International Journal of Fertility and Womens Medicine最新文献

Influence of adiposity on leptin, LH and androgen levels in lean, overweight and obese PCOS patients. 肥胖对瘦、超重和肥胖多囊卵巢综合征患者瘦素、LH和雄激素水平的影响。

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Gordana LaZovic, Ubavka Radivojevic, Srboljub Milicevic, Svetlana Spremovic

{"title":"Influence of adiposity on leptin, LH and androgen levels in lean, overweight and obese PCOS patients.","authors":"Gordana LaZovic, Ubavka Radivojevic, Srboljub Milicevic, Svetlana Spremovic","doi":"","DOIUrl":"","url":null,"abstract":"Background: Leptin modulates hypothalamic-pituitary-gohadal axis functions.Objective: To assess the influence of leptin on LH, and to investigate the potential association of leptin with body mass index (BMI) and androgen concentrations in women with polycystic ovary syndrome (PCOS).Design: Levels of leptin, LH, FSH, E2, testosterone, and androstenedione were measured.Patients: 91 patients with PCOS were included in this study.Methods: Patients were stratified into three groups according to BMI: normal weight (NW group, N=31), overweight patients (OW group N=30) and obese PCOS patients (Ob group, N=30). Results-Hyperandrogenemia was present in the studied group. A significant correlation was observed between BMI and androgens (both P < 0.01), and between leptin levels and androgens (respectfully for androstenendione P < 0.01 and for testosterone P < 0.05). A positive correlation between the LH and leptin levels in NW (P < 0.05) and OW (P < 0.001) patients was noticed, while negative correlation is seen in the Ob group (P < 0.01). In OW patients the significant positive correlation between leptin levels and androstenendione was found (P < 0.001), after correction for BMI. A linear regression model indicated that leptin concentrations and BMI contributed negatively and significantly (P < 0.001) to LH concentrations.Conclusion: LH secretion in PCOS patients can be viewed as a consequence of the activity of different adipocyte and neuroendocrine factors. The attenuation in basal LH levels in obese PCOS women might be related to a leptin-resistant state.","PeriodicalId":50324,"journal":{"name":"International Journal of Fertility and Womens Medicine","volume":"52 2-3","pages":"82-8"},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27304648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antithrombotic prophylaxis in multiparous women with preeclampsia or intrauterine growth retardation in an antecedent pregnancy. 抗血栓预防在多胎妇女先兆子痫或宫内生长迟缓的前妊娠。

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Gabriele Urban, Patrizia Vergani, Roberta Tironi, Patrizia Ceruti, Emanuela Vertemati, Francesca Sala, Enrico Pogliani, Elizabeth W Triche, Charles J Lockwood, Michael J Paidas

{"title":"Antithrombotic prophylaxis in multiparous women with preeclampsia or intrauterine growth retardation in an antecedent pregnancy.","authors":"Gabriele Urban, Patrizia Vergani, Roberta Tironi, Patrizia Ceruti, Emanuela Vertemati, Francesca Sala, Enrico Pogliani, Elizabeth W Triche, Charles J Lockwood, Michael J Paidas","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To determine whether prophylactic low dose aspirin (LDA) alone or in combination with low-molecular-weight-heparin (LMWH) reduces the recurrence of adverse pregnancy outcome (APO).Study design: In this retrospective cohort study, 84 consecutive multiparous patients with a previous history of severe preeclampsia (sPE) and intrauterine growth restriction (IUGR) (<10%ile) were assigned to receive no treatment, LDA alone, or LDA and LMWH. Odds ratios were calculated from logistic regression models.Results: Combined LDA and LMWH significantly reduced the risk of developing IUGR in the index pregnancy (OR = 0.16, 95% CI: 0.03-0.98). Among women with antecedent sPE (n=52), combined treatment reduced APO in the index pregnancy (OR = 0.08, CI: 0.01-0.96), IUGR (OR = 0.02, CI: <0.01-0.46), and IUGR with sPE (OR = 0.08, CI: 0.01-0.96).Conclusion: Combined treatment with LDA and LMWH is strongly protective against the development of APO in a cohort of women with antecedent APO.","PeriodicalId":50324,"journal":{"name":"International Journal of Fertility and Womens Medicine","volume":"52 2-3","pages":"59-67"},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27304707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Umbilical cord rupture: a case report and review of literature. 脐带断裂1例报告及文献复习。

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Madhusudhan Naidu, Vivek Nama, Mahantesh Karoshi, Vijayasri Kakumani, Richard Worth

引用次数: 0

A continuum of care model for postpartum hemorrhage. 产后出血的连续护理模式。

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Stacie E Geller, Marci G Adams, Suellen Miller

{"title":"A continuum of care model for postpartum hemorrhage.","authors":"Stacie E Geller, Marci G Adams, Suellen Miller","doi":"","DOIUrl":"","url":null,"abstract":"The leading cause of maternal mortality is hemorrhage, generally occurring in the postpartum period. Current levels of PPH-related morbidity and mortality in low-resource settings result from institutional, environmental, cultural and social barriers to providing skilled care and preventing, diagnosing and treating PPH. Conventional uterotonics to prevent PPH are typically not available or practical for use in low-resource settings. In such deliveries, most often taking place at home or in rural health centers, underestimation of blood loss leads to a delay in diagnosis. Deficiencies in communication and transportation infrastructure impede transfer to a higher level of care. Inability to stabilize a patient who is in hemorrhagic shock rapidly results in death. To address these individual factors, we propose a continuum of care model for PPH, including routine use of prophylactic misoprostol or other appropriate uterotonic, a standardized means of blood loss assessment, availability of a non-pneumatic anti-shock garment, and systemization of communication, transportation, and referral. Such a multifaceted, systematic, contextualized PPH continuum of care approach may have the greatest impact for saving women's lives. This model should be developed and tested to be region-specific.","PeriodicalId":50324,"journal":{"name":"International Journal of Fertility and Womens Medicine","volume":"52 2-3","pages":"97-105"},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27304653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Update on ovarian hyperstimulation syndrome: part 2--clinical signs and treatment. 卵巢过度刺激综合征最新进展:第2部分——临床症状和治疗。

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Helge Binder, Ralf Dittrich, Friedrich Einhaust, Jürgen Krieg, Andreas Müller, Richard Strauss, Matthias W Beckmann, Susanne Cupisti

引用次数: 0

Value of fetal echocardiography in diagnosis of congenital heart disease in a Serbian university hospital. 胎儿超声心动图在塞尔维亚大学医院先天性心脏病诊断中的价值。

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Snezana Plesinac, Milan Terzic, Bojan Stimec, Darko Plecas

{"title":"Value of fetal echocardiography in diagnosis of congenital heart disease in a Serbian university hospital.","authors":"Snezana Plesinac, Milan Terzic, Bojan Stimec, Darko Plecas","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Ultrasound examination for each and every pregnancy is being accepted as a standard practice worldwide, and prenatal ultrasound diagnosis of congenital heart disease (CHD) is improving due to both staff education and ultrasound equipment modernization. The objective of this study was to estimate the value and accuracy of fetal echocardiography for diagnosis of fetal CHD in a large tertiary referral center for obstetrics and gynecology.Methods: This study was based on a prospective follow-up of 27,051 consecutive patients at the Institute of Ob/Gyn, Belgrade, during 1999-2003. Out of this population a total of 517 (1.9%) patients were selected for fetal echocardiography. The final diagnosis of congenital heart disease was confirmed or rejected on the basis of autopsy and histopathological findings, for the dead fetuses and newborns, or on the basis of neonatal echocardiography (followed by surgery/invasive diagnostic procedure), for the living neonates.Results: From the total population analyzed, there was 71 gravida (0.26%) with congenital fetal heart disease. In that study group, the most frequent cardiac anomalies were complex congenital heart diseases. Analyzing the outcome, there were 67.6% cases with fetal CHD who delivered live neonates. Out of the 73 fetuses/neonates with CHD, abnormal karyotype was detected in only 9 cases. The parameters of the diagnostic value of fetal echocardiography were as follows: sensitivity 94.4%, specificity 99.8%, positive predictive value 98.5%, negative predictive value 99.1%, and overall diagnostic accuracy 99.0%.Conclusion: Fetal echocardiography has a very high diagnostic accuracy, commending referral of suspected patients to large tertiary referral centers.","PeriodicalId":50324,"journal":{"name":"International Journal of Fertility and Womens Medicine","volume":"52 2-3","pages":"89-92"},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27304650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The paradox of obstetric "near misses": converting maternal mortality into morbidity. 产科“险些”的悖论:将产妇死亡率转化为发病率。

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Roneé E Wilson, Hamisu M Salihu

{"title":"The paradox of obstetric \"near misses\": converting maternal mortality into morbidity.","authors":"Roneé E Wilson, Hamisu M Salihu","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To systematically review evidence of obstetric near-misses and their consequences.Data sources: PUBMED, OVID, and references of retrieved articles were used.Methods of study selection: Only 13 original articles describe the occurrence of obstetric/maternal near-miss morbidity to date. All were included in this review, in addition to other articles related to the epidemiology and consequences of severe acute maternal morbidity.Tabulation, integration, and results: Serious forms of maternal morbidity occur in about 1% of women in the United States compared to 3.01 to 9.05% in some developing settings. Worldwide, the leading causes of near-miss morbidity are hemorrhage and pregnancy-related hypertension or eclampsia/pre-eclampsia. These complications can have lasting effects, and their sequelae may result in maternal illness, injury and disability. Based on severity, we have provided three phenotypes of obstetric near-misses: Class I (near-miss with healthy infant); Class II (near-miss with feto-infant morbidity); Class III (near-miss with fetal/infant death).Conclusion: Obstetric near-misses should be considered as potentially chronic illnesses that warrant follow-up care because the theoretical cycle of near-miss (as postulated in this paper) can only be interrupted by the resolution of residual issues or the mother's death. Some may consider near-miss events to be obstetric successes because ultimately the mother's life was spared, but the consequences of these complications can be overwhelming and enduring.","PeriodicalId":50324,"journal":{"name":"International Journal of Fertility and Womens Medicine","volume":"52 2-3","pages":"121-7"},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27304003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Climacteric symptom control after the addition of low-dose esterified conjugated estrogens to raloxifene standard doses. 在雷洛昔芬标准剂量基础上添加低剂量酯化偶联雌激素后更年期症状的控制。

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Sebastián Carranza-Lira, Ana Luz MacGregor Gooch, Nadia Saldivar, Max Saráchaga Osterwalder

{"title":"Climacteric symptom control after the addition of low-dose esterified conjugated estrogens to raloxifene standard doses.","authors":"Sebastián Carranza-Lira, Ana Luz MacGregor Gooch, Nadia Saldivar, Max Saráchaga Osterwalder","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Hormone therapy (HT) is one the best options for climacteric symptom control; however when women are switched to raloxifene, after several years of HT, they restart with symptoms.Objective: To evaluate the effect of the addition of low-dose esterified conjugated estrogens to the conventional dose of raloxifene in the control of climacteric symptoms.Materials and methods: 14 healthy postmenopausal patients were studied. Climacteric symptoms were evaluated at baseline and 3 months after the beginning of treatment by the Kupperman's index (KI) and by the sum of the symptom evaluations carried out with an analog visual scale called SUMEVA. In all the anthropometric variables were documented, as well as time since menopause and endometrial thickness. At random they were distributed in some of the following groups: I) Raloxifene 60 mg/day (n=7) and II) Raloxifene 60 mg/day plus esterified conjugated estrogens 0.312 mg/day (n=7).Statistical analysis: Differences among the groups, as well as those among baseline and those at the end of treatment, were determined by student's t test for independent samples and paired samples respectively.Results: There were no differences in anthropometric variables, nor in the time since menopause. After three months of treatment the libido alterations vertigo and vaginal dryness were significantly greater in group I. In group II a significant decrease in hot flushes, insomnia, nervousness, vaginal dryness, KI, and SUMEVA were found, as was a significant increase in endometrial thickness.Conclusion: The treatment that is proposed in this study can constitute a temporary alternative during the period of transition from HT to raloxifene.","PeriodicalId":50324,"journal":{"name":"International Journal of Fertility and Womens Medicine","volume":"52 2-3","pages":"93-6"},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27304005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fibroid volume, location and symptoms in women undergoing uterine artery embolization: does size or position matter? 子宫动脉栓塞妇女的肌瘤体积、位置和症状:大小和位置有关系吗?

International Journal of Fertility and Womens Medicine Pub Date : 2007-03-01

Elizabeth Kagan Arleo, Robin M Masheb, Jeffrey Pollak, Shirley McCarthy, Michael G Tal

{"title":"Fibroid volume, location and symptoms in women undergoing uterine artery embolization: does size or position matter?","authors":"Elizabeth Kagan Arleo, Robin M Masheb, Jeffrey Pollak, Shirley McCarthy, Michael G Tal","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the relationship between MRI-determined uterine fibroid size and their location, and fibroid-related symptoms, including quality of life and sexual function, in women with symptomatic fibroids before uterine artery embolization (UAE).Materials and methods: Forty-six women underwent pelvic MRI within four weeks prior to UAE. The MRIs were analyzed and fibroid size and fibroid location were recorded. Women also completed a comprehensive self-report questionnaire within the four weeks prior to the procedure. The questionnaire (Short Form-36 (SF-36) and Female Sexual Function Index (FSFI), respectively, investigated the frequency of fibroid-related symptoms, as well as quality of life and sexual function. Pearson product moment correlation coefficients were used to examine relationships among variables, and ANOVAs were used to determine between-group difference.Results: At baseline, women with symptomatic fibroids had worse quality of life and sexual function scores than healthy controls (p < .05). No fibroid-related symptoms, or aspects of quality of life or sexual function, were significantly correlated with either total uterine volume or largest fibroid volume. No significant differences with respect to fibroid-related symptoms were found between patients with or without subserosal or submucosal fibroids.Conclusions: Women with symptomatic fibroids pre-UAE had impaired quality of life and sexual function, but size and location of fibroids as determined by MRI were not related to fibroid-related symptoms, health-related quality of life, or sexual function.","PeriodicalId":50324,"journal":{"name":"International Journal of Fertility and Womens Medicine","volume":"52 2-3","pages":"111-20"},"PeriodicalIF":0.0,"publicationDate":"2007-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27304657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The most frequent hormone dysfunctions in juvenile bleeding. 青少年出血中最常见的激素功能障碍。

International Journal of Fertility and Womens Medicine Pub Date : 2007-01-01

Gordana Lazovic, Ubavka Radivojevic, Srboljub Milicevic, Verica Milosevic, Svetlana Spremovic

引用次数: 0