Clinical Journal of Obstetrics and Gynecology最新文献_第2页

Thyroid Cancer and Quality of Life: A Literature Review 甲状腺癌与生活质量：文献综述

Clinical Journal of Obstetrics and Gynecology Pub Date : 2024-02-05 DOI: 10.29328/journal.cjog.1001156

Soares Luísa, Gomes Karina, dos Santos Silva Inês

引用次数: 0

Thyroid Cancer and Quality of Life: A Literature Review 甲状腺癌与生活质量：文献综述

Clinical Journal of Obstetrics and Gynecology Pub Date : 2024-02-05 DOI: 10.29328/journal.cjog.1001156

Soares Luísa, Gomes Karina, dos Santos Silva Inês

引用次数: 0

Antioxidants and Pregnancy Complications: Exploring Therapeutic Strategies for Better Outcomes 抗氧化剂与妊娠并发症：探索治疗策略，提高疗效

Clinical Journal of Obstetrics and Gynecology Pub Date : 2024-01-25 DOI: 10.29328/journal.cjog.1001155

Obeagu Emmanuel Ifeanyi

{"title":"Antioxidants and Pregnancy Complications: Exploring Therapeutic Strategies for Better Outcomes","authors":"Obeagu Emmanuel Ifeanyi","doi":"10.29328/journal.cjog.1001155","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001155","url":null,"abstract":"Pregnancy complications present significant challenges, impacting maternal health and fetal development. Oxidative stress, a key contributor to various pregnancy-related disorders such as preeclampsia, gestational diabetes mellitus (GDM), and preterm birth, has spurred interest in exploring antioxidant interventions. Antioxidants, known for their ability to counteract oxidative damage, have emerged as potential therapeutic agents to mitigate these complications. This paper synthesizes current knowledge on the role of antioxidants in pregnancy, elucidating their mechanisms of action, sources, and impact on oxidative stress-related complications. It examines diverse antioxidant compounds, including vitamins C and E, selenium, and natural phytochemicals, highlighting their potential to modulate oxidative stress pathways and promote maternal-fetal well-being. Furthermore, this paper critically analyzes clinical studies, meta-analyses, and preclinical research exploring the efficacy and safety of antioxidant supplementation during pregnancy. It discusses the complexities surrounding optimal dosages, timing, and formulations of antioxidants, aiming to delineate strategies for their integration into prenatal care. In conclusion, this review provides insights into the promising role of antioxidants as therapeutic strategies to alleviate pregnancy complications associated with oxidative stress. It highlights avenues for future research, advocating for a deeper understanding of antioxidant mechanisms and their optimal utilization in prenatal care to enhance maternal and fetal health outcomes.","PeriodicalId":505668,"journal":{"name":"Clinical Journal of Obstetrics and Gynecology","volume":"82 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140496059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rejuvenation of Ovarian Function after Autologous Platelet Lysate Injection: Promising Evidence from Confirmed Cases 自体血小板溶胞浆注射后卵巢功能恢复：来自确诊病例的有力证据

Clinical Journal of Obstetrics and Gynecology Pub Date : 2023-12-13 DOI: 10.29328/journal.cjog.1001153

Garavelas Athanasios, Michalopoulos Efstathios, Mallis Panagiotis, Nikitos Eros

{"title":"Rejuvenation of Ovarian Function after Autologous Platelet Lysate Injection: Promising Evidence from Confirmed Cases","authors":"Garavelas Athanasios, Michalopoulos Efstathios, Mallis Panagiotis, Nikitos Eros","doi":"10.29328/journal.cjog.1001153","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001153","url":null,"abstract":"Intraovarian injection of autologous Platelet Lysate (PL) can be considered a potential therapeutic strategy for ovarian function rejuvenation. Especially, in women diagnosed with Poor Ovarian Response (POR) or Primary Ovarian Insufficiency (POI), the exogenous administration of the autologous platelet-derived growth factors, influence positively the regulation of the serum Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), and Anti-Mullerian Hormone (AMH) and Estradiol (E2). Therefore, the evaluation of the serum levels of the aforementioned hormones was performed on 10 participants with a mean age of 43 ± 4 years diagnosed with POR or POI, who received intraovarian PL injection monotherapy. The monitoring of the serum hormone levels was performed for 3 months. The results of this study clearly showed that all participants were characterized by elevated levels of FSH and LH and reduced levels of E2 and AMH, prior to the PL injection. However, the levels of all hormones started to change after the 1st month of follow-up monitoring. Moreover, 40% of the participants conceived successfully either by natural way or after in vitro Fertilization (IVF). Considering these, the intraovarian injection of autologous PL exhibited promising evidence regarding the altering of hormone levels at physiological values. Moreover, the contained PL growth factors were implicated in angiogenesis promotion and also in toleration of the inflammatory microenvironment, regulating positively ovarian function. In conclusion, the intraovarian autologous PL injection is considered a safe, effective, and tolerable therapeutic strategy in women with POR or POI. Moreover, the results of this study were very encouraging, especially for the women with infertility issues, who want their genetic offspring.","PeriodicalId":505668,"journal":{"name":"Clinical Journal of Obstetrics and Gynecology","volume":"187 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139181313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of In vitro and Ex vivo Models for Studying the Effectiveness of Vaginal Drug Systems in Controlling Microbe Infections: A Systematic Review 评估用于研究阴道药物系统控制微生物感染效果的体外和体内模型：系统回顾

Clinical Journal of Obstetrics and Gynecology Pub Date : 2023-11-28 DOI: 10.29328/journal.cjog.1001151

Karami Mohammad Hossein, Abdouss Majid, Karami Mandana

{"title":"Evaluation of In vitro and Ex vivo Models for Studying the Effectiveness of Vaginal Drug Systems in Controlling Microbe Infections: A Systematic Review","authors":"Karami Mohammad Hossein, Abdouss Majid, Karami Mandana","doi":"10.29328/journal.cjog.1001151","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001151","url":null,"abstract":"The survey gives an in-depth examination of medicate assimilation challenges within the genital range and the improvement of vaginal medicate conveyance gadgets to overcome these challenges. It investigates the components involved in medicate discharge within the genital locale and examines commonly utilized vaginal sedate conveyance frameworks such as nanoparticles and hydrogels. The survey centers on the applications of these conveyance frameworks in controlling bacterial vaginal diseases. The plan issues related to vaginal sedate conveyance gadgets are moreover examined, highlighting the significance of considering variables such as mucoadhesion and bodily fluid porousness. The survey portrays different in vitro and ex vivo models utilized for assessing these frameworks, counting organoids and new human cervical bodily fluid. The choice of show depends on the particular objectives and characteristics of the definition. The audit emphasizes the noteworthiness of utilizing these models to pick up important bits of knowledge and make precise forecasts with respect to the execution of medicate conveyance frameworks in vivo. Moreover, grandstands progressed models utilized for other mucosal locales as a potential motivation for future models of the female regenerative framework. Generally, the audit highlights the significance of understanding organic instruments and planning compelling vaginal drug conveyance frameworks to progress sedate conveyance within the genital region. It emphasizes the require for suitable models to evaluate and anticipate the execution of these conveyance frameworks.","PeriodicalId":505668,"journal":{"name":"Clinical Journal of Obstetrics and Gynecology","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139221052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Women's Perceptions of Medical Treatment Versus Surgical Management of First-trimester Miscarriage 妇女对初产妇流产的药物治疗与手术治疗的看法

Clinical Journal of Obstetrics and Gynecology Pub Date : 2023-11-27 DOI: 10.29328/journal.cjog.1001150

Elzein Azza Mustafa, Ahmed Hajar Suliman Ibrahim, Suliman Awadalla Abdelwahid, Handay Siddig Omer M, Omer Gamar Bushra, Musa Sahar Ali

{"title":"Women's Perceptions of Medical Treatment Versus Surgical Management of First-trimester Miscarriage","authors":"Elzein Azza Mustafa, Ahmed Hajar Suliman Ibrahim, Suliman Awadalla Abdelwahid, Handay Siddig Omer M, Omer Gamar Bushra, Musa Sahar Ali","doi":"10.29328/journal.cjog.1001150","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001150","url":null,"abstract":"Background: Miscarriage is a common gynecological problem and early pregnancy loss occurs in the first trimester. Early pregnancy miscarriage is managed expectantly, surgically, and medically. Medical management is a new treatment option, also surgical evacuation is the standard treatment for some types and presentations of miscarriage. Medical management might be more suitable instead of surgical evacuation, it may be less costly than surgical treatment and consequently, due to its lower complications, most patients prefer it. Purpose: This study aimed to determine women's perception of medical treatment versus surgical intervention, complications associated with surgical procedures, and medical treatment. Methodology: It was a comparative, hospital-based study conducted in Bashair Teaching Hospital, on 336 patients diagnosed with miscarriage in the first trimester, 168(group A) were treated medically while 168(group B) were treated surgically. All participating patients in the study fulfilled the selection criteria, that is, the provision of an informed consent and agreement to participate in the study. Results: The total number of women during the period of study was 336. The study found that 239(71%) of women prefer medical management compared to 97 (29%) preferring surgery. The complications associated with the medical treatment were (4.2%) infection, (0.6%) bleeding, and (95.2%) without obvious complications. The complications associated with surgical procedures were (7.7%) developmental infection, (16.1%) bleeding, (10.7%) incomplete evacuation, (1.8%) uterine perforation, and (63.7%) without obvious complications. Conclusion: The study found that over two-thirds of patients Favor medical treatment over surgical procedures. It has also revealed that medical treatment is very effective in terminating pregnancies within the first trimester.","PeriodicalId":505668,"journal":{"name":"Clinical Journal of Obstetrics and Gynecology","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139230480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Near-miss Women Causes and Prevalence in Alobied Maternity Hospital 阿洛伊比德妇产医院妇女近失事故的原因和发生率

Clinical Journal of Obstetrics and Gynecology Pub Date : 2023-11-13 DOI: 10.29328/journal.cjog.1001149

Eltigani Ayat, Ahmed Taha Umbeli, Suliman Awadalla Abdelwahid, SalahEldin Abdelsalam, Siralkatim Isra, Suliman Hajar

{"title":"Near-miss Women Causes and Prevalence in Alobied Maternity Hospital","authors":"Eltigani Ayat, Ahmed Taha Umbeli, Suliman Awadalla Abdelwahid, SalahEldin Abdelsalam, Siralkatim Isra, Suliman Hajar","doi":"10.29328/journal.cjog.1001149","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001149","url":null,"abstract":"Background: Maternal near-miss (MNM) events occur more frequently than maternal deaths; therefore, more detailed and comprehensive studies on maternal morbidity have been conducted and are of value to clinical audits and practices. Purpose: This study aimed to determine the frequency of maternal near misses and the nature of near-missevents. Methodology: This descriptive, retrospective, cross-sectional study over 12 months duration was conducted at the Alobied Teaching Hospital in 2018. Data were collected from patient notes, partographs, and other relevant documents. Demographic and clinical data concerning personal history, obstetric history, and near-miss events. Results: A total of 15202 women were admitted, 339 cases of maternal near misses, maternal near-missrate (MNMR) of 22.3|1000 live births, 200(59%) had an infection, 80(23.6%) hemorrhage, 20(5.9%) severe pre-eclampsia,12(3.5%) eclampsia, 20(5.9%) anemia, convulsions 5 (1.5%) 17(5%) of the cases were admitted to intensive care unit (ICU), 9(2.7%) had liver dysfunction, 9(2.7%) coagulation dysfunction, 8(2.4%) renal dysfunction, 5(1.5%) cerebral problems, 4(1.2%) cardiac dysfunction, and 2(0.6%) had developed respiratory dysfunction. Conclusion: The maternal near-miss rate was 22.3|1000 live births. Most near-miss cases occurred before the women arrived at the hospital. The major causes of maternal near misses were infection, hemorrhage anemia, pre-eclampsia, and eclampsia.","PeriodicalId":505668,"journal":{"name":"Clinical Journal of Obstetrics and Gynecology","volume":"83 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139278863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effectiveness of Honey-Based Ferric Perchloride Paste on Post-conization in the Cicatricial and Infectious Context: A Randomized Clinical Trial 蜂蜜盐酸铁膏对溃疡性和感染性溃疡后结痂的疗效：随机临床试验

Clinical Journal of Obstetrics and Gynecology Pub Date : 2023-11-07 DOI: 10.29328/journal.cjog.1001148

Maestri Carlos Afonso, Antoniazzi Rodolfo Belz, Maestri Isabela Ceschin, Fernandes Rafaela Ceschin, Fonseca Fernanda Villar

{"title":"The Effectiveness of Honey-Based Ferric Perchloride Paste on Post-conization in the Cicatricial and Infectious Context: A Randomized Clinical Trial","authors":"Maestri Carlos Afonso, Antoniazzi Rodolfo Belz, Maestri Isabela Ceschin, Fernandes Rafaela Ceschin, Fonseca Fernanda Villar","doi":"10.29328/journal.cjog.1001148","DOIUrl":"https://doi.org/10.29328/journal.cjog.1001148","url":null,"abstract":"Introduction: The skills, the techniques utilized in the conization and the hemostasis directly affect the healing process of the cervix tissue. Excessively large excisions and unnecessary use of electrocautery or hemostatic sutures are examples of procedures that may negatively affect the scar cascade and wound healing. Objective: The purpose of this study was to examine the effectiveness of honey-based ferric perchloride paste (HBFPP) in reducing bleeding and infection post-conization procedure. Methods: Prospective randomized clinical trial with a sample of 142 patients randomized in two groups: 78 patients who used the HBFPP (intervention) and 64 patients who did not use the HBFPP (control). Statistical analysis was performed utilizing a significance level of 95%. The Chi-Square test and Fisher’s exact test were applied. Results: Results showed that the mean score of the amount of blood lost was lower in the intervention group compared to the control group. The main complaints reported by the two groups in the postoperative period were discomfort in the genitourinary system, heavy bleeding after surgery, and post-operative infection, but not significantly different among both groups. The control group needed further intervention due to excessive bleeding in comparison with the intervention group. Conclusion: The use of HBFPP reduced the amount of blood lost in the postoperative period of conization surgery.","PeriodicalId":505668,"journal":{"name":"Clinical Journal of Obstetrics and Gynecology","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139284465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0