Cuaj-Canadian Urological Association Journal最新文献

{"title":"Canadian Urological Association-European Association of Urology 2025 Exchange.","authors":"Sender Herschorn","doi":"10.5489/cuaj.9310","DOIUrl":"10.5489/cuaj.9310","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":"19 8","pages":"E290-E293"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dispatches from productivity purgatory.","authors":"Michael Leveridge","doi":"10.5489/cuaj.9361","DOIUrl":"10.5489/cuaj.9361","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":"19 8","pages":"222-223"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hope in translation: Lessons from both sides of the bed.","authors":"Kennedy Dirk","doi":"10.5489/cuaj.9318","DOIUrl":"10.5489/cuaj.9318","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":"19 8","pages":"227"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Summary of changes in the 2025 Canadian Urological Association-Canadian Urologic Oncology Group guideline on metastatic castration-resistant prostate cancer.","authors":"Fred Saad, Alan I So","doi":"10.5489/cuaj.9359","DOIUrl":"10.5489/cuaj.9359","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":"19 8","pages":"228-229"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The natural history of prostate cancer.","authors":"Clare O'Connell, Rui M Bernardino, Neil E Fleshner","doi":"10.5489/cuaj.9117","DOIUrl":"10.5489/cuaj.9117","url":null,"abstract":"","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"275-281"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does marginalization status and distance from the hospital impact the timing of pediatric pyeloplasty in a universal access-to-care system?","authors":"Adree Khondker, Rahim Dhalla, David-Dan Nguyen, Jethro C C Kwong, Yerin Lee, Jeremy Wu, Jin Kyu Kim, Michael E Chua, Mandy Rickard, Armando J Lorenzo","doi":"10.5489/cuaj.9133","DOIUrl":"10.5489/cuaj.9133","url":null,"abstract":"<p><strong>Introduction: </strong>Prior research in the U.S. suggests that marginalized populations tend to undergo pyeloplasty earlier, likely reflecting concerns about the challenges of reliable followup care in this population. This study assessed the effect of sociodemographic marginalization and geographic distance on the timing of pyeloplasty in a universal, single-payer healthcare system.</p><p><strong>Methods: </strong>We performed a single-center, retrospective study on children undergoing pyeloplasty from 2008-2019. We assessed the impact of marginalization indices (with the Ontario Marginalization Index [ON-Marg]) and geographic distance on timing of pyeloplasty, preoperative ultrasound findings, and renogram features. Unadjusted analysis and Cox proportional regression were performed to determine the effect of marginalization and geography on timing of pyeloplasty.</p><p><strong>Results: </strong>Among 503 patients who underwent pyeloplasty, the median age at surgery was 16 months. Median preoperative anteroposterior diameter (APD) was 22 mm, and split renal function on renogram was 43%. There was no significant effect of marginalization indices on age at surgery. Patients living >50 km from the hospital had a later age at surgery than those living <10 km (p=0.04); however, there was no significant difference in preoperative APD or split function by marginalization index or geographic distance. Adjusted analyses revealed no significant associations between ON-Marg variables or geographic distance with age at surgery.</p><p><strong>Conclusions: </strong>In a universal healthcare system, marginalization status and geographic distance were not associated with the timing of pyeloplasty. These results contrast with literature from other settings and suggest that access to care can mitigate disparities in pediatric urology care.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"249-254"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity and health-related quality of life among men with prostate cancer living in remote areas of Quebec A cross-sectional, observational study.","authors":"Marie-Pierre Gendron, Abir El-Haouly","doi":"10.5489/cuaj.9077","DOIUrl":"10.5489/cuaj.9077","url":null,"abstract":"<p><strong>Introduction: </strong>The majority (97.5%) of men with prostate cancer (PCa) live for at least five years after diagnosis. The health-related quality of life (HRQoL) of such men is affected by the adverse effects of treatment. Men living in remote areas of Canada have difficulty accessing specialized medical resources and psychological support. This constitutes an additional burden that weighs heavily on their HRQoL. Regular physical activity (PA) has a direct benefit, or an effect mediated by emotional distress, on the HRQoL of such individuals. In Canada, and elsewhere in the world, there is a poor uptake of PA-related recommendations.</p><p><strong>Method: </strong>We conducted a cross-sectional, observational study among 85 participants between May 2023 and September 2023. We then explored, through mediation analyses, the association between PA and HRQoL, taking into account the potential mediating effect of emotional distress.</p><p><strong>Results: </strong>Most participants (61.2%) engaged in a high level of PA; however, their physical and mental HRQoL scores were low (mean scores of 41.99±6.09 and 52.40±4.86, respectively). Participants self-reported low levels of stress (mean score of 3.18±2.62). Very few participants (5.9%) displayed symptoms consistent with depression. In contrast, the majority of participants (92.9%) displayed symptoms of anxiety. No significant statistical association was observed between the level of PA and HRQoL.</p><p><strong>Conclusions: </strong>This lack of association may be explained by the short-term, seasonal nature of certain types of PA, which prevents such PA from having a positive effect on the HRQoL.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":"255-261"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of success and complications of monoplanar renal access for conventional prone percutaneous nephrolithotomy: Analysis of 662 cases.","authors":"Basheer N Elmohamady, Tamer Diab, Hosam Abdel Fattah Abu-Elnasr, Mahmoud Mobarak, Salah Elbashir, Amr S El-Dakhakhny, Rabea Omar, Adel El Fallah, Alaa El-Shaer, Yasser A Noureldin","doi":"10.5489/cuaj.9188","DOIUrl":"https://doi.org/10.5489/cuaj.9188","url":null,"abstract":"<p><strong>Introduction: </strong>Our aim was to assess how monoplanar fluoroscopy-guided access affects the outcomes of percutaneous nephrolithotomy (PCNL).</p><p><strong>Methods: </strong>This retrospective study included all patients who had renal stones and underwent prone PCNL using monoplanar fluoroscopy-guided access in a single tertiary care center between January 2015 and January 2024. Preoperative and postoperative patient- and procedure-related variables, such as operative time, intraoperative blood loss, number of tracts, complications, stone-free rate (SFR), and hospital stay, were assessed. Multivariable analysis was performed to detect predictors of residual stones and complications.</p><p><strong>Results: </strong>A total of 662 patients with an average age of 47±12 years were included. Comorbidities were reported in 26.1%. American Society of Anesthesiologists (ASA) score was 1 in 64.8%. The mean stone diameter was 2.8±0.9 cm. Only 6% had positive preoperative urine culture. The mean stone HU was 1054±304 with a mean operative time of 94±31 minutes. Most cases (74.9%) required only one tract. Postoperative fever was reported in 22.4%. The median estimated blood loss (EBL) was 160 mL. The complications included urine leak (4.1%), blood transfusion (1.5%), sepsis (1.5%), renal pelvic perforation (0.8%), superselective angio-embolization (0.6%), pleural injury (0.6%), and colonic injury (0.2%). The median hospital stay was three days. Approximately 73% were stone-free. The only predictor of residual stone was higher stone diameter (odds ratio [OR] 1.536, p=0.001). Predictors of complications were three tracts (OR 4.501, p=0.033) and higher EBL (OR 1.003, p<0.001).</p><p><strong>Conclusions: </strong>The monoplanar fluoroscopy-guided approach has demonstrated a noteworthy success rate, rendering it a safe modality for prone conventional PCNL.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of magnetic resonance imaging and targeted biopsy results in men with indwelling urinary catheters: A propensity score matched study.","authors":"Tomer Bashi, Adi Kidron, Ziv Savin, Amihay Nevo, Sophie Barnes, Ofer Yossepowitch, Roy Mano, Snir Dekalo","doi":"10.5489/cuaj.9194","DOIUrl":"https://doi.org/10.5489/cuaj.9194","url":null,"abstract":"<p><strong>Introduction: </strong>We sought to evaluate multiparametric magnetic resonance imaging (mpMRI) findings and biopsy results in men with an indwelling catheter undergoing prostate cancer screening. mpMRI is central to the evaluation of prostate cancer. Little is known as to the effect of an indwelling urinary catheter on prostate mpMRI findings and the results of subsequent biopsies.</p><p><strong>Methods: </strong>We retrospectively reviewed 5820 mpMRI exams performed from 2017-2023. Forty-eight patients underwent mpMRI with indwelling urinary catheter. Using propensity score matching, patients were matched 1:1 for age, pre-biopsy prostate-specific antigen (PSA), and prostate volume. Clinical characteristics, mpMRI findings, and targeted biopsy results were compared between the groups.</p><p><strong>Results: </strong>After propensity score matching, clinical characteristics of the study groups did not differ significantly. Prostate Imaging-Reporting & Data System (PI-RADS) distribution did not show a significant difference (p=0.51); PI-RADS ≥3 lesions were identified in 20/48 patients with indwelling catheters (42%) and in 18/50 patients without catheters (36%). Among patients with a PI-RADS score ≥3, clinically significant prostate cancer (CSPC) was identified in 5/20 patients carrying catheters and 6/18 patients without catheters (p=0.152). A higher rate of any cancer was identified in patients without a catheter (67% vs. 35%, p=0.049). PSA >9.79 ng/ml predicted the finding of CSPC in patients carrying urinary catheters with PI-RADS ≥3 lesions.</p><p><strong>Conclusions: </strong>Our findings suggest no significant difference in mpMRI findings and CSPC rates for patients with and without indwelling urinary catheters. Patients carrying urinary catheters suspected to harbor CSPC based on an elevated PSA level should undergo further evaluation, including mpMRI and biopsies when necessary before benign prostatic hyperplasia treatment.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of bladder cuff management on oncologic outcomes following radical nephroureterectomy for upper tract urothelial carcinoma: A systematic review and meta-analysis.","authors":"John Kim, Abdullah Alrumaih, Braden Millan, Michael Uy, Deron Britt, Jennifer Tang, Rahul Bansal","doi":"10.5489/cuaj.9145","DOIUrl":"https://doi.org/10.5489/cuaj.9145","url":null,"abstract":"<p><strong>Introduction: </strong>Bladder cuff excision (BCE) is an integral component of radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). While many approaches have been described, the optimal technique for BCE to provide maximal oncologic control remains unanswered. We aimed to perform a systematic review and meta-analysis to compare oncologic outcomes of different BCE techniques.</p><p><strong>Methods: </strong>The Ovid MEDLINE, Embase, CENTRAL, and Web of Science databases were searched for studies comparing oncologic outcomes of RNU for UTUC based on different BCE approaches. Techniques for BCE were categorized as intravesical, extravesical, or endoscopic. Our primary outcomes were intravesical recurrence rate (IVR) and intravesical recurrence-free survival (IVRFS). Secondary outcomes included recurrence-free survival (RFS) and cancer-specific survival (CSS). Meta-analysis was performed to compare the recurrence rates and survival outcomes associated with different BCE techniques.</p><p><strong>Results: </strong>Forty studies assessing a total of 17 168 patients were identified for inclusion. Open intravesical BCE was associated with superior univariate IVRFS (hazard ratio [HR] 1.27, 95% confidence interval [CI] 1.13-1.42, p=0.04, I²=43%), multivariate IVRFS (HR 1.44, 95% CI 1.16-1.80, p<0.0001, I²=75%), univariate RFS (HR 2.30, 95% CI 1.04-5.10, p=0.0002, I²=71%), and multivariate CSS (HR 1.62, 95% CI 1.22-2.15, p=0.33, I²=14%) when compared to non-intravesical techniques. Subgroup analysis revealed that this difference was primarily driven by the inferiority of the open extravesical approach. Endoscopic and non-endoscopic BCE demonstrated equivalent univariate and multivariate IVRFS, RFS, and CSS.</p><p><strong>Conclusions: </strong>Open intravesical BCE is associated with superior oncologic outcomes when compared to non-intravesical techniques. This difference is primarily driven by the open intravesical approach's superiority to the open extravesical approach. Endoscopic BCE showed equivalent outcomes when compared to non-endoscopic approaches. Prospective randomized trials can shed further light on the optimal approach to BCE.</p>","PeriodicalId":50613,"journal":{"name":"Cuaj-Canadian Urological Association Journal","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}