Camilla Cocchi, Maria Beatrice Zazzara, Elena Levati, Riccardo Calvani, Graziano Onder
{"title":"How to promote healthy aging across the life cycle.","authors":"Camilla Cocchi, Maria Beatrice Zazzara, Elena Levati, Riccardo Calvani, Graziano Onder","doi":"10.1016/j.ejim.2025.03.003","DOIUrl":"https://doi.org/10.1016/j.ejim.2025.03.003","url":null,"abstract":"<p><p>The global rise in aging populations is challenging healthcare systems, especially in developed countries. Despite advancements in healthcare and living standards, the extension of lifespan has not been matched by an equivalent improvement in healthspan, leading to a higher prevalence of chronic diseases and disabilities in older adults. This review examines strategies to promote healthy aging throughout the life cycle, emphasizing the importance of a comprehensive strategy that integrates individual, healthcare, and environmental approaches. Individual strategies include lifestyle factors like diet, physical activity, and social connections. Healthcare approaches focus on improving health literacy, vaccinations, and screenings. Environmental approaches aim to mitigate climate change, reduce pollution, and design longevity-ready cities. A comprehensive strategy combining individual approaches, public health measures, innovative policies, and community support is essential for helping populations live longer, healthier, and more independent lives. Looking forward, this will be complemented by personalized approaches, focusing on individual traits and biological backgrounds. The key to this lies in geroscience, which studies the biological and molecular mechanisms of aging and how they contribute to age-related diseases and functional decline, aiming to design targeted interventions to slow aging and improve quality of life. Artificial intelligence will play a key role in analyzing these complex factors and creating innovative solutions. In conclusion, aging is shaped by various factors, requiring more than one solution. A combination of comprehensive and personalized strategies can bridge the gap between public health measures and personalized care, offering the scientific insights needed to slow aging and enhance quality of life.</p>","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefano Fumagalli, Giuseppe Di Pasquale, Giulio Molon, Giancarlo Agnelli, Niccolò Marchionni
{"title":"Apixaban and the improved psychologic profile in frailty and disability. Myth or reality?","authors":"Stefano Fumagalli, Giuseppe Di Pasquale, Giulio Molon, Giancarlo Agnelli, Niccolò Marchionni","doi":"10.1016/j.ejim.2025.03.012","DOIUrl":"https://doi.org/10.1016/j.ejim.2025.03.012","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serum angiopoietin-like protein 4 levels correlate with hypertriglyceridemia and renal function decline in pediatric patients with lupus nephritis.","authors":"Wangqiu Gong, Guanyu Li, Di Lu, Ming Liu, Xia Gao","doi":"10.1016/j.ejim.2025.03.001","DOIUrl":"https://doi.org/10.1016/j.ejim.2025.03.001","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin Liu, Wulamiding Kaisaier, Kai Chen, Beibei Yu, Wengen Zhu
{"title":"Atrial fibrillation ablation versus medical therapy in heart failure with preserved ejection fraction.","authors":"Xin Liu, Wulamiding Kaisaier, Kai Chen, Beibei Yu, Wengen Zhu","doi":"10.1016/j.ejim.2025.03.009","DOIUrl":"https://doi.org/10.1016/j.ejim.2025.03.009","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charles L Bennett, Linda Martin, Gretchen LeFever Watson, Steven T Rosen, David Aboulafia
{"title":"Why did it take forty years to uncover long-term fluoroquinolone associated toxicities?","authors":"Charles L Bennett, Linda Martin, Gretchen LeFever Watson, Steven T Rosen, David Aboulafia","doi":"10.1016/j.ejim.2025.02.027","DOIUrl":"https://doi.org/10.1016/j.ejim.2025.02.027","url":null,"abstract":"","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maximilian Boesch, Florent Baty, Sanjay Kalra, Martin H Brutsche, Frank Rassouli
{"title":"Chronicity of disease mandates quality-of-life prioritization - a role for digital health and patient-reported outcome measures.","authors":"Maximilian Boesch, Florent Baty, Sanjay Kalra, Martin H Brutsche, Frank Rassouli","doi":"10.1016/j.ejim.2025.03.006","DOIUrl":"https://doi.org/10.1016/j.ejim.2025.03.006","url":null,"abstract":"<p><p>NA.</p>","PeriodicalId":50485,"journal":{"name":"European Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":5.9,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}