Dermato最新文献 - Book学术

Assessment of Micellar Water pH and Product Claims 微晶水 pH 值和产品声明评估

Dermato Pub Date : 2024-07-11 DOI: 10.3390/dermato4030009

Dēna Skadiņa, Ināra Nokalna, Alise Balcere

{"title":"Assessment of Micellar Water pH and Product Claims","authors":"Dēna Skadiņa, Ināra Nokalna, Alise Balcere","doi":"10.3390/dermato4030009","DOIUrl":"https://doi.org/10.3390/dermato4030009","url":null,"abstract":"Micellar waters are widely used skincare cleansing products. It is commonly considered that micellar waters do not need to be rinsed off. Products left on the skin can affect its pH, which typically ranges from 4.1 to 5.8. and plays a vital role in maintaining the integrity of the skin barrier. Our objective was to evaluate the pH of micellar waters and investigate product claims, and differences according to target skin type. The pH of 30 samples of different micellar waters was tested. The products were categorized into groups based on target skin type. Statistical analysis was performed on both quantitative and qualitative data. In addition to descriptive statistics, the Shapiro–Wilk test, Fischer’s Exact test, and the Kruskal–Wallis test were used considering the minimal significance level of 95%. The pH of the tested micellar waters ranged from 4.25 to 7.87. Most samples, 21 (70%), claimed to have a no-rinse formula. Most products, 18 (60%), also reported some type of testing having been performed. There were no statistically significant differences in pH between target skin types but products “for all skin types” were the most likely to lack rinsing instructions. In conclusion, most micellar water samples had skin-friendly pH levels and providers should carefully consider product characteristics for patients with skin conditions.","PeriodicalId":504042,"journal":{"name":"Dermato","volume":"92 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141657855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare Presentation, Critical Diagnosis: Primary Actinomycosis of the Foot 罕见表现，关键诊断：足部原发性放线菌病

Dermato Pub Date : 2024-07-04 DOI: 10.3390/dermato4030008

Alexandra Maria Dorobanțu, M. Lupu, L. Popa, Raluca Tătar, C. Giurcaneanu, Irina Tudose, O. Orzan

{"title":"Rare Presentation, Critical Diagnosis: Primary Actinomycosis of the Foot","authors":"Alexandra Maria Dorobanțu, M. Lupu, L. Popa, Raluca Tătar, C. Giurcaneanu, Irina Tudose, O. Orzan","doi":"10.3390/dermato4030008","DOIUrl":"https://doi.org/10.3390/dermato4030008","url":null,"abstract":"Actinomycosis, an uncommon granulomatous infection caused by the Actinomyces species, rarely targets as primary involvement the limb and is often linked to traumatic incidents. In this report, we present the case of a 44-year-old female who developed multiple small nodules on her left foot over approximately 12 months. Some nodules exhibited firmness and a violet hue, while others discharged a yellowish fluid. The patient had no significant comorbidities. Despite thorough blood paraclinical assessments, including complete blood count, serological HIV testing, and QuantiFERON-TB Gold testing, no abnormalities were detected. Bacteriological examinations and cultures of the discharge yielded negative results. Dermatoscopic examination revealed ovoid yellowish structures, with confocal microscopy highlighting granulomas. A subsequent skin biopsy confirmed characteristic changes indicative of actinomycosis. Although systemic antibiotic therapy with penicillin derivatives was initially considered, the patient’s documented allergic history to this medication class, verified through allergological testing, prompted the initiation of doxycycline treatment. Notably, significant improvement was observed at the 3-month follow-up. This case underscores the importance of reporting rare instances of actinomycosis due to its diagnostic complexity and management challenges.","PeriodicalId":504042,"journal":{"name":"Dermato","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141677807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Transition from Pemphigus Foliaceus to Pemphigus Vegetans—An Intriguing Phenomenon within the Spectrum of Autoimmune Blistering Diseases: A Case Report 从叶状天疱疮到植物性天疱疮的转变--自身免疫性水疱病谱中的一个有趣现象：病例报告

Dermato Pub Date : 2024-06-14 DOI: 10.3390/dermato4020007

O. Orzan, L. Popa, Iulia Badiu, Ana Ion, C. Giurcaneanu, Beatrice Bălăceanu-Gurău, Irina Tudose

引用次数: 0

Prevention of Occupational Skin Cancer Caused by Solar Ultraviolet Radiation Exposure: Recent Achievements and Perspectives 预防暴露于太阳紫外线辐射导致的职业性皮肤癌：最新成果与展望

Dermato Pub Date : 2024-06-06 DOI: 10.3390/dermato4020006

C. Symanzik, S. M. John

{"title":"Prevention of Occupational Skin Cancer Caused by Solar Ultraviolet Radiation Exposure: Recent Achievements and Perspectives","authors":"C. Symanzik, S. M. John","doi":"10.3390/dermato4020006","DOIUrl":"https://doi.org/10.3390/dermato4020006","url":null,"abstract":"In fair-skinned populations worldwide, skin cancer is a serious public health threat. A significant percentage of all reported occupational diseases fall back on skin cancer. Over the past few decades, there has been a rise in the frequency of skin cancer diagnoses among outdoor workers. The main cause of non-melanoma skin cancer is solar ultraviolet radiation (UVR), which is also the most common occupational carcinogenic exposure in terms of the number of exposed workers (i.e., outdoor workers). Sun protection—and concomitantly the prevention of occupational skin cancer—is a component of workplace safety. The risks of solar UVR exposure at work are often disregarded in practice, despite the recent recognition of the need for measures to support outdoor workers’ sun protection behavior. It is anticipated that occupational dermatology will become increasingly focused on sun safety in the coming decades. To handle current hurdles in a sustainable manner, the full range of preventive measures should be utilized. Existing strategies for the prevention of occupational skin cancer might be evolved and enriched by new (educational) concepts, methods, and/or technologies. In this, not only components of general prevention and individual prevention but also setting-based prevention and behavior-based prevention might be freshly thought through.","PeriodicalId":504042,"journal":{"name":"Dermato","volume":"23 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141379088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Presentation of Acrodermatitis Chronica Atrophicans Resulting in Delay of Diagnosis and Inappropriate Treatment in Three Cases 三例慢性萎缩性皮炎表现不寻常，导致诊断延误和治疗不当

Dermato Pub Date : 2024-05-02 DOI: 10.3390/dermato4020005

T. Gambichler, Rim Jridi, Heinz-Wolfram Bernd, Andrea von Stemm, S. Boms

引用次数: 0

Eosinophil-Count-Derived Inflammatory Markers and Psoriasis Severity: Exploring the Link 嗜酸性粒细胞计数衍生的炎症标记物与牛皮癣严重程度：探索联系

Dermato Pub Date : 2024-04-15 DOI: 10.3390/dermato4020004

Oana Mirela Tiucă, S. H. Morariu, Claudia Raluca Mariean, Robert Aurelian Tiucă, A. Nicolescu, O. Cotoi

{"title":"Eosinophil-Count-Derived Inflammatory Markers and Psoriasis Severity: Exploring the Link","authors":"Oana Mirela Tiucă, S. H. Morariu, Claudia Raluca Mariean, Robert Aurelian Tiucă, A. Nicolescu, O. Cotoi","doi":"10.3390/dermato4020004","DOIUrl":"https://doi.org/10.3390/dermato4020004","url":null,"abstract":"Psoriasis is an immune-mediated disease, with various triggering factors, genetic predisposition, and an altered immune response concurring in the development of this disease. The eosinophil is a cell with an important role in various kinds of inflammatory processes. Scarce data are available regarding the role of the eosinophil in psoriasis. This study aims to address the overall relationship between eosinophil-count-derived inflammatory markers and psoriasis severity. There were 366 patients fulfilling the inclusion criteria included in this retrospective study and they were divided based on the body surface area (BSA) scale in mild and moderate-to-severe psoriasis. White blood cell (WBC), neutrophil, lymphocyte, monocyte, and eosinophil count, along with eosinophil-to-monocyte ratio (EMR) and eosinophil-to-neutrophil ratio (ENR) differed significantly between the two study groups. Eosinophil count, EMR, and ENR negatively correlated with disease severity. ENR is the most reliable eosinophil-count-derived marker in assessing psoriasis severity with an AUC of 0.627 and a cut-off value of 0.03. Eosinophil-count-derived inflammatory markers’ usefulness in appreciating disease severity was assessed for the first time in the literature in this study and proved to be reliable for the eosinophil count, EMR, and ENR.","PeriodicalId":504042,"journal":{"name":"Dermato","volume":"5 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140702854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Updated Scope of Dermato Dermato 的最新范围

Dermato Pub Date : 2024-03-26 DOI: 10.3390/dermato4020003

T. Gambichler, Chalid Assaf

引用次数: 0

Considering Phytosphingosine-Based Ceramide Formulations for Atopic Skin Care 考虑将基于植物鞘氨醇的神经酰胺配方用于特应性皮肤护理

Dermato Pub Date : 2024-03-13 DOI: 10.3390/dermato4010002

Dalibor Mijaljica, Joshua P. Townley, Angelina Hondros, Caroline Hewson, Ian P Harrison, Fabrizo Spada

{"title":"Considering Phytosphingosine-Based Ceramide Formulations for Atopic Skin Care","authors":"Dalibor Mijaljica, Joshua P. Townley, Angelina Hondros, Caroline Hewson, Ian P Harrison, Fabrizo Spada","doi":"10.3390/dermato4010002","DOIUrl":"https://doi.org/10.3390/dermato4010002","url":null,"abstract":"This review provides an overview of the structural and functional features of key phytosphingosine-based ceramides (CERs), notably CER[EOP], CER[NP], and CER[AP], and their role in atopic skin health. Herein, we discuss how these indispensable stratum corneum (SC) lipids maintain skin barrier homeostasis and contribute to the skin’s barrier function in terms of its cohesiveness and resilience. We also consider the usefulness of CER[EOP], CER[NP], and CER[AP] in preserving skin hydration and protecting and/or repairing dry, itchy, or sensitive skin. Next, we explore how and to what extent an imbalance or inadequate amounts of CER[EOP], CER[NP], and CER[AP] contribute to the hallmark characteristics of atopic skin diseases like eczema. Furthermore, we discuss the importance of complementary SC resident lipids such as cholesterol (CHOL) and free fatty acids (FFAs), which are crucial for optimal CER function. Studies have shown that delivering topical CERs in balanced and optimal combination with CHOL and FFAs—while supporting and boosting the endogenous biosynthesis of CERs using ingredients such as niacinamide and lactic acid—helps relieve symptoms of atopic diseases to provide some measure of relief. Finally, we look at some emerging ingredients that can complement the science of CERs in healthy and diseased skin.","PeriodicalId":504042,"journal":{"name":"Dermato","volume":"619 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140246611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Juvenile-Onset Non-Poikilodermatous CD8+CD56+ Mycosis Fungoides 青少年发病型非鳞屑性 CD8+CD56+ 真菌病

Dermato Pub Date : 2024-01-08 DOI: 10.3390/dermato4010001

T. Gambichler, Andrea Thiele, Hartmut Merz, L. Susok, S. Boms

{"title":"Juvenile-Onset Non-Poikilodermatous CD8+CD56+ Mycosis Fungoides","authors":"T. Gambichler, Andrea Thiele, Hartmut Merz, L. Susok, S. Boms","doi":"10.3390/dermato4010001","DOIUrl":"https://doi.org/10.3390/dermato4010001","url":null,"abstract":"The most frequent primary cutaneous lymphomas observed in childhood and adolescence are mycosis fungoides (MF) and CD30-positive lymphoproliferative diseases. We report a 22-year-old female who presented with a 6-year history of multiple well-demarcated large roundish-oval scaly and reddish-brownish patches and plaques on the trunk and extremities. Histopathology revealed the focal parakeratosis and prominent epidermotropism of atypical lymphocytes, which were positive for CD8, CD56, and TIA-1 and showed a loss of CD7 and CD5 expression. T-cell receptor (TCR) gene rearrangement analysis (multiplex-PCR, BIOMED-2) of the lesional skin demonstrated the rearrangement of the gamma chain (tube A: 162 nt). Based on clinicopathological findings and a complete work-up, she was diagnosed with juvenile non-poikilodermatous C8+/CD56+ MF in stage IA. Resolution of the skin lesions was achieved by 16-week narrowband UVB phototherapy and clobetasol propionate 0.05% ointment. Juvenile-onset non-poikilodermatous CD8+CD56+ MF represents a very rare MF subtype and is associated with an indolent course. In order to avoid too aggressive diagnostics and treatments, clinicians should be aware of this rare and indolent MF variant in childhood and adolescence.","PeriodicalId":504042,"journal":{"name":"Dermato","volume":"18 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139445368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adenosquamous Carcinoma of the Skin: A Case Report 皮肤腺鳞癌：病例报告

Dermato Pub Date : 2023-12-13 DOI: 10.3390/dermato3040020

Rim Jridi, Franziska Hartmann, S. Boms, Andrea Tannapfel, Thilo Gambichler

引用次数: 0