International Journal of Nursing Studies最新文献

{"title":"Cost-effectiveness of multidisciplinary transitional care interventions: A systematic review and meta-analysis","authors":"Romain Collet ,&nbsp;Charlotte Groenewoud ,&nbsp;Raymond Ostelo ,&nbsp;Juul van Grootel ,&nbsp;Marike van der Leeden ,&nbsp;Marike van der Schaaf ,&nbsp;Suzanne Wiertsema ,&nbsp;Edwin Geleijn ,&nbsp;Mel Major ,&nbsp;Judith Bosmans ,&nbsp;Johanna van Dongen","doi":"10.1016/j.ijnurstu.2025.105103","DOIUrl":"10.1016/j.ijnurstu.2025.105103","url":null,"abstract":"<div><h3>Background</h3><div>Multidisciplinary transitional care interventions promote care coordination after hospital discharge and address (older) patients' complex care needs related to their physical, nutritional, and/or psychosocial status.</div></div><div><h3>Objective</h3><div>This review aimed to identify, critically appraise, and synthesize evidence on the cost-effectiveness of multidisciplinary transitional care interventions compared to usual care.</div></div><div><h3>Design</h3><div>Systematic review and meta-analysis.</div></div><div><h3>Setting(s)</h3><div>Hospitals and primary care.</div></div><div><h3>Participants</h3><div>Adult patients admitted to a hospital, regardless of their condition, and discharged home.</div></div><div><h3>Methods</h3><div>Medline, Embase, CINAHL, and CENTRAL were searched for randomized controlled trials assessing multidisciplinary transitional care interventions' cost-effectiveness compared to usual care and reporting quality of life or quality-adjusted life years (QALY) from inception to July 2024. Findings were stratified by economic perspective and follow-up duration. Evidence certainty was assessed using Grading of Recommendations Assessment, Development, and Evaluation. The primary outcome was the incremental net monetary benefit (expressed as mean difference). Cost-effectiveness acceptability curves depicted probabilities of cost-effectiveness at various willingness-to-pay thresholds.</div></div><div><h3>Results</h3><div>Thirteen trials, containing 4114 patients, were included. From a healthcare perspective over 12 months, there was “low” certainty that multidisciplinary transitional care interventions reduced healthcare costs (MD, €-3452; 95 % CI, −<!--> <!-->8816 to 1912) while there was no difference in QALYs (MD, 0.00; 95 % CI, −<!--> <!-->0.03 to 0.04) compared to usual care. The probability of cost-effectiveness over 12 months was 90 % at a willingness-to-pay of €0/QALY, decreasing slightly to 84 % at higher willingness-to-pay thresholds (“moderate” certainty). Over six months, cost-effectiveness probabilities ranged from 43 % at €0/QALY to 87 % at €100,000/QALY, exceeding 80 % at a willingness to pay of €50,000/QALY (“low” to “moderate” certainty). From a societal perspective, the probabilities of cost-effectiveness were lower, primarily due to a limited number of studies with conflicting results.</div></div><div><h3>Conclusions</h3><div>Multidisciplinary transitional care interventions demonstrate potential for cost-effectiveness. However, the “low” evidence certainty of most comparisons underscores the need for further research to explore the cost-effectiveness of different types of multidisciplinary transitional care interventions across patient populations and country income levels to identify the most cost-effective strategies.</div></div><div><h3>Registration</h3><div>The review protocol was registered on PROSPERO, CRD42023421423.</div></div>","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105103"},"PeriodicalIF":7.5,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing readiness for advance care planning among community-dwelling older adults with frailty: A mixed-method systematic review","authors":"Miki Fujimoto ,&nbsp;Catherine J. Evans ,&nbsp;Yuxin Zhou ,&nbsp;Yihan Mo ,&nbsp;Jonathan Koffman","doi":"10.1016/j.ijnurstu.2025.105111","DOIUrl":"10.1016/j.ijnurstu.2025.105111","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Given uncertain illness trajectories faced by older adults with frailty and risk of decline and poor outcomes, intervention development for readiness to engage with advance care planning may confer benefits. However, evidence in this area remains limited.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Aim&lt;/h3&gt;&lt;div&gt;&lt;ul&gt;&lt;li&gt;&lt;span&gt;1.&lt;/span&gt;&lt;span&gt;&lt;div&gt;To identify, appraise and synthesise evidence on the components, contexts, processes, and linkages with the causal pathways and outcomes of readiness for advance care planning among community-dwelling older adults with frailty.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span&gt;2.&lt;/span&gt;&lt;span&gt;&lt;div&gt;To construct a logic model to inform intervention development.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;/ul&gt;&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Design&lt;/h3&gt;&lt;div&gt;A mixed-methods systematic narrative review, underpinned by the COM-B system behaviour change model and employing thematic data synthesis.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Data sources&lt;/h3&gt;&lt;div&gt;Primary studies were included using experimental or observational designs, qualitative and quantitative. Eligible studies were identified through searches of four electronic databases from inception to January 19, 2025.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;26 articles met the inclusion criteria. The data synthesis generated 14 themes across the three COM-B system components. The review identified the components of older adults' readiness, such as their limited physical and cognitive capacity for engaging in ACP (capability), influence and involvement of family (opportunity), and their desire to maintain the present and fear of change (motivation). It emphasised that readiness for advance care planning is a dynamic process influenced by family carers' and professionals' attitudes and behaviours, uncertainties inherent in older adults' conditions, as well as healthcare system, political, and social factors. The review also highlighted the uncertainties and ongoing changes involved in readiness, such as fluctuating physical and cognitive capabilities and changeable social situations. Based on these findings, a logic model was constructed to guide intervention development, outlining the components, intended outcomes, and influential factors.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Individual behaviour change models alone are insufficient to demonstrate older adults' readiness for advance care planning, as various external factors can influence their readiness. This emphasised the need for a comprehensive understanding of the contextual factors affecting readiness and the importance of flexibility in adapting interventions accordingly. Continuous assessment and enhancement of an individual's readiness for advance care planning, initiating conversations about what matters to them now, and improving family carers' readiness for advance care planning by assessing family dynamics and relationships are essential in practice. Further research is needed to elucidate the processes and causal pathways between intervention components and intended ou","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105111"},"PeriodicalIF":7.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144098906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on Wang et al. (2024) ‘Comparative effectiveness of delirium recognition with and without a clinical decision assessment system on outcomes of hospitalized older adults: Cluster randomized controlled trial’","authors":"Xi Zhang,&nbsp;Ping Li","doi":"10.1016/j.ijnurstu.2025.105109","DOIUrl":"10.1016/j.ijnurstu.2025.105109","url":null,"abstract":"","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105109"},"PeriodicalIF":7.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143932684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors' response to “Comment on Wang et al. (2024) ‘Comparative effectiveness of delirium recognition with and without a clinical decision assessment system on outcomes of hospitalized older adults: Cluster randomized controlled trial.’”","authors":"Jiamin Wang ,&nbsp;Ying Wu ,&nbsp;Yongjun Huang ,&nbsp;Fangyu Yang","doi":"10.1016/j.ijnurstu.2025.105108","DOIUrl":"10.1016/j.ijnurstu.2025.105108","url":null,"abstract":"","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105108"},"PeriodicalIF":7.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143932685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of nurse-led enhanced supportive care as an early primary palliative care approach for patients with advanced cancer: A randomized controlled trial","authors":"Yun Young Choi ,&nbsp;Bomi Hong ,&nbsp;Sun Young Rha ,&nbsp;Sungkun Cho ,&nbsp;Hye Sun Lee ,&nbsp;Jiyeon Lee","doi":"10.1016/j.ijnurstu.2025.105102","DOIUrl":"10.1016/j.ijnurstu.2025.105102","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Nurses play an important role in providing palliative care. However, few studies have evaluated the effectiveness of nurse-led primary palliative care.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;To evaluate the effect of nurse-led enhanced supportive care as an early primary palliative care approach for advanced cancer patients.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Design&lt;/h3&gt;&lt;div&gt;Randomized controlled trial.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Setting(s)&lt;/h3&gt;&lt;div&gt;This study was conducted at Yonsei Cancer Center in Seoul, Korea.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Participants&lt;/h3&gt;&lt;div&gt;Advanced cancer patients initiating palliative chemotherapy (N = 258) and their family caregivers (N = 120) were enrolled and completed 3-month (n = 182 patients, n = 79 caregivers) and 6-month (n = 141 patients, n = 60 caregivers) follow-up assessments.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Participants were randomly assigned to the intervention or control group (1:1). The intervention group received nurse-led enhanced supportive care, which included symptom management and coping enhancement counseling before each chemotherapy cycle (baseline to 3 months) and was delivered by trained nurses. The control group received symptom monitoring. Family caregivers only participated in the evaluation. The primary outcomes were quality of life (EORTC-QLQ C30), symptoms (ESAS), and coping (Brief COPE) at 3 months. The secondary outcomes were quality of life, symptoms, and coping at 6 months. Self-efficacy for coping with cancer (CBI-3.0 K), and depression among cancer patients and family caregivers (HADS-D) at 3 and 6 months were also evaluated. The data were analyzed using linear mixed models.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The intervention group reported beneficial effects in the following outcomes: 1) Quality of life [role functioning domain at 3 months (1.01 ± 2.34 vs. −&lt;!--&gt; &lt;!--&gt;8.37 ± 2.07; &lt;em&gt;p&lt;/em&gt; = .003 [−&lt;!--&gt; &lt;!--&gt;15.57, −&lt;!--&gt; &lt;!--&gt;3.18]; adjusted &lt;em&gt;p&lt;/em&gt; = .044), 2) coping [active coping at 3 months (0.27 ± 0.16 vs. −&lt;!--&gt; &lt;!--&gt;0.34 ± 0.14; &lt;em&gt;p&lt;/em&gt; = .006 [−&lt;!--&gt; &lt;!--&gt;1.04, −&lt;!--&gt; &lt;!--&gt;0.18]; adjusted &lt;em&gt;p&lt;/em&gt; = .044), and self-distraction (0.22 ± 0.17 vs. −&lt;!--&gt; &lt;!--&gt;0.42 ± 0.15; &lt;em&gt;p&lt;/em&gt; = .004 [−&lt;!--&gt; &lt;!--&gt;1.08, −&lt;!--&gt; &lt;!--&gt;0.20]; adjusted &lt;em&gt;p&lt;/em&gt; = .044) at 3 months]; 3) self-efficacy in coping with cancer [maintaining activity and independence at 3 months (1.45 ± 0.47 vs. −&lt;!--&gt; &lt;!--&gt;0.31 ± 0.42; &lt;em&gt;p&lt;/em&gt; = .006 [−&lt;!--&gt; &lt;!--&gt;2.99, −&lt;!--&gt; &lt;!--&gt;0.52]; adjusted &lt;em&gt;p&lt;/em&gt; = .044)]. The intervention was not effective in reducing symptoms and depression of patients or depression of caregivers (adjusted &lt;em&gt;p&lt;/em&gt; &gt; .05).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;Nurse-led enhanced supportive care as an early primary palliative care approach has demonstrated effectiveness in improving the role functioning domain of quality of life, use of coping strategies, and self-efficacy in maintaining activity and independence among advanced cancer patients. Nurse-led early ","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105102"},"PeriodicalIF":7.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors' response to “Comment on Zhang et al. (2025) ‘Effectiveness of exercise-based interventions in preventing cancer therapy-related cardiac dysfunction in patients with breast cancer: A systematic review and network meta-analysis’”","authors":"Dandan Zhang ,&nbsp;Hexiao Ding ,&nbsp;Ruisi Ma ,&nbsp;Ting Liu","doi":"10.1016/j.ijnurstu.2025.105107","DOIUrl":"10.1016/j.ijnurstu.2025.105107","url":null,"abstract":"","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105107"},"PeriodicalIF":7.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Driving behavior and driving outcomes after acute and critical illness: A systematic review","authors":"Valerie Danesh ,&nbsp;Anthony D. McDonald ,&nbsp;Kellia J. Hansmann ,&nbsp;Leanne M. Boehm ,&nbsp;Han Su ,&nbsp;Tammy L. Eaton ,&nbsp;Kelly M. Toth ,&nbsp;Alejandro C. Arroliga ,&nbsp;Brittany D. Work ,&nbsp;Joanne McPeake","doi":"10.1016/j.ijnurstu.2025.105105","DOIUrl":"10.1016/j.ijnurstu.2025.105105","url":null,"abstract":"<div><h3>Background</h3><div>Adults recovering from hospitalization for acute or critical illnesses often face new or worsening physical and cognitive impairments, which can impact their driving abilities and safety. The purpose of this review is to synthesize evidence on driving behaviors and outcomes in the six months following hospitalization for acute or critical illness to guide patient care, provider recommendations, and future research.</div></div><div><h3>Methods</h3><div>A comprehensive search was conducted on PubMed, CINAHL, PsycINFO, and Cochrane databases from 1997 to October 20, 2023 with forward and backward searches.</div><div>Primary empirical research involving vehicle drivers was included. Studies were excluded if they involved fewer than five participants, or if they focused on acute medical conditions with established driving rehabilitation programs. Two reviewers screened abstracts and full texts, resolving discrepancies through discussion.</div></div><div><h3>Results</h3><div>Nineteen studies met the inclusion criteria. Driving behavior and safety data from these studies were derived from simulators (n = 10), self-reports (n = 8) and administrative/regulatory datasets (n = 1). Simulation studies primarily focused on post-surgical populations, and brake reaction times. Self-report studies highlighted driving suspension, cessation, and perceived safety issues. The heterogeneity of study designs and populations limited formal meta-analyses.</div></div><div><h3>Discussion</h3><div>The evidence on driving safety and behavior post-hospitalization is heterogeneous and sparse, with some studies indicating no significant change in collision rates and others showing increased risks. Consequently, clinicians face challenges in recommendations on return to driving. There is a need for robust study designs and naturalistic driving studies to examine the specific impacts of hospitalization on driving safety and to develop evidence-based guidelines to address discharge planning to answer questions of “when should I return to driving?”</div></div><div><h3>Registration</h3><div>PROSPERO identifier CRD42023464876.</div></div>","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105105"},"PeriodicalIF":7.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on Zhang et al. (2025) ‘Effectiveness of exercise-based interventions in preventing cancer therapy-related cardiac dysfunction in patients with breast cancer: A systematic review and network meta-analysis’","authors":"Da Qian ,&nbsp;Haotian Su ,&nbsp;Xuli Meng","doi":"10.1016/j.ijnurstu.2025.105106","DOIUrl":"10.1016/j.ijnurstu.2025.105106","url":null,"abstract":"","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105106"},"PeriodicalIF":7.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘They never listen’ – Normalised deviance in nursing and midwifery staffing","authors":"Stuart Tuckwood ,&nbsp;Peter Griffiths","doi":"10.1016/j.ijnurstu.2025.105110","DOIUrl":"10.1016/j.ijnurstu.2025.105110","url":null,"abstract":"","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105110"},"PeriodicalIF":7.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of nurse-led interventions on enhancing patient-related outcomes in colorectal cancer management throughout the cancer care continuum: A systematic review and meta-analysis","authors":"Yitong Han,&nbsp;Yujie Han,&nbsp;Wenshan Huang,&nbsp;Yantong Liu,&nbsp;Ziqi Wang,&nbsp;Wei Zhao,&nbsp;Wei Zhang","doi":"10.1016/j.ijnurstu.2025.105100","DOIUrl":"10.1016/j.ijnurstu.2025.105100","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Colorectal cancer ranks third in global incidence and second in cancer-related mortality worldwide. Despite persistent challenges across the care continuum, nurses play a pivotal role in optimizing patient outcomes through tailored interventions. However, robust evidence on the clinical efficacy and optimal delivery of nurse-led interventions remains limited.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;To describe the health problems of the participants and nurse-led interventions in accordance with the Omaha System and summarize evidence on the effects of these interventions throughout the continuum from colorectal cancer screening to survivorship.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Eight databases, namely, Web of Science, the Cochrane Library, the Cumulative Index to Nursing and Allied Health Literature, EMBASE, PubMed, Scopus, China National Knowledge Infrastructure and Wanfang Data, were searched from their inception to May 2024. Additionally, the reference lists of the included studies were examined. Content analysis was applied to identify problems and interventions based on the Omaha System. Meta-analysis and descriptive analysis were adopted. Subgroup analyses were conducted on the basis of the study design, treatment history and mode of intervention delivery.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Twenty-eight studies identified problems and types of nurse-led interventions. There were 13 problems in the psychosocial, physiological and health-related behaviors domains. The nurse-led interventions included teaching, guidance and counseling; case management; and treatments and procedures. Nurse-led interventions improved screening rates for colonoscopy and fecal occult blood testing (odds ratio [OR] = 2.51; 95 % confidence interval [CI]: 2.16 to 2.92; p &lt; 0.001; OR = 6.14; 95 % CI: 1.93 to 19.47; p = 0.002), the adequacy of bowel preparation (OR = 1.69; 95 % CI: 1.40 to 2.03; p &lt; 0.001), stoma self-efficacy (standardized mean difference [SMD] = 2.48; 95 % CI: 0.71 to 4.25; p = 0.006), and quality of life (SMD = 0.72; 95 % CI: 0.21 to 1.22; p = 0.005), and reduced the incidence of stoma complications (OR = 0.28; 95 % CI: 0.18 to 0.42; p &lt; 0.001), anxiety (SMD = −&lt;!--&gt; &lt;!--&gt;1.19; 95 % CI: −&lt;!--&gt; &lt;!--&gt;1.40 to −&lt;!--&gt; &lt;!--&gt;0.99; p &lt; 0.001), and depression (SMD = −&lt;!--&gt; &lt;!--&gt;1.00; 95 % CI: −&lt;!--&gt; &lt;!--&gt;1.20 to −&lt;!--&gt; &lt;!--&gt;0.79; p &lt; 0.001). However, nurse-led interventions were ineffective in reducing distress and addressing unmet supportive care needs.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Nurse-led interventions can reduce stoma complications, anxiety and depression and increase the screening rate for colorectal cancer, the adequacy of bowel preparation, stoma self-efficiency and quality of life. Nevertheless, future rigorous research is needed to validate their effects and inform wider implementation.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Registration&lt;/h3&gt;&lt;div&gt;PROSPERO (CRD42024505730) registered on February 18, 2024.&lt;/di","PeriodicalId":50299,"journal":{"name":"International Journal of Nursing Studies","volume":"168 ","pages":"Article 105100"},"PeriodicalIF":7.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143948705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}