CHEMISTRY PROGRESS最新文献

{"title":"Pembuatan Sabun Mandi Transparan VCO dengan Penambahan Ekstrak Biji Alpukat Sebagai Antioksidan dan Antibakteri Alami","authors":"Timothy Turangan, D. G. Katja, H. Aritonang","doi":"10.35799/cp.16.2.2023.49423","DOIUrl":"https://doi.org/10.35799/cp.16.2.2023.49423","url":null,"abstract":"Telah dilakukan penelitian tentang pembuatan sabun mandi transparan berbahan dasar Virgin Coconut Oil dengan penambahan ekstrak biji alpukat sebagai bahan aktif dalam sabun. Mutu sabun yang dihasilkan dianalisis berdasarkan SNI 3532:2021 tentang Sabun Mandi Padat. Aktivitas antioksidan ditentukan menggunakan metode penangkapan radikal bebas DPPH dan aktivitas antibakteri diuji dengan metode difusi cakram kertas (Kirby-Bauer). Sabun yang dibuat dengan penambahan ekstrak biji alpukat tidak memenuhi SNI untuk parameter total lemak dan kadar klorida. Sabun tanpa penambahan ekstrak biji alpukat tidak memenuhi kriteria SNI untuk parameter total lemak, kadar klorida dan lemak tak tersabunkan. Sabun dengan penambahan ekstrak biji alpukat memiliki aktivitas penangkal radikal bebas dengan nilai IC50 sebesar 17,17 μg/mL yang tergolong sangat kuat. Aktivitas antibakteri dari sabun dengan penambahan ekstrak biji alpukat memberikan hasil zona hambat yang tergolong sedang terhadap bakteri Staphylococcus aureus dan bakteri Pseudomonas aeruginosa. A research was conducted on the manufacture of transparent bath soap made from Virgin Coconut Oil with the addition of avocado seed extract as an active ingredient. The quality of the soap produced was analyzed based on SNI 3532:2021 concerning Solid Bath Soap. Antioxidant activity was examined using the DPPH free radical scavenging method and the antibacterial activity was tested using the paper disc diffusion method (Kirby-Bauer). Soap made with the addition of avocado seed extract did not meet the conditions required by SNI for total fat and chloride content. Soap without the addition of avocado seed extract did not qualify by SNI for the parameters of total fat, chloride content, and unsaponifiable fat. Soap with the addition of avocado seed extract has very strong free radical scavenging activity with an IC50 value of 17,17 μg/mL. The soap with the addition of avocado seed extract showed antibacterial activity resulted in a moderate inhibition zone against Staphylococcus aureus and Pseudomonas aeruginosa.","PeriodicalId":504121,"journal":{"name":"CHEMISTRY PROGRESS","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139232340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolasi Nanoselulosa Pelepah Aren ( Arenga pinnata Merr.) untuk Menurunkan Kandungan Sianida dalam Limbah Tambang Emas Rakyat Sulawesi Utara","authors":"Ervi Tandi Sangbara, Hotma Pretty Lestari Tampubolon, Fitriani Mandalurang, Marchelino Christofel Muaja, Regina Pairunan, A. Wuntu","doi":"10.35799/cp.16.2.2023.52459","DOIUrl":"https://doi.org/10.35799/cp.16.2.2023.52459","url":null,"abstract":"North Sulawesi is one of the areas that conducts small-scale gold mining. In recent years, small-scale gold mining has used the cyanidation method in gold processing, which can cause tailings containing cyanide and heavy metals. Cyanide is a toxic compound. Therefore, cyanide in wastewater should not exceed a concentration of 0.5 ppm in accordance with wastewater quality standards. The presence of cyanide in wastewater can be minimised by adsorbing. Biodsorbents that are widely used are adsorbents containing natural polymers, one of which is cellulose. One of the biomass that contains cellulose is palm fronds, which is 66.5%. Cellulose can be isolated into nanocellulose and utilised effectively to remove contaminants in waste. The purpose of this study was to isolate cellulose and nanocellulose from palm fronds (Arenga pinnata Merr.) and determine the ability of palm frond nanocellulose to reduce cyanide content in North Sulawesi gold mining waste.  The nanocellulose produced was characterised by FTIR, SEM-EDS, XRD and PSA. From the analysis results, cellulose was 47.04% and nanocellulose was 41.26%. The maximum cyanide adsorbing capacity occurred at a mass of 2 g nanocellulose with a contact time of 120 minutes and pH 13, which was 52.45%.","PeriodicalId":504121,"journal":{"name":"CHEMISTRY PROGRESS","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139235301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formulasi Pasta Gigi Herbal Ekstrak Etanol Kulit Buah Lemon Suanggi (Citrus limon (L.) Burm. f.) Sebagai Agen Antibakteri Streptococcus mutans","authors":"Beatrice Kezya Simaremare, Paulina V. Y. Yamlean, J. P. Siampa","doi":"10.35799/cp.16.2.2023.48447","DOIUrl":"https://doi.org/10.35799/cp.16.2.2023.48447","url":null,"abstract":"Lemon Suanggi (Citrus limon (L.) Burm. f.) banyak dibudidayakan di Kawasan Asia selatan berpotensi sebagai agen antibakteri. Lapisan bagian dalam kulit buah lemon suanggi terdiri atas glikosida, kumarin, dan flavonoid yang dapat berperan sebagai antibakteri, anti mikroba dan antioksidan alami. Penelitian ini bertujuan untuk mengetahui kandungan fitokimia dari ekstrak kulit buah lemon suanggi, aktivitas antibakteri dari ekstrak kulit buah lemon suanggi terhadap Streptococcus mutans, untuk memformulasikan ekstrak kulit buah lemon suanggi ke dalam bentuk sediaan pasta gigi, mengevaluasi stabilitas sediaan selama 14 hari dan menguji efektivitas antibakteri sediaan pasta gigi ekstrak kulit buah lemon suanggi. Untuk mengetahui kandungan fitokimia ekstrak dilakukan dengan skrining fitokimia terhadap ekstrak dan didapat positif memiliki kandugan senyawa metabolit sekunder antara lain Alkaloid, Flavonoid, Tanin, Steroid, dan Saponin. Pengujian antibakteri dilakukan dengan metode difusi cakram terhadap ekstrak kulit buah lemon suanggi dengan konsentrasi 2, 4, dan 6% menggunakan pelarut DMSO dan diukur diameter zona bening yang terbentuk. Hasil rata-rata diameter zona bening yang terbentuk masing – masing adalah 12,8mm, 13,5mm, dan 14,5mm. Hasil dari uji antibakteri sediaan pasta gigi herbal F1 (2%)= 12,5mm, F2(4%)= 14mm, dan F3(6%)= 15,6mm. Formulasi pasta gigi herbal dilakukan dengan tiga formula yang berbeda konsentrasi zat aktifnya. Uji evaluasi yang digunakan adalah uji pH, uji daya sebar, dan uji tinggi busa yang menunjukkan hasil yang sesuai dengan syarat sediaan pasta gigi. Lemon Suanggi (Citrus limon (L.) Burm. f.) is widely cultivated in the South Asian region as a potential antibacterial agent. The inner layer of suanggi lemon peel consists of glycosides, coumarins, and flavonoids which can act as natural antibacterial, anti-microbial and antioxidant. This study was aimed to determine the phytochemical content of suanggi lemon peel extract and the antibacterial activity of suanggi lemon peel extract against Streptococcus mutans, to formulate suanggi lemon peel extract into toothpaste dosage form, and to evaluate the stability of the preparation for 14 days and the antibacterial effectiveness of suanggi lemon peel extract toothpaste. To determine the phytochemical content of the extract, phytochemical screening was carried out on the extract and it was found positive for secondary metabolite compounds, including alkaloids, flavonoids, tannins, steroids, and saponins. Antibacterial testing was carried out using the disc diffusion method on suanggi lemon peel extract with a concentration of 2, 4, and 6% using DMSO solvent and the diameter of the clear zone formed was measured. The average diameters of the clear zone formed were 12.8mm, 13.5mm and 14.5mm, respectively. The results of the antibacterial test for herbal toothpaste preparations F1 (2%)= 12.5mm, F2(4%)= 14mm, and F3(6%)= 15.6mm. Formulation of herbal toothpaste was carried out using three","PeriodicalId":504121,"journal":{"name":"CHEMISTRY PROGRESS","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139235846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profil Kromatogram dari Variasi Konsentrasi Pelarut Etanol Ekstrak Daun Leilem Serta Penentuan Nilai SPF","authors":"E. Suoth, K. L. Mansauda, D. Mpila, Suryana Sumantri","doi":"10.35799/cp.16.2.2023.51733","DOIUrl":"https://doi.org/10.35799/cp.16.2.2023.51733","url":null,"abstract":"This research aims to look at the chromatogram profile of leilem leaf extract with 50% ethanol, 70% ethanol and 95% ethanol as solvents. Extraction was carried out by maceration and then the secondary metabolite profile was viewed using the thin layer chromatography method. The eluent used was a mixture of n-hexane and ethyl acetate solvents with several comparisons, then the extract was tested for antioxidant activity and the SPF value was determined. The research continued with making a gel preparation with the active ingredient leilem leaf extract as well as testing the antioxidant and SPF values of the gel preparation. The results obtained from the chromatogram profile of the 70% and 95% ethanol extracts contained many spots that appeared after being observed under 366 nm UV light, whereas the 50% ethanol extract showed separation spots only under UV 254 light at a solvent ratio of n-hexane: ethyl acetate 10: 1. The antioxidant results using the DPPH method showed the percent inhibition value of 70% ethanol extract, namely 57.6, while the 50% ethanol extract gel preparation showed the highest percent inhibition, namely 68.9. The SPF value of the extract increases after being formulated in a gel preparation.","PeriodicalId":504121,"journal":{"name":"CHEMISTRY PROGRESS","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139236016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fotodegradasi Zat Warna Methylene Blue Menggunakan Komposit Kitosan/Ag","authors":"Gillby Laseduw, H. Aritonang, V. Kamu","doi":"10.35799/cp.16.2.2023.48415","DOIUrl":"https://doi.org/10.35799/cp.16.2.2023.48415","url":null,"abstract":"Telah disintesis kitosan yang terdoping dengan nanopartikel Ag dalam suatu komposit kitosan/Ag menggunakan metode kopresipitasi dimana kitosan berperan sebagai penstabil dan glutaraldehida sebagai agen pengikat silang. Sifat struktural, elemental, dan morfologi telah dianalisis menggunakan FTIR, SEM-EDX, dan XRD untuk mengetahui apakah komposit kitosan/Ag telah terbentuk dengan hasil yang didapatkan bahwa komposit kitosan/Ag telah terbentuk dengan ukuran kristalit sebesar 2,06 nm. Aktivitas fotokatalitik dari komposit kitosan/Ag telah dilakukan dengan iradiasi zat warna methylene blue menggunakan lampu UV. Berdasarkan hasil yang diperoleh, komposit kitosan/Ag memiliki kemampuan fotokatalis yang bagus dalam mendegradasi zat warna methylene blue dengan waktu kontak optimum pada waktu 90 menit. Chitosan doped with Ag nanoparticles in a chitosan/Ag composite was synthesized using the coprecipitation method where chitosan acts as a stabilizer and glutaraldehyde as a crosslinking agent. Structural, elemental, and morphological properties were analyzed using FTIR, SEM-EDX, and XRD to observe the formation of the chitosan/Ag composite. It was shown that the chitosan/Ag composite was formed with a crystallite size of 2.06 nm. The photocatalytic activity of the chitosan/Ag composite was examined by irradiating methylene blue under UV lamp. Based on the results obtained, the chitosan/Ag composite had good photocatalytic ability to degrade methylene blue dye with an optimum contact time of 90 minutes.","PeriodicalId":504121,"journal":{"name":"CHEMISTRY PROGRESS","volume":"176 12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139236054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}