{"title":"Gender posture and the voiding efficiency in a boy with dysfunctional voiding","authors":"T.L. Bozhendaev, N. B. Guseva, R. O. Ignatyev","doi":"10.24110/0031-403x-2024-103-4-158-161","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-4-158-161","url":null,"abstract":"Dysfunctional voiding in children without organic pathology of the spinal cord in childhood is now becoming more common. Unproductive voiding with the presence of residual voiding of more than 30% of the functional bladder volume for a long time leads to inflammatory diseases of the lower urinary tract. The physiological process of emptying the bladder requires a certain concentration of the child's attention, controlled activation of voiding reflexes and correct body position, especially for boys. Dysfunctional voiding is often formed in physiologically healthy boys with systematic emptying of the bladder in a sitting position, which disrupts the natural configuration of the pelvic floor muscles. Article represents a clinical case of a child with recurrent urinary infection and ineffective urination at the age of 12 y/o, whose treatment was based on training pelvic reflexes and voiding in a standing position, which in its turn had allowed normalization of the miction parameters and stopped the recurrent low urinary tract infection.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"63 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141922889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Makarova, E. Alexeyeva, O.L. Lomakina, T. Gabrusskaya, N. Ulanova, N. Volkova, A.A. Artemyeva, M. O. Revnova, M. Kostik
{"title":"Attitude towards vaccination among pediatric gastroenterologists and rheumatologists of several Russia regions after the anonymous online survey","authors":"E. Makarova, E. Alexeyeva, O.L. Lomakina, T. Gabrusskaya, N. Ulanova, N. Volkova, A.A. Artemyeva, M. O. Revnova, M. Kostik","doi":"10.24110/0031-403x-2024-103-4-90-99","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-4-90-99","url":null,"abstract":"Vaccination of patients with immune-mediated diseases, such as inflammatory bowel diseases (IBD) and juvenile idiopathic arthritis (JIA), is an actual problem since these patients have an increased risk of developing infectious complications due to immunosuppressive therapy and features of the disease itself. The specialists’ attitude towards vaccination of patients with autoimmune inflammatory diseases has changed dramatically over the past decades: from complete refusal previously to almost complete implementation of the vaccine complex and the use of vaccines outside the national immunization schedule as of now. The purpose of this research was to assess the current attitude of pediatric gastroenterologists (PGs) and rheumatologists (PRs) towards vaccination of patients with IBD and JIA, to study their levels of knowledge and practical skills in this area using the anonymous online survey. Materials and methods used: an anonymous survey of 97 pediatric practitioners was conducted, of which 51 were PGs and 46 PRs. The questionnaire included questions about the physicians’ themselves (gender, experience, facility, academic degree) and their knowledge and approaches to vaccination of patients with IBD and JIA with live and inactivated vaccines during different stages of therapy. Results: most physicians believed that immune-inflammatory diseases are not provoked by vaccination (88% of PGs and 69.6% of PRs). A significant group of physicians (40.3% of PGs and 36.9% of PRs) consider vaccination with live vaccines safe for patients with IBD/JIA in remission while receiving immunosuppressive therapy. Most physicians consider vaccination with live vaccines unsafe in the state of active disease (80.4% of PGs and 71.8% of PRs). Outside of remission, physicians vaccinate such patients with live vaccines extremely rarely. A significant portion of physicians (32.0% of PGs and 21.7% of PRs) do not participate in vaccination considering it the responsibility of primary care pediatric practitioners/family physicians. Still, a significant portion of physicians (18.0% of PGs and 47.8% of PRs) actively discourage vaccination in general during the treatment of an immune-inflammatory disease. Determining antibodies to vaccines before starting immunosuppressive therapy/vaccination is considered appropriate by only 35.2%/47.0% of PGs and 32.5%/67.3% of PRs (р=0,885/0,110, respectively). Some physicians believe that vaccination can provoke an exacerbation of IBD/JIA (13.7%/21.6% of PGs and 21.7%/34.8% of PRs answered in affirmative or “rather yes than no,” respectively). Conclusion: the study revealed a differentiated attitude towards vaccination issues between PGs and PRs. Additional efforts needed in order to change the attitude of physicians of different specialties towards vaccination.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141925439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. A. Shabaev, D. A. Morozov, I. Afukov, V. V. Rostovskaya
{"title":"Importance of video urodynamic studies when choosing a treatment method for children with neurogenic bladder dysfunctions","authors":"S. A. Shabaev, D. A. Morozov, I. Afukov, V. V. Rostovskaya","doi":"10.24110/0031-403x-2024-103-4-54-63","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-4-54-63","url":null,"abstract":"Video urodynamics is the standard for assessment of the lower urinary tract in children with neurogenic urinary disorders aiming to provide more information about the condition of the lower urinary tract v. retrograde urethrocystography. Video urodynamics parameters are used as possible indicators for choosing various surgical treatment options, however, all work is focused on adult patients, and data for the pediatric cohort were not available as yet. The purpose of this research was the evaluation of the role of video urodynamics and retrograde urethrocystography in the selection of effective conservative and surgical treatment of neurogenic urinary disorders in children. Materials and methods used: 112 patients aged 1,8 to 18 y/o with neurogenic urinary disorders were included in the study, of whom 101 were those who had been proven effectively treated with conservative M-cholinoblockers or had successfully undergone minimally invasive surgery as follows: intradetrusor injection of botulinum toxin (n=21), transurethral correction of VUR (n=17), simultaneous execution of two of these interventions (n=22). Based on the results of video urodynamic and cystographic examination of these patients with the CHAID technique, the classification trees were built in order to evaluate the effective treatment (conservative/surgical). Results: the median age of patients was 9,0 years [7,8-12,0]. The first classification tree containing the parameter “presence of VUR according to the results of retrograde cystography.” The sensitivity of the obtained model for the effectiveness of surgical treatment was 83,3% v. 73,2% for conservative treatment. The accuracy was 79,2%. The ROC-AUC value was 0,783. The second classification tree contained the maximum Pves value according to the results of the video urodynamics, presence of hyperactivity, presence of VUR. The sensitivity of the obtained model for the effectiveness of surgical treatment was 93,3% v. 97,6% for conservative treatment. The accuracy was 95,0%. The ROC-AUC value was 0,972. Comparison of ROC-AUC values by the Delong test revealed statistically significant differences between these binary classification metrics (p<0.001). Conclusion: the parameters of video urodynamics have greater diagnostic accuracy in effective prediction of both conservative and surgical treatment methods compared to the retrograde urethrocystography.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"87 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141921902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Kolbe, G.B. Bekmurzayeva, S. Semin, I. Osmanov, E. Tambieva
{"title":"Clinical case of Blount's disease and its differential diagnosis","authors":"O. Kolbe, G.B. Bekmurzayeva, S. Semin, I. Osmanov, E. Tambieva","doi":"10.24110/0031-403x-2024-103-4-162-168","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-4-162-168","url":null,"abstract":"Lower extremities deformation is observed quite often in infants. One of the Blount's disease diagnosis features is the difficulty of its differential diagnosis of when excluded from other conditions such as rickets, rickets-like diseases and physiological curvature of the lower extremities in infants. Article represents the main diagnostic criteria for the abovementioned diseases. A clinical case of a patient with Blount's disease who had deviations in calcium-phosphorus metabolism that in their turn are uncommon for this pathology is described. The entire set of clinical and laboratory signs analysis was carried out in details, which then made it possible to carry out a differential diagnosis and exclude hereditary forms of rickets, primarily hypophosphatemic rickets as the reason for pronounced varus deformity of the legs in a 2.5 y/o pediatric patient. The tactics for further treatment by a specialized practitioner had been determined as well.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"33 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141924588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E.V. Ligskaya, A. A. Korsunskiy, A.V. Eremeyeva, O. Satyshev, D. Kudlay
{"title":"Immune response and the hypoxic complications of lower respiratory tract respiratory infections development in children. A bibliographical review","authors":"E.V. Ligskaya, A. A. Korsunskiy, A.V. Eremeyeva, O. Satyshev, D. Kudlay","doi":"10.24110/0031-403x-2024-103-4-142-150","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-4-142-150","url":null,"abstract":"Pneumonia is one of the most common severe infectious diseases in pediatric practice. Hypoxia is common in children with pneumonia and is one of the main predictors of poor outcome. The role of the central link in the cellular response to hypoxia is played by the family of hypoxia-inducible factors (HIF). HIF-1α is the key regulator of both T- and B-lymphocyte functions. The processes of their maturation are accompanied by the formation of circular DNA fragments, TREC (T-cell Receptor Excision Circle) and KREC (Kappa-deleting Recombination Excision Circle). TREC and KREC are unable to replicate and serve as markers for naive lymphocyte production. In its turn, HIF-1α can be used as a marker for cellular hypoxia. The use of TREC and KREC in assessing the immune system in patients with various immunological and infectious pathologies has already been described. At the same time, HIF-1α has so far been little studied as yet. The purpose of this research was to analyze the scientific bibliographical data on the HIF-1α assessment as a marker for hypoxia as well as the quantitative level of TREC and KREC as markers for the adaptive immune response; to study the bibliographical sources on the effect of hypoxia on the immune response, including as part of lower respiratory tract infections. Methods used: bibliographical research in Scopus, PubMed and Google Scholar with keywords “TREC,” “KREC,” “HIF,” “hypoxia,” “pneumonia,” “immune response,” that was then followed by the search results’ systematization, analysis and synthesis. Results: the analysis of bibliographical sources had allowed the Authors to conclude that there is a possible close connection between acute hypoxia and the formation of an adequate immune response in infectious pathologies. Research in this area is still extremely scarce. At the same time, the prospects for this area determine the need for further fundamental and clinical research. Conclusion: it is of a great scientific and clinical interest to be able to non-invasively assess the degree of acute hypoxia during an ongoing infectious disease by examining urinary HIF-1α levels. Particularly promising is the assessment of the HIF-1α level not only as a regulator of tissue adaptation to acute hypoxia, but also as a modulator of the immune response. Taking into consideration the analyzed data, both TREC and KREC appear to be the optimal markers characterizing the functional state of the adaptive immune system.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"46 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141922989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Possibilities for non-surgical management of patients with hypertrophy and inflammation of the pharyngeal tonsil","authors":"E. Radtsig, O.V. Davydova, A. Kizeva","doi":"10.24110/0031-403x-2024-103-4-136-141","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-4-136-141","url":null,"abstract":"Patients who suffer from pharyngeal tonsil hypertrophy or inflammation are very common visitors in outpatient physicians’ practice. Hypertrophy of the pharyngeal tonsil may be accompanied by persistent difficulty in nasal breathing and complications whilst adenoditis in the absence of a significant impact on the child’s quality of life and associated complications had not been regarded as a ‘pathology’ in pediatric physicians’ practice until the patient is reached the age of 7 to 9 years old. The purpose of this research was to compare the regimens of the use of the homeopathic medications in patients with pharyngeal tonsil hypertrophy or inflammation. Materials and methods used: a single-center controlled randomized observation of the use of homeopathic medications of a single active substance had been conducted in pediatric patients aged 1 to 18 y/o with pharyngeal tonsil hypertrophy or inflammation. The study included patients with pharyngeal tonsil hypertrophy or inflammation who had previously taken homeopathic single-substance medications, including in combination with standard treatment. Depending on the choice of patients (repetition of the homeopathic single-substance medications intake or prophylactic regimen) the patients were then divided into comparison groups. All of the patients had undergone both the routine examination and the ENT endoscopy, the parents’/caregivers’ satisfaction with the treatment results was then assessed using the 5-point Likert scale as well as the incidence of acute respiratory infections (ARI) in children while taking homeopathic medicines (compared to the period without taking them) and the willingness to use homeopathic medicines in the future. Results: after the ENT endoscopy (reduction in the size of the pharyngeal tonsil in 38% of cases, p≤0.001) and the parents’/caregivers’ survey (reduction in the ARI frequency in 62% of cases and high satisfaction with the treatment results), the majority of parents/caregivers have assessed the repetition of the repetition of the homeopathic single-substance medications intake as rather more effective in treatment of patients with inflammation of the pharyngeal tonsil of varying degrees of hypertrophy. Conclusion: the use of homeopathic medicines in patients with pharyngeal tonsil hypertrophy or inflammation has showed good effectiveness. According to the ENT endoscopy results before v. after the treatment and the parents’/caregivers’ survey it is preferable to repeat the homeopathic single-substance medications intake in the next adenoiditis episode. The parents’/caregivers’ readiness to go on with the homeopathic medicines’ intake ranges from 50% to 78%.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"53 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141923886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. M. Shabalov, E. Kornienko, V.G. Arsentyev, M.A. Dmitrienko, N. Dumova, E.M. Petrova
{"title":"Prevalence and clinical features of the hydrogen-and-methane variant of the course of the small intestinal bacterial overgrowth syndrome in children with functional dyspepsia","authors":"A. M. Shabalov, E. Kornienko, V.G. Arsentyev, M.A. Dmitrienko, N. Dumova, E.M. Petrova","doi":"10.24110/0031-403x-2024-103-4-81-89","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-4-81-89","url":null,"abstract":"Prevalence of small intestinal bacterial overgrowth (SIBO) syndrome, improved diagnostic accuracy and therapeutic approaches require further study. The purpose of this research was to evaluate the effect of hydrogen dominant or hydrogen-producing SIBO (H-SIBO) and methane dominant or methane-producing SIBO (M-SIBO) types on the severity of clinical manifestations in children with functional dyspepsia (FD). Materials and methods used: a single-center cross-sectional study of 90 pediatric patients: 41 (45.6%) aged 11.0 [9.0:13.0] y/o with FD, of which 20 (48.8%) girls/21 (51.2%) boys, and 49 (54.4%) evaluatively healthy children (“control group”) aged 12.0 [9.5:13.6] y/o, of whom 27 (55.1%) girls/22 (44.9%) boys. The SIBO was determined with the domestically-produced “Lactophan” hydrogen breathing test by AMA Co., Ltd. (Saint Petersburg, Russia) and the “GastroCH4ECK Gastrolyzer” CH4 & H2 monitor by Bedfont Scientific Ltd. (Harrietsham, Maidstone, Kent, England, UK). Results: SIBO (41/100% and 28/57.1%, p<0.001) and H-SIBO (29/70.7% and 18/36.7%, p=0.045) were statistically significantly more often detected in children with FD than in the control group. The M-SIBO incidence (12/29.3% and 10/20.4%, p=0.467) did not differ statistically significantly between the groups. The methane output at the 60th to 90th minutes of the breathing test was 1.7 to 1.8 times higher in FD patients. The hydrogen threshold values at the 60th minute of the breathing test in FD patients for predicting of complaints were as follows: above 35 ppm (ROC-AUC=0.88, 95% CI=0.61-1.00, SE 87.5%, SP 97.2%) for “Sour taste in the mouth,” and above 33 ppm (ROC-AUC=0.80, 95% CI=0.53-1.00, SE 80.6%, SP 75.0%) for “Diarrhea.” The hydrogen threshold value at the 90th minute of the breathing test for “Flatulence” symptom was 44 ppm (ROC-AUC=0.71, 95% CI=0.36-0.88, SE 60.9%, SP 75.0%). Conclusion: testing for methane had increased the accuracy of SIBO diagnosis by 29.3% in patients with FD, i.e. from 70.7% to 100%! The relationship between the hydrogen and the methane concentrations coupled with the presence of dyspeptic symptoms may require the correction of SIBO in patients with FD.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"11 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141925213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Samoylova, M. Koshmeleva, S. V. Fomina, M.S. Gaun, E. I. Trifonova, V. Yun, D. A. Kachanov, D. Kudlay
{"title":"SIGNIFICANCE OF MEMBRANE AND MOBILE FATTY ACIDS POOLS IN THE TYPE 1 DIABETES MELLITUS COMPLICATIONS PROGRESSION","authors":"Y. Samoylova, M. Koshmeleva, S. V. Fomina, M.S. Gaun, E. I. Trifonova, V. Yun, D. A. Kachanov, D. Kudlay","doi":"10.24110/0031-403x-2024-103-3-139-145","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-3-139-145","url":null,"abstract":"Diabetes mellitus (DM) is one of the fastest growing 21st Century health problems worldwide, including type 1 DM. In the context of the “epidemic” of diabetes among children, taking into consideration the modern possibilities for medical examination and laboratory studies of patients with DM, the diagnosis of risk factors for the development of diabetes and diabetic complications comes to the fore as yet. This bibliographical review represents the current state on the factors influencing the development of type 1 DM and its complications in children and adolescents, including an assessment of the role of fat metabolism and lipids in the pathogenesis of the disease. The data was gathered from databases eLIBRARY.RU, PubMed, Dimensions AI and CyberLeninka for 2001-2023.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141339931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Blokhin, G.I. Gordienko, A. Suyundukova, I. Lobushkova, V. Steshin
{"title":"TREATMENT OPTIONS FOR COUGH IN PEDIATRIC PRACTITIONER’S ROUTINE","authors":"B. Blokhin, G.I. Gordienko, A. Suyundukova, I. Lobushkova, V. Steshin","doi":"10.24110/0031-403x-2024-103-3-122-132","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-3-122-132","url":null,"abstract":"Acute respiratory infections (ARI) are the main reason for morbidity in childhood. In ca. 90% of cases, they are accompanied by cough. The purpose of this research was to study the effectiveness and safety of the STODAL® drug in the treatment of cough in children. Materials and methods used: a multicenter prospective observational non-randomized clinical study was conducted involving 1000 outpatients with ARI aged 2 to 7 y/o and whose cough duration did not exceed 3 days from the onset of the disease. All of them were prescribed and treated with the complex homeopathic anticough drug on the day of their visit to pediatric practitioner in the outpatient hospital facilities. The patients were divided into two age groups as follows: G1 (n=500) of children aged 2 to 4 y/o and G2 (n=500) of children aged 4 years and 1 day old to 7 y/o. Results: on the 7th day of the therapy, a statistically significant decrease in the severity of daytime cough was noted: in G1 the severity of cough decreased by 1.51 points (from 2.16 to 0.65 points, p<0.001) and by 1.56 points (from 2.24 to 0.68 points, p<0.001) in G2. There was no difference in the reduction in daytime cough severity between the groups (p=0.158). The severity of night cough in G1 decreased by 1.16 points (from 1.64 to 0.48 points, p<0.001) and by 1.25 points (from 1.71 to 0.46 points, p<0.001) in G2. There were no differences in the dynamics of the severity of night cough between the groups as well (p=0.135). The proportion of patients whose cough resolved completely or became clinically insignificant on the 7th day of treatment was 98%, these patients were therefore considered recovered. Cough treatment was rated positively by 95.1% of parents/caretakers. Adverse events (AEs) were reported in 5 patients (0.5% of all cases) and there were no serious AEs among them. Conclusion: the effectiveness and safety of the STODAL® drug in the treatment of cough in ARI in children aged 2 to 7 y/o allows recommending a homeopathic drug with complex anti-inflammatory, antitussive and antimicrobial action for its inclusion in the treatment regimens starting from the first days of the disease.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"14 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141340853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. G. Zvonkova, T. Borovik, A.Kh. Ulbashev, T.A. Ogay, P. S. Susloparova, A.M. Tepoyan, O. Lukoyanova, N.N. Semenova, L. Kuzenkova, T. Kazyukova, T. Bushueva
{"title":"RUSSIAN LANGUAGE TRANSLATION AND CROSS-CULTURAL ADAPTATION OF FEEDING AND NUTRITION SCREENING TOOL (FNST) FOR CHILDREN WITH CEREBRAL PALSY","authors":"N. G. Zvonkova, T. Borovik, A.Kh. Ulbashev, T.A. Ogay, P. S. Susloparova, A.M. Tepoyan, O. Lukoyanova, N.N. Semenova, L. Kuzenkova, T. Kazyukova, T. Bushueva","doi":"10.24110/0031-403x-2024-103-3-87-95","DOIUrl":"https://doi.org/10.24110/0031-403x-2024-103-3-87-95","url":null,"abstract":"Children with cerebral palsy (CP) often have feeding and swallowing difficulties, which can lead to malnutrition and low body weight gain and negatively affect growth and development. In order to identify feeding difficulties and malnutrition in children with CP and timely access to specialists, the FNST (Feeding Nutrition Screening Tool) English-language questionnaire has been developed and validated. The purpose of the research was to translate into Russian and carry out a cross-cultural adaptation of the FNST screening tool. Methods used: the translation and cross-cultural adaptation of the questionnaire content consisted of seven stages in accordance with the standards of the International Society for Pharmacoeconomics Research and Evaluation of Results (ISPOR). Preliminary testing of the pre-final version of the tool was conducted with the participation of 30 parents/caretakers of CP patients and 10 practitioners. The stages of the work were carried out at the National Medical Research Center for Children’s Health, I.M. Sechenov First Moscow State Medical University and Moscow State Linguistic University (all three are located in Moscow, Russia). The pre-final version was adopted with minor changes. Results: the final Russian-language adapted 4-point screening tool represents a short and simple questionnaire to identify feeding disorders and malnutrition in children with CP aged 2 to 19 y/o and to ensure the possibility of timely dietary intervention. The translation of the questionnaire into Russian and its cross-cultural adaptation have preserved functional, structural and operational equivalence. Conclusion: a Russian-language version of the FNST questionnaire has been created and adapted for screening for eating disorders in children with CP, which is the first necessary step for its further official validation and implementation.","PeriodicalId":503254,"journal":{"name":"Pediatria. Journal named after G.N. Speransky","volume":"115 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141341639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}