Medical Journal of Indonesia最新文献

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Bone growth evaluation in collagen-hydroxyapatite implant locations using digital radiography: an animal model 利用数字射线摄影评估胶原羟基磷灰石植入位置的骨生长：一种动物模型

Medical Journal of Indonesia Pub Date : 2024-02-05 DOI: 10.13181/mji.oa.237051

Laela Sari, Siti Julia, Lukmanda Evan Lubis, D. S. K. Sihono, Yessie Widya Sari, D. Soejoko

{"title":"Bone growth evaluation in collagen-hydroxyapatite implant locations using digital radiography: an animal model","authors":"Laela Sari, Siti Julia, Lukmanda Evan Lubis, D. S. K. Sihono, Yessie Widya Sari, D. Soejoko","doi":"10.13181/mji.oa.237051","DOIUrl":"https://doi.org/10.13181/mji.oa.237051","url":null,"abstract":"BACKGROUND Digital radiography has been used to evaluate the progress of bone growth with a collagen-hydroxyapatite implant in rabbit tibias. This study aimed to introduce digital radiography methods that provide comprehensive data availability for continuous information retrieval from the implant preparation to the cultivation period. \u0000METHODS 38 digital radiographs were divided into 3 treatment groups, namely a single defect without implant (control), single-implant, and three-implant. Radiographic acquisitions were performed at preparation time and post-implantation from 0 to 56 days. Observations were concentrated on the implantation site, followed by creating a lateral profile. The prediction of implantation growth was determined using relative bone density (RBD) percentage. \u0000RESULTS Based on the profile, the recovery process consisted of implant absorption and new bone tissue deposition. The absorption process was highly influenced by the defect size. In the control and single-implant groups, regardless of the different recovery processes, similar recovery results were observed 56 days post-implantation, with an RBD value of approximately 90%. Meanwhile, the three-implant group only had an RBD value of 62%. \u0000CONCLUSIONS Radiography can evaluate absorption and new bone growth during implantation in New Zealand white rabbits. Radiographs, which can be obtained at any time during cultivation, offered more information on the recovery implantation process than the other method that relies on data obtained after sacrificing the animals.","PeriodicalId":506124,"journal":{"name":"Medical Journal of Indonesia","volume":"14 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139804107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical risk factors of recurrent kidney stone disease: a cohort retrospective study in a tertiary referral hospital 复发性肾结石病的临床风险因素：一家三级转诊医院的队列回顾性研究

Medical Journal of Indonesia Pub Date : 2024-02-02 DOI: 10.13181/mji.oa.247166

W. Atmoko, Febriyani, Ary Indriana Savitri, Cuno Uiterwaal, Siti Setiati, Agus Rizal Ardy Hariandy Hamid, P. Birowo, N. Rasyid

{"title":"Clinical risk factors of recurrent kidney stone disease: a cohort retrospective study in a tertiary referral hospital","authors":"W. Atmoko, Febriyani, Ary Indriana Savitri, Cuno Uiterwaal, Siti Setiati, Agus Rizal Ardy Hariandy Hamid, P. Birowo, N. Rasyid","doi":"10.13181/mji.oa.247166","DOIUrl":"https://doi.org/10.13181/mji.oa.247166","url":null,"abstract":"BACKGROUND Nephrolithiasis or kidney stone disease (KSD) is common worldwide. Despite various effective treatment strategies, KSD recurrence remains a problem. This study aimed to investigate the risk factors of KSD recurrence. \u0000METHODS This retrospective cohort study used medical records of all patients who came to the Department of Urology, Cipto Mangunkusumo Hospital, Jakarta, from January 2014 to December 2019, with asymptomatic and symptomatic KSD. Demographic information, clinical data, exposure to risk factors, and recurrent KSD diagnosis were collected. Univariate and multivariate analyses using logistic regression were performed to determine the significant risk factors. \u0000RESULTS We reported 325 patients with a median age of 52 years. More than half of the patients were males and from Java. Staghorn stone dominated the KSD types found in 181 patients (55.7%). After undergoing percutaneous nephrolithotomy, 214 patients (65.8%) became stone-free. However, about 40.6% of them later developed recurrent KSD. The adjusted odds ratio in recurrent KSD were 1.46 (95% confidence interval [CI] 1.33–1.59) for younger age, 1.86 (95% CI 1.61–2.07) for overweight–obese, 2.13 (95% CI 1.89–2.31) for less fluid intake, 1.81 (95% CI 0.97–2.12) for routine tea consumption, 1.24 (95% CI 1.06–1.84) for routine vegetables consumption, 2.27 (95% CI 1.83–2.84) for a family history of KSD, and 2.08 (95% CI 1.77–2.39) for diabetes mellitus (DM). \u0000CONCLUSIONS Most patients with recurrent KSD were younger, overweight/obese, had less fluid intake, a family history of KSD, and DM. Modifying a healthy lifestyle and a balanced diet is important to prevent KSD recurrence.","PeriodicalId":506124,"journal":{"name":"Medical Journal of Indonesia","volume":"13 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139871213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical Journal of Indonesia Pub Date : 2024-02-02 DOI: 10.13181/mji.oa.247166

W. Atmoko, Febriyani, Ary Indriana Savitri, Cuno Uiterwaal, Siti Setiati, Agus Rizal Ardy Hariandy Hamid, P. Birowo, N. Rasyid

{"title":"Clinical risk factors of recurrent kidney stone disease: a cohort retrospective study in a tertiary referral hospital","authors":"W. Atmoko, Febriyani, Ary Indriana Savitri, Cuno Uiterwaal, Siti Setiati, Agus Rizal Ardy Hariandy Hamid, P. Birowo, N. Rasyid","doi":"10.13181/mji.oa.247166","DOIUrl":"https://doi.org/10.13181/mji.oa.247166","url":null,"abstract":"BACKGROUND Nephrolithiasis or kidney stone disease (KSD) is common worldwide. Despite various effective treatment strategies, KSD recurrence remains a problem. This study aimed to investigate the risk factors of KSD recurrence. \u0000METHODS This retrospective cohort study used medical records of all patients who came to the Department of Urology, Cipto Mangunkusumo Hospital, Jakarta, from January 2014 to December 2019, with asymptomatic and symptomatic KSD. Demographic information, clinical data, exposure to risk factors, and recurrent KSD diagnosis were collected. Univariate and multivariate analyses using logistic regression were performed to determine the significant risk factors. \u0000RESULTS We reported 325 patients with a median age of 52 years. More than half of the patients were males and from Java. Staghorn stone dominated the KSD types found in 181 patients (55.7%). After undergoing percutaneous nephrolithotomy, 214 patients (65.8%) became stone-free. However, about 40.6% of them later developed recurrent KSD. The adjusted odds ratio in recurrent KSD were 1.46 (95% confidence interval [CI] 1.33–1.59) for younger age, 1.86 (95% CI 1.61–2.07) for overweight–obese, 2.13 (95% CI 1.89–2.31) for less fluid intake, 1.81 (95% CI 0.97–2.12) for routine tea consumption, 1.24 (95% CI 1.06–1.84) for routine vegetables consumption, 2.27 (95% CI 1.83–2.84) for a family history of KSD, and 2.08 (95% CI 1.77–2.39) for diabetes mellitus (DM). \u0000CONCLUSIONS Most patients with recurrent KSD were younger, overweight/obese, had less fluid intake, a family history of KSD, and DM. Modifying a healthy lifestyle and a balanced diet is important to prevent KSD recurrence.","PeriodicalId":506124,"journal":{"name":"Medical Journal of Indonesia","volume":"10 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139811381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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