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Frontiers in Bioscience-Landmark最新文献

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Whole Genome Analysis of Tibetan Kefir-Derived Lactiplantibacillus Plantarum 12-3 Elucidates Its Genomic Architecture, Antimicrobial and Drug Resistance, Potential Probiotic Functionality and Safety 对西藏克菲尔（Kefir）植物乳杆菌 12-3 的全基因组分析阐明了其基因组结构、抗菌性和耐药性、潜在的益生菌功能和安全性
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-11 DOI: 10.31083/j.fbl2904147
Tariq Aziz, M. Naveed, M. A. Shabbir, A. Sarwar, Ayaz Ali Khan, Ammarah Hasnain, Taqweem Ul Haq, Zhennai Yang, A. Zinedine, João Miguel Rocha, M. Alharbi
{"title":"Whole Genome Analysis of Tibetan Kefir-Derived Lactiplantibacillus Plantarum 12-3 Elucidates Its Genomic Architecture, Antimicrobial and Drug Resistance, Potential Probiotic Functionality and Safety","authors":"Tariq Aziz, M. Naveed, M. A. Shabbir, A. Sarwar, Ayaz Ali Khan, Ammarah Hasnain, Taqweem Ul Haq, Zhennai Yang, A. Zinedine, João Miguel Rocha, M. Alharbi","doi":"10.31083/j.fbl2904147","DOIUrl":"https://doi.org/10.31083/j.fbl2904147","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"19 10","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140714646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Profiles, Distribution, and Functions of Gamma Delta T Cells in Ocular Surface Homeostasis and Diseases 眼表稳态和疾病中γ-ΔT 细胞的特征、分布和功能
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-11 DOI: 10.31083/j.fbl2904146
Zhengze Sun, Haolan Ji, Yifan Zhou, H. Duan, B. Ma, H. Qi
{"title":"Profiles, Distribution, and Functions of Gamma Delta T Cells in Ocular Surface Homeostasis and Diseases","authors":"Zhengze Sun, Haolan Ji, Yifan Zhou, H. Duan, B. Ma, H. Qi","doi":"10.31083/j.fbl2904146","DOIUrl":"https://doi.org/10.31083/j.fbl2904146","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"35 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Cell Specific Effect of MBOAT7 MAFLD-risk Variant on Immune Cells MBOAT7 MAFLD 风险变体对免疫细胞的细胞特异性影响
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-11 DOI: 10.31083/j.fbl2904148
Ziyang Pan, Jawaher Alharthi, A. Bayoumi, Jacob George, M. Eslam
{"title":"A Cell Specific Effect of MBOAT7 MAFLD-risk Variant on Immune Cells","authors":"Ziyang Pan, Jawaher Alharthi, A. Bayoumi, Jacob George, M. Eslam","doi":"10.31083/j.fbl2904148","DOIUrl":"https://doi.org/10.31083/j.fbl2904148","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"5 3","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140715476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UBA2 as a Prognostic Biomarker and Potential Therapeutic Target in Glioma 作为胶质瘤预后生物标志物和潜在治疗靶点的 UBA2
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-09 DOI: 10.31083/j.fbl2904144
Yuhong Ou, Hongtao Luo, Qiuning Zhang, Tianqi Du, Ruifeng Liu, Dandan Wang, Junru Chen, Meng Dong, Yuhang Wang, Zhen Yang, Xiaohu Wang
{"title":"UBA2 as a Prognostic Biomarker and Potential Therapeutic Target in Glioma","authors":"Yuhong Ou, Hongtao Luo, Qiuning Zhang, Tianqi Du, Ruifeng Liu, Dandan Wang, Junru Chen, Meng Dong, Yuhang Wang, Zhen Yang, Xiaohu Wang","doi":"10.31083/j.fbl2904144","DOIUrl":"https://doi.org/10.31083/j.fbl2904144","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"67 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140723683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progenitor Cell Function and Cardiovascular Remodelling Induced by SGLT2 Inhibitors SGLT2 抑制剂诱导的祖细胞功能和心血管重塑
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-09 DOI: 10.31083/j.fbl2904145
Theodora M Stougiannou, Konstantinos C. Christodoulou, T. Koufakis, F. Mitropoulos, Dimitrios Mikroulis, Cyril David Mazer, Dimos Karangelis
{"title":"Progenitor Cell Function and Cardiovascular Remodelling Induced by SGLT2 Inhibitors","authors":"Theodora M Stougiannou, Konstantinos C. Christodoulou, T. Koufakis, F. Mitropoulos, Dimitrios Mikroulis, Cyril David Mazer, Dimos Karangelis","doi":"10.31083/j.fbl2904145","DOIUrl":"https://doi.org/10.31083/j.fbl2904145","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"22 10","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140722007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Metabolism of Coenzyme A and Its Derivatives Plays a Crucial Role in Diseases 辅酶 A 及其衍生物的代谢在疾病中发挥着至关重要的作用
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-09 DOI: 10.31083/j.fbl2904143
Jumin Xie, Xingyuan Chen, Mei Zheng, Jingzhe Zhu, Hui Mao
{"title":"The Metabolism of Coenzyme A and Its Derivatives Plays a Crucial Role in Diseases","authors":"Jumin Xie, Xingyuan Chen, Mei Zheng, Jingzhe Zhu, Hui Mao","doi":"10.31083/j.fbl2904143","DOIUrl":"https://doi.org/10.31083/j.fbl2904143","url":null,"abstract":"Coenzyme A (CoA) functions as a crucial carrier of acyl groups within cells, playing a fundamental role in regulating acyl transfer reactions and participating in cellular metabolic processes. As the principal substrate and cofactor engaged in diverse metabolic reactions, CoA and its derivatives exert central influence over various physiological processes, primarily modulating lipid and ketone metabolism, as well as protein modification. This paper presents a comprehensive review of the molecular mechanisms by which CoA influences the onset and progression of cancer, cardiovascular disease (CVD), neurodegenerative disorders, and other illnesses. The main focal points include the following. (1) In cancer, enzymes such as acetyl-CoA synthetase 2, ATP citrate lyase, and acetyl-CoA carboxylase regulate lipid synthesis and energy metabolism by modulating acetyl-CoA levels. (2) In CVD, the effects of enzymes such as stearoyl-CoA desaturase-1, 3-hydroxy-3-methylglutaryl-CoA (HMGC) synthase 2, and HMGC reductase on the formation and advancement of these diseases are elucidated by their regulation of CoA metabolism across multiple organs. (3) In neurodegenerative disorders, the significance of CoA in maintaining cholesterol homeostasis in the brain and its implications on the development of such disorders are thoroughly discussed. The metabolic processes involving CoA and its derivatives span all physiological aspects within cells, playing a critical role in the onset and progression of various diseases. Elucidating the role of CoA in these conditions yields important insights that can serve as valuable references and guidance for disease diagnosis, treatment, and drug development.","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"120 11","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140724697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress of Pericytes in Pulmonary Fibrosis 肺纤维化中的周细胞研究进展
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-08 DOI: 10.31083/j.fbl2904141
Xiaobo He, Yuanhang Fan, Yihuan Lai, Ying Yang, Xiao Xiao Tang, Yichun Wang
{"title":"Research Progress of Pericytes in Pulmonary Fibrosis","authors":"Xiaobo He, Yuanhang Fan, Yihuan Lai, Ying Yang, Xiao Xiao Tang, Yichun Wang","doi":"10.31083/j.fbl2904141","DOIUrl":"https://doi.org/10.31083/j.fbl2904141","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"38 10","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140728312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deciphering the Enigma of Neuron-Glial Interactions in Neurological Disorders 破解神经系统疾病中神经元与神经胶质细胞相互作用之谜
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-08 DOI: 10.31083/j.fbl2904142
S. R. Ahmad, Md. Zeyaullah, Abdullah M. AlShahrani, Adam Dawria, Haroon Ali, Ali Mohieldin, Abdelrhman AG Altijani, Ufaq Razi, Munzila Mehdi, Sabika Akram, Ejaz Rizvi Hussain
{"title":"Deciphering the Enigma of Neuron-Glial Interactions in Neurological Disorders","authors":"S. R. Ahmad, Md. Zeyaullah, Abdullah M. AlShahrani, Adam Dawria, Haroon Ali, Ali Mohieldin, Abdelrhman AG Altijani, Ufaq Razi, Munzila Mehdi, Sabika Akram, Ejaz Rizvi Hussain","doi":"10.31083/j.fbl2904142","DOIUrl":"https://doi.org/10.31083/j.fbl2904142","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"39 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140729922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CD146 Promotes EMT-Mediated Migration and Invasion of NSCLC via PI3K/Akt Signaling Pathway CD146 通过 PI3K/Akt 信号通路促进 EMT 介导的 NSCLC 迁移和侵袭
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-08 DOI: 10.31083/j.fbl2904140
Nan Wei, Xuan Wu, Yi Yu, Huanhuan Zhou, Kai Cui, Xingru Zhao, Xiaoju Zhang
{"title":"CD146 Promotes EMT-Mediated Migration and Invasion of NSCLC via PI3K/Akt Signaling Pathway","authors":"Nan Wei, Xuan Wu, Yi Yu, Huanhuan Zhou, Kai Cui, Xingru Zhao, Xiaoju Zhang","doi":"10.31083/j.fbl2904140","DOIUrl":"https://doi.org/10.31083/j.fbl2904140","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"87 5‐6","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140731772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human Placenta-Derived Mesenchymal Stem Cells Improve Neurological Function in Rats with Intrauterine Hypoxic-Ischaemic Encephalopathy by Reducing Apoptosis and Inflammatory Reactions 人胎盘间充质干细胞通过减少细胞凋亡和炎症反应改善宫内缺氧缺血性脑病大鼠的神经功能
IF 3.1 4区 生物学
Frontiers in Bioscience-Landmark Pub Date : 2024-04-03 DOI: 10.31083/j.fbl2904139
Yi-Qi Zhao, Yun-Yi Xu, Yan-Mei Zheng, Fei Han, Ying Zhang, Ruo-Lang Pan, Jia-Rong Chen, Yu-Mei Hao, Li-Wei Yang
{"title":"Human Placenta-Derived Mesenchymal Stem Cells Improve Neurological Function in Rats with Intrauterine Hypoxic-Ischaemic Encephalopathy by Reducing Apoptosis and Inflammatory Reactions","authors":"Yi-Qi Zhao, Yun-Yi Xu, Yan-Mei Zheng, Fei Han, Ying Zhang, Ruo-Lang Pan, Jia-Rong Chen, Yu-Mei Hao, Li-Wei Yang","doi":"10.31083/j.fbl2904139","DOIUrl":"https://doi.org/10.31083/j.fbl2904139","url":null,"abstract":"","PeriodicalId":50430,"journal":{"name":"Frontiers in Bioscience-Landmark","volume":"522 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140749432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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