Acta Medica Bulgarica最新文献

筛选

英文中文

Detection of predefined bacterial species in the Vaginal Microbiota in SARS-COV-2-Positive Patients 检测 SARS-COV-2 阳性患者阴道微生物群中的预定细菌种类

Acta Medica Bulgarica Pub Date : 2024-03-01 DOI: 10.2478/amb-2024-0004

M. Kovachev, M. Kunchev, S. Kovachev

{"title":"Detection of predefined bacterial species in the Vaginal Microbiota in SARS-COV-2-Positive Patients","authors":"M. Kovachev, M. Kunchev, S. Kovachev","doi":"10.2478/amb-2024-0004","DOIUrl":"https://doi.org/10.2478/amb-2024-0004","url":null,"abstract":"\u0000 Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be found in the vagina of infected women remains unclear; moreover, the impact of the virus on the normal vaginal microbiota is not known.\u0000 \u0000 \u0000 of our study was to identify the vaginal presence of SARS-CoV-2 and detection of predefined bacterial species changes in the vaginal flora of women that tested positive for SARS-CoV-2 infection.\u0000 \u0000 \u0000 \u0000 This prospective study included 40 women, aged 24-47 years, tested for SARS-CoV-2 via nasopharyngeal and vaginal culture (TaqPath ™COVID-19 CE-IVD RT-PCR), and vaginally tested for changes in the vaginal microbiota using the Femoflor® 16 REAL-TIME PCR Detection Kit.\u0000 \u0000 \u0000 \u0000 No one of women in this study was tested positive for vaginal presence of SARS-CoV-2. Three (7.5%) women with sexually transmitted disease were excluded. Irregularities were observed in the vaginal microbiota of 8 (21.6%) out of 37 patients included in the study: 3 (8.1%) from the SARS-CoV-2-positive group and 5 (13.5%) from the SARS-CoV-2-negative group. The remaining 29 (78.4%) women had normal vaginal flora; lactobacilli were found to be dominant. Although results revealed a difference in the vaginal microbiota between the two groups, the differences were not statistically significant (p ≥ 0.05).\u0000 \u0000 \u0000 \u0000 Even though it remains unclear whether SARS-CoV-2 invades the vagina of infected women, there is no significant evidence to suggest that it causes a more frequent disturbance in the vaginal microbiota of infected women compared to that in healthy women.\u0000","PeriodicalId":503338,"journal":{"name":"Acta Medica Bulgarica","volume":"25 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140280105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

首页上一页