Medical & Clinical Research最新文献_第3页

Adaptive Phenotypes: Their Material Bases, Criteria and Proofs: A Review 适应性表型：其物质基础、标准和证明：综述

Medical & Clinical Research Pub Date : 2023-11-15 DOI: 10.33140/mcr.08.11.06

引用次数: 0

COVID-19 Vaccination Effectively Reduces Pneumonia Severity as Assessed by Routine Chest Computed Tomography 接种 COVID-19 疫苗可有效降低常规胸部计算机断层扫描评估的肺炎严重程度

Medical & Clinical Research Pub Date : 2023-11-15 DOI: 10.33140/mcr.08.11.07

{"title":"COVID-19 Vaccination Effectively Reduces Pneumonia Severity as Assessed by Routine Chest Computed Tomography","authors":"","doi":"10.33140/mcr.08.11.07","DOIUrl":"https://doi.org/10.33140/mcr.08.11.07","url":null,"abstract":"Background: In China, the COVID-19 outbreak infected more than 80% of the population. Few trials have been conducted to assess the effectiveness of the China-manufactured vaccine against COVID-19. Purpose: The purpose of this study was to evaluate the severity of pneumonia in individuals with COVID-19 who were fully vaccinated, partially vaccinated, and unvaccinated, using routine chest computed tomography. Materials and Methods: We analyzed data from patients (aged >18 years) who were hospitalized due to COVID-19 pneumonia between December 2022 and January 2023. Patients who underwent routine chest CT scans were divided into three groups based on their vaccination status. The lobar involvement grading system (0-25) was used to assess the extent of lung injury. The primary outcome was either survival or death. The Pearson chi-square test, Fisher's exact test, and one-way ANOVA were used to compare clinical and imaging features. The receiver operating characteristic (ROC) curve analysis was used to calculate the area under the curve (AUC), sensitivity, and specificity of the CT severity score (CT-SS) in relation to the outcome. Results: Of the 94 patients with COVID-19 pneumonia, 39 patients (41%) were fully vaccinated, 14 (15%) were partially vaccinated, and 41 (44%) were unvaccinated. Among patients with COVID-19 pneumonia, the mean CT severity scores (CT-SS) were 5.9 ± 4.0, 6.5 ± 4.9, and 8.9 ± 4.5 for fully vaccinated individuals, partially vaccinated individuals, and unvaccinated individuals, respectively. The difference was statistically significant (p<0.05). CT-SS of 10.5 or higher was associated with severe pneumonia (100% sensitivity, 81.1% specificity, and an area under the curve of 0.92). Conclusion: COVID-19 vaccination leads to less severe pneumonia based on CT. Fully and partially vaccinated patients with COVID-19 pneumonia have less lung involvement compared to unvaccinated patients. Visual observation by CT imaging provides additional evidence to support the clinical effectiveness of vaccination.","PeriodicalId":503698,"journal":{"name":"Medical & Clinical Research","volume":"71 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139273599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Update on Vitiligo Target Therapy: A Semi-Structured Systematic Review 白癜风目标疗法的最新进展：半结构化系统综述

Medical & Clinical Research Pub Date : 2023-11-15 DOI: 10.33140/mcr.08.11.04

M. A. Abadie, Hussain Tukmatchy, M. Abadie, P. Ball, Hana Morrissey

引用次数: 0

Early Indication of Long-Term Impact of COVID Injections COVID 注射剂长期影响的早期迹象

Medical & Clinical Research Pub Date : 2023-10-20 DOI: 10.33140/mcr.07.048

引用次数: 0

Bacterial Infections Associated with COVID-19 Infection in Thi-Qar Province, Iraq 伊拉克济加尔省与 COVID-19 感染有关的细菌感染

Medical & Clinical Research Pub Date : 2023-10-10 DOI: 10.33140/mcr.07.049

{"title":"Bacterial Infections Associated with COVID-19 Infection in Thi-Qar Province, Iraq","authors":"","doi":"10.33140/mcr.07.049","DOIUrl":"https://doi.org/10.33140/mcr.07.049","url":null,"abstract":"Background: Bacteriological study of clinical samples obtain from patients hospitalized with COVID-19 acquired bacterial infections. The etiology and antimicrobial resistance of bacteria were reported and used for the latest information on the relationship between bacterial infections and COVID-19. Methods: Clinical samples from COVID-19 patients were collected and analyzed for the presence of bacterial infections. Bacterial species were identified using established microbiological and molecular techniques. Antibiotic susceptibility testing was performed on isolated bacteria. Results: Bacterial infections associated with COVID-19 were studied. 384(29.4%) of patients showing evidence of bacterial infections. A total of 231 patients, accounting for 60.2% of the sample, were identified as male, while 153 patients, representing 39.8% of the sample, were identified as female. A total of 226 isolates (58.8%) were identified as bacterial species, with 158(41.2%) classified as Gram-negative bacteria and the remaining 41.2% classified as Gram-positive bacteria. The proportion of bacterial isolates in the blood was higher than other sites. Antibiotic susceptibility testing revealed varying degrees of resistance.","PeriodicalId":503698,"journal":{"name":"Medical & Clinical Research","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139321058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical &amp; Clinical Research最新文献

Medical & Clinical Research最新文献