patients.</p><p><strong>Methods: </strong>A total of 62 participants were enrolled in this randomized, 2-group design. Participants in the experimental group watched videos with VR glasses during their chemotherapy treatments. Saliva samples were collected from participants in both the control and experimental groups before and immediately after their chemotherapy treatments. The Personal Information Form, state anxiety component of the State-Trait Anxiety Inventory, visual analog scale, and the patients' vital signs were also collected.</p><p><strong>Results: </strong>The State-Trait Anxiety Inventory state anxiety component and visual analog scale scores and the stress value mean scores differed significantly between the 2 groups at the second data point. There was also a statistically significant decrease in systolic blood pressure and diastolic blood pressure after chemotherapy in the experimental group.</p><p><strong>Conclusion: </strong>The use of VR in women receiving chemotherapy significantly reduced their pain, anxiety, stress and blood pressure from before to immediately following the chemotherapy infusion.</p><p><strong>Implications for practice: </strong>VR can be an appropriate intervention to reduce pain, anxiety, and stress in patients receiving chemotherapy after mastectomy.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Spiritual Well-being Among Oncology Nurses in Oman.","authors":"Fatema Al-Abdalii, Mohammad Al Qadire, Ahmad Musa, Omar Al Omari, Hanan Abdelrahman","doi":"10.1097/NCC.0000000000001500","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001500","url":null,"abstract":"<p><strong>Background: </strong>Spiritual care is a crucial component of oncology nursing, addressing patients' holistic needs. However, limited research has explored spiritual well-being, competence, practices, and barriers among oncology nurses, particularly within specific cultural and religious contexts.</p><p><strong>Objective: </strong>To assess spiritual well-being and its predictors, including perceived competence, practices, and barriers to providing spiritual care among oncology nurses in Oman.</p><p><strong>Methods: </strong>A descriptive correlational study was conducted with 422 oncology nurses from 3 cancer care centers in Muscat, Oman. Convenience sampling was used, and data were collected through validated instruments, including the Spiritual Well-being Scale, Spiritual Care Competence Scale, Nurse Spiritual Care Therapeutics Scale, and Spiritual Care Practice Questionnaire. SPSS version 27 was used for data analysis, using descriptive statistics, Pearson correlation, independent t tests, analysis of variance, and multiple linear regression.</p><p><strong>Results: </strong>Nurses exhibited high spiritual well-being (mean, 102.1 [SD, 14.7]) and moderate spiritual care competence (mean, 96.1 [SD, 19.1]), yet spiritual care practices were infrequent (mean, 37.6 [SD, 13.1]). Major barriers included beliefs about the privacy of patients' spirituality (59.5%) and lack of time (54.7%). Higher competence and prior oncology training were significantly associated with greater spiritual well-being.</p><p><strong>Conclusions: </strong>Although oncology nurses in Oman report high spiritual well-being, barriers such as time constraints and role perceptions hinder spiritual care practices.</p><p><strong>Implications for practice: </strong>Targeted education and training programs are essential to enhance spiritual care delivery. Addressing systemic challenges, including time management and role clarity, can foster a supportive environment for integrating spiritual care into oncology nursing.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prevalence and Factors of Dyspnea Among Advanced Cancer Survivors: A Systematic Review and Meta-analysis.","authors":"Tianxue Hou, Mu-Hsing Ho, Shumin Jia, Chia-Chin Lin","doi":"10.1097/NCC.0000000000001490","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001490","url":null,"abstract":"<p><strong>Background: </strong>Dyspnea is a significant symptom in advanced cancer patients, yet comprehensive evidence on its prevalence and related factors is lacking.</p><p><strong>Objective: </strong>This review aims to summarize the prevalence of dyspnea among advanced cancer survivors and identify associated factors.</p><p><strong>Methods: </strong>MEDLINE, EMBASE, Cochrane Library, PsycINFO, CINAHL Plus, and Web of Science were searched from inception to May 2024. Observational studies focusing on advanced cancer patients reporting dyspnea were included. Two reviewers performed data extraction and quality assessment independently using the Newcastle-Ottawa Scale. Prevalence estimates were pooled using a random-effects model. Subgroup analyses and metaregression were performed to explore heterogeneity.</p><p><strong>Results: </strong>A total of 67 studies involving 78 409 advanced cancer survivors were included, revealing a pooled prevalence of dyspnea of 43% (95% prediction interval, 0.07, 0.84). Significant variations were observed based on cancer types, with lung cancer showing a prevalence of 55%. Factors associated with dyspnea were categorized using the Breathing, Thinking, Functioning clinical model: (1) breathing: physical (eg, fatigue), medical (eg, lung disease), and treatment-related (eg, palliative sedation) factors; (2) thinking: psychological (eg, anxiety) factors; and (3) functioning: performance (eg, Karnofsky Performance Status) and demographic characteristics (eg, age).</p><p><strong>Conclusions: </strong>The findings highlight a high prevalence of dyspnea among advanced cancer survivors and identify several associated factors, stressing the need for early detection and comprehensive management strategies.</p><p><strong>Implications for practice: </strong>Health providers can improve the quality of life for patients by effectively managing dyspnea, thereby reducing symptom burden, and alleviating psychological distress, leading to better overall well-being for patients and caregivers.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sentinel and Networked Symptoms During Remission Induction Chemotherapy in Acute Lymphoblastic Leukemia Children.","authors":"Xinyi Shen, Jinling Ma, Yuying Chan, Rongrong Li","doi":"10.1097/NCC.0000000000001488","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001488","url":null,"abstract":"<p><strong>Background: </strong>Children with acute lymphoblastic leukemia experience various adverse symptoms during remission induction. Elucidating the interrelationships among symptoms can facilitate precise and efficacious symptom management.</p><p><strong>Objective: </strong>This study aimed to elucidate symptom clusters and sentinel symptoms and to examine core and bridge symptoms within the symptom network in children with acute lymphoblastic leukemia during remission induction.</p><p><strong>Methods: </strong>A cross-sectional survey of 226 children aged 8 to 16 years with a new diagnosis of acute lymphoblastic leukemia during remission induction chemotherapy was conducted using the Chinese version of the Memorial Symptom Assessment Scale 10-18. Symptom clusters and sentinel symptoms were identified using exploratory factor analysis and Apriori algorithm. Core and bridge symptoms were identified using network analysis.</p><p><strong>Results: </strong>Five symptom clusters and sentinel symptoms were identified: gastrointestinal (constipation as the sentinel symptom), emotional (feeling sad as the sentinel symptom), and somatic (cough as the sentinel symptom); however, the sentinel symptoms of neurological and self-image impairment symptom clusters were not specified. In symptom network, feeling sad and nausea were core symptoms, whereas dizziness and lack of energy were the bridge symptoms.</p><p><strong>Conclusions: </strong>The somatic symptom cluster should be prioritized for intervention during remission induction. Network analysis and sentinel symptom analysis must be extended to the symptom research in pediatric cancer to provide a scientific basis for symptom management.</p><p><strong>Implications for practice: </strong>Nurses should aim to identify and intervene with sentinel and networked symptoms to ensure that children are effectively supported during the remission induction, reducing symptom burden and improving quality of life.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Receiving Bad News by Telephone: The Lived Experience of Patients Undergoing the Diagnostic Workup for a Suspected Lung Cancer Diagnosis.","authors":"Ingrid C Andersen, Hanne Agerskov, Mette Kaasgaard, Charlotte Simonÿ, Uffe Bodtger","doi":"10.1097/NCC.0000000000001496","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001496","url":null,"abstract":"<p><strong>Background: </strong>Telecommunication (telephone, video) is increasingly being used in healthcare, including in the cancer area. Still, patients' lived experiences of receiving bad news over the telephone of first a suspected and later a confirmed cancer diagnosis remain sparsely researched.</p><p><strong>Objective: </strong>This study aimed to explore the lived experience of receiving results and plans by telephone in patients during an invasive workup for suspected lung cancer.</p><p><strong>Methods: </strong>Individual interviews were conducted with 11 patients 2 to 3 months after the final disclosure of cancer. Data were analyzed and interpreted within a phenomenological-hermeneutic framework.</p><p><strong>Results: </strong>When \"being on a journey from anticipation to the fact of the cancer diagnosis,\" patients appreciated being gently guided via ongoing information by telephone. However, some calls were confusing or inconvenient or did not involve desired relatives. When \"transferring toward the next step of treatment and care,\" patients felt warned and prepared for the planned disclosure of a cancer diagnosis by telephone.</p><p><strong>Conclusions: </strong>Using telephone communication during the diagnostic workup is well-suited to support patients during the vulnerable time of receiving a cancer diagnosis. To be effective, informing patients by telephone must involve a relational structure of anticipation, including a warning and personalized approach to help them and their relatives gradually realize the bad news.</p><p><strong>Implication for practice: </strong>This study contributes to the evidence base for breaking bad news via telecommunication. When connecting with patients remotely, an optimal procedure must be arranged so that matters of confidentiality, emotional concerns, and needs for involvement of relatives are explicitly ensured.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Red Cell Index and Depressive Symptoms in NHANES (2005-2018): A Cross-sectional Study.","authors":"Cheng Xing, Bowen Sui, Long He, Jing Yang, Zhendong Yang, Minghan Jiang, Weilong An","doi":"10.1097/NCC.0000000000001501","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001501","url":null,"abstract":"<p><strong>Background: </strong>Physical symptoms and emotional distress, such as melancholy, are common among cancer survivors. Misinterpreting these as normal reactions delays depression diagnosis and worsens prognosis. Patients may hide depressive symptoms during treatment, whereas clinicians and families often dismiss them as expected disease adaptation. Emerging evidence links depression to inflammatory responses and symptoms such as fatigue/cognitive decline to hypoxia, suggesting relevance of the Red Cell Index (RCI).</p><p><strong>Objective: </strong>To identify depression risk factors in cancer survivors and evaluate RCI as a potential biomarker.</p><p><strong>Methods: </strong>We included and analyzed 2890 patients from the National Health and Nutrition Examination Survey database in this study. The 9-item Patient Health Questionnaire was used to evaluate the depressive symptoms. We employed multivariable logistic regression and stratified analyses to evaluate the association between RCI and depressive symptoms.</p><p><strong>Results: </strong>Higher RCI inversely correlated with depression risk in unadjusted analysis, persisting after full adjustment. Subgroup findings were consistent. A significant nonlinear RCI-depression connection was found by dose-response analysis.</p><p><strong>Conclusions: </strong>As the RCI increased, the likelihood of depression in patients diagnosed with cancer decreased. Nevertheless, cross-sectional studies can merely establish the link, necessitating further research to validate causality and assess the practicality of clinical use.</p><p><strong>Implications for practice: </strong>Possible connections between hematological markers and depression symptoms are revealed by this investigation. The RCI-depression correlation offers new perspectives for nursing practice. For cancer survivor care, integrating validated hematological indicators into assessments alongside monitoring physical/psychological symptoms is recommended. Future research should prioritize RCI-depression risk assessment and early interventions in oncology patients.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Home-Based Exercise Program on Chemotherapy-Induced Peripheral Neuropathy and Quality of Life: A Single-blind Randomized Controlled Trial.","authors":"Necmiye Çömlekçi, Gülbeyaz Can, Faruk Taş","doi":"10.1097/NCC.0000000000001495","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001495","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent symptom that negatively affects quality of life. Exercise is a beneficial intervention for managing peripheral neuropathy; however, insufficient evidence remains in this regard.</p><p><strong>Objective: </strong>To evaluate the efficacy of a home-based exercise program in reducing the severity and symptoms of CIPN and improving quality of life.</p><p><strong>Methods: </strong>This randomized controlled trial included 72 participants (intervention: n = 37, control: n = 35), with data collected from September 2020 to August 2022. The intervention group followed a home-based exercise program twice daily for 8 weeks, whereas the control group received standard care. Peripheral neuropathy severity was measured using Common Terminology Criteria for Adverse Events, whereas symptoms and quality of life were assessed using the European Organization for Research and Treatment of Cancer Chemotherapy-Induced Peripheral Neuropathy Quality-of-Life Questionnaire and the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire.</p><p><strong>Results: </strong>Peripheral neuropathy symptom scores were significantly lower in the intervention group than in the control group at 8 weeks postintervention (P < .001). The effect size for sensory and motor neuropathy scores was large (d = 3.47 and d = 2.76, respectively). Quality-of-life scores were significantly higher in the intervention group than in the control group postintervention (P < .001), with a large effect size (η2 = 0.45).</p><p><strong>Conclusion: </strong>A home-based exercise program reduced the severity and symptoms of CIPN and improved quality of life.</p><p><strong>Implications for practice: </strong>A home-based exercise program with sensory, strengthening, and balance exercises can be integrated into patient care as a nursing practice to improve CIPN symptoms and quality of life.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frailty and Intrinsic Capacity as Predictors of Recovery in Older Patients Surgically Treated for Cancer: A Longitudinal Study.","authors":"Fang-Wen Hu, Chien-Yao Sun, Wu-Chou Su, Chia-Ming Chang","doi":"10.1097/NCC.0000000000001497","DOIUrl":"https://doi.org/10.1097/NCC.0000000000001497","url":null,"abstract":"<p><strong>Background: </strong>Advanced age, cancer, and surgery contribute to functional decline, with concurrent cancer and surgery exacerbating this decline due to slower recovery and adverse outcomes.</p><p><strong>Objective: </strong>To investigate the association between preoperative frailty and intrinsic capacity and postoperative functional recovery and quality of life in older patients surgically treated for cancer.</p><p><strong>Methods: </strong>This longitudinal study at a tertiary care medical center included 74 patients 75 years and older undergoing elective surgery for malignancies, excluding those with terminal-stage cancer. Data on demographic variables, Cumulative Illness Rating Scale for Geriatrics, Clinical Frailty Scale, and intrinsic capacity were collected at admission. The Minimum Data Set Activities of Daily Living (MDS-ADL) and EuroQoL 5-dimension 3-level questionnaire (EQ5D) were assessed at admission, after operation, and 1 month, 3 months, 6 months, and 1 year after the operation for cancer.</p><p><strong>Results: </strong>The mean age of the 74 participants was 80.3 ± 4.6 years, and 56.8% were female. The generalized estimating equation showed that an increased preoperative Clinical Frailty Scale score was significantly associated with worsened MDS-ADL (adjusted β = 1.25; 95% confidence interval = 0.39-2.11; P = .004) and decreased EQ5D score after surgery for cancer (adjusted β = -0.04; 95% confidence interval = -0.07 to -0.01; P = .004). No significant associations were observed between intrinsic capacity and postoperative MDS-ADL or EQ5D scores.</p><p><strong>Conclusion: </strong>This study demonstrated that frailty is a better predictor of postoperative functional recovery and quality of life than intrinsic capacity in older cancer patients.</p><p><strong>Implications for practice: </strong>Identifying frailty preoperatively can help healthcare providers better anticipate recovery challenges and tailor postsurgical care to improve outcomes.</p>","PeriodicalId":50713,"journal":{"name":"Cancer Nursing","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}