The Journal of nutrition最新文献_第2页

Inulin and oligofructose: proven health benefits and claims. Proceedings of the 5th ORAFTI Research Conference, September 28-29, 2006, Boston, Massachusetts. 菊粉和低聚果糖:已证实的健康益处和声明。第五届ORAFTI研究会议论文集，2006年9月28-29日，波士顿，马萨诸塞州。

IF 4.2

The Journal of nutrition Pub Date : 2007-11-01

引用次数: 0

Proceedings and abstracts of the International Research Conference on Food, Nutrition, and Cancer, July 13-14, 2006, Washington, DC, USA. 国际食品、营养与癌症研究会议论文集及摘要，2006年7月13-14日，华盛顿特区，美国。

IF 4.2

The Journal of nutrition Pub Date : 2007-01-01

引用次数: 0

Proceedings of the 5th Amino Acid Assessment Workshop. October 24-25, 2005. Los Angeles, California, USA. 第五届氨基酸评估研讨会论文集。2005年10月24日至25日。洛杉矶，加利福尼亚，美国。

IF 4.2

The Journal of nutrition Pub Date : 2006-06-01

引用次数: 0

Preclinical perspectives on garlic and cancer. 大蒜与癌症的临床前研究

IF 4.2

The Journal of nutrition Pub Date : 2006-03-01 DOI: 10.1093/jn/136.3.727S

John A Milner

{"title":"Preclinical perspectives on garlic and cancer.","authors":"John A Milner","doi":"10.1093/jn/136.3.727S","DOIUrl":"https://doi.org/10.1093/jn/136.3.727S","url":null,"abstract":"Evidence continues to point to the anticancer properties of fresh garlic extracts, aged garlic, garlic oil, and a number of specific organosulfur compounds generated by processing garlic. These anticarcinogenic and antitumorigenic characteristics appear to arise through both dose- and temporal-related changes in a number of cellular events involved with the cancer process, including those involving drug metabolism, immunocompetence, cell cycle regulation, apoptosis, and angiogenesis. The ability of garlic and related allyl sulfur compounds to block tumors in the colon, lung, breast, and liver suggests general mechanisms that are not tissue specific. Whereas relatively few studies have compared the relative efficacy of water- and lipid-soluble allyl sulfur compounds, those that have when using chemically induced carcinogen models suggest little difference in response, whereas tumor proliferation/apoptosis is highly dependent on the species provided. A shift in sulfhydryl groups, alterations in glutathione:oxidized glutathione ratios, and resultant changes in cellular redox status may be involved in some of the phenotypic changes caused by allyl sulfur compounds. Such changes in thiols by allyl sulfurs may also account for the observed hyperphosphorylation of specific cell cycle proteins and the histone hyperacetylation that has been correlated with suppressed tumor cell proliferation. Whereas the anticarcinogenic and antitumorigenic data to date are impressive, additional studies are needed with more modest exposure to allyl sulfur compounds over prolonged periods. Likewise, additional studies are needed that incorporate transgenic and knockout models to assist in the identification of molecular targets for garlic and its associated allyl sulfur components.","PeriodicalId":506898,"journal":{"name":"The Journal of nutrition","volume":" ","pages":"827S-831S"},"PeriodicalIF":4.2,"publicationDate":"2006-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/jn/136.3.727S","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25860840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 111

Proceedings of the 4th Amino Acid Assessment Workshop. October 28-29, 2004. Kobe, Japan. 第四届氨基酸评估研讨会论文集。2004年10月28日至29日。日本神户。

IF 4.2

The Journal of nutrition Pub Date : 2005-06-01

引用次数: 0

Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level. 健康个体的随意胆碱摄入量达到或超过建议的适当摄入量水平。

The Journal of nutrition Pub Date : 2005-04-01 DOI: 10.1093/jn/135.4.826

Leslie M Fischer, Julie A Scearce, Mei-Heng Mar, Jayanti R Patel, Renee T Blanchard, Beth A Macintosh, Marjorie G Busby, Steven H Zeisel

{"title":"Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level.","authors":"Leslie M Fischer, Julie A Scearce, Mei-Heng Mar, Jayanti R Patel, Renee T Blanchard, Beth A Macintosh, Marjorie G Busby, Steven H Zeisel","doi":"10.1093/jn/135.4.826","DOIUrl":"10.1093/jn/135.4.826","url":null,"abstract":"Choline is an essential nutrient for humans that is used to synthesize membrane phospholipids and the neurotransmitter acetylcholine. Betaine, a metabolite of choline, functions as a methyl-group donor in the conversion of homocysteine to methionine, and is important for renal function. Accurate analysis of choline intake was previously not possible because the choline content of most foods was not known. Using new and recently published data on the concentrations of choline in common foods, we measured the choline content of diets consumed ad libitum by healthy adult volunteers housed in a clinical research center and compared these with estimates of choline intake derived from 3-d food records kept by subjects immediately before study enrollment. Mean choline intake in this subject population met or slightly exceeded the current Adequate Intake (AI) of 7 mg/(kg . d) set by the Institute of Medicine. Men and women consumed similar amounts of choline per day (8.4 and. 6.7 mg/kg, respectively; P = 0.11). Choline intakes estimated from the 3-d food records were significantly lower than this (when expressed as mg/kg, or as total mg, but not when normalized to energy intake), suggesting underreporting of food intake. Intake of betaine, which may spare choline utilization as a methyl-group donor, was 5.3 mg/(kg . d) in men and 4.7 mg/(kg . d) in women. Intake of folate, vitamin B-12, and methionine + cysteine, were similar and sufficient in all subjects. The current recommended AI for choline seems to be a good approximation of the actual intake of this nutrient.","PeriodicalId":506898,"journal":{"name":"The Journal of nutrition","volume":" ","pages":"826-9"},"PeriodicalIF":0.0,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435379/pdf/nihms-50679.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25198361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proceedings and abstracts of the International Research Conference on Food, Nutrition, and Cancer. Washington, DC, USA, July 15-16, 2004. 国际食品、营养和癌症研究会议论文集和摘要。2004年7月15日至16日，美国华盛顿。

IF 4.2

The Journal of nutrition Pub Date : 2004-12-01

引用次数: 0

Arginine metabolism: enzymology, nutrition, and clinical significance. Proceedings of a symposium dedicated to the memory of Vernon R. Young. April 5-6, 2004. Bermuda. 精氨酸代谢:酶学、营养学和临床意义。纪念弗农·r·杨的研讨会论文集。2004年4月5日至6日。百慕大。

IF 4.2

The Journal of nutrition Pub Date : 2004-10-01

引用次数: 0

NUTRITION OF SALMONOID FISHES. XII. ISOLEUCINE, LEUCINE, VALINE AND PHENYLALANINE REQUIREMENTS OF CHINOOK SALMON AND INTER-RELATIONS BETWEEN ISOLEUCINE AND LEUCINE FOR GROWTH. 鲑科鱼类的营养。十二。奇努克鲑鱼生长对异亮氨酸、亮氨酸、缬氨酸和苯丙氨酸的需要量及异亮氨酸和亮氨酸的相互关系。

IF 4.2

The Journal of nutrition Pub Date : 1964-07-01