Epidemiologia & Prevenzione最新文献

{"title":"[Rare Diseases and epidemiology: an overlook at data from the Campania Region Rare Disease Registry (Southern Italy)].","authors":"Annafrancesca Smimmo, Emanuele Monda, Bruno De Rosa, Mario Fordellone, Chiara De Stasio, Anna Fusco, Francesca Marzullo, Martina Caiazza, Marialuisa Mazzella, Salvatore Rega, Sergio Esposito, Ferdinando Russo, Veronica Diana, Concetta Iasevoli, Maria Cristina Boccia, Sabrina Bassolino, Alberto Pagliafora, Giuseppe Fiorentino, Anna Iervolino, Maria Galdo, Ugo Trama, Pietro Buono, Antonio Postiglione, Massimo Di Gennaro, Monica Mazzucato, Paola Facchin, Barbara Morgillo, Maria Giovanna Russo, Paolo Chiodini, Giuseppe Limongelli","doi":"10.19191/EP25.2-3.A776.025","DOIUrl":"https://doi.org/10.19191/EP25.2-3.A776.025","url":null,"abstract":"<p><strong>Objectives: </strong>to provide the epidemiological framework of those affected by rare diseases resident in the Campania Region (Southern Italy), using the data entered in the Campania Region Rare Disease Registry, acquiring information potentially useful for regional planning.</p><p><strong>Design: </strong>observational retrospective cohort study on patients with rare diseases included in the Regione Campania Rare Disease Registry from 01.01.2022 to 31.12.2022.</p><p><strong>Setting and participants: </strong>population included in the Rare Disease Registry and resident in the Campania Region as at 31.12.2022.</p><p><strong>Main outcome measures: </strong>using the data entered in the Regione Campania Rare Disease Registry, the cumulative incidence (I) of patients with rare diseases resident in Campania was calculated, stratified by age group and rare disease group with the respective 95% confidence intervals (IC95%). Standardised cumulative provincial incidences were also calculated. These are reported using a multiplication factor of 100,000.</p><p><strong>Results: </strong>the incidence of patients with rare diseases in the Campania Region is 50.0 (IC95% 49.4-50.6) per 100,000 inhabitants in the year 2022. Furthermore, the rare disease groups with the highest incidence per 100,000 inhabitants are diseases of the central and peripheral nervous system (I: 8.32 per 100,000 inhabitants) and congenital malformations, chromosomopathies and genetic syndromes (I: 8.52 per 100,000 inhabitants). Moreover, the age groups in which the incidence is highest are in the paediatric age group.</p><p><strong>Conclusions: </strong>an epidemiological framework of the Campania Region on rare diseases such as this one for the year 2022 is fundamental for national and regional planning in order to improve the care and quality of life of people affected by rare diseases, who often feel neglected by society. Sharing this type of information also draws attention to the need for faster diagnosis and the specialisation of new centres.</p>","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 2-3","pages":"181-189"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Strengthen and expand vaccination provision in prisons to promote access to preventive tools and health equity].","authors":"Erica De Vita, Maria Paola Tramonti Fantozzi, Davide Petri, Laura Baglietto, Lara Tavoschi","doi":"10.19191/EP25.2-3.050","DOIUrl":"https://doi.org/10.19191/EP25.2-3.050","url":null,"abstract":"","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 2-3","pages":"151-152"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A data-driven approach to optimizing the management of chronic patients within the framework of DM77].","authors":"Maria Teresa Greco, Pietro Magnoni, Walter Bergamaschi, Antonio Giampiero Russo","doi":"10.19191/EP25.2-3.A864.034","DOIUrl":"10.19191/EP25.2-3.A864.034","url":null,"abstract":"<p><strong>Objectives: </strong>to develop tools to identify the most appropriate and/or prioritized sets of patients with stable chronic conditions who are eligible for management by territorial services, to be included in a dedicated care pathway within Community Health Centers (CdC), as outlined in Italian Ministerial Decree 77/2022.</p><p><strong>Design: </strong>retrospective observational study.</p><p><strong>Setting and participants: </strong>subjects residing in the territory of the Health Protection Agency of Milan (ATS Milano) in the year 2023.</p><p><strong>Main outcome measures: </strong>prevalence of hospitalizations, visits to the Emergency Room (ER) and patients receiving polytherapy, defined by specific criteria, to select chronic condition and cohort with potential territorial management. Duration of the disease and visits to the general practitioner (GP) clinic for the chronic population eligible for care in Community Houses provided for by the Italian Ministerial Decree No. 77 (DM77).</p><p><strong>Results: </strong>starting from a population of 3.5 million inhabitants in the ATS Milano, 35% suffer from at least one chronic condition. The most represented pathologies are arterial hypertension (254,232 cases) and hypercholesterolemia (156,314 cases). Applying selection criteria on hospital discharge, access in emergency room, and therapy, 16 chronic pathologies of interest for territorial assistance were identified. The 15% of patients had the disease for less than 1 year while the 36,2% for over 10 years. Over 60,000 patients (10,2%) included in the cohort with potential territorial management did not even make one visit to the GP clinic during 2023.</p><p><strong>Conclusions: </strong>through this model, approximately 600,000 subjects were identified as eligible for territorial care, based on the integration between the GP and the Community House, to be managed preferably within a Territorial Operations Center. This work represents a proposal for the application of a model to the information system available in a structure of the Italian National Health System for the planning of the care of the population affected by chronic diseases, as indicated by the DM77. The possibility of validating and developing similar approaches at a national level could represent a significant step towards better management of chronic conditions.</p>","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 2-3","pages":"168-180"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[One hundred days of the Trump presidency: the risks for science].","authors":"Francesco Barone-Adesi","doi":"10.19191/EP25.2-3.031","DOIUrl":"https://doi.org/10.19191/EP25.2-3.031","url":null,"abstract":"","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 2-3","pages":"116-119"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The effects of the European Pact on Migration and Asylum on the health of migrant populations].","authors":"","doi":"10.19191/EP25.2-3.032","DOIUrl":"https://doi.org/10.19191/EP25.2-3.032","url":null,"abstract":"","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 2-3","pages":"125-128"},"PeriodicalIF":1.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regardless of the true number of deaths, the suffering of Gazans has been immense. And it is not yet over.","authors":"Sandro Colombo","doi":"10.19191/EP25.1.A853.007","DOIUrl":"https://doi.org/10.19191/EP25.1.A853.007","url":null,"abstract":"","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 1","pages":"9-11"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The European Court requires Italy to guarantee independent monitoring procedures].","authors":"Annibale Biggeri","doi":"10.19191/EP25.1.013","DOIUrl":"https://doi.org/10.19191/EP25.1.013","url":null,"abstract":"","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 1","pages":"12-13"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[US leaves WHO: a blow to health multilateralism].","authors":"Roberto Bertollini","doi":"10.19191/EP25.1.008","DOIUrl":"10.19191/EP25.1.008","url":null,"abstract":"","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 1","pages":"14-15"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[\"I don't go out anymore\": an analysis of voluntary social withdrawal among Italian 15-19-year-old students].","authors":"Sonia Cerrai, Silvia Biagioni, Ivan Severi, Leopoldo Grosso, Sabrina Molinaro","doi":"10.19191/EP25.1.A788.011","DOIUrl":"10.19191/EP25.1.A788.011","url":null,"abstract":"<p><strong>Objectives: </strong>to analyse the prevalence and characteristics of the hikikomori phenomenon in Italy within a representative sample of students aged 15 to 19 years, assessing the factors associated with this behaviour to guide preventive interventions.</p><p><strong>Design: </strong>cross-sectional study based on anonymous data collected through the ESPAD®Italia (European School Survey Project on Alcohol and other Drugs) survey using a self-administered questionnaire.</p><p><strong>Setting and participants: </strong>a representative sample of Italian high-school students is selected annually to ensure the comparability of ESPAD®Italia estimates. In this study, the pooled 2021-2023 sample consists of 36,868 students (50.8% male), with an average age of 17.0 years (standard deviation: 1.4).</p><p><strong>Main outcomes measures: </strong>the outcomes analysed are having experienced voluntary social withdrawal for at least six months over a lifetime (Lifetime Hikikomori) and the current behaviour of never leaving the house during the week (Current Withdrawal).</p><p><strong>Results: </strong>in 2023, 2.0% of students reported having voluntarily isolated themselves for at least six months in their lifetime, with a slightly higher prevalence among girls. Current withdrawal involved 11.3% of students, a significant increase compared to the previous two years. In the pooled 2021-2023 sample, the analysis of independent variables showed that the hikikomori phenomenon is associated with the use of psychotropic drugs, cigarette smoking, having been a victim of cyberbullying, feelings of exclusion, dissatisfaction in friendships, risky behaviours related to internet and video game use, and belonging to non-traditional families. The current withdrawal is directly associated with cigarette smoking, lack of enjoyment in social interactions, overweight/obesity, and belonging to non-traditional families.</p><p><strong>Conclusions: </strong>the study provided the first quantitative estimate of voluntary social withdrawal among Italian students aged 15-19 years, confirming that the phenomenon is widespread and concerning, especially among girls. Factors such as the perception of social exclusion, problematic online behaviours and the use of psychotropic drugs are strongly associated with the phenomenon. Future longitudinal research could further explore these relationships and support the development of integrated educational strategies in schools to identify and support at-risk students.</p>","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 1","pages":"35-43"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Risk apportionment to remote and recent asbestos exposures for pleural mesothelioma].","authors":"Alessia Angelini, Paolo Ricci, Dario Mirabelli","doi":"10.19191/EP25.1.A762.002","DOIUrl":"10.19191/EP25.1.A762.002","url":null,"abstract":"<p><strong>Background: </strong>the exposure-response relationship between pleural mesothelioma and asbestos has been traditionally described by models that predicted incidence to increase indefinitely by latency. Studies with long observation showed that the increase flattens out beyond 40 years of latency. It has been, therefore, proposed to introduce an exponential decay function into the models Objectives: to show characteristics and implications as to the relevance of remote and recent exposures, by conducting a simulation exercise based on data available from the literature.</p><p><strong>Methods: </strong>the traditional and decay models that best fit mortality from pleural cancer during the initial 40 years of observation in the Italian pooled cohort of asbestos workers were selected. The mesothelioma incidence predicted by such models as a function of age at first exposure, exposure duration, and age at risk was compared. It was also compared the proportional weight assigned to remote, intermediate, and recent exposure, by dividing the whole exposure period in three parts of equal duration.</p><p><strong>Results: </strong>the decay, but not the traditional, model fits well the trend observed after 40 years. According to the traditional model, remote exposures have maximum and recent exposures minimum weight: for instance, following an exposure starting at age 20 and lasting 18 years, the incidence at age 80 would be attributed to remote exposures by 47% and by 21% to the recent ones. The decay model predicts only minor differences and even of reversed weight: 34% and 31%, respectively, in this case.</p><p><strong>Conclusions: </strong>remote exposures do not necessarily have overwhelming weight in determining pleural mesothelioma risk. The balance between different exposure periods depends on the time-distribution of exposure.</p>","PeriodicalId":50511,"journal":{"name":"Epidemiologia & Prevenzione","volume":"49 1","pages":"54-62"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}