International Journal of Pathogen Research最新文献_第2页

Biochemical and Haematological Effects of Aqueous Leaf Extract of Sida cordifolia in Plasmodium beighei Infected Wistar Rats 西达虫草水叶提取物对受疟原虫感染的 Wistar 大鼠的生化和血液学影响

International Journal of Pathogen Research Pub Date : 2024-04-05 DOI: 10.9734/ijpr/2024/v13i3280

Ogwo Elisha Uko, Obioma Elizabeth Nweke, Okoye O. Fidelis, Ubani Clement Dimgba, Suleiman Ali Sani

{"title":"Biochemical and Haematological Effects of Aqueous Leaf Extract of Sida cordifolia in Plasmodium beighei Infected Wistar Rats","authors":"Ogwo Elisha Uko, Obioma Elizabeth Nweke, Okoye O. Fidelis, Ubani Clement Dimgba, Suleiman Ali Sani","doi":"10.9734/ijpr/2024/v13i3280","DOIUrl":"https://doi.org/10.9734/ijpr/2024/v13i3280","url":null,"abstract":"Assessment of haematological and biochemical parameters can be predictive of the adverse effects resulting from ingesting foreign substances. Thus, the aim of this study was to evaluate the biochemical and haematological indices in Plasmodium beighei infected wistar rats. Freshly harvested leaves of Sida cordifolia were washed and dried at room temperature, after which they were ground to fine powder and subsequently extracted. Twenty-five adult Wistar rats were divided into five groups of five rats each. Group I was the normal control and was administered 2 ml of distilled of water. Group II was infected without treatment, while Group III and IV were infected and afterwards administered 200 and 400 mg/kg of aqueous extract of Sida cordifolia respectively. Group V was administered the standard drug. Biochemical and haematological indices were determined using standard procedures. The Packed Cell Volume (PCV) reported for group II (negative) control was significantly (P<0.05) lower than that reported for the normal control. However, oral administration of 200 and 400 mg/kg of Sida cordifolia leaf extract significantly (P<0.05) increased it, though to a level which was significantly (P<0.05) lower than that reported for the normal control. Similar observation was made on Haemoglobin Concentration (Hb) and Red Blood Cell (RBC). However, a contrary observation was made on the white blood cell. Urea and creatinine reported for the negative control were significantly (P<0.05) higher than those reported for the normal control. However, the aforementioned parameters were significantly (P<0.05) reduced following oral administration of Sida cordifolia. In conclusion, it can be deduced from this study that Sida cordifolia leaf extract has the ability to restore distorted haematological and biochemical status resulting from P. berghei infection.","PeriodicalId":505811,"journal":{"name":"International Journal of Pathogen Research","volume":"18 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140739986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolation and Phenotypic Identification of some Molds Isolated from Peanut Pastes Sold in some Public Markets in the City of Daloa, Central-West, Côte d’Ivoire 从科特迪瓦中西部达洛亚市一些公共市场销售的花生酱中分离出的一些霉菌的分离和表型鉴定

International Journal of Pathogen Research Pub Date : 2024-04-04 DOI: 10.9734/ijpr/2024/v13i2279

Ouliedibou Noellie Guy-Rolande Glokpai, Constant Arthur Zébré, Krou Philippe Eba, K. C. Kouassi, K. Kouassi, Ibourahema Coulibaly

{"title":"Isolation and Phenotypic Identification of some Molds Isolated from Peanut Pastes Sold in some Public Markets in the City of Daloa, Central-West, Côte d’Ivoire","authors":"Ouliedibou Noellie Guy-Rolande Glokpai, Constant Arthur Zébré, Krou Philippe Eba, K. C. Kouassi, K. Kouassi, Ibourahema Coulibaly","doi":"10.9734/ijpr/2024/v13i2279","DOIUrl":"https://doi.org/10.9734/ijpr/2024/v13i2279","url":null,"abstract":"Molds are common contaminants in peanut pastes. Their presence can have a more or less serious effect on the health of the consumer. The general objective of this work is to evaluate the diversity of filamentous fungi producing mycotoxins in peanut paste sold in public markets in the city of Daloa. A total of fifty samples were collected from five markets for carrying out the work. Isolation was carried out on Sabouraud medium with chloramphenicol. An identification of filamentous fungi was carried out through the analysis of macroscopic and microscopic morphological characters. Of the 50 samples, ten do not contain mold with a rate of 20% and 40 contain mold with a rate of 80%. Macroscopic analysis after enumeration made it possible to identify two species of mold. These are Aspergillus niger and Aspergillus flavus. Microscopic examination made it possible to partially confirm its two species. The presence of these species with their mycotoxin production capacities suggests that contaminated peanut paste represents a risk to the health of consumers.","PeriodicalId":505811,"journal":{"name":"International Journal of Pathogen Research","volume":"15 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140741500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging Parasites among Apparently Healthy School Aged Children in Adamawa State, Nigeria 尼日利亚阿达马瓦州表面健康的学龄儿童中新出现的寄生虫

International Journal of Pathogen Research Pub Date : 2024-02-03 DOI: 10.9734/ijpr/2024/v13i1273

Filgona J., Hamawa S. S.

{"title":"Emerging Parasites among Apparently Healthy School Aged Children in Adamawa State, Nigeria","authors":"Filgona J., Hamawa S. S.","doi":"10.9734/ijpr/2024/v13i1273","DOIUrl":"https://doi.org/10.9734/ijpr/2024/v13i1273","url":null,"abstract":"Aim: This study examines the prevalence of Fasciola hepatica, Paragonimus westermani and Schistosoma intercalatum among school aged children across the geopolitical zones in Adamawa state, Nigeria. \u0000Study Design: A cross sectional study designed was used and the study was conducted between October 2019 – March 2020. The study population include school age children studying between 7 – 25 years, studying in government schools across the geopolitical zones in Adamawa state. \u0000Methods: A total of 1500 primary and secondary school students from 15 local government areas were enrolled for this study, residual stool samples were collected from each participant and immediately preserved in 10% formalin before taking to the laboratory where it is processed using concentration techniques and observed under the microscope. \u0000Results: A total of 0.80% % of the children were found to be positive for at least one of the three parasites, with Fasciola hepatica being the most prevalent 0.47%, followed by Schistosoma intercalatum 0.27% and Paragonomus westermani 0.07%. High prevalence of these emerging parasites was observed in the southern senatorial zone than central and none was reported from northern zone. \u0000Conclusion: This study reported for the presence Paragonimus westermani and Schistosoma intercalatum for the first time in Adamawa state, highlighting the need for further and a robust study to unravel the epidemiology of these parasites as well as other helminths associated with human infection in the state. This is critical for the design of intervention strategies.","PeriodicalId":505811,"journal":{"name":"International Journal of Pathogen Research","volume":"23 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139867879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Sweet Potato (Ipomoea batatas) for Early Blast Disease (Alternaria solani) 对甘薯（Ipomoea batatas）早疫病（Alternaria solani）的评估

International Journal of Pathogen Research Pub Date : 2024-02-03 DOI: 10.9734/ijpr/2024/v13i1272

M. J. Falade, G. O. Agbowuro

{"title":"Evaluation of Sweet Potato (Ipomoea batatas) for Early Blast Disease (Alternaria solani)","authors":"M. J. Falade, G. O. Agbowuro","doi":"10.9734/ijpr/2024/v13i1272","DOIUrl":"https://doi.org/10.9734/ijpr/2024/v13i1272","url":null,"abstract":"Aims: Early blight disease (Alternaria solani) is one of the main biotic factors limiting sweet potato production in the tropics. A multi-locational research was carried out to screen and identified sweet potato accessions that are resistant to the disease. \u0000Methodology: 21 sweet potato accessions were collected from different agro-ecological zones of Nigeria and screen against Alternaria solani by artificial inoculation of the pathogen in three diverse agro-ecological conditions. The accessions were named against their place of condition. The research were laid out in a Randomized Complete Block Design (RCBD) with three replications. Data were collected on days to 50% flowering, fresh root weight per plant, number of root per plant, number of main branches per plant, and above ground fresh biomass yield per plant at 15 weeks after planting (WAP). Disease scoring was done using rating scale 0f 0-9 and analyzed with IRRI STAR software. \u0000Results: The result revealed that there are variations in the 21 accessions studied. Offa performed best across the three environments followed by Umudike while Ado-Ekiti had the least performance in term of root yield. The screening shows that none of the 21 accessions is highly resistant. Four of the accessions were resistant, six accessions were moderately resistant, four accessions were susceptible, and three accessions were moderately susceptible while 4 accessions were highly susceptible to the pathogen. \u0000Conclusion: The findings concluded that the resistant accessions that gave high number roots could be used as a gene pool for Alternaria solani resistance breeding for cultivar improvement. The use of the identified resistant accessions with high root yield by farmers is encouraged pending the time commercial Alternaria solani resistant cultivars will be readily available and accessible.","PeriodicalId":505811,"journal":{"name":"International Journal of Pathogen Research","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139867782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging Parasites among Apparently Healthy School Aged Children in Adamawa State, Nigeria 尼日利亚阿达马瓦州表面健康的学龄儿童中新出现的寄生虫

International Journal of Pathogen Research Pub Date : 2024-02-03 DOI: 10.9734/ijpr/2024/v13i1273

Filgona J., Hamawa S. S.

{"title":"Emerging Parasites among Apparently Healthy School Aged Children in Adamawa State, Nigeria","authors":"Filgona J., Hamawa S. S.","doi":"10.9734/ijpr/2024/v13i1273","DOIUrl":"https://doi.org/10.9734/ijpr/2024/v13i1273","url":null,"abstract":"Aim: This study examines the prevalence of Fasciola hepatica, Paragonimus westermani and Schistosoma intercalatum among school aged children across the geopolitical zones in Adamawa state, Nigeria. \u0000Study Design: A cross sectional study designed was used and the study was conducted between October 2019 – March 2020. The study population include school age children studying between 7 – 25 years, studying in government schools across the geopolitical zones in Adamawa state. \u0000Methods: A total of 1500 primary and secondary school students from 15 local government areas were enrolled for this study, residual stool samples were collected from each participant and immediately preserved in 10% formalin before taking to the laboratory where it is processed using concentration techniques and observed under the microscope. \u0000Results: A total of 0.80% % of the children were found to be positive for at least one of the three parasites, with Fasciola hepatica being the most prevalent 0.47%, followed by Schistosoma intercalatum 0.27% and Paragonomus westermani 0.07%. High prevalence of these emerging parasites was observed in the southern senatorial zone than central and none was reported from northern zone. \u0000Conclusion: This study reported for the presence Paragonimus westermani and Schistosoma intercalatum for the first time in Adamawa state, highlighting the need for further and a robust study to unravel the epidemiology of these parasites as well as other helminths associated with human infection in the state. This is critical for the design of intervention strategies.","PeriodicalId":505811,"journal":{"name":"International Journal of Pathogen Research","volume":"115 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139808180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Sweet Potato (Ipomoea batatas) for Early Blast Disease (Alternaria solani) 对甘薯（Ipomoea batatas）早疫病（Alternaria solani）的评估

International Journal of Pathogen Research Pub Date : 2024-02-03 DOI: 10.9734/ijpr/2024/v13i1272

M. J. Falade, G. O. Agbowuro

{"title":"Evaluation of Sweet Potato (Ipomoea batatas) for Early Blast Disease (Alternaria solani)","authors":"M. J. Falade, G. O. Agbowuro","doi":"10.9734/ijpr/2024/v13i1272","DOIUrl":"https://doi.org/10.9734/ijpr/2024/v13i1272","url":null,"abstract":"Aims: Early blight disease (Alternaria solani) is one of the main biotic factors limiting sweet potato production in the tropics. A multi-locational research was carried out to screen and identified sweet potato accessions that are resistant to the disease. \u0000Methodology: 21 sweet potato accessions were collected from different agro-ecological zones of Nigeria and screen against Alternaria solani by artificial inoculation of the pathogen in three diverse agro-ecological conditions. The accessions were named against their place of condition. The research were laid out in a Randomized Complete Block Design (RCBD) with three replications. Data were collected on days to 50% flowering, fresh root weight per plant, number of root per plant, number of main branches per plant, and above ground fresh biomass yield per plant at 15 weeks after planting (WAP). Disease scoring was done using rating scale 0f 0-9 and analyzed with IRRI STAR software. \u0000Results: The result revealed that there are variations in the 21 accessions studied. Offa performed best across the three environments followed by Umudike while Ado-Ekiti had the least performance in term of root yield. The screening shows that none of the 21 accessions is highly resistant. Four of the accessions were resistant, six accessions were moderately resistant, four accessions were susceptible, and three accessions were moderately susceptible while 4 accessions were highly susceptible to the pathogen. \u0000Conclusion: The findings concluded that the resistant accessions that gave high number roots could be used as a gene pool for Alternaria solani resistance breeding for cultivar improvement. The use of the identified resistant accessions with high root yield by farmers is encouraged pending the time commercial Alternaria solani resistant cultivars will be readily available and accessible.","PeriodicalId":505811,"journal":{"name":"International Journal of Pathogen Research","volume":"645 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139807491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emergency Microscope Light Modification by External Source in Absence of Power Supply 在没有电源的情况下利用外部光源改变应急显微镜的光线

International Journal of Pathogen Research Pub Date : 2024-01-04 DOI: 10.9734/ijpr/2024/v13i1268

F. E. Siagian

{"title":"Emergency Microscope Light Modification by External Source in Absence of Power Supply","authors":"F. E. Siagian","doi":"10.9734/ijpr/2024/v13i1268","DOIUrl":"https://doi.org/10.9734/ijpr/2024/v13i1268","url":null,"abstract":"Introduction: Microscope is an instrument for visualizing fine detail of an object so that observer can observe the object being examined in detail. The object of examination vary from cells (normal or pathologic), microorganism (such as parasite and bacterium), and even non biological part. There are several types of microscope, one of the oldest forms and still used today is the light microscope. A light microscope relied on continuous light source to operate. The most common source for today's microscopes is an incandescent tungsten-halogen bulb, which is solely electric dependent, positioned in a reflective housing that projects light through the collector lens and into the sub-stage condenser. Current situations sometimes require readiness for conducting microscopic examination anytime, anywhere. Unfortunately, problem occur if the electricity goes out, most people will not be able to continue their microscopic observations. This problem raises the question of what if in an emergency it is necessary to carry out a microscopic examination but unfortunately there is no power source. Below we propose emergency modification efforts so that the microscope can still be used even in conditions without a power source. \u0000Aims: to modify an electric light microscope in such a way that it can continue to be used in the absence of an electrical power source using external source of light. \u0000Discussion: Adding an external source of light is a brilliant approach in order to make the electric dependent light microscope still useable in emergency condition. \u0000Conclusion: it is possible to modify an electric light microscope in the condition of no electric source available and make it operable.","PeriodicalId":505811,"journal":{"name":"International Journal of Pathogen Research","volume":"20 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139386428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0