SIGNIFICANCE OF MEMBRANE AND MOBILE FATTY ACIDS POOLS IN THE TYPE 1 DIABETES MELLITUS COMPLICATIONS PROGRESSION

Y. Samoylova, M. Koshmeleva, S. V. Fomina, M.S. Gaun, E. I. Trifonova, V. Yun, D. A. Kachanov, D. Kudlay
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Abstract

Diabetes mellitus (DM) is one of the fastest growing 21st Century health problems worldwide, including type 1 DM. In the context of the “epidemic” of diabetes among children, taking into consideration the modern possibilities for medical examination and laboratory studies of patients with DM, the diagnosis of risk factors for the development of diabetes and diabetic complications comes to the fore as yet. This bibliographical review represents the current state on the factors influencing the development of type 1 DM and its complications in children and adolescents, including an assessment of the role of fat metabolism and lipids in the pathogenesis of the disease. The data was gathered from databases eLIBRARY.RU, PubMed, Dimensions AI and CyberLeninka for 2001-2023.
膜和移动脂肪酸池在 1 型糖尿病并发症进展中的意义
糖尿病(DM)是 21 世纪全球增长最快的健康问题之一,其中包括 1 型糖尿病。在糖尿病在儿童中 "流行 "的背景下,考虑到对 DM 患者进行医学检查和实验室研究的现代可能性,对糖尿病和糖尿病并发症发病风险因素的诊断成为当务之急。这篇文献综述反映了影响儿童和青少年 1 型糖尿病及其并发症发病因素的现状,包括对脂肪代谢和脂质在疾病发病机制中作用的评估。这些数据来自 eLIBRARY.RU、PubMed、Dimensions AI 和 CyberLeninka 等数据库(2001-2023 年)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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