Jiahui Xu, Minghao Wang, Minyi Jin, Siyan Shang, Chuner Ni, Yili Hu, Xun Sun, Jun Xu, Bowen Ji, Le Li, Yuhua Cheng, Gaofeng Wang
{"title":"Flexible capacitive pressure sensor based on interdigital electrodes with porous microneedle arrays for physiological signal monitoring","authors":"Jiahui Xu, Minghao Wang, Minyi Jin, Siyan Shang, Chuner Ni, Yili Hu, Xun Sun, Jun Xu, Bowen Ji, Le Li, Yuhua Cheng, Gaofeng Wang","doi":"10.1063/10.0022174","DOIUrl":"https://doi.org/10.1063/10.0022174","url":null,"abstract":"Flexible pressure sensors have many potential applications in the monitoring of physiological signals because of their good biocompatibility and wearability. However, their relatively low sensitivity, linearity, and stability have hindered their large-scale commercial application. Herein, a flexible capacitive pressure sensor based on an interdigital electrode structure with two porous microneedle arrays (MNAs) is proposed. The porous substrate that constitutes the MNA is a mixed product of polydimethylsiloxane and NaHCO3. Due to its porous and interdigital structure, the maximum sensitivity (0.07 kPa−1) of a porous MNA-based pressure sensor was found to be seven times higher than that of an imporous MNA pressure sensor, and it was much greater than that of a flat pressure sensor without a porous MNA structure. Finite-element analysis showed that the interdigital MNA structure can greatly increase the strain and improve the sensitivity of the sensor. In addition, the porous MNA-based pressure sensor was found to have good stability over 1500 loading cycles as a result of its bilayer parylene-enhanced conductive electrode structure. Most importantly, it was found that the sensor could accurately monitor the motion of a finger, wrist joint, arm, face, abdomen, eye, and Adam’s apple. Furthermore, preliminary semantic recognition was achieved by monitoring the movement of the Adam’s apple. Finally, multiple pressure sensors were integrated into a 3 × 3 array to detect a spatial pressure distribution. Compared to the sensors reported in previous works, the interdigital electrode structure presented in this work improves sensitivity and stability by modifying the electrode layer rather than the dielectric layer.","PeriodicalId":506091,"journal":{"name":"Nanotechnology and Precision Engineering","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139255346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experiment on inducing apoptosis of melanoma cells by micro-plasma jet","authors":"Hua Li, Qihao Shi, Yanhua Yang, Jinghao Qi, Yuhan Zhang, Fengyun Wang, Xiaoxia Du, Wenxiang Xiao","doi":"10.1063/10.0022239","DOIUrl":"https://doi.org/10.1063/10.0022239","url":null,"abstract":"As a promising cancer treatment method, cold atmospheric plasma has received widespread attention in recent years. However, previous research has focused more on how to realize and expand the anti-cancer scope of plasma jet. There are also studies on the killing of small-scale cancer cells, but the effects of plasma jet on normal cells and normal cell clusters have been ignored. Therefore, we proposed a 50 µm sized micro-plasma jet device, and used the device to treat melanoma cells (A-375) and human glial cells (HA1800) to evaluate their anti-cancer effects and effects on normal cells. The experimental results show that this kind of micro-plasma jet device can effectively inactivate cancer cells in a short period of time, while having little effect on normal cells. This work provides a certain experimental basis for the application of fine plasma jet to clinically inactivate cancer cells.","PeriodicalId":506091,"journal":{"name":"Nanotechnology and Precision Engineering","volume":"64 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139272268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}